Eureka Herba Indonesia (EHI - E-Journal)
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The Potential of Various Cosmetic Preparations of Tomato Fruit (Solanum lycopersicum) in Medicinal Uses: A Systematic Literature Review
Get PDFIn the cosmetic field, tomatoes can be processed into various preparations that can be used to maintain and improve skin health. Extracts or other natural ingredients derived from tomatoes can be used in cosmetic products. This study is a systematic review study with the aim of exploring the potential of various tomato cosmetic preparations in improving health. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potential of various cosmetic preparations of tomato fruit (Solanum lycopersicum) in medicinal uses. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Extracts or other natural ingredients derived from tomatoes can be used in products such as skin-lightening creams, anti-aging face masks, moisturizers, cleansing soaps, and enzyme peels
Antibacterial Activity Test of Gambas Fruit Extract (Luffa Acutangula (L.) Roxb.) against Bacterial Growth Staphylococcus Aureus In Vitro
Get PDFOne aspect that needs attention in dental and oral health is bacterial infection, including infections caused by Staphylococcus aureus bacteria. Staphylococcus aureus is a type of gram-positive bacteria that can be found in various parts of the human body, including the skin and nasal mucus. These bacteria usually do not cause problems if they remain within normal limits. However, when Staphylococcus aureus enters the oral cavity or surrounding tissue, it can cause various dental and oral health conditions. Gambas fruit (Luffa acutangula (L.) Roxb.), which is also known as Oyong fruit from the Cucurbitaceae family, has an antibacterial effect. This study aimed to determine the antibacterial activity of the ethanol extract of Gambas fruit (Luffa acutangula (l.) roxb.) on bacterial growth of Staphylococcus aureus in vitro. This type of research is a laboratory experimental design post-test only control group. Research data were analyzed using testone-way ANOVA with post-hoc LSD. The results showed that there was an inhibition diameter at each concentration of Gambas fruit extract. 25% Gambas fruit extract has an average diameter of 10.8 mm, 12.5% Gambas fruit extract has an average diameter of 9.4 mm, 6.25% Gambas fruit extract has an average diameter of 8 mm, l Gambas fruit extract 3.125% has an average diameter of 6.9 mm. Gambas fruit extract has antibacterial properties with a minimum inhibition level of 25% against the bacterial growth of Staphylococcus aureus
Formulation and Physical Evaluation of CTM Tablets by Direct Compression Method: A Systematic Literature Review
Get PDFThe direct compression method is one of the well-known formulation approaches in tablet manufacture. In this method, the active ingredients and additives of the formulation are mixed together and then compressed into tablets using a special device such as a compression machine. This study is a systematic review that aims to explore the formulation and physical evaluation of CTM tablets by direct compression method. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the formulation and physical evaluation of CTM tablets by direct compression method. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. The direct compression method enables the manufacture of CTM tablets in a single production step, reducing the complexity and time required. The CTM tablet formulation process using the direct compression method involves homogeneous mixing of the raw materials and direct compression of the mixture into tablets using a compression machine. The direct compression method has advantages in production efficiency, simplicity, and cost-effectiveness, controlling the dosage of the drug contained in the tablet, and physical uniformity of the tablet. However, the direct compression method also has drawbacks, such as the risk of material segregation, difficulty in achieving controlled drug release, and the potential for direct effects on the active ingredients. Physical evaluation of tablets involves measuring the weight, thickness, and diameter of the tablets, as well as hardness or compressive strength tests to ensure the physical quality of the tablets produced. Drug release tests and dissolution tests were carried out to ensure that the CTM tablets released the drug consistently and under control according to regulatory requirements. Stability tests and chemical tests were carried out to check the physical and chemical changes of the tablets during storage and to ensure the integrity and purity of chlorpheniramine
Effervescent Powder Activity of the God’s Crown Fruit Extract (Phaleria macrocapa) (Scheff) Boerl) in Rats Model of Alloxan-Induced Balb/C Diabetes Mellitus
Get PDFGod's crown fruit (Phaleria macrocarpa (Scheff) Boerl) is one of the ingredients that can be used as a natural anti-diabetic because of the presence of flavonoids which have activity as antioxidants. This study aimed to determine the anti-diabetic activity of the powder-effervescent God's crown fruit extract in various doses in test animals and to determine the effective dose of the powder-effervescent God's crown fruit extract as an anti-diabetic. This study is an in vivo experimental study. This study used 25 rats (Mus musculus) Balb/c, which were grouped into 5 groups (negative control, positive, and 3 treatment groups). Rats were induced diabetes mellitus with alloxan, then blood glucose levels were assessed. Data analysis was carried out using SPSS software version 25 in univariate and bivariate. There was no significant effect on reducing blood glucose levels in mice treated with effervescent powder of God's crown fruit extract
Formulation and Characterization of Solid Tablets Using Solid Dispersion Matrix Technology: A Systematic Literature Review
