Jurnal Health Sains (JHS)
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Comparison of Conventional and Modern Wound Care in Post-Section Wounds at Cut Mutia Hospital, North Aceh Regency in 2023
Get PDFThe World Health Organization (WHO) sets the average cesarean sections (CS) standard at 5-15% per 1000 births. However, cesarean section rates in private hospitals exceed 30%, compared to 11% in government hospitals. This study investigates the prevalence and complications of surgical wound infections post-cesarean section and the effectiveness of modern wound dressing techniques in reducing these infections. Data analysis reveals cesarean wound infections occur during hospitalization (27%), re-admission (1%), and post-discharge (71%). Surgical wound infections (SWI) significantly increase morbidity, treatment duration, and healthcare costs, with a direct death rate ranging from 3% to 75% globally. The study evaluated modern wound dressings adhering to "moist wound healing" principles, such as hydrocolloids, alginate, and foam, which maintain a moist environment to enhance epithelial cell proliferation, accelerate wound healing, and reduce scarring. Findings indicate that moist wound dressings significantly improve healing outcomes, promoting epithelialization and collagen synthesis, with techniques showing a 30-50% increase in epithelialization and a 2-5 times faster re-epithelialization rate. These results highlight the need for adopting advanced wound care techniques to reduce surgical wound infections and improve patient recovery post-cesarean section. The study implies that healthcare providers should integrate modern wound care practices to enhance maternal health outcomes globally
Surrogate Biomarker to Identify Obesity and Predict Cardiovascular Disease Risk: A Systematic Review
Get PDFThe study investigates the relationship between obesity and cardiovascular disease (CVD) risk, comparing the use of body mass index (BMI) versus other biomarkers in predicting CVD risk among obese individuals. It conducts a systematic literature review following the PRISMA guidelines, searching databases for relevant articles published from 2017-2022. The review analyzes 12 eligible articles and finds that factors beyond just BMI, such as genetics, physical activity, metabolic disorders, previous heart disease history, nutrition, fat distribution, and changes in BMI, can significantly impact the prognosis of heart disease in obese individuals. Importantly, the study shows that measures of fat distribution, like waist-to-height ratio, waist circumference, log-transformed body shape index (LBSIZ), and the ratio of visceral adipose tissue (VAT) to subcutaneous adipose tissue (SAT), are superior to BMI in predicting CVD risk among those with obesity. The key takeaway is that while obesity is strongly linked to CVD risk, BMI alone often fails to predict that risk accurately. Fat distribution measures may be a more effective tool for identifying obesity status and predicting associated CVD risk compared to relying solely on BMI
The Relationship Between Glycemic Control And Lipid Profile In Patients With Type 2 Diabetes Mellitus In Bangli Hospital
Get PDFDiabetes Mellitus (DM) type 2 is susceptible to diabetic dyslipidemia, which is one of the factors in increasing the risk of complications from cardiovascular disease. The aim of this study was to determine the relationship between glycemic control and lipid profile in type 2 DM patients. A cross-sectional study was conducted at the Internal Medicine Polyclinic at Bangli Regional Hospital for the period January 2023-December 2023 and a total of 60 type 2 DM patients met the inclusion criteria. Patients were grouped into type 2 DM patients with controlled glycemic control (HbA1c < 7%) and uncontrolled (HbA1c≥7%). Lower levels of total cholesterol (160,444 ± 30,608 mg/dl vs 203,476 ± 45,471 mg/dl; p= 0.001), triglycerides (125,500 ± 56,019 vs 202,047 ± 91,568; p= 0.002), low-density lipoprotein (K-LDL ) (93,072 ± 28,443 vs 131,571 ± 44,590; p= 0.001) in type 2 DM patients with good glycemic control. High-density lipoprotein (K-HDL) levels (50,022 ± 14,050 vs 41,152 ± 12,619; p = 0.019) were higher in type 2 DM patients with good glycemic control. From statistical tests, a positive correlation was found between total cholesterol levels (r = 0.277; p = 0.032), triglycerides (r = 0.386; p = 0.002) and K-LDL (r = 0.357; p = 0.005) with HbA1c levels. There is a negative correlation between K-HDL (r=-0.366; p = 0.004) and HbA1c levels. The significant correlation between HbA1c and lipid profile shows the importance of glycemic control in type 2 DM patients. This can be explained in the pathogenesis of type 2 DM in the advanced phase. There is a positive correlation between glycemic control (HbA1c) and total cholesterol, triglycerides and K-LDL. There is a negative correlation between glycemic control (HbA1c) and K-HDL
