Online Journal Faculty of Medicine Universitas Sriwijaya
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Prevalensi Kejadian Penyakit Menular Seksual (HIV, Hepatitis B, Hepatitis C, dan Sifilis) pada Wanita Penjaja Seks di Palembang
No full textData Centers for Disease Control and Prevention (CDC) tahun 2016 menunjukkan sekitar 110 juta orang menderita penyakit menular seksual (PMS). PMS sering kali dipandang sebelah mata, padahal dampaknya bagi kesehatan jangka panjang cukup signifikan terutama pada wanita dan bayi, seperti infertilitas, kelainan kongenital, kanker dan lain-lain. Penjaja seksual merupakan kelompok berisiko tinggi untuk tertular PMS. Karena itu, perlu diketahui prevalensi PMS terutama pada mereka yang berisiko tinggi (wanita penjaja seksual) sehingga dapat dibuat kebijakan terkait program pengendalian dan pencegahan PMS. Jenis penelitian yang digunakan adalah studi prevalensi dengan pendekatan survai klinis secara cross sectional. PMS yang dihitung prevalensinya pada penelitian ini adalah infeksi HIV, Hepatitis B, Hepatitis C dan sifilis. Serum dari subjek penelitian dikumpulkan dan diperiksa anti-HIV untuk infeksi HIV, anti-HCV untuk Hepatitis C, HbsAg untuk Hepatitis B dan VDRL untuk sifilis. Didapatkan prevalensi PMS pada wanita penjaja seksual di Palembang adalah sebagai berikut yaitu: HIV sebesar 4.9%, sifilis sebesar 3.3%, Hepatitis B sebesar 9.8% dan Hepatitis C sebesar 1.6%. Edukasi, sosialisasi terkait bahaya dan dampak dari PMS perlu dilakukan terutama pada mereka yang berisiko tinggi seperti pada wanita penjaja seksual sebagai bentuk dari program pengendalian dan pencegahan PMS
Stabilisasi dan Transportasi Neonatus
No full textApproximately 10 percent of newborns will require some level assistance with breathing, and a few (<1 percent) will require resuscitation in the birthing room. After resuscitation, many of these newborns require acute transport to a different facility. Stabilisation prior to transport is essential and the principles of neonatal transportation are independent of distance. Hypothermia and hypoglycaemia should be prevented in neonates during transport as they adversely affect the outcome. This article provides an overview of principles from the STABLE Program, which guides clinicians in providing postresuscitation care and pretransport and during transport stabilization for compromised newborns
Rasionalitas Penggunaan Antibiotik Ciprofloxacin pada Penderita Demam tifoid
No full textPenyakit demam tifoid (Typhoid fever) merupakan penyakit yang disebabkan oleh bakteri Salmonella typhiterutama menyerang bagian saluran pencernaan. Pengobatan terhadap penyakit demam tifoid terus berkembang.Antibiotik golongan fluoroquinolone (ciprofloxacin, ofloxacin, dan pefloxacin) merupakan terapi yang efektif untukdemam tifoid yang disebabkan isolate tidak resistensi terhadap fluoroquinolone dengan angka kesembuhan klinissebesar 98%, waktu penurunan demam 4 hari. Tujuan penelitian ini adalah untuk mengetahui usia, jenis kelamin,dosis, lama pemberian, frekuensi pemberian dan interaksi obat lainnya. Penelitian ini adalah penelitian deskritifberupa studi penggunaan obat dengan menggunakan data sekunder berupa rekam medik di Instalasi PenyakitDalam RSUD Kayuagung dan RSMH Palembang. Penelitian ini dilakukan pada bulan November – Desember 2014dan dilakukan di Instalasi Rawat Inap Bagian Penyakit Dalam RSUD Kayuagung dan RSMH Palembang. Terdapat 7pasien demam tifoid di RSMH Palembang dan 23 pasien di RSUD Kayuagung yang diterapi dengan ciprofloxacin.Usia 20–40 tahun merupakan kelompok usia dengan frekuensi tertinggi 19 orang (63,3%). Penderita laki-laki 15orang (50%) dan perempuan 15 orang (50%). Dosis 500 mg adalah dosis terbanyak yang diberikan denganfrekuensi pemberian 2x sehari dan lama pemakaian selama 14 hari. Terdapat sebanyak 26 (86.6%) pemakaianbersifat antagonis. Hasil rekam medik yang diteliti telah tepat indikasi, dosis, dan frekuensi pemberian. Tetapimasih ada interaksi obat antara obat satu dengan yang lainnya, serta pemberian obat yang over prescribing
Risk Factor Analysis which Affect Severity of Low Back Pain to ward The Patients of Medic Rehabilitasion Intsalasi in RSUP dr. Mohammad Hoesin Palembang in 2016-2017.
