Eureka Herba Indonesia (EHI - E-Journal)
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Effectiveness of Cold Cabbage Leaf Compress (Brassica Oleracea Var. Capitata) To Reduce Breast Swelling of Breastfeeding Mothers in Purwakarta Regency, Indonesia
Full text linkBreast engorgement is one of the problems often experienced by breastfeeding mothers. Breast engorgement can cause pain and discomfort and can even inhibit breast milk production. Cold cabbage leaves (Brassica oleracea var. capitata) are a traditional treatment that has long been used to reduce breast swelling. This study aims to determine the effectiveness of cold cabbage leaves in reducing breast swelling in breastfeeding mothers in Purwakarta Regency, Indonesia. This research uses a quasi-experimental design with a pre-post-test approach. The research sample was 60 breastfeeding mothers in Purwakarta Regency, Indonesia. The mothers were divided into two groups, namely the intervention group, who were given cold cabbage leaf compresses, and the control group, who were not given cold cabbage leaf compresses. Breast swelling is measured using the visual analog scale (VAS) pain scale. Measurements were taken on the first day and 7th day after intervention. The results showed that there was a significant difference between the intervention group and the control group in terms of reducing breast swelling. On day 7, the VAS value in the intervention group (3.2 ± 0.5) was lower than the control group (5.5 ± 0.7). Cold cabbage leaf compress is an effective natural way to reduce breast swelling in breastfeeding mothers
Analysis of Total Phenolic Content in Jamblang Fruit Seeds (Syzygium cumini): A Systematic Literature Review
Full text linkJamblang seeds contain various bioactive compounds, one of which is phenolic. Phenolic compounds are known to have strong antioxidant activity, which can help protect the body from free radicals and oxidative stress. Free radicals are unstable molecules that can damage body cells and tissues, thereby contributing to various chronic diseases such as cancer, diabetes, and heart disease. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the analysis of total phenolic content in jamblang fruit seeds (Syzygium cumini). This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. The total phenolic content of jamblang fruit seeds ranges from 100-500 mg/g. The highest total phenolic content was found in jamblang fruit seeds originating from Bogor, namely 476.18 mg/g. Jamblang fruit seeds contain quite high levels of phenolic compounds. The total phenolic content of jamblang fruit seeds can vary depending on the growing location, variety, and extraction method used
Potential of Ethanol Extract of Red Gedi Leaves (Abelmoschus manihot L. Medik) Against Endogenous Antioxidant Activity in Rat Model of Diabetes Mellitus
Full text linkDiabetes mellitus (DM) is characterized by chronic hyperglycemia and increased oxidative stress, contributing to disease complications. Red gedi leaves (Abelmoschus manihot L. Medik) are rich in bioactive compounds, including tannins, saponins, alkaloids and flavonoids, with antioxidant potential. This study aims to evaluate the effect of ethanol extract of red gedi leaves on endogenous antioxidant activity in rat model of DM induced by STZ-NA. Male rats were induced with DM with streptozotocin (STZ)-NA. Rats were divided into five groups: normal control (KN), DM control (KDM), glibenclamide positive control (KPG), and group treated with red gedi leaf extract at a dose of 100 mg/kgBW (GEDI 100), 200 mg/kgBW (GEDI 200), and 400 mg/kgBW (GEDI 400). The parameters observed included blood glucose levels, malondialdehyde (MDA) as a marker of oxidative stress, as well as the activity of the antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in liver tissue. Data analysis used one-way ANOVA and Tukey's post hoc test (p<0.05). The results showed that the yield of ethanol extract from red gedi leaves was 6.984%. Administration of red gedi leaf extract at a dose of 400 mg/kgBW (GEDI 400) significantly reduced blood glucose levels (p<0.05) and MDA (p<0.05), and increased the activity of SOD (p<0.05), CAT (p<0.05), and GPx (p<0.05) in DM rats compared to the DM control group (KDM). The effect of GEDI 400 was comparable to the effect of glibenclamide as a positive control. The ethanol extract of red gedi leaves at a dose of 400 mg/kgBW was effective in increasing endogenous antioxidant activity and reducing oxidative stress in STZ-NA-induced DM rats, showing potential as an antioxidant and antidiabetic agent
The Hematopoietic Potential of Tamarillo (Cyphomandra betacea) and Pitaya (Hylocereus spp.) Juices in Anemia Management: A Randomized Controlled Trial in Bukittinggi, West Sumatra, Indonesia
Full text linkAnemia is a global health concern, particularly prevalent in developing countries. Traditional remedies like tamarillo and pitaya have been suggested to boost blood production. This study aimed to evaluate the efficacy and safety of these juices in managing anemia. A randomized, double-blind, placebo-controlled trial was conducted in Bukittinggi, West Sumatra, Indonesia. Participants with mild to moderate anemia (hemoglobin 8-11 g/dL) were randomized to receive daily tamarillo juice, pitaya juice, or a placebo for 12 weeks. Hemoglobin, hematocrit, iron levels, and hematological parameters were assessed at baseline and week 12. A total of 150 participants completed the study (50 per group). Both tamarillo and pitaya juice groups showed significant increases in hemoglobin and hematocrit levels compared to the placebo group (p < 0.05). Pitaya juice also demonstrated a significant increase in iron levels (p < 0.01). No serious adverse events were reported. Tamarillo and pitaya juices show promise as adjunctive therapies for anemia management. Further research is needed to explore their long-term effects and mechanisms of action
Analysis of Ethnopharmacological Studies on the Use of the Sambiloto Plant in the Treatment of Malaria in the Asmat Tribal Community in Papua, Indonesia
Full text linkMalaria is still a major health problem in Indonesia, especially in the Papua region. The Asmat tribe has traditional knowledge about the use of medicinal plants to treat malaria, one of which is sambiloto. This research uses a qualitative observational research design with an ethnopharmacological approach. This approach combines aspects of ethnography and pharmacology to study traditional knowledge and the use of medicinal plants in a community. It was discovered that sambiloto has long been used by the Asmat tribe to treat malaria. Sambiloto leaf is processed into a decoction or juice and drunk to relieve malaria symptoms such as fever, chills, and headaches. This ethnopharmacological study shows that sambiloto has potential as an herbal medicine for treating malaria in the Asmat community. Further research is needed to test the effectiveness and safety of sambiloto in the treatment of malaria
Bay Leaf Extract as a Potential Therapeutic Agent for LDL Reduction in Hypercholesterolemia: A Dose-Response Study
Full text linkHypercholesterolemia, characterized by elevated low-density lipoprotein (LDL) cholesterol levels, is a major risk factor for cardiovascular disease. The current study investigated the dose-dependent effects of bay leaf extract on LDL cholesterol reduction in a hypercholesterolemic rat model. Male Wistar rats were fed a high-fat diet to induce hypercholesterolemia. They were then randomly assigned to five groups: positive control (simvastatin), negative control (standard diet), and three treatment groups receiving graded doses of bay leaf extract (0.72 g, 1.08 g, and 1.80 g). LDL cholesterol levels were measured after seven days of treatment. Bay leaf extract administration resulted in a dose-dependent reduction in LDL cholesterol levels. The highest dose (1.80 g) exhibited comparable efficacy to simvastatin in lowering LDL cholesterol. In conclusion, bay leaf extract demonstrates potential as a therapeutic agent for managing hypercholesterolemia by effectively reducing LDL cholesterol levels. The optimal dose for LDL reduction appears to be 1.80 g. Further research is warranted to explore the underlying mechanisms and clinical implications of these findings
The Effect of Ginger Compress on Back Pain in Pregnant Women in the Work Area of X Health Center, Cianjur Regency, Indonesia
Full text linkBack pain is one of the disorders often experienced by pregnant women. The research results show that the prevalence of back pain in pregnant women in Indonesia reaches 60-80%. One non-pharmacological therapy that can be used to treat back pain in pregnant women is a ginger compress. This study aims to determine the effect of ginger compresses on back pain in third-trimester pregnant women in the working area of X Health Center, Cianjur Regency, Indonesia. This study used a quasi-experimental design with a two-group pretest-posttest design. The research population was pregnant women in the third trimester who experienced back pain. The sample size was 60 people, who were divided into two groups, namely the intervention group (30 people) and the control group (30 people). The intervention group was given a ginger compress for 15 minutes, 3 times a day, for 3 days. The control group was given warm water compresses for 15 minutes, 3 times a day, for 3 days. The results of the study showed that the average value of back pain in the intervention group before the intervention was 4.68 (moderate pain scale) and after the intervention was 2.91 (mild pain scale). The average value of back pain in the control group before the intervention was 4.75 (moderate pain scale), and after the intervention, it was 3.88 (moderate pain scale). The Wilcoxon test showed that ginger compresses reduced back pain in third-trimester pregnant women (p=0.000). The conclusion of this study is that ginger compresses have an effect on reducing back pain in third-trimester pregnant women
