Eureka Herba Indonesia (EHI - E-Journal)
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The Potential of Andrographis paniculata as a Supplement for the Management of Benign Prostate Hypertrophy (BPH): A Systematic Literature Review
Get PDFAndrographis paniculata has been studied for their potential protective action on benign prostate hypertrophy (BPH). This polyphenol has been reported to repair the antioxidant defense mechanisms in the prostate, reduce inflammation, and inhibit IGF-I and IGF-II. Andrographis paniculata has been studied for its potential protective action on benign prostate hypertrophy (BPH) and its ability to reduce inflammation in the prostate. This study aimed to explore various scientific evidence related to the exploration of the potential of Andrographis paniculata in the management of benign prostate hypertrophy (BPH). These three studies consistently present data demonstrating the superiority of andrographolide isolate in the apoptosis initiation of prostate cells. Increased apoptosis of prostate cells is believed to cause a decrease in the mass of prostate tissues and organs. The decrease in prostate mass will relieve pressure on the urethral canal and will eliminate complaints of difficulty urinating in patients with BPH. In conclusion, Andrographis paniculata has the potential to supplementation in the management of benign prostate hypertrophy through regulation of prostate cell apoptosis initiation
The Effectiveness of Using Jengkol Peel Extract (Pithecellobium lobatum Benth.) in Inhibits Bacterial Growth Staphylococcus aureus In Vitro
Get PDFStaphylococcus aureus is aerobic bacteria that are gram-positive and are one of the normal human flora on the skin and mucous membranes. Most infections in the oral cavity are caused by Staphylococcus aureus, which is a normal flora in the oral cavity that can turn into a pathogen if trauma or abrasion occurs on the mucosal surface. Jengkol peel is thought to contain tannin compounds, which have the potential as an anti-inflammatory, anti-diarrheal, antioxidant, treatment of infections of the skin and mouth, and treatment of burns. This study aimed to explore the potential of jengkol peel extract (Pithecellobium lobatum Benth.) as an antibacterial Staphylococcus aureus regularly in vitro. This study is an experimental research in vitro, where as many as 7 treatment groups were used in this study. Positive and negative controls and extract concentrations of 5%-80% were used as the treatment group. Analysis of the average diameter of the inhibition of bacterial growth was carried out using SPSS version 25 software. The potential inhibition of jengkol peel extract was in line with the increase in the concentration of jengkol peel extract. The higher the concentration of jengkol peel extract, the greater the inhibition of bacterial growth. Extract concentration of 20% has a comparable inhibition of bacterial growth control positive. Jengkol peel extract effectively inhibits the growth of Staphylococcus aureus bacteria. Jengkol peel extract concentration of 20% has effectiveness in inhibiting bacterial growth equivalent to 0.2% chlorhexidine in vitro
Overview of Environmental Sanitation and Socio-Cultural of Coastal Communities in Fishing Village, Medan Belawan District, Indonesia
Get PDFAn overview of environmental and socio-cultural sanitation is very interesting to explore. Environmental sanitation and the social culture of coastal communities in fishing villages are inseparable aspects of their daily lives. This study aimed to understand the description of environmental sanitation and socio-culture of the coastal community of fishing village, Medan Belawan District, Indonesia, in order to create sustainable and equitable solutions for them. This study is a descriptive observational study. A total of 100 informants were included in this study. Data analysis was carried out univariately to present environmental sanitation and socio-cultural data. Waste processing in the environment is still very bad, where garbage is generally just piled up, and no waste management efforts are carried out. The community also does not have healthy latrines, which shows that sanitation conditions are still not a good report. The majority report also does not have refrigerators as food storage, and the community, in general, has not implemented a clean and healthy lifestyle. The source of clean water and processed drinking water treatment also still show things that are not good. Water sources and processing that are not optimal make the majority of people experience skin problems. The overview of environmental sanitation and the socio-culture of coastal communities in fishing villages shows how important it is to increase efforts to keep the environment clean and maintain cultural values in their daily lives
Formulation and Evaluation of Chewable Tablets from Natural Extracts: A Systematic Literature Review
Get PDFFormulation of chewable tablets from extracts of natural ingredients requires special attention in designing preparations that maintain the quality and stability of the active ingredients. The extract must have the desired pharmacological effect and be proven safe to use. This study aimed to carry out a systematic review in order to explore formulations of chewable tablets made from natural ingredients. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the formulation and evaluation of chewable tablets from natural extracts. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Formulation of chewable tablets from extracts of natural ingredients is an interesting approach in the development of pharmaceutical preparations. Through a selection of appropriate extracts, careful evaluation of stability, and attention to taste and aroma, these chewable tablets can provide significant benefits to patients. However, it is important to carry out careful research and testing to ensure the safety, effectiveness, and quality of these products before they are used in clinical practice
Cambodian Simplicia (Plumeria sp.) Phytochemical Screening Study: A Systematic Literature Review