No full textThe incidence of lower back pain in the productive age population continues to increase. Various risk factors such as age, sex, smoking, and physical activity, length of work and work position can exacerbate lower back pain complaints. This study was conducted to analyze risk factors that affect the severity of low back pain in patients who perform therapy in Medical Rehabilitation Installation RSUP dr. Mohammad Hoesin Palembang period 2016-2017. The research used is analytical observation with cross-sectional technique. The sample of research is 71 respondents in Medical Rehabilitation Installation of dr. Mohammad Hoesin Palembang that meets the inclusion criteria. The data was further processed and grouped in table form. At 71 respondents found 49 respondents suffered severe NPB and 22 respondents suffered from mild NPB. The results showed that sex, physical activity, work position and duration of work had significant relationship with mild cases of low back pain (p = 0,03, p = 0,000, p = 0,00, p = 0,002). While age, smoking, BMI did not have a significant association with mild cases of low back pain (p = 0.08, p = 1.044, p = 0.690). Risk factors that affect the severity of lower back pain are male, physical weight, working position sitting or bending and length of work more than 7 hours per day
Effects of Moringa Leaf Extract (Moringaoleifera) in the Breastfeeding: Efek Pemberian Ekstrak Daun Kelor (Moringaoleifera) dalam Proses Menyusui
No full textExclusive breastfeeding for 6 months is a global strategies to promote the growth, development, health and survival of infants. Despite the many benefits of exclusive breastfeeding for infants, mothers, families and communities, the coverage is still low in many countries including Indonesia. Mother's milk is produced from the collaboration between mechanical stimulation of hormonal and nerve factors. One of the hormones that affects is the estrogen. The hormone estrogen is a sex hormone produced by the uterus to stimulate the growth of sex organs such as breasts and pubic hair and regulate the menstrual cycle. The hormone estrogen also plays a role to maintain the texture and function of the breast. Pregnancy in a woman, making the breast gland will be more developed by the influence of estrogen, somatomamotropin and prolactin hormones. The process is affected by the hormones estrogen and progesterone. Estrogen significantly stimulates the synthesis and release of pituitary hormone, this effect depends on the duration and dose of administration. In Indonesia, moringa plant is a local food that has the potential to be developed in culinary breastfeeding mothers because it contains phytosterol compounds that function to improve and facilitate the production of breast milk (laktogogum effect). This paper will discuss some of the facts about the effect of Moringaoleifera extract on prolactin levels in increasing the quantity and quality of breast milk in the breastfeeding process. The amount of nutrients in the Moringa leaf (Moringaoleifera) one such as phytosterol compounds (laktogogum effect) in increasing levels of pituitary hormone and iron hormones can have a positive impact on the health of the baby because breast milk is the most important and best natural baby food
Biomolecular Characteristics of Amyloid Precursor Protein Mutations As Causes of Alzheimer's Disease Analyzed Through Bioinformatics Media: Biomolecular Characteristics of Amyloid Precursor Protein Mutations As Causes of Alzheimer's Disease Analyzed Through Bioinformatics Media
