Eureka Herba Indonesia (EHI - E-Journal)
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The Effect of Cucumber Fruit (Cucumis Sativus L) on pH Saliva at The Rapha-EL Orphanage Foundation
Get PDFIncreasing the pH of saliva will affect oral health. One way to increase the pH of saliva is to chew fruit that is fibrous, crunchy, and contains lots of water. The research objective was to determine the effect of cucumber on salivary pH at the Bina Mandiri Social Orphanage. This type of research is a one-group pretest and posttest group design. The study population was the children at the Rapha-El Orphanage Foundation. The sample size is determined based on the Roscoe formula of 20 people. Methods of data collection by measuring the pH of saliva before and after chewing cucumbers using a digital pH meter. The data that has been collected, is then analyzed by paired t-test. The results showed that there was a difference in the average pH of saliva before and after chewing cucumber (p = 0.001). The conclusion is that there is an effect of chewing cucumber on increasing the pH of saliva in children at the Rapha- El Orphanage Foundation
Benefit of Ginkgo biloba for Dementia
Get PDFDementia is a chronic progressive brain illness syndrome defined by the loss of numerous cognitive processes, including memory, aphasia, apraxia, agnosia, and executive function. Consciousness is usually unaffected. Psychological and behaviour issues are sometimes present. Dementia is caused by a number of diseases and accidents that affect the brain, either directly or indirectly, such as Alzheimer's disease or stroke. Vascular dementia is a loss of thinking capacity caused by disorders that impede blood flow to certain parts of the brain, depriving brain cells of oxygen and nutrients. After Alzheimer's disease, vascular dementia is the second most frequent kind of dementia. This case study looks at a 76-year-old woman who has vascular dementia. The goal of pharmacological management with risperidone in low dose, as well as psychotherapy, in patients is to preserve and maximize function, reduce behaviour problems, relieve caregiver stress, and delay advancement to the next level. Ginkgo Biloba is one of the plants classified as phytopharmacology or medicines derived from of the plant is Ginkgo biloba Plant G. biloba (Gb) is included in the family Ginkgoaceae. In the G. biloba extract has antioxidant, antiviral, anti-inflammatory, and anti-carcinogenic properties. And also have it was stated that G. biloba extract had a good effect on the function of the CNS (central nervous system)
The Potential of Cinnamon as Anti-Depressant
Get PDFDepression is a feeling of loss of interest or pleasure, sadness, feelings of guilt or inferiority, disturbances in sleep or appetite, feelings of tiredness, and poor concentration and the desire to end life. In Indonesia, according to the Indonesian Ministry of Health in 2018, the prevalence of depressive disorders in Indonesia is 6.1%. Based on the 2013 Riskesdas report, the prevalence of suicide in Indonesia is mostly carried out by women, which is around 0.8% compared to men, which has a prevalence of 0.6%. Until now, the first line of depression therapy is the Serotonin Re-Uptake Inhibitor (SSRI) group. Although this drug is effective in improving symptoms of depression, this drug can cause several side effects such as insomnia or drowsiness, weight gain, and sexual dysfunction. Therefore, we need an alternative medicine that can replace conventional medicine which has less side effects. Cinnamon is one of the many plants found in Indonesia which is believed to have the potential to overcome various diseases. Based on previous research, there are many active components contained in cinnamon that have anti-depressant effects. Active components such as Phenol, Cinnamaldehyde, Turmerone, Proanthocyanidin and Linalool as well as Eugenol can provide anti-depressant effects through anti-inflammatory prevention
Effectiveness of Insulin plant in Management of Diabetes Mellitus
Get PDFDiabetes mellitus, to this day, is still one of significant health problems and created significant morbidity and mortalityamong world populations. Current diabetic drugs still have unpleasant side effects and costly price. Seeking new diabetic drugs from natural resources is one of the practical action for alternative management of the disease. Insulin plant, originated from Andes, has been cultivated in Indonesia. Insulin plant is rich in caffeic acid, clorgenic acid, flavonoid, fenolic compound and sesquiterpenic lactone has antihyperglycemic and antioxidant effect that possibly have a role in diabetes management. Several studies have reported potential of insulin plant as antidiabetic agent. This review aims to summarize and organize current literature on effectiveness and role of insulin plant on diabetes mellitus patien
