Jurnal Health Sains (JHS)
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The Relationship of Lactate Albumin Ratio With Sofa Score As A Predictor of Sepsis Patients in The Intensive Care Room
Full text linkSepsis is a life-threatening organ dysfunction due to dysregulation of the host response to infection which causes systemic changes, namely an increase in the serum lactate/albumin ratio which is associated with mortality. Method:This study is a clinical observational analytical study with a prospective cohort design at fittingAdult patients diagnosed with sepsis in the integrated inpatient ward and intensive care ward at Haji Adam Malik General Hospital, Medan. The subject sampling technique used was non-probability sampling with a consecutive sampling method where 50 subjects were required. Bivariate analysis used the Pearson correlation test and the linear relationship between the lactate-albumin ratio value and the SOFA score used linear regression. A 95% confidence interval with a p value <0.05 was considered significantly significant Results :The results of the research on the first day found that the average LAR H1 was 0.59 + 0.51 (0.12-2.26) and the average SOFA H1 score was 7.32 + 1.88 (7) where an r value of 0.726 was obtained. indicates a high and significant correlation between Lactate Albumin Ratio and SOFA Score as a predictor of sepsis patients (p value = 0.000, p<0.05). On the third day, the average LAR H3 score was 0.12 + 0.29 (0.21-0.47) and the average SOFA H3 score was 9.58 + 2.01 (10) where an r value of 0.33 was found which indicates Very low and insignificant correlation between Lactate Albumin Ratio and SOFA Score as a predictor of sepsis patients (p value = 0.818, p > 0.05). Conclusion:The lactate-albumin ratio was strongly correlated with the SOFA score on the first day of adult patients diagnosed with sepsis in the integrated inpatient ward and intensive care ward
Factors Influencing the Adoption of Healthy Lifestyles Among Indonesian Urban Residents
Full text linkThis research investigates the factors influencing the adoption of healthy lifestyles among urban residents in Indonesia, a country experiencing rapid urbanization. The study addresses the rising challenges associated with physical inactivity, poor dietary habits, and obesity, which are increasingly prevalent in urban areas. Using a socio-ecological model, the research explores how individual, social, and environmental factors contribute to healthy lifestyle adoption. A cross-sectional survey was conducted across major Indonesian cities, with a sample size of 400 respondents. The findings reveal that autonomous motivation and social support significantly influence lifestyle behaviors, while environmental factors such as neighborhood walkability also play a crucial role. However, barriers such as unhealthy retail exposure and time constraints hinder the adoption of healthy behaviors. The study suggests that integrated interventions targeting both individual motivation and urban infrastructure, including improved walkability and healthier food environments, are necessary to promote healthy lifestyles. This research contributes to the socio-ecological framework by incorporating specific urban factors, providing actionable insights for policymakers and urban planners to enhance public health
Analisis Efektivitas Pemberian Edukasi pada Program Makan Bergizi Gratis terhadap Sasaran B3 (Ibu Hamil, Ibu Menyusui, dan Balita Non PAUD) di Desa Ngabenrejo Kabupaten Grobogan Provinsi Jawa Tengah
No full textLatar Belakang : Angka stunting Jawa Tengah tahun 2024 menurut SSGI adalah 17,1% (belum mencapai target 14%). Program MBG Sasaran B3 (ibu hamil, ibu menyusui, dan balita non PAUD) di Jawa Tengah sampai Agustus sudah 18,8% SPPG yang melayani. Kabupaten Grobogan mempunyai angka stunting tertinggi kedua di Jawa Tengah dimana menurut SSGI 2024 yaitu sebesar 25,6% dan Angka Kematian Ibu tertinggi ke-3 dan Angka Kematian Bayi tertinggi di Provinsi Jawa Tengah. Program pemberian MBG sasaran B3 sesuai petunjuk teknis disertai dengan pemberian edukasi yang dilakukan oleh Kader Tim Pendamping Keluarga (TPK). Harapannya program ini selain untuk intervensi spesifik pemberian gizi juga ada pemberian edukasi yang bermanfaat untuk 1000 Hari Pertama Kehidupan (HPK).
Metodologi Penelitian : Metode yang digunakan adalah deskriptif kualitatif dengan mengambil Desa Ngabenrejo Kecamatan Grobogan yang sudah melaksanakan program MBG 3B.
