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Serum myeloperoxidase, paraoxonase, and plasma asprosin concentrations in patients with acute myocardial infarction
Full text linkIntroduction: The objective of this study was to evaluate the usefulness of the serum biomarkers myeloperoxidase (MPO), paraoxonase (PON), and plasma asprosin in acute myocardial infarction (AMI) diagnosis and assess their compatibility with routinely screened cardiac biomarkers. Methods: This study was conducted using a prospective cross-sectional design and included 90 patients, consisting of 60 patients diagnosed with AMI (30 with ST-segment elevation and 30 with non-ST-segment elevation on ECG) and 30 controls (without a diagnosis of AMI). Changes in the levels of cardiac biomarkers (Hs-cTnI, CK, CK-MB), lipid profile (TC, TG, LDL, HDL), MPO, PON, asprosin, and routine biochemical parameters of patients were evaluated. Furthermore, receiver operating characteristic curve analysis revealed the diagnostic value of Hs-cTnI, MPO, PON, and asprosin in predicting AMI. Binary logistic regression analysis of cardiac marker concentrations was used to predict the presence of AMI. In contrast, multinomial logistic regression analysis was conducted to predict the type of AMI and the control group. Results: The median levels of MPO and plasma asprosin were found to be higher in the patient group (3.22 [interquartile range {IQR}: 2.4-4.4] ng/ml and 10.84 [IQR: 8.8-17.8] ng/ml, respectively) than in the control group (2.49 [IQR: 1.9-2.9] ng/ml and 4.82 [IQR: 4.6-8.0] ng/ ml, respectively) (p = 0.001 and p < 0.001, respectively). The median levels of PON were 8.94 (IQR: 7.6-10.4) ng/ml in the patient group and 10.44 (IQR: 9.1-20.0) ng/ml in the control group (p < 0.001). In the binary logistic regression model, compared with the control group, a 1 ng/ml increase in MPO level increased the odds of having AMI by 3.61 (p = 0.041, 95% CI: 1.055-12.397), whereas a 1 ng/ml increase in asprosin level increased the odds of having AMI by 2.33 (p < 0.001, 95% CI: 1.479-3.683). In the multinominal logistic regression model, compared with the control group, a 1 ng/ml increase in the MPO level increased the odds of having NSTEMI by 4.14 (p = 0.025, 95% CI: 1.195-14.350), whereas a 1 ng/ml increase in asprosin concentrations increased the odds of having NSTEMI by 2.35 (p < 0.001, 95% CI: 1.494-3.721). Conclusion: Herein, MPO and asprosin concentrations increased with Hs-cTnI, and a decrease in PON concentration indicated that oxidant-antioxidant parameters and adipokines were related to AMI pathogenesis.Scientific Research Projects Coordinatorship of Kafkas University,Turkey [2021-TS-09]This study was financially supported by the Scientific Research Projects Coordinatorship of Kafkas University,Turkey, under the project number 2021-TS-09
RADIOLOGICAL ASSESSMENT OF THE PREVALENCE AND LOCATION OF ROOT RESORPTION IN EPILEPTIC PATIENTS: AN OBSERVATIONAL STUDY
Full text linkObjective Antiepileptic drugs used in the treatment of epilepsy patients have a negative effect on bone tissue, but as far as we know, tooth root resorption has not been investigated in these patients. The aim of this study was to evaluate the prevalence of external and internal root resorption and its distribution according to resorption sites in epilepsy patients using antiepileptic drugs. Material and Method Panoramic radiographs obtained before dental treatment were evaluated. While the case group consisted of only those with epilepsy, the control group included healthy subjects. The presence/absence of external and internal resorption of all teeth (except the third molars), region of resorption (cervical, middle, and apical region of the root), age, and sex were recorded in an excel file. Independent sample t-test or Mann- Whitney U test according to normality of distribution and a chi-square test to compare categorical variables were used. Results The resorption in 93 (21.9%) of 424 patients (236 healthy subjects and 188 epileptic patients), the groups did not significantly differ by the presence of external and internal resorption (p = 0.089 and 0.746). It was more common in those over 30 years and males (p = 0.018 and 0.013). Conclusion We concluded that the presence of resorption in epilepsy patients was not different from healthy subjects. However, in patients with epilepsy, resorption was mostly seen in the lower molars and middle 1/3 regions. Clinicians should consider our results when treating these patients
Investigation of the effects of core exercises applied to 12-14 age group football players on bio-banding on selected motor parameters
