Eureka Herba Indonesia (EHI - E-Journal)
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Java Plum (Syzygium cumini (L.)) Seeds Potentials in Medicinal Uses: A Systematic Literature Review
Java plum seed contains several active compounds, including flavonoids, tannins, and saponins, which are believed to be responsible for its medicinal properties. This study aimed to conduct a systematic literature review to explore the potential of Jamblang or Java plum seeds on health. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potential of jamblang seed in medicinal uses. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Java plum seeds are believed to be beneficial for immune system support. Java plum seeds have anti-cancer properties. Studies have shown that these compounds can inhibit the growth of cancer cells and induce cell death. Java plum seeds have significant anti-inflammatory properties. They are thought to work by inhibiting the production of pro-inflammatory cytokines, which are molecules secreted by cells that are involved in inflammation
The Pharmacological Activity of Jamblang Plant (Syzygium cumini (L) Skeels) Based on Solvent Polarity: A Systematic Literature Review
In recent years, there has been growing interest in the potential medicinal benefits of Syzygium cumini. This is due in part to the plant's rich content of antioxidants, flavonoids, and other phytochemicals. These compounds have been shown to have a variety of beneficial effects, including antidiabetic, anti-inflammatory, and anti-cancer properties. The solvent plays an important role in the extraction of compounds from Syzygium cumini. This study aimed to conduct a systematic review to explore the potential of jamblang plants (Syzygium cumini) based on solvent polarity. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potential of jamblang in medicinal uses based on solvent polarity. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. The solvent plays an important role in the extraction of compounds from Syzygium cumini. The solvent must be able to dissolve the target compounds, but it must not also dissolve other compounds that are not desired. The solvent must also be compatible with the plant material and the extraction method. The solvent must be of the same polarity as the target compounds. For example, polar solvents such as water and ethanol are good for extracting polar compounds, such as flavonoids and anthocyanins. Non-polar solvents such as acetone and methanol are good for extracting non-polar compounds, such as terpenes and steroids
Analysis of Glucose Levels in White Glutinous Rice Bran: A Systematic Literature Review
White glutinous rice bran has lower glucose levels than white glutinous rice. This could be relevant for glycemic management in diabetes sufferers. Lower glucose levels can help reduce blood sugar spikes after food consumption. White glutinous rice bran, with its low glucose content, can be considered a safe and beneficial food alternative for diabetes sufferers. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the analysis of glucose levels in white glutinous rice bran. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. The glucose content in rice bran ranges from 1.5 to 2.5%, a lower value compared to the glucose content in white glutinous rice which reaches around 7.5%. White glutinous rice bran has relatively low glucose levels, making it a potential food option for consumption by diabetes mellitus sufferers
Qualitative Analysis of Medicinal Chemical Content in Packaged Herbal Medicine: A Systematic Literature Review
Qualitative analysis of the medicinal chemical content in packaged herbal medicine is an examination method to determine whether or not there is medicinal chemical content (BKO) in packaged herbal medicine. BKO is a chemical that is not listed in the composition of herbal medicine permitted by the Food and Drug Supervisory Agency (BPOM). The presence of BKO in packaged herbal medicine can endanger consumer health. This study aims to explore qualitative analysis methods for the content of medicinal chemicals in packaged herbal medicine. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potency of qualitative analysis of medicinal chemical content in packaged herbal medicine. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Qualitative analysis of the BKO content in packaged herbal medicine is an important method to ensure the safety of the herbal medicine consumed. Qualitative analysis of BKO content in packaged herbal medicine can be carried out using various methods, including thin layer chromatography (TLC), gas liquid chromatography (GLC), UV-vis spectrophotometry, and mass spectrophotometry (MS)
The Active Compound Content of Jamblang (Syzygium cumini) as an Anti-Breast Cancer
Jamblang is rich in bioactive compounds such as anthocyanins, phenolics, and flavonoids. Anthocyanins, which give jamblang fruit its dark color, have been known for their antioxidant properties that can fight oxidative stress, which is linked to the development of cancer. Phenolics, with their anti-inflammatory and antioxidant properties, provide additional protection to body cells. Flavonoids, with a wide range of biological activities, including anti-cancer properties, could potentially be promising agents in cancer prevention and treatment efforts. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potential of the active compound Jamblang (Syzygium cumini) as anti-breast cancer. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. The jamblang plant has potential as an anti-breast cancer agent. Jamblang plants are rich in active compounds that have anticancer activity, namely anthocyanins, flavonoids, phenolic compounds and carotenoids. These compounds can inhibit cancer cell growth, trigger apoptosis, and inhibit metastasis