Hasil dan Pembahasan : Mekanisme distribusi MBG Sasaran B3 di Ngabenrejo dilaksanakan di titik yang telah di registrasi sebagai lokasi pengambilan makanan oleh para pendamping. Makanan dikirim oleh SPPG ke lokasi titik dengan sasaran ibu hamil, ibu menyusui, dan balita non paud berdasarkan data Pendataan Keluarga yang selalu diupdate setiap minggu. Kegiatan pengumpulan sasaran sekaligus edukasi dan penimbangan kelompok dilakukan setiap bulan. Edukasi individu diberikan setiap hari saat pembagian MBG baik di titik lokasi maupun diantar ke sasaran apabila tidak hadir.
Kesimpulan : Program MBG sasaran ibu hamil, ibu menyusui, dan balita non PAUD ini efektif sebagai media dalam pemberian edukasi baik kelompok maupun individu kepada sasaran yang juga merupakan keluarga berisiko stunting di Desa Ngabenrejo Kabupaten Grobogan
A Case of Anencephaly with Concomitant Maternal Overweight: Clinical Presentation and Outcome
Full text linkAnencephaly, a lethal neural tube defect (NTD), results from failed cranial neural tube closure during early embryogenesis. Maternal risk factors, including obesity and inadequate periconceptional folic acid intake, are well-established contributors. This report describes a case involving a 29-year-old primigravida with a Body Mass Index (BMI) of 28.03 kg/m² (overweight) who was referred at 39 weeks gestation for delivery following a prenatal diagnosis of anencephaly. The patient had no personal history of chronic illness but had not taken folic acid supplements prior to conception, initiating prenatal vitamins only after pregnancy confirmation. A cesarean section delivered a male infant with classic features of anencephaly. Despite resuscitation, the newborn died shortly after birth. The development of anencephaly in this instance is associated with two key modifiable risk factors: maternal overweight status and the absence of preconceptional folic acid supplementation. Neural tube closure occurs within the first month of pregnancy, often before pregnancy recognition, making folic acid initiation after confirmation too late to prevent NTDs. Maternal overweight or obesity is an independent risk factor that can compromise the fetal environment and potentially alter folate metabolism. This case underscores the critical importance of preconception health counseling, emphasizing the necessity of folic acid supplementation for all women of reproductive age, commencing before conception. This public health measure is particularly crucial for women with elevated BMI
Blood Pressure Management in Acute Ischemic Stroke
Full text linkStroke is a leading cause of death worldwide, with acute ischemic stroke (AIS) being one of its most common forms. AIS occurs when the blood supply to the brain is blocked due to thrombosis or embolism, leading to ischemic brain tissue. Blood pressure management in AIS patients is crucial, as it directly impacts patient outcomes, such as preventing further brain damage, recurrent stroke, and other cerebrovascular complications. The 2019 AHA/ASA guidelines provide distinct strategies for blood pressure management, depending on whether the patient is undergoing reperfusion therapy. For patients with AIS without reperfusion therapy, blood pressure should not be aggressively lowered unless it exceeds 220/120 mmHg. In contrast, for patients undergoing reperfusion therapy, such as IV-tPA or endovascular therapy, blood pressure should be maintained below 185/110 mmHg before and during the procedure. Different antihypertensive agents are used, with short-acting drugs such as labetalol, nicardipine, and hydralazine being commonly employed. Managing blood pressure correctly during AIS treatment is critical in preventing complications such as hemorrhagic transformation and ensuring better long-term neurological outcomes
THE EFFECT OF RESISTANCE TRAINING AND ANTIOXIDANT SUPPLEMENTATION WITH ASTAXANTHIN ON PLASMA MALONDIALDEHYDE (MDA) LEVELS IN ADULTS
Full text linkResistance training has grown in importance for managing oxidative stress, particularly in adults, as it enhances muscle development and overall health. However, it also leads to the formation of reactive oxygen species (ROS), which can result in cellular oxidative damage and potentially hasten the aging process. This review assesses the role of astaxanthin, a powerful antioxidant, in counteracting oxidative stress during resistance training, with a focus on its effects on aging. This study employs a narrative review methodology, evaluating peer-reviewed publications from 2019 to 2024. Keywords used include "Aging," "Antioxidant," "Astaxanthin," "Oxidative Stress," and "Adults." Twenty-five articles were selected for in-depth analysis. The findings suggest that astaxanthin supplementation notably decreases oxidative stress markers, particularly plasma malondialdehyde (MDA) levels, in individuals undergoing resistance training. On a molecular level, astaxanthin activates the Nrf2 pathway, which is responsible for regulating antioxidant enzyme production and supports mitochondrial biogenesis through the PGC-1α pathway. This dual mechanism not only reduces oxidative damage but also enhances energy metabolism, helping maintain cellular function and delaying age-related decline. In conclusion, incorporating astaxanthin supplements into resistance training routines offers promising potential for reducing oxidative stress and promoting healthy aging in adults