No full textMethods of biomolecular analysis on protein through bioinformatics media has been growing rapidly. This report is intended to describe the results of biomolecular amyloid precursor protein (APP) analysis and the characteristic change of APP mutations causing cognitive degeneration disorder through bioinformatics media and search to reliable biomolecular sites. APP is a transmembrane protein that is widely present in neuronal tissue. APP plays an important role for the formation of neuronal cells. The APP gene is located on the 21st chromosome that has 290,586 base pairs (bp) of 20 exons and 19 introns. In the form of a protein, APP consists of 770 amino acids with major expressions located on the cell surface. Mutation of APP genes is believed to play a role in the incidence of Alzheimer's disease. One of the mutations studied in this paper is the mutation of Alanin to Glysin at the position of the 692 amino acid (APP mutant A692G). This mutation affects the impairment of cerebral amyloid angiopathy belonging to the Alzheimer Disease Familial-1 group.These mutations do not cause changes in predictions of secondary structures and only cause slight changes in molecular weight, amino acid composition, atomic composition, aliphatic index, hydroplasticity and stability index. APP A692G mutation does not alter topology, hydrophobicity, cutting prediction and protein location prediction. Mutation also removes only the side chains at the position of the mutated amino acids
Relation Between Knowledge, Attitudes and Behavior Against Self Medication Use of Over The Counter Analgesic at STIK Bina Husada: Hubungan Pengetahuan, Sikap dan Perilaku Terhadap Self Medication Penggunaan Obat Analgesik Bebas di Sekolah Tinggi Ilmu Kesehatan Bina Husada
No full textNyeri adalah pengalaman perasaan emosional yang tidak menyenangkan akibat terjadinya kerusakan aktual maupun potensial, dan juga boleh menyebabkan terjadinya kerusakan. Pengobatan yang sering dilakukan untuk meringankan nyeri ini adalah dengan tindakan pengobatan sendiri atau self medication salah satunya dengan konsumsi obat analgesik, Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan, sikap dan perilaku terhadap self medication penggunaan obat analgetik bebas di Sekolah Tinggi Ilmu Kesehatan Bina Husada
Jenis penelitian ini adalah observasional dalam bentuk cross sectional. Sampel penelitian ini adalah mahasiswa Sekolah Tinggi Ilmu Kesehatan Bina Husada yang memenuhi kriteria inklusi dan kriteria eksklusi. Jumlah sampel dalam penelitian ini adalah 400 orang. Cara pengambailan distratifikasi berdasarkan semester yang diambil secara random sederhana dan secara proporsional dari setiap semester. Data dianalisa dengan menghitung OR dan menggunakan Chi Square Tes
Hasil penelitian Didapatkan ada hubungan (OR 1,160) dan tidak bermakna (P-value 0,773) antara pengetahuan terhadap self medication penggunaan obat analgesik, ada hubungan (OR 1,542) dan tidak bermakna (P value 0,212) antara sikap terhadap Terhadap Self MedicationPenggunaan Obat Analgesik bebas, ada hubungan (OR 2,528) dan bermakna (p- value 0,014) antara perilaku terhadap Self medication penggunaan obat Analgesik Bebas, didapatkan faktor yang berperan terhadap penggunaan obat yaitu perilaku dengan OR 0,417 dan bermakna (p=0,020)
Influence of Fe tablets to Increase Hemoglobin Levels of TB Patients in District of Seberang Ulu I Palembang City: Pengaruh Pemberian Tablet Fe Terhadap Peningkatan Kadar Hemoglobin Pasien TB di Kecamatan Seberang Ulu I Kota Palembang
No full textPeople with active pulmonary TB are often macronutrient deficiencies, weight loss and decreased appetite. TB patients are susceptible to anemia, with Fe tablets given is able to cure low TB hemoglobin levels. The method of this study was conducted with the design of Quasi Experimental study. The population was tuberculosis patients in Seberang Ulu I District, with 25 sample of positive TB patients. Samples were given Fe tablet for 90 days. The results of this study were given Fe tablet tablets that affected significant hemoglobin levels (P <0.002) between patients before was before and after tablets were given. The increment of hemoglobin levels of patients before and after the end of tablet given of TB patients was 1.16 g / dl. Suggestions that can be given is the need to be given Fe tablets in TB patients to improve nutritional status so that treatment can achieve optimal results