Effectiveness of Ginger in Treating Nausea and Vomiting of Pregnancy
Get PDFNausea and vomiting in pregnancy (NVP) is one of the common main complaint in pregnancy. NVP can be a significant burden to the patient, make a decrease in quality of life, pregnancy threatening or even worse can lead to nutritional loss and death. NVP diagnosed when in first trimester of pregnancy and the other possible cause of NVP is excluded. Management of NVP is included maintaining hydration, nutrition, and lifestyle modification. Also avoiding the smells, food, or activity that can cause nause are necessary. There are some methods to treat NVP including pharmalogical or non-pharmalogical. The non-pharmalogical approach is change nutritional habits, lifestyle and medications. Several pharmalogical agents that can be used to relief the symptoms of NVP are pyridoxine, anti- histamines, metoclopramide, pyridoxine/doxylamine, promethazine and metoclopramide. Some patients also want to try more “natural” medications for NVP like ginger. The pharmacological activity is thought to stand in the pungent principles (gingerols and shogaols) and volatile oils (sesquiterpenes and monoterpenes). The true mechanism of action of ginger is probable to be a gastric effect, to increase tone and peristaltic due to anticholinergic and antiserotonin act. Ginger acts straight to the digestive tract and avoids the CNS side effects common to centrally acting antiemetics. Ginger is available in capsule or syrup form or in candy, cookies, beer, tinctures, teas, sodas, and jam. Nowadays, true dosing is available only if one uses standardized extracts; however, women may choose to use another form of ginger
The Use of Herbal Medicines for Allergic Rhinitis
Get PDFAllergic rhinitis (AR) is an immunoglobulin E–mediated illness that causes inflammation of the nasal mucosa. In recent years, the global incidence and prevalence of AR has been increased. AR has been treated with antihistamines, intranasal corticosteroids, decongestants, intranasal anticholinergics, intranasal cromolyn, leukotriene receptor antagonists, and immunotherapy. However, because many of the present medicines have documented negative side effects, there is a need to look for more effective and safer alternatives. Herbal therapy has long been used to treat the symptoms of AR, but its usefulness and safety have not been validated scientifically. In this review, recent research on the use of herbal medicine as a treatment for allergic rhinitis is collated and critically analyzed. From 2016 to 2021, the data was gathered mostly from English language publications published in journals or research from Pubmed databases. "Herbal medication" and "Allergic Rhinitis" were the terms or keywords used to discover relevant studies. This literature study may be useful in determining the potential utility of herbal medicine as a treatment for allergic rhinitis, determining the underlying mechanisms of action, and identifying natural product candidates for the development of innovative anti-allergic rhinitis drugs in the future
How to Increasing Prolactine Levels of Breastfeeding Mother with Consumption Katuk (Sauropus androgynous(L)Merr) Leaf
Get PDFInadequate breast milk production is the most common inhibiting factor causing the cessation of exclusive breastfeeding practices an effort to increase the rate of secretion and production of breast milk is through the use of traditional herbal medicines such as decoction and extraction of katuk leaf (Sauropus androgynous). Katuk leaf extract (Sauropus androgynous) has been known to have a variety of pharmacological activities. This paper aims to review the botany, phytochemistry, ethnopharmacology, and pharmacological activities of S. androgynous, and discuss the known chemical constituents at work in S. androgynous-induced prolactin levels to increase breast milk in humans. The data presented in this review were collected from published literature as well as the electronic databases of PubMed, CNKI, Web of Science, SCI finder, ACS, Science Direct, Wiley, Springer, Taylor, Google Scholar, and a number of unpublished resources, (ex: books, and Ph.D. and M.Sc. dissertations). Searching for research articles in several databases using certain keywords breast milk human and katuk (Sauropus Androgynus) leaf literature. All abstracts retrieved were screened for inclusion. All types of articles, including case series and case reports, were included due to the lack of herbal katuk leaf clinical trials. Exclusion criteria consisted of non - English and nonhuman articles. In conclusion, there was a significant effect of katuk leaf consumption towards increasing breastmilk production volume