Literature Review: The Impact of Entrepreneurial Leadership on The Quality of Health Services
Full text linkThe quality of health services plays a crucial role in achieving better health outcomes globally. Despite the availability of healthcare, poor service quality leads to millions of deaths annually. Entrepreneurial leadership, characterized by innovation, risk-taking, and strategic adaptability, is vital in improving service quality. This literature review examines the role of entrepreneurial leadership in enhancing healthcare service quality, particularly in hospitals. Secondary data was gathered from Google Scholar, PubMed, and ScienceDirect, focusing on studies published between 2020 and 2025. The review reveals that entrepreneurial leadership fosters innovation, increases work engagement, and improves hospital adaptability to evolving patient needs. The findings suggest that hospitals with entrepreneurial leaders can achieve continuous improvements in service quality by adapting to changes, enhancing efficiency, and fostering creativity within their teams. This research emphasizes the need for further studies to explore the direct impact of entrepreneurial leadership on healthcare service quality, as the current literature lacks in-depth analysis of this relationship
Craniocervical Posture Improvement Using Twin Block: A Scoping Review
Full text linkFunctional appliances, such as twin block, effectively treat for skeletal class II malocclusion. The twin block exerts a significant influence on mandibular growth, that contributes to the improvement of craniocervical posture. This scoping review aims to systematically map and evaluate the current literature on the effects of twin block appliance treatment on craniocervical posture. A scoping review followed to PRISMA-ScR guidelines. A comprehensive research conducted in three online databases-Scopus, Pubmed, Springer Link- from 2014-2024. Article selection followed the PCC framework. Studies about the impact of twin block appliance on craniocervical posture were included. A total of 49 articles selected after eliminating duplicates, four articles met the inclusion criteria. The findings from these studies indicate the effect of twin block appliance usage on craniocervical posture. The twin block appliance not only impacts skeletal and dentoalveolar changes, but also craniocervical posture. Evidence suggest that mandibular advancement may induce postural adaptations by altering the craniofacial and cervical spine relationship
Implementation of the Remuneration System on the Level of Job Satisfaction of Nurses in Hospitals
Full text linkNurse job satisfaction is critical for healthcare quality, yet existing research often narrowly focuses on remuneration without considering its interplay with organizational culture, leadership, and post-pandemic demands. This study examines how pay systems interact with non-financial factors to influence nurse satisfaction, aiming to identify context-specific strategies for hospitals. A narrative review analyzed 10 years of literature from PubMed, ScienceDirect, and EBSCOhost using keywords like "remuneration," "nurse satisfaction," and "hospital compensation." Competitive wages boost morale and retention, but holistic satisfaction requires supportive leadership, career growth opportunities, and mental health support. Gaps persist in qualitative insights and regional adaptability. Hospitals should adopt flexible, data-driven pay models aligned with nurses' needs, while future research must employ mixed methods and cross-regional comparisons to refine policies
Neutrophil Lymphocyte Ratio as a Predictor of Chronic Low Back Pain Severity
Full text linkLow back pain is a frequently seen problem in the society and causes loss of productivity. In recent studies, inflammatory mediators and inflammation itself has an efficient role in pain mechanism. We aimed to investigate the association between the neutrophil to lymphocyte ratio level as an inflammatory biomarker with pain severity patients with chronic low back pain. A retrospective analysis was conducted on medical records of low back pain patients between Januari until December 2024 in Neurology Department of Bhakti Rahayu Denpasar Hospital. Seventy-three medical record patients between 27-81 years old were included in the study. The neutrophil-to-lymphocyte ratio (NLR) is calculated by dividing the absolute neutrophil count by the absolute lymphocyte count based on blood samples. The patients were divided into two groups based on pain severity. The average age of the participants was 56,63 years (±15,56) (p= 0,077), with 40 males (54,85) and 33 females (45,2%) with average neutrophil count 5,99 x 109/L (±1,45) (p= 0,200) and lymphocyte count 1,75x 109/L (±0,39) (p= 0,093). NLR cut-off was 3,55 (±0,72) (p= 0,200). Higher NLR correlated with age (r = 0.243, p = 0.038) and pain score (r = 0.394 p < 0.001). High NLR increased the risk of 33, 43 LBP patients experiencing moderate pain (p= <0.001). NLR may be used as a simple and reliable premise independent predictor of pain severity in patients with chronic low back pai