Full text linkSosyal Bilimler Enstitüsü, Beden Eğitimi ve Spor Ana Bilim DalıGelişen teknoloji ile yeni antrenman metotları ve yeni sınıflandırma yöntemleri geliştirilmektedir. Bu sınıflandırmalardan biri de biyo-gruplamadır. Biyo-gruplama, çocukların kronolojik yaşlarından ziyade iskelet olgunluklarına göre gruplandığı bir yöntem olarak kabul edilir. Olgunluk düzeyi, çocuklarda sportif performansın optimum seviyede uygulanmasını etkilediği bilinmektedir. Bu bilgiler ışığında çalışmanın amacı 12-14 yaş grubu futbolculara biyo-gruplamaya göre uygulanan core egzersizlerinin seçili motor parametrelere etkisinin incelenmesidir. Çalışmaya Niğde Anadolu Futbol Kulübü bünyesinde antrene olan 90 erkek futbolcu katılmıştır. Futbolculara biyo-gruplama yapılarak, erken ergenlik (30 kişi deney grubu), ergenlik dönemi (30 kişi kontrol grubu), geç ergenlik (30 kişi kontrol grubu) isimli deney ve kontrol grupları oluşturulmuştur. Deney grubuna, rutin futbol antrenmanlarına ek olarak haftada 3gün 8 hafta süre ile dinamik core egzersizleri uygulanırken, kontrol grubu rutin antrenmanlarına devam etmiştir. Çalışmanın gerçekleştiği 8 haftalık periyotta, çalışmanın başlangıcında ve sonunda futbolculardan dikey sıçrama, çeviklik ve sürat performans ölçümleri alınmıştır. Futbolcuların dikey sıçrama performansları Fotosel bağlantılı mat Smartspeed ile çeviklik ve sürat performansları Smartspeed Fotosel ile ölçülmüştür. Verilerin analizinde SPSS 24 paket programı kullanılmıştır. Futbolcuların demografik değişkenlerinin aritmetik ortalama ve standart sapmaları hesaplanmıştır. Dikey sıçrama, çeviklik ve sürat performanslarının gruplar içi ön test ile son test karşılaştırılmasında Paired T Testi, gruplar arası ön testler ile son testlerin karşılaştırılmasında One Way Anova Testi, farkın lehine belirlenmesinde ise Tukey Testi kullanılmıştır. Yaş değişkenine göre grup içi karşılaştırmalarda anlamlı fark olduğu, farkın son testler lehine olduğu tespit edilmiştir. Grup içi karşılaştırmada en fazla gelişimin deney grubunda olduğu tespit edilmiştir. Biyo-gruplamaya göre gruplar arası karşılaştırmalarda sürat değişkeninde anlamlı fark olduğu ve farkın geç ergenlik lehine olduğu tespit edilmiştir. Sonuç olarak, biyo-gruplama yöntemi ile belirlenen gruplara uygulanan core egzersizlerinin seçili motor parametrelere olumlu etki ettiği ve aynı yaş içerisinde farklı olgunlaşma düzeyine sahip futbolculara uygulanacak core egzersizleri ile olgunlaşmadan doğan motor performans farkının kapatılmasında faydalı olacağı düşünülmektedir. Özellikle futbol branşı başta olmak üzere, diğer branşlarda da gruplandırmalar yapılırken yaş değişkenine ek olarak biyo-gruplamanın yapılması ve sporcuların kendi olgunluk seviyesine yakın sporcularla antrene olması, sporcuların performanslarını daha rahat göstermelerine katkı sağlayacağı düşünülmektedir.With the development of technology, new training methods and new classification methods are being developed. One of these classifications is bio-banding. Bio-Banding is considered a method in which children are grouped according to their skeletal maturity rather than their calendar age. It is known that maturity level affects the optimum level of sports performance in children. In light of this information, the aim of the study was to examine the effect of core exercises applied to 12-14 age group football players according to bio-grouping on selected motor parameters. 90 male football players who were training within Niğde Anadolu Football Club participated in the study. By bio-grouping the football players, experimental and control groups named early pubertal (30 people in the experimental group), pubertal (30 people in the control group), and late pubertal (30 people in the control group) were created. In addition to routine football training, dynamic core exercises were applied to the experimental group 3 days a week for 8 weeks, while the control group continued their routine training. During the 8-week period of the study, measurements of vertical jump, agility and speed performance measurements were taken from the football players at the beginning and end of the study. The vertical jump performances of the football players were measured using the Smartspeed mat with a photocell connection, and their agility and speed performances were measured using the Smartspeed Photocell. SPSS 24 package program was used to analyze the data. Arithmetic means and standard deviations of the demographic variables of the football players were calculated. Paired t-test was used to compare pretest and posttest within groups of vertical jump, agility and speed performances, one-way ANOVA test was used to compare pretests and posttests between groups, and Tