Eureka Herba Indonesia (EHI - E-Journal)
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    103 research outputs found

    Overview of COVID-19 Vaccination Status in Patients Infected with COVID-19 at the Royal Prima General Hospital Medan

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    Since the start of the COVID-19 pandemic, attempts have been made to provide acquired immunity against COVID-19. Monitoring and evaluating the efficacy and safety of the COVID-19 vaccine is an important process that must always be carried out in order to optimize the control of the spread of COVID-19 infection. This study aimed to provide an overview of the status of COVID-19 vaccination in patients infected with COVID-19 at the Royal Prima General Hospital, Medan, Indonesia. This study was a descriptive observational study. A total of 100 subjects participated in this study. Data analysis was performed using SPSS version 25 in a univariate manner. The majority of patients who have been vaccinated against COVID-19 only experience mild symptoms of COVID-19. The majority of vaccine brands used by confirmed COVID-19 patients are Sinovac. The majority of patients who have received 2 doses of vaccination are still at risk of being infected with COVID-19. The majority of patients who received the COVID-19 vaccination experienced a low clinical degree when infected with COVID-19

    Profile of Liver Cirrhosis Patients at Imelda Pekerja Indonesia General Hospital (RSU IPI) Period January 2020 – December 2021

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    Liver cirrhosis is the result or complication of a chronic liver condition where the liver parenchyma is damaged so that its function decreases. This study aims to study the profile of patients with liver cirrhosis at the Imelda Pekerja Indonesia General Hospital in Medan for the period January 2020 - December 2021. This study is a descriptive observational study. A total of 40 samples of medical records of patients with a diagnosis of liver cirrhosis at the Imelda Pekerja Indonesia General Hospital in (IPI) Medan were included in this study. Univariate analysis in the form of frequency distribution data tabulation was used to present the data. The results showed that most patients with liver cirrhosis were male (72.5%), aged 56-65 years (32.5%), and the main complaint was nausea and vomiting (47.5%). The most physical examination results were ascites (52.5%), abnormal lab results were increased SGPT (75%), SGOT (80%), total bilirubin (85%), prothrombin time (75%) and decreased albumin (85%) and Hb (55%), most of the patients were in the category of Child-Pugh Score B (37.5%) and C (37.5%), and the most complication was hepatorenal syndrome (55%). In conclusion, the profiles of patients with liver cirrhosis are mostly male, aged 56-65 years, with the most complaints of nausea and vomiting and the most physical examination findings of ascites. There was an increase in SGPT, SGOT, total bilirubin, and prothrombin time, as well as a decrease in albumin and Hb

    Effect of Andrographis paniculata on Blood Sugar Levels Through Regulation of Alpha-Glucosidase Enzyme Expression: An In Vivo Study

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    Diabetes mellitus (DM) is a disease characterized by an increase in blood glucose levels caused by insulin deficiency, either absolute or relative. The α-glucosidase enzyme functions to accelerate the absorption of glucose by the small intestine by catalyzing the hydrolytic cleavage of oligosaccharides into monosaccharides. This study aims to explore the potential of AP extract in regulating blood sugar levels through inhibition of α-glucosidase activity in the intestine. This study is an in vivo experimental study. A total of 30 \ rats were divided into a control group and treated with Andrographis paniculata. Examination of blood sugar levels was carried out by spectrophotometry and examination of alpha-glucosidase enzymes by ELISA. Data analysis was performed using SPSS software with univariate and bivariate analysis. Andrographis paniculata extract was able to reduce blood sugar levels and was able to decrease the activity of the alpha-glucosidase enzyme as the dose increased. Andrographis paniculata extract is able to reduce blood sugar levels by inhibiting the activity of the alpha-glucosidase enzyme in the intestine

    Potency of Turmeric (Curcuma longa L.) and Temulawak (Curcuma xanthorrhiza Roxb.) in Handling Coronavirus Disease 2019 (COVID-19)

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    One of the efforts to prevent COVID-19 that can be done is to increase individual immunity. The effort that can be made is to use herbal ingredients as health drinks. Curcuma longa L., or turmeric, has long been known as one of the ingredients used to treat several complaints. Turmeric has a chemical content of carbohydrates (69.4%), curcuminoids, and essential oils (5.8%). Turmeric and curcumin are non-mutagenic, and no reproductive toxicity has been observed. Curcuma xanthorrhiza Roxb, also known as temulawak, contains curcuminoids (1-2%) and essential oils with xanthorrhizol components (31.9%), ß-curcumene (17.1%), arcurcumene (13.2%), camphor (5.4%), γ-curcumene (2.6%), (Z)-γ-bisabolene (2.6%), and (E)-ß-farnesene (1.2%). Empirically, temulawak has been used for generations in Indonesia to treat various digestive disorders, skin complaints, liver and bile disorders

    The Herbal Potential of Ginger (Zingiber officinale Roscoe) and Guava (Psidium guajava L.) as Supplements for the Management of Coronavirus Disease 2019 (COVID-19)

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    Increasing the body's immunity is one of the efforts to prevent infection with COVID-19. This literature review aims to describe the potential of ginger (Zingiber officinale roscoe) and guava (Psidium guajava L.) as supplements for the management of COVID-19. Grated ginger (Zingiber officinale roscoe) is used as a topical medication to treat swelling, rheumatism, and headaches. In vivo tests in rats that were immunosuppressed using cyclophosphamide showed that ginger essential oil given once a day orally for a week could increase the humoral immune response. Meanwhile, guava has high levels of polyphenols such as myricetin and apigenin compounds, ellagic acid, and anthocyanins. The high vitamin C content in guava contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune systems