Optimizing Brain-Computer Interfaces for Methampetamine Use Disorder through Quantitative Electroencephalography (QEEG) and Transcranial Doppler Analysis: Article Review
Get PDFA Brain-Computer Interface (BCI) is a system that allows a person to control external devices using only their brain activity. It works by translating brain signals into commands that can be understood by a computer. Several lines of evidence demonstrated the deleterious effect of methamphetamine (MA) on neurological and psychological functions. The use of amphetamines, such as MA, is associated with cerebrovascular complications such as cerebrovascular accidents (CVA) ,hemorrhage, hypoxic damage and vasculitis. Interestingly, while changes to cerebral blood flow (CBF) in response to acute amphetamine exposure have been reported. Transcranial Color Doppler (TCCD) is a non-invasive medical imaging technique that uses ultrasound waves to measure blood flow velocity in the major arteries of the brain, specifically within the circle of Willis. The research paper you referenced explores the use of TCCD as a potential measurement modality for BCIs. Quantitative electroencephalogram (qEEG) is a powerful tool for understanding brain function qEEG can reveal specific brain wave patterns associated with drug addiction, potentially providing insights into the neurobiological mechanisms underlying cravings, withdrawal symptoms, and relapse risk in Methamphetamine User Disorder (MUD). There is growing research interest in using Transcranial dopller as a measurement modality for BCIs.Here are some of the key considerations for using Transcranial doppler in BCIs: Mental Tasks, signal processing and classification, accuracy and reliability. Transcranial doppler provides information about blood flow in specific arteries but lacks detailed spatial information about brain activity. These patterns could vary depending on the type of drug, the severity of addiction, and individual differences. Transcranial doppler in measuring middle cerebral artery (MCA) blood flow velocity parameters (peak systolic velocity (PSV) and mean flow velocity (MFV)). qEEG can help researchers investigate the complex interplay between addiction and other brain disorders, like depression or anxiety. Characteristic qEEG in drugs addiction Increased Theta (4-8 Hz) and delta (1-4 Hz) brain waves are often associated with sleep and relaxation. However, research has shown that individuals with drug addiction may have increased theta and delta activity, particularly in the frontal and temporal regions of the brain. Altered Beta (13-30 Hz) brain waves are generally associated with wakefulness, alertness, and cognitive processing. Studies have observed both increases and decreases in beta activity in individuals with drug addiction, depending on the type of drug, the stage of addiction, and the specific brain regions being examined. The results of this research have important practical implications for building an diagnostic and functional assement with a better understanding of an using technology
Case Study : Observation of Reducing Heartburn Pain in Gastroesophageal Reflux Disease (Gerd) With Hypnotherapy
Get PDFHypnotherapy is a form of psychological treatment that utilizes hypnosis to assist in addressing specific mental and physical ailments. It can also be employed for altering habits. Hypnotherapy operates by inducing a hypnotic state in the subject, lowering brain waves to alpha-theta levels for relaxation and enhanced acceptance of suggestions in the subconscious. The aim is to improve psychological issues, emotions, and conduct. The study was carried out on two patients at the Lee Chen Thung Primary Clinic in Jakarta, Indonesia. Sampling was conducted by adhering to specific criteria for selection and administering the GERD-Q questionnaire. The patients included in the study had to have GERD-Q scores higher than 7 and frequently use PPIs for their stomach issues. Management of GERD can be done with drug therapy or pharmacology and non-pharmacology therapy. One of the non-pharmacology therapies that can be given is hypnotherapy. Patients who satisfied the criteria were provided with hypnotherapy in order to alleviate their heartburn symptoms. The process of hypnotherapy can help the body to stimulate the release of endorphins. Endorphins act as the body's innate pain relievers. Following hypnotherapy, patients underwent eval_uation for 1 week using numeric rating scale. Both patients experienced a decrease in pain levels following hypnotherapy
