Jurnal Health Sains (JHS)
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Literature Review: The Effect of Lemongrass Extract to Reduce Neurological Diseases in The Elderly
Full text linkNeurology is a field of medicine that focuses on the human brain. However, the elderly experience a natural aging process that causes changes in the brain and nervous system, increasing the risk of developing neurological diseases. One of them is dementia or alzheimer's disease, Parkinson's disease, seizures, stroke, sleep disorders, and others. The purpose of this study was to analyze the effect of lemongrass extract on reducing neurological diseases in the elderly. The research method was a systematic literature review on theses, articles, and books published in the range of 2018-2024. Data were collected from three databases (Google scholar, pubmed, and garuda portal) using the keywords "Lemongrass extract" and "Neurological diseases". The results obtained in this study indicate that lemongrass extract has an effect on reducing neurological diseases in the elderly, which can reduce dementia or alzheimer's disease, parkinson's disease, seizures, stroke, sleep disorders. So by using or consuming lemongrass drinks, lemongrass aromatherapy, lemongrass oil for foot massage, lemongrass decoction compresses, lemongrass extract drugs, lemongrass water foot soaks, lemongrass water for bathing can reduce neurological diseases in the elderly
Effectiveness Of Ai-Based Telemedicine In Improving Treatment Compliance Of Chronic Disease Patients In The Post-Pandemic Era: A Multicenter Study In Indonesia
Full text linkChronic diseases such as hypertension, diabetes, and chronic kidney failure are still major contributors to morbidity and mortality in Indonesia. However, long-term treatment compliance remains low, especially in areas with limited access to healthcare. This study aims to evaluate the effectiveness of an artificial intelligence (AI)-based telemedicine system in enhancing medication adherence among patients with chronic diseases in the post-pandemic era. The study design used a mixed method with a sequential explanatory approach, involving 300 patients from three representative areas (Jakarta, Yogyakarta, and East Sumba). Quantitative data collection was conducted using the Medication Adherence Rating Scale (MARS) instrument before and after the system was implemented for 3 months. Qualitative data were obtained through in-depth interviews with patients and medical personnel. The results showed a significant increase in adherence scores (p<0.001) from an average of 6.8 to 8.9 after the intervention. AI features, such as medication reminders, self-monitoring, and interactive chatbots, have been shown to improve adherence and foster positive habits. Regression analysis showed a positive correlation between the intensity of interaction with the application and increased adherence. In-depth interviews revealed that the system was perceived as a "digital companion" that helped patients adhere to their medication regimen. However, barriers related to digital literacy and connectivity in rural areas remained. This study provides evidence that integrating AI into telemedicine services can be a strategic solution to improve adherence to chronic disease medication in Indonesia. These findings offer recommendations for the development of a national digital health system that is inclusive, adaptive, and data-driven. This research also supports the transformation service digital health as part of the post-pandemic health reform agenda
The Relationship between Platelet Count and Hematocrit with the Severity of Dengue Hemorrhagic Fever at Lendemoripa Christian Hospital – West Sumba – East Nusa Tenggara
Full text linkDengue virus infection remains a significant public health problem in tropical and subtropical regions, including Indonesia. This study aims to evaluate the clinical severity and hematological findings among dengue patients at RSK Lende Moripa, West Sumba, NTT. This retrospective descriptive study collected medical record data of adult patients hospitalized during the study period. A total of 76 patients who met the inclusion criteria were analyzed, with data on gender, age, clinical manifestations, and hematological profiles (platelet count and hematocrit) being examined. Of the 76 patients, 45 (59%) were male, and the majority (63%) were between 18-40 years old. Clinical manifestations showed 41 cases (54%) of Dengue Hemorrhagic Fever (DHF) and 35 cases (46%) of Dengue Fever (DF). There were no cases of Dengue Shock Syndrome (DSS). Significant differences in platelet levels were found between DF and DHF cases (p=0.01), while no significant difference was observed in hematocrit levels (p=0.4). Thrombocytopenia was more severe in DHF patients. Platelet levels are critical in assessing dengue severity, with thrombocytopenia being more prevalent in DHF cases. Monitoring platelet levels is essential for early detection of severe dengue case
Characteristics of Thyroid Nodule Patients Undergoing Radiofrequency Ablation (RFA) at RSUD Dr. Soetomo Surabaya from January 2023 to December 2024