    Patient Satisfaction Level of Enhanced Recovery after C-Section at Abby Maternal and Child Hospital Lhokseumawe

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    Enhanced recovery after surgery (ERAS) is a multimodal approach to optimize perioperative management and postoperative outcome. In the field of obstetrics, the implementation of ERAS, called enhanced recovery after caesarian section (ERACS), is still quite lagging behind compared to other surgical specialties. This study aims to describe patient satisfaction with the ERACS method in anesthesia services at Abby Maternal and Child Hospital, Lhokseumawe. This study is a descriptive study and was conducted on post-cesarean section patients who were treated at Abby Maternal and Child Hospital, Lhokseumawe. The sampling technique used purposive sampling technique with a population of 46 respondents. The results of the analysis showed that 45 respondents (97.8%) were satisfied with the service at the hospital after undergoing a cesarean section with the ERACS method of pain management at Abby Maternal and Child Hospital, Lhokseumawe. Most respondents experienced mild pain (87%) and were able to mobilize early after cesarean section and carry the baby for breastfeeding (95.7%). The side effects felt were nausea and vomiting in 8 patients (17.4%) and chills in 11 patients (23.6%). In conclusion, the majority of respondents stated that they were satisfied with the ERACS method of pain management at postoperative C-sections

    The Relationship between Sleep Quality and Blood Pressure in Students of the Faculty of Medicine, Universitas Prima Indonesia

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    Poor sleep quality is one of the risk factors for high blood pressure or hypertension in adults. Disorders of the cardiovascular system are believed to be one of the effects of poor sleep quality. This study aims to determine the relationship between sleep quality and cardiovascular performance of students at the Faculty of Medicine, Universitas Prima Indonesia, as assessed by systolic and diastolic blood pressure. This study is an observational study with a cross-sectional approach. A total of 75 subjects participated in this study. Sleep quality was assessed by PSQI, and blood pressure was assessed by an aneroid tensimeter. This study shows that sleep quality is related to blood pressure. Poor sleep quality is associated with increased blood pressure, p<0.05. Sleep quality is related to blood pressure in students of the Faculty of Medicine, Universitas Prima Indonesia

    Relationship between Body Mass Index and Complaints of Low Back Pain (LBP) on Online Motorcycle Taxi Drivers in Medan, Indonesia

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    Low back pain is one of the musculoskeletal conditions caused by a lack of exercise. Worldwide, 37 percent of cases of LBP are related to occupational variables, including prolonged standing or exposure to vibration. Healthcare workers, drivers, and construction workers are also more susceptible to LBP. The purpose of this study was to determine the relationship between body mass index (BMI) and complaints of low back pain on online motorcycle taxi drivers in Medan. This study is an observational study, and as many as 97 respondents participated in this study. Data analysis was carried out with SPSS version 25, where univariate and bivariate analyses were performed. Correlation between body mass index and complaints of LBP, where there is a low correlation and statistically different. An increase in body mass index will tend to be followed by an increase in LBP complaints, although the correlation between the two is low. There is a relationship between body mass index and complaints of low back pain on online motorcycle taxi drivers in Medan, Indonesia

    Potential of Meniran (Phyllanthus niruri L.) and Sambiloto (Andrographis paniculata) as a Supplement to the Management of Coronavirus Disease 2019 (COVID-19)

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    COVID-19 infection with moderate or severe symptoms can cause pneumonia with an opaque appearance that can be detected on a chest CT scan, pulmonary edema, and accumulation of pleural fluid in the lungs. The use of herbs as health drinks is thought to play a role in increasing the body's immunity. Meniran plant (Phyllantus niruri) contains tannins and flavonoids, which are efficacious as immunomodulators. Meanwhile, sambiloto also contains chemical compounds of alkaloids, carbohydrates, resins, saponins, flavonoids, steroids, glycosides, and tannins. Meniran and sambiloto herbs have the potential to increase the system potential to be developed as a supplement to treat COVID-19

    The Relationship between Sleep Quality and the Incidence of Gastroesophageal Reflux Disease (GERD): A Study on Clinical Clerkship Students, Faculty of Medicine, Universitas Prima Indonesia

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    Gastroesophageal reflux disease (GERD) is defined as a gastrointestinal motility disorder caused by the reflux of gastric contents into the esophagus or oral cavity. This results in symptoms or complications if persistent, resulting in a significant reduction in quality of life and morbidity. Several studies have reported an association between nocturnal GERD and sleep disturbances, which can significantly affect the quality of life. This study explores the relationship between sleep quality and the incidence of GERD in clinical clerkship students at the Faculty of Medicine, Universitas Prima Indonesia. This study is a cross-sectional observational study involving 144 clinical clerkship students. The GERDQ was used to diagnose GERD, and the PSQI questionnaire was used to measure sleep quality. Respondents who did not suffer from GERD with good sleep quality were 32 respondents (22.2%). Those who did not suffer from GERD with poor sleep quality were 65 respondents (74.8%), who suffered from GERD with good sleep quality only 1 respondent (10, 8), and 46 respondents (36.2%). There is a significant relationship between sleep quality and GERD in clinical clerkship students at the Faculty of Medicine, Universitas Prima Indonesia

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