Traditional Therapy in Postpartum Care: A Qualitative Study in Neniari Village, Manggarai Regency, East Nusa Tenggara
Full text linkThe postpartum period is an important period for mothers to recover their physical and psychological condition after giving birth. In Indonesia, there are various traditional practices carried out to care for postpartum mothers. This research aims to explore traditional therapeutic practices in postpartum care in Neniari Village, Manggarai Regency, East Nusa Tenggara. This research uses a qualitative study method with a phenomenological approach. Data was collected through in-depth interviews with 10 postpartum mothers and 3 traditional birth attendants. The research results show that there are three types of traditional therapy that are commonly practiced in Neniari Village, namely: Herbal concoctions: Herbal concoctions are used to treat various complaints experienced by postpartum mothers, such as bleeding, abdominal pain and breast swelling. Ukup: Ukup is a massage technique performed to improve blood circulation, reduce pain, and improve mood. Rahu: Rahu is a steaming technique performed to warm the body, tone the uterine muscles and increase breast milk production. The research results show that traditional therapy has many benefits for postpartum mothers, both physically and psychologically. Traditional therapy can also be an alternative postpartum care that is affordable and easy to obtain
Conservation and Exploration of the Potential of Rare Medicinal Plants in the Tropical Rainforest of Bukit Barisan, Sumatra, Indonesia: An Effort Towards Sustainable Herbal Medicine
Full text linkThe Bukit Barisan tropical rainforest in Sumatra, Indonesia, is one of the most biodiverse areas in the world. It is estimated that there are more than 10,000 plant species in this forest, and many of them have potential as herbal medicines. However, deforestation and overexploitation threaten the preservation of medicinal plants in the Bukit Barisan tropical rainforest. This causes loss of valuable natural resources and hinders research and development of new herbal medicines. This research was conducted in several tropical rainforests in Bukit Barisan, Sumatra. Field surveys were conducted to document rare medicinal plant species. Plant samples were collected and analyzed for their phytochemical content. Bioassay tests were carried out to evaluate antibacterial, antioxidant and anti-inflammatory activities. Strategies for conservation and sustainable exploration of rare medicinal plants are developed based on research results. Field surveys found 27 species of rare medicinal plants. Phytochemical analysis shows that this plant contains various bioactive compounds, such as alkaloids, flavonoids and terpenoids. Bioassay tests show that this plant has significant antibacterial, antioxidant and anti-inflammatory activity. In conclusion, the Bukit Barisan tropical rainforest has great potential for the development of herbal medicine. Sustainable conservation and exploration of rare medicinal plants in the Bukit Barisan tropical rainforest is important to ensure the preservation of these valuable natural resources and to improve community health
Analysis of Compound Content of Ethanol Extract of Butterfly Pea Flower (Clitoria ternatea L.) Using Thin Layer Chromatography Method: A Systematic Literature Review
Full text linkThe butterfly flower (Clitoria ternatea L.) is an herbal plant that is widely used in traditional medicine in Indonesia. The chemical compounds in butterfly pea flowers are thought to have various biological activities, such as antioxidant, anti-inflammatory, antibacterial and antidiabetic. Analysis of the compound content in butterfly pea flower extract can be done using various methods, one of which is thin layer chromatography (TLC). The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) analysis of the compound content of ethanol extract of butterfly pea flowers using the thin layer chromatography method. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. The ethanol extract of butterfly pea flowers contains various groups of secondary metabolite compounds, such as flavonoids, saponins, terpenoids and tannins. These compounds are thought to have various biological activities, such as antioxidant, anti-inflammatory, antibacterial and antidiabetic