Full text linkThe availability of platelets in the Blood Donor Unit (UDD) of the Indonesian Red Cross (PMI) is relatively high each year. National data show that the number of platelet bags collected in 2019 reached 767,680 bags, increasing to 957,397 bags in 2021. However, the surge in dengue fever cases coinciding with the COVID-19 pandemic has nearly doubled the demand for concentrated platelets (TP) in hospitals since 2021. One method to extend platelet shelf life is the addition of platelet additive solution (PAS), which has not yet been implemented in Indonesia. This study aims to determine whether TP obtained through the buffy coat leukofiltered pooling method and stored with PAS can improve platelet quality during storage. The research methodology includes platelet quality analysis using several parameters, including platelet count, pH stability, and aggregation testing through adenosine diphosphate (ADP) examination of TP products over the storage period from day 0 to day 7. The results indicate that the addition of PAS helps maintain platelet quality, stabilize pH levels, and preserve platelet function during storage. This is made possible by the presence of key PAS components such as glucose, sodium acetate, sodium chloride, phosphate, magnesium, and potassium, which contribute to platelet stability and viability. The implications of this study suggest that implementing PAS in TP storage could serve as an effective solution for enhancing platelet availability while maintaining quality over an extended period. Therefore, adopting PAS in Indonesia’s platelet storage system could be a significant innovation to support blood supply sustainability, particularly in medical emergencies such as dengue fever outbreaks and pandemics
Gender Differences in Rheumatic Heart Disease: Data from a District Hospital in Cirebon, Indonesia
Full text linkRheumatic heart disease (RHD) has a high prevalence in low- and middle-income countries, including Indonesia. Gender is among the sociodemographic factors that can influence RHD prevention and management strategies. This study aims to describe the clinical profile of RHD patients, with a focus on gender differences. This cross-sectional study was conducted at Hasna Medika Cardiovascular Hospital in Cirebon, Indonesia. This study included RHD patients in the outpatient clinics, either who came for routine treatment or were newly diagnosed with RHD. Patients’ demographic and clinical data were collected through medical records from January 2023 to December 2023. A total of 157 patients’ data were analyzed. RHD was more common in women (70.7%) than men (29.3%). The incidence of RHD in women was higher (27.9%) in the age group 60 years old and above than in men (19.6%). The most common valve involved in RHD was the mitral valve, more frequently in women (100%) than men (97.8%), with severe mitral stenosis being the most prevalent valve abnormality in both genders (52.3% in women, 47.8% in men). Women have a higher prevalence of RHD than men. This study emphasises the importance of education and the needed improvement of RHD management strategies, specifically for women, as they have a higher burden of RHD
The Effect of Platelet Aditive Solution In Maintaining the Quality and Function of Concentrated Platelets In The Pooling Method of Buffy Coat Leukofiltered
Full text linkThe availability of platelets in the Indonesian Red Cross (PMI) Blood Transfusion Unit (UDD) has been significantly high, with 767,680 bags collected in 2019, increasing to 957,397 bags in 2021. The dengue fever outbreak alongside the COVID-19 pandemic led to a nearly twofold increase in the demand for concentrated platelets (TP) in hospitals from 2021. However, platelet additive solution (PAS), which can extend platelet shelf life, is not yet utilized in Indonesia. This study aims to investigate whether TP obtained using the buffy coat leukofiltered pooling method and stored with PAS can improve platelet quality during storage. A series of laboratory tests were conducted to evaluate platelet count, pH levels, and aggregation function using ADP inspection, monitored over a storage period from day zero to day seven. The results indicate that the addition of PAS effectively maintains platelet quality, pH stability, and platelet function throughout the storage duration. This is attributed to the nutrient-rich composition of PAS, which contains glucose, sodium acetate, sodium chloride, phosphate, magnesium, and potassium, ensuring the preservation of platelet integrity. The findings highlight the potential benefits of PAS implementation in Indonesia to enhance platelet storage efficiency and availability, particularly during periods of high demand. Future research should explore the optimal PAS formulation for different storage conditions, cost-effectiveness, and clinical efficacy in transfusion settings to support broader adoption of this technology in blood banking
Implementation of Color in the Interior Design of the Pharmacy Laboratory through a Total Ergonomics Approach provides Comfort and Increases Focus in Work
Full text linkInterior design is not only limited to arranging the room to make it look attractive. There are fundamental reasons why we need interior design, which must be able to create a room that is harmonious, aesthetic, meets the demands of its activities and the psychological demands of its community so that the room is functional. The furniture and equipment facilities of the pharmaceutical laboratory have been standardized. For color standardization does not yet exist, it is necessary to analyze the color in the interior design of the pharmaceutical laboratory through a total ergonomics approach to be able to provide comfort and focus for staff. The method used is descriptive analysis method. Color psychology is a theory of color studies related to human psychology. To balance the room, it must also be considered the appropriate color implemented in interior design to achieve balance and harmony in the room. Designing the interior of a pharmaceutical laboratory is not just about implementing the colors we like, but must have sufficient meaning so that it can have an impact on behavior, mood, cognition, focus, and general association. For this reason, it is considered important to study the total Ergonomics approach in order to get the optimal improvement solution. The results of the analysis obtained colors that are suitable to be applied to the interior of the pharmaceutical laboratory include neutral colors of white, light gray, and may slightly apply black as an accent. Besides there are several companion colors to be combined with neutral colors including white heron, crystalline, windmill wings, golden straw, thunder. By implementing these colors, it can provide comfort and focus for laboratory staff to improve performance and productivity