Get PDFThe formulation of solid tablet preparations using solid dispersion matrix technology involves the selection of active ingredients, polymer matrices, fillers or enhancers, and lubricants. The active ingredient is the drug component that provides a therapeutic effect to the patient. This study aimed to conduct a systematic review study to explore the formulation and characterization of solid tablet dosage forms using solid dispersion matrix technology. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the formulation and characterization of solid tablet preparations using solid dispersion matrix technology. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Solid dispersion matrix technology is one of the approaches used in the formulation of pharmaceutical preparations, especially solid tablets, to achieve controlled and effective drug release. In this technology, the drug is dispersed homogeneously in a solid polymeric matrix, which acts as a binding agent. The basic principle of solid dispersion matrix technology is that the drug is delivered via gradual release from the polymer matrix
Jamblang (Syzygium cumini (L.)): A Review of Its Flower and Medicinal Uses
Get PDFThe Jamblang flower is a part of the plant that rarely gets attention in the process of exploring its properties. Jamblang flower is a part of the plant that is quite rich in antioxidant compounds. Antioxidants help protect the body's cells from oxidative damage and can help prevent various degenerative diseases such as heart disease, cancer, and premature aging. This study aimed to carry out a systematic review regarding the potential of Jamblang flowers (Syzygium cumini) in medicinal uses. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potency of Jamblang flower (Syzygium cumini) in medicinal uses. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Jamblang flowers have interesting potential health benefits. The active compounds contained in Jamblang flowers, including antioxidants, anti-inflammatory compounds, and anticancer compounds, can provide health benefits for the body
Comparison of Non-Specific Standardization of Moringa (Moringa oleifera): A Systematic Literature Review
Get PDFIn an effort to ensure that Moringa oleifera products available on the market meet certain standards, including cleanliness, authenticity, and safety, non-specific standardization is carried out. This study aimed to carry out a systematic review to explore the non-specific standardization of Moringa oleifera. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the comparison of non-specific standardization of Moringa oleifera. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. The non-specific standardization process for Moringa oleifera involves botanical identification, evaluation of appearance and organoleptic characteristics, measurement of water, ash, and fiber content, as well as microbiological testing and pesticide residues
Formulation and Evaluation of Effervescent Granules Ethanol Extract of Andaliman Fruit (Zanthoxylum acanthopodium DC) with Combination of Citric Acid-Tartaric Acid and Sodium Bicarbonate
Get PDFThe combination of citric acid-tartaric acid and sodium bicarbonate in effervescent granules has an important role in providing an effervescent effect. Citric acid and tartaric acid are organic acids that can react with sodium bicarbonate when they come in contact with water. This reaction results in the release of carbon dioxide gas, which has a splitting effect and makes the effervescent granules dissolve rapidly in water. Research on the formulation and evaluation of effervescent granules of andaliman fruit ethanol extract with a combination of citric acid-tartaric acid and sodium bicarbonate aims to optimize the stability, solubility, and release of the active ingredients from the granules. This study is an experimental research. Evaluation of effervescent granules is carried out in the form of an organoleptic test. This test can be observed directly from the granules through the shape, color, aroma, and taste produced. Granular specific gravity test, namely real specific gravity, compressed specific gravity, flow rate test, angle of repose test, and compressibility. Tests for dispersion time and pH tests were carried out in this study. FI, FII, and FIII meet the requirements of the organoleptic test, compressibility, flow rate, angle of repose, dispersion time, and pH test. Even though the pH test for the 3 formulas found a pH range of 5.5 to 5.7, but still declared to meet the requirements because it is still close to neutral pH. The best influence on the physical properties of granules effervescent, namely in FIII, as seen in the organoleptic test, flow rate, angle of repose, and dispersion time
The potential of Jamblang Bark Actived Carbon (Syzygium cumini) in Reducing Lead Heavy Metal (Pb) Levels
Get PDFJamblang wood, also known as jambolin or jambolan, is a plant that is widespread in various tropical regions, including Indonesia. Jamblang bark has great potential as a source of raw material for making active carbon because it is rich in organic compounds, cellulose, and lignin, which can provide an ideal pore structure to capture and bind heavy metals. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potential of jamblang bark (Syzygium cumini) activated carbon in reducing lead heavy metal (Pb) levels. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Activated carbon produced from jamblang bark (Syzygium cumini) has significant potential in reducing levels of heavy metal lead (Pb) in various wastewater treatment settings, drinking water treatment, and recovery of heavy metals from industrial waste
Content of Medicinal Chemicals in Traditional Herbal Medicine: A Systematic Literature Review
Get PDFJamu is a traditional medicine made from natural ingredients that are known to be inherited from generation to generation for health. The more widespread the use of traditional medicines is, the more opportunities there are for the adulteration of the ingredients. There are even some herbal medicines that contain medicinal chemicals (BKO). Traditional medicines are prohibited from containing BKO because the BKO content in herbal medicine can be a source of danger in herbal medicine. The method used in this research is data collection carried out by searching databases taken from various scientific articles sourced from PubMed, Science Direct, ResearchGate, WoS (Web of Science), and Google Scholar with articles that have been published from 2013 - 2023. The results that have been obtained from several studies that have been carried out show that there is BKO content in traditional herbal medicine that has been circulating in the community, such as paracetamol, mefenamic acid, phenylbutazone, allopurinol, piroxicam, prednisone, and others