Implementation of Risk Management in The Medical Records Work Unit Reviewed From National Standards For Hospital Accreditation Through A Systematic Literature Review Approach
Get PDFThe hospital, there is no denying the possibility of unwanted or unexpected negative impacts in work activities, one of which is in the medical records work unit. The aim of the research is to determine the implementation of risk management in the medical records work unit in terms of the National Hospital Accreditation Standards. The research method used was a Systematic Literature Review with a search strategy using Google Scholar results criteria with the keywords "Risk management of medical records work units OR Risk management of medical records work units based on SNARS". The research results were obtained from an in-depth analysis of 6 journal articles, there was a link between the journal articles reviewed and the implementation of risk management in the medical records work unit in terms of the National Hospital Accreditation Standards where the problems found on average occurred in MIRM 12 Standards related to the determination of diagnosis code standards , procedure/action codes, symbols, abbreviations and their meanings, MIRM Standard 13 relating to the provision of medical records for each patient in hospitals, MIRM Standard 13.2 relating to hospital regulations which identify those who have the right to fill in patient medical records and determine the contents of medical records and format medical records, MIRM Standard 13.3 relates to filling in medical records by Professional Care Providers (PPA) by writing identification after the recording is made and MIRM Standard 13.4 relates to performance improvement efforts and hospitals regularly evaluating or reviewing medical records. The risk levels in the medical records work unit from these articles show that the risk categories are "Acceptable" (the intensity of risk is reduced to a minimum) to "Substantial" (requires technical improvement)
Stabilitas dan Pengembangan Metode Estimasi Ruxolitinib Dengan RP-HPLC
No full textRuxolitinib adalah obat penghambat Janus Kinase 1 dan 2 oleh Food and Drud Administration (FDA) pada tahun 2011 yang ditetapkan sebagai pengobatan mielofibrosis dengan risiko sedang hingga tinggi. Ruxolitinib memiliki ketidakstabilan terhadap cahaya yang dapat menyebabkan penurunan kadar. Tujuan dari penelitian ini adalah untuk memperoleh metode analisis yang selektif, akurat dan tepat untuk menentukan kadar dan mengetahui stabilitas ruxolitinib. Penentuan kondisi optimum RP-HPLC dari pengembangan metode analisis dengan variasi komposisi fasa gerak, laju alir, konsentrasi buffer dan pH buffer. Metode analisis baru menentukan kadar ruxolitinib secara RP-HPLC menggunakan kolom C18 Hypersil ODS, panjang gelombang 310 nm, komposisi fase gerak asetonitril: H2O: buffer sitrat (75:20:5), volume injeksi 20 μL, buffer sitrat 0,10 M dan pH 5,8. Kurva kalibrasi antara konsentrasi ruxolitinib pada kisaran 1000-1800 μg/mL, koefisien korelasi 0,9997. Akurasi 99,65%, presisi pengulangan 0,17%, presisi antar hari 0,36%, LOD 26,48 μg/ml, dan LOQ 88,26 μg/ml. Penurunan kadar ruxolitinib setelah pemberian paparan asam sebesar 82,56%, basa sebesar 88,01%, cahaya sebesar 69,06%, suhu sebesar 75,29%. Sehingga disimpulkan bahwa metode yang dihasilkan dari pengembangan metode dan validasinya memenuhi kriteria validasi, penentuan kadar ruxolitinib menunjukkan paparan asam, basa, suhu dan cahaya yang tidak stabil
Dyslipidemia And Hypertension Among Indonesian Hajj Pilgrims: A Cross-Sectional Study
Get PDFThere has been an increase in the preval_ence of cardiovascular disease in Indonesia due to an increased preval_ence of hypertension. Cardiovascular disease is the primary cause of morbidity and mortality among Indonesian Hajj pilgrims. Dyslipidemia and hypertension are positively correlated, with dyslipidemia potentially contributing to hypertension through the mechanism of atherosclerosis. The primary objective of this study is to identify the association between hypertension and dyslipidemia among Indonesian hajj pilgrims. A cross-sectional study involving 114,069 participants in total. The Indonesian Hajj pilgrims in 2023 were the research population. Pre-embarkation medical exams were performed by qualified healthcare professionals, and data were taken from Hajj medical service records. Using bivariate analysis and the Chi-Square (χ2) test, the proportions of age and gender were compared between the hypertension and non-hypertension groups. The relationship between triglyceride, HDL, and LDL levels and hypertension was determined through logistic regression analysis. Logistic regression analysis was used to provide a multivariate analysis of the relationship between dyslipidemia and hypertension. The hypertension group has an average age of 60.2 + 11.6 years old (p<0.0001). There was no difference in the effect of gender on hypertension (p=0.105). HDL, LDL, and Triglyceride serum levels significantly affected the preval_ence of hypertension (p<0.0001). Dyslipidemia was a risk factor for hypertension with an OR of 1.084 (1.057-1.112) (95% CI). Dyslipidemia is a risk factor for hypertension. Serum levels of HDL, LDL, and triglycerides affect blood pressure
Dental Health Care Model In Premature Contact Patients With Partial And Complete Removable Denture Installation At Rsgm Semarang Muhammadiyah University
Get PDFProsthodontic specialist dentistry services are services for the patient's rehabilitative needs with the aim of restoring the function of the oral cavity such as teeth and mucosa by paying attention to the comfort and anxiety of the patient during treatment. The complaints that often occur in premature contact patients with partial and complete denture installation are discomfort, pain, anxiety, and bad breath. There is no government policy in providing guidelines for dental and oral health care for patients specifically for prosthodontics. The preparation of a dental and oral health care model for premature contact patients with partial and complete dentures in hospitals. The design of this study uses Research and Development (R&D) with the Quasi experimental method with a pretest posttest control group design. The number of respondents was 10 dental and oral therapists, and 20 patients who used removable dentures with premature contact. Dental and oral therapist respondents were given a pretest, training, followed by a skill assessment by providing care services to patients, and ended with a posttest. Patients were given a pretest and posttest. The instrument of this research is a questionnaire that has been carried out validity and reliability. Le test de validation expert du modèle de soins dentaires et bucco-dentaires a obtenu des résultats décents avec une valeur p = 0.003 et son application a été efficace pour accroître les connaissances des thérapeutes dentaires et buccaux (p = 0,013), ameliorate l'attitude des thérapeutes dentaires et buccaux (p = 0.043), ameliorate les compétences des thérapeutes dentaires et buccaux (p = 0.01), réduire l'anxiété des patients (p = 0.001) et augmenter l'observance des patients (p = 0.001) Modèle de soins dentaires et bucco-dentaires pour les patients ayant un contact dentaire prématuré Les polyprothèses prothétiques amovibles sont efficaces pour améliorer les connaissances, l'attitude et les compétences des thérapeutes dentaires et buccaux, ainsi que pour réduire l'anxiété et améliorer l'observance du patient
The Relationship Between Soft Skills And Daily Performance Values Of Problem Based Learning Of Students Of The Faculty Of Medicine, Swadaya University Gunung Jati
Get PDFSoft skills are an important attribute in medical practice. PBL is one of the learning methods used by the UGJ Faculty of Medicine, where the assessment process and rubric have adapted soft skills. It is important to know whether there is a relationship between soft skills and the daily PBL performance scores of FK UGJ students. Knowing the relationship between soft skills and the daily PBL performance value of FK UGJ students. This study uses descriptive studies, including analytical observational research, primary data in the form of questionnaires, and secondary data in the form of an archive of PBL performance values. 95.4% (228) of the 239 respondents had sufficient problem-solving soft skills, 97.9% (234) of the 239 respondents had sufficient initiative soft skills, 94.6% (226) of the 239 respondents had sufficient soft skills of integrity, 92.1% (220) of the 239 respondents had sufficient communication soft skills, 88.3% (211) of the 239 respondents had sufficient teamwork soft skills. PBL performance values show quite wide variations. Most students score between 35.0 - 40.0. The results of the research show that there is a significant relationship between the five aspects of soft skills and the daily PBL performance scores of FK UGJ students. There is a significant relationship between the five aspects of soft skills and the daily PBL performance scores of FK UGJ student