The Relationship Between Physical Activity, Stress And Sleep Duration With Hypertension In Senior High School Adolescents In Palembang City
Full text linkHypertension in adolescents is an emerging public health concern, with its prevalence in Indonesia increasing from 3.11%–4.6% in 2005 to 8.3% in 2008, and it is predicted to continue rising annually. Adolescent hypertension often goes undetected, leading to severe health complications in adulthood if left uncontrolled and untreated. Several lifestyle factors, including physical activity, stress levels, and sleep duration, have been identified as potential contributors to the incidence of hypertension in adolescents. This study aims to analyze the relationship between physical activity, stress, and sleep duration with the incidence of hypertension among high school students in Palembang City.This research adopts an analytical cross-sectional study design, with a total sample of 467 high school students selected based on inclusion and exclusion criteria. Data were analyzed using the Chi-Square statistical test to determine associations between variables. The results indicate a significant relationship between physical activity and hypertension (p = 0.008), as well as between stress and hypertension (p = 0.005). However, no significant relationship was found between sleep duration and hypertension (p = 0.054) These findings suggest that low physical activity and high-stress levels contribute to hypertension in adolescents, emphasizing the need for preventive strategies such as promoting regular physical exercise and stress management programs in schools. Future research should explore longitudinal studies to assess the long-term effects of adolescent hypertension, intervention-based research to determine the effectiveness of physical activity programs, and the potential role of sleep quality rather than duration in blood pressure regulation. This study highlights the importance of early lifestyle modifications to prevent hypertension-related complications in adulthood
The Silent Revolution: A Holistic Strategy To Address Prehypertension In Young And Active Populations
Full text linkPrehypertension is an increasingly prevalent condition among young individuals, particularly those who are physically active. Although not as severe as hypertension, prehypertension can elevate the risk of future cardiovascular diseases. Therefore, it is crucial to implement a holistic approach that integrates exercise, stress management, and dietary changes to manage prehypertension effectively. This study aims to analyze the effectiveness of a holistic approach in addressing prehypertension among young populations through a Systematic Literature Review (SLR). The research methodology follows the PRISMA guidelines by analyzing 32 accredited and relevant international publications. The analysis results indicate that regular physical activity, such as aerobic exercise and High-Intensity Interval Training (HIIT), can significantly reduce blood pressure. Additionally, stress management techniques like meditation, yoga, and progressive relaxation have also proven effective in lowering blood pressure. Dietary modifications, including reduced sodium intake, increased potassium consumption, and adherence to healthy eating patterns, contribute positively to managing prehypertension. In conclusion, a holistic approach that combines exercise, stress management, and healthy eating can serve as an effective strategy for preventing and managing prehypertension in young individuals
Comparison of the Effectiveness Between Surgical Therapy and Conservative Therapy in the Management of Tuberculosis Spondylitis: A Comprehensive Systematic Review and Meta-Analysis
Full text linkSpinal tuberculosis (TB) is the most common form of skeletal TB, with the thoracolumbar junction being the most frequently affected region, while cervical spine TB remains relatively rare, accounting for only 3% to 5% of cases. Historically, non-operative treatment was the only option in the pre-antibiotic era. However, with the introduction of effective combination chemotherapy in the early 1950s, the mortality rate for spinal TB significantly decreased to 1%–3%. Despite advancements in medical therapy, surgical intervention remains crucial in cases involving neurological complications and kyphosis prevention, with instrumentation playing an integral role in managing spinal pathologies.
This study aims to evaluate the effectiveness of surgical therapy versus conservative therapy in the management of tuberculosis spondylitis through a systematic review and meta-analysis following PRISMA guidelines and the PICO format. The research includes randomized controlled trials (RCTs), observational, quasi-experimental, and case-control studies, while studies not directly assessing treatment effectiveness were excluded. A comprehensive literature search using PubMed, Sage Journal, The Lancet, and ScienceDirect initially retrieved 1,499 publications. Through a rigorous three-stage screening process, only 10 articles published between 2014 and 2024 were selected for final analysis.
The findings indicate that both conservative anti-TB drug therapy and surgical treatment are safe and effective, particularly for early-diagnosed patients with fewer affected vertebrae. Conservative therapy provides good clinical and radiological outcomes, while surgical intervention offers advantages such as thorough debridement, spinal cord decompression, and improved spinal stabilization. The implications of this study suggest that treatment selection should be tailored based on disease severity and patient-specific conditions. Further research should focus on long-term comparative studies, minimally invasive surgical techniques, and biomechanical modeling to optimize treatment strategies for spinal TB.