Potential Combination of Xanthone Compounds from Mangosteen Fruit (Garcinia mangostana) with Eugenol Compounds in Basic Leaf (Ocimum sanctum) as Alternative Therapy in Preeclampsia
Get PDFPreeclampsia is a hyperdynamic condition that is syndromed by hypertension and proteinuria after 20 weeks of pregnancy. Preeclampsia incident is the first cause of 6- 8 % number morbidity/mortality maternity and fetus in the world. Preeclampsia is related to the disability of physiology adaptation that can decrease perfusion of uteroplacental. Xanthone derivatives in mangosteen have been reported to possess a wide range of biological properties, including antioxidant and antihypertensive activities. Eugenol is a primary component of basil oil. It is known for its antioxidant, antiinflammatory, and vasorelaxant actions. These beneficial effects of eugenol make it an excellent therapeutic candidate for the treatment of hypertensive disorders of pregnancy. This study wants to analyze the best available research evidence on the potential combination of xanthone compounds from mangosteen fruit (Garcinia mangostana) with eugenol compounds in basil leaf (Ocimum sanctum) as an alternative therapy in preeclampsia. A literature review was conducted in the electronic databases PubMed and Google Scholar using the index terms "xanthone" and "eugenol" and "hypertension" and "preeclampsia." All types of studies were included for this study, such as randomized controlled trials, systematic reviews, literature reviews, and pilot studies published between 2010 and 2021. Articles which not written in English were excluded from the study. This search resulted in 10 papers. Antioxidant properties of mangosteen peel extract compounds derived from xanthone, the most significant component is α-mangosteen and γ-mangosteen. Eugenol is vasorelaxant action by increasing the expression of its target genes, Sarco/endoplasmic reticulum Ca²⁺-ATPase and adequate potassium-calcium- activated potassium channels channel, thereby relaxing vascular smooth muscle cells and decreasing blood pressure. With this review, we suggest that eugenol, which is a vasorelaxant combined with xanthone which is an antioxidant by obstructing free radical and oxidative stress, can be a potent therapeutic for preeclampsia and intend to motivate researchers (e.g., chemistry, biology, pharmaceutical, and therapeutic areas) to provide evidence of these compounds for the management of preeclampsia
The Potency of Ginkgo Biloba in Treating Tinnitus: A Review
Get PDFExtracts of Ginkgo biloba leaves are used for medicinal purposes for at least 5000 years in China. More recently Ginkgo biloba extracts have been used in Western countries. In the USA, Canada and the UK extracts are widely available as nonprescription food supplements. In France and Germany, a standardized dry leaf extract is registered as a drug and is commonly prescribed for. Several studies have been conducted to measure the usefulness and properties of Ginkgo Biloba in connection with the treatment of Tinnitus. This literature review aims to identify the components and the mechanism of action of Ginkgo Biloba in the treatment of tinnitus. The articles selected were all published within the past five years from PubMed. 11 articles were obtained and were included in the review. Based on the articles, The most important active chemical compounds in Ginkgo Biloba are flavonoids (ginkgo-flavone glycosides) and terpenoids (ginkgolides A, B, C, J, and bilobalide). Gingko Biloba has vasoregulatory effect, antagonism of platelet activator factor, antioxidant activity, enhance neuroplasticity and inflammatory. In conclusion, Ginkgo Biloba demonstrated effectiveness in the treatment of tinnitus, through the significant improvement in self-perception of tinnitus loudness and severity.
 
Safety Assessment of Combination of Tinospora crispa Extract, Andrographis paniculata, Cinnamomum burmanii, Syzygium polyanthum and Momordica charantia in Hepar and Renal Function
Get PDFTinospora crispa, Andrographis paniculata, Cinamomum burmanii, Syzygium polyanthum and Momordica charantia contain phenolics and flavonoids which are rich in benefits. Phenolic compounds are compounds that have an aromatic ring with one or more hydroxy groups, compounds derived from plants that have the same characteristics, namely aromatic rings containing one or more hydroxyl groups. Herbal plants, which are rich in phenolic compounds, have the efficacy, among others, as antioxidants, anti- inflammatory, antimicrobial, anti-fungal and prevents tumor growth. The acute toxicity test is a procedure designed to determine the median lethal dose of a substance and its possible mechanism of action and target organs. In simple terms, toxicity can be defined as the ability of a compound that can cause harmful effects or deviate from the biological mechanism in an organism