Get PDFPlumeria phytochemical screening is important to understand the chemical composition of this plant and its potential in the pharmaceutical and health fields. Through phytochemical analysis, researchers can determine the dominant compounds in plants, study their mechanism of action, and evaluate their biological activity. Phytochemical screening can be carried out using sophisticated analytical methods such as chromatography, spectroscopy, and biological assays to deeply understand the phytochemical profile of Plumeria. This study aimed to carry out a systematic review to explore the phytochemical screening of Plumeria sp. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the evaluation of the phytochemical analysis of Plumeria sp. This study follows the preferred reporting items for systematic reviews and meta-Analysis (PRISMA) recommendations. The process of phytochemical screening was carried out qualitatively and quantitatively. Plumeria sp contains various alkaloids, flavonoids, terpenoids, and phenolic compounds
The Relationship between Smoking and the Incidence of Hypertension in Kebun Lada Public Health Center, Binjai, Indonesia
Get PDFHypertension is a cardiovascular disease characterized by an increase in blood pressure. An increase in blood pressure causes a disruption in the distribution of blood to the target organs. The nicotine content in tobacco is believed to play a role in triggering a series of oxidative stress processes in the body. Oxidative stress plays a role in triggering a series of chronic inflammatory processes in the smoker's body. This study aimed to determine the relationship between smoking and the incidence of hypertension in patients at Kebun Lada Public Health Center, Binjai, Indonesia. Cross-sectional analytic observational study. A total of 75 research subjects participated in this study. Data analysis was carried out using SPSS using univariate and bivariate methods to determine the relationship between smoking and the incidence of hypertension. Subjects with normal blood pressure have a habit of not smoking. Meanwhile, the majority of research subjects with smoking habits experienced stage 1 hypertension. In conclusion, there is a relationship between smoking habits and the incidence of hypertension
Comparison of Metabolite Content between Water Extract and Ethanol Extract of Moringa Leaves (Moringa oleifera): A Systematic Literature Review
Get PDFExtraction with water and ethanol are two common methods used to isolate secondary metabolites from Moringa oleifera. Extraction with water usually produces extracts rich in polar compounds, while extraction with ethanol tends to be better at isolating non-polar compounds. This study aimed to carry out a systematic review related to the comparative study of metabolite content between aqueous extracts and ethanol extracts of Moringa oleifera. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the comparison of the secondary metabolite content of aqueous and ethanol extracts of Moringa oleifera. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Moringa leaf water extract has higher flavonoid and phenolic content than the ethanol extract of Moringa leaves. Meanwhile, the ethanol extract of Moringa leaves contains higher alkaloids and triterpenoids than the aqueous extract of Moringa leaves
The Potential of Turmeric Rhizome Extract in the Preparation of Cosmetic Creams and Lotions: A Systematic Literature Review
Get PDFTurmeric (Curcuma longa) is one of the spices that have been used traditionally in medicine and beauty in various cultures for centuries. The utilization of turmeric rhizome as a cosmetic component lotion or cream is believed to be able to enhance the efficacy of these cosmetics. This study aimed to describe the potential of turmeric rhizome extract in cosmetic preparations and lotion. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potential of turmeric in cosmetics. The search was performed using the terms: (1) "turmeric" OR "turmeric" OR" Curcuma longa" OR "Curcuma domestica" OR" turmeric in cosmetic" AND (2) "Curcuma longa" OR "turmeric". A powerful antioxidant and anti-inflammatory, which can help fight signs of aging on the skin. The active compounds of curcumin in turmeric are anti-inflammatory, antimicrobial, and powerful antioxidants. The combination of these properties makes it an attractive choice for use in cosmetics a cream specifically designed for wound healing on the skin. Studies have shown that curcumin in turmeric can reduce sebum production by the sebaceous glands, reducing the likelihood of acne formation. In conclusion, turmeric rhizome extract has the potential to antiaging, wound healing, and anti-acne in cosmetics in the form of cream or lotion
The Potential of Jamblang Root or Java Plum (Syzygium cumini) in Medicinal Uses: A Systematic Review
Get PDFJamblang root has long been used in traditional medicine as a natural remedy for various health conditions. This study aimed to present a systematic review to explore the potential of jamblang roots in the health sector. This study is a systematic literature review in which exploration was carried out literature from various reputable scientific publication databases. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Several studies have shown that jamblang root has anti-inflammatory properties that can help reduce inflammation in the body. In conclusion, jamblang root or java plum (Syzygium cumini) has the potential for anti-diabetic, anti-inflammatory, antioxidant, hepatoprotective, and astringent effects
Effectiveness of Nitrate and Beta-Blocker Drugs in Patients with Angina Pectoris: A Systematic Literature Review
Get PDFAngina pectoris is the most common clinical manifestation of myocardial ischemia and often occurs when the heart needs more blood. The main goals of treatment in patients with unstable angina are relief of symptoms, slowing disease progression, and reducing future events, especially myocardial infarction, and death. This study aimed to explore the literature regarding the effectiveness of nitrate and beta-blocker drugs in angina pectoris patients. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding risk factors and clinical overview of acute kidney injury. The search was performed using the terms: (1) "nitric oxide" OR "beta-blockers" OR "morbidity" OR "mortality" AND (2) "angina pectoris". The literature is limited to clinical studies and published in English. Sublingual nitroglycerin has become the mainstay of treatment for angina pectoris. This drug can be used to relieve acute angina or as a prophylaxis, namely before activities that can trigger angina. Beta-blockers are a type of drug that can be used to relieve angina symptoms and prevent ischemic events through the mechanism of reducing myocardial oxygen demand, reducing heart rate, and myocardial contractility. These drugs work by competitively inhibiting the action of circulating catecholamines at cell membrane beta-adrenergic receptors. In conclusion, nitrate and beta-blocker drugs are the main choices in relieving angina pectoris symptoms