Comparative Effectiveness of Papaya Leaf Stew (Carica Papaya Linn) With Turmeric Acid (Curcuma Domestica Val-Tamarindus Indica) Against Primary Dysmenorrhea: Perbandingan Efektifitas Rebusan Daun Pepaya (Carica Pepaya Linn) Dengan Kunyit Asam (Curcuma Domestica Val-Tamarindus Indica) Terhadap Dismenore Primer
No full textYoung women often feel primary dysmenorrhoea because the hormonal cycles experienced are not stable, this can disrupt the concentration and activity of young women. The principle of back to nature is increasingly popular today, the side effects of chemical drugs can cause new problems, it is one of the driving force of the development of traditional medicine. Papaya leaves contain Vitamin E which can reduce dysmenorrhea. In addition, turmeric acids also contain curcumine and anthocyanins that inhibit cyclooxygenase, thereby reducing the occurrence of inflammation during uterine contractions. The aim of this research is to know the effectiveness of papaya leaf stew with acidic turmeric to primary dysmenorrhea. Type of Research is an experimental study with a Pretest-Posttest Control Group Design design. The sample is 30 people. The research was conducted on December 27, 2017 s.d February 24, 2018 at SMP Negeri 46 Palembang. Instrument to measure pain Numeric Rating Scale. The statistical test used by Wilcoxon and Mann Whitney U. Average score of pain before papaya leaves stem 5.40 ± 0.73 while the mean score of pain after given turmeric acid 5.33 ± 0.61 The mean score of pain after being given papaya leaves stew 3.60 ± 0.91 while the mean score of pain after given turmeric acid 4.06 ± 0.79. There was a difference of mean score of dysmenorrhea pain before and after given papaya leaf stem p value = 0.000. There is difference of mean score of dysmenorrhea pain before and after given turmeric acid p value = 0,002. There was no difference of mean score of dysmenorrhea pain before and after given papaya leaf sting and turmeric acid p value = 0,217. The decoction of papaya leaf and turmeric acid have the same effectiveness in reducing primary dysmenorrhea pain
Pengaruh Wet Cupping terhadap Kadar Hemoglobin Darah Vena Orang Sehat
No full textWet cupping known as blood letting in western countries has long been done since the Hippocrates. Hijamah or cupping (other languages, coke, cupping, cupping) is a therapy that aims to cleanse the body of blood which contains toxic with thin slices or small punctures on the surface of the skin, Wet Cupping is developed as an alternative and complementary treatment, the purpose of the study is to determine the effect of wet cupping against healthy blood vein hemoglobin levels. This research method with experimental clinical test with pre and post intervention design without control group. The implementation of wet cupping is carried out at Puskesmas Palembang Campus and blood collection and blood tests at the Health Laboratory Center (BBLK) of South Sumatra Province. The sample of this study was 30 respondents with an age range of 18-22 years, the parameters seen were the value of hemoglobin levels, the treatment was carried out after 8 hours of intervention. To control confounding factors in this study, respondents before getting treatment were not allowed to exercise and heavy activities and still consume daily food without additional food. The results of the study showed a significant increase in hemoglobin levels, 8 hours after wet cupping was performed on healthy venous blood, the mean hemoglobin level was 15.08 ± 0.63, increasing to 15.45 ± 0.76. The conclusion that wet cupping affects healthy people's venous blood hemoglobin levels, it is hoped that wet cupping can be used in alternative and complementary therapies