Identification of Tannin, Triterpenoid, and Flavonoid Function Groups of Jamblang Plants (Syzygium cumini): A Systematic Literature Review
Identification of the functional groups of tannins, triterpenoids, and flavonoids in jamblang is important to determine the type and content of bioactive compounds found in jamblang. By knowing the type and content of these bioactive compounds, the potential of jamblang as a traditional medicine can be further optimized. This study aims to explore the identification of tannin, triterpenoid, and flavonoid functional groups in jamblang. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the identification of tannin, triterpenoid, and flavonoid functional groups in jamblang (Syzygium cumini). This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Jamblang contains various types of tannins, including catechins, gallotanins, and proanthocyanidins. Jamblang contains various types of triterpenoids, including phytosterols, triterpenoid saponins, and other triterpenoids. Jamblang contains various types of flavonoids, including flavonols, flavanones, and anthocyanins
Identification of Chemical Compounds and Antioxidant Activity of Jamblang Plants (Syzygium cumini): A Systematic Literature Review
Antioxidants are compounds that can protect body cells from damage caused by free radicals, which can contribute to various degenerative diseases and aging. Therefore, research on the antioxidant activity of jamblang is very important to identify its health potential. This study aims to identify the key compounds contained in jamblang and investigate its potential antioxidant activity. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding compound identification and antioxidant activity in jamblang (Syzygium cumini). This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. With quercetin level which reaches 10-20% in jamblang, this suggests that this plant can be a significant natural source of this compound. In general, the results of testing the antioxidant activity of jamblang using various methods show that jamblang has strong antioxidant activity
Effectiveness of Toothpaste from Activated Charcoal as Teeth Whitening: A Systematic Literature Review
Charcoal toothpaste is claimed to have the ability to whiten teeth by removing stains and plaque. The activated charcoal particles in the toothpaste are believed to be able to absorb pigments or substances that cause stains on the tooth surface, such as plaque buildup, food scraps, or colored drinks. This study aimed to carry out a systematic review regarding the exploration of the effectiveness of activated charcoal as teeth whitening. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the effectiveness of toothpaste from activated charcoal as teeth whitening. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. The process by which activated charcoal adsorbs plaque and tooth stains involves its adsorption properties and extensive porous structure. Activated charcoal particles have a very large surface area with large pore structures. This surface area provides more area to interact with substances that cause plaque and stains on teeth. Activated charcoal has a high adsorption capacity
Analysis of the Chemical Content of Jamblang Bark (Syzygium cumin (L) Skeels) Using Gas Chromatography-Mass Spectrometry and Fourier Transform Infrared
Jamblang plant (Syzygium cumini (L.) Skeels) is a plant that has the potential as anticancer, antioxidant, anti-inflammatory, anti-allergic, antibacterial, hepatoprotective, gastroprotective, cardioprotective, antidiabetic, antihyperlipidemic. Jamblang plants contain chemical compounds of alkaloids, flavonoids, resins, tannins, and essential oils. This study aimed to identify the class of flavonoid compounds contained in jamblang leaf isolates using gas chromatography-mass spectrometry and Fourier transform infrared. The results of the identification of jamblang leaves showed that the isolate contained flavonoid compounds, the flavonol group, which also had 69 potential bioactive compounds
Pharmacological Activity of Betulinic Acid: A Systematic Literature Review
Betulinic acid comes from betulin, a triterpenoid compound that naturally occurs in the bark of the Betula tree. Betulin has a pentacyclic chemical structure, which contains five distinct rings. Betulinic acid is the carboxylic acid form of betulin, meaning it has a carboxyl group (-COOH), which gives this compound its acidic nature. This study is a literature review. Data obtained from journal analysis in the form of qualitative and quantitative data. In this review article, the authors have explored in depth the promising pharmacological activities of betulinic acid. The studies that have been carried out consistently prove the potency of this compound in various therapeutic and pharmacological aspects. Research has also identified the ability of this compound to modulate biochemical pathways relevant to the nervous system, providing new hope in the treatment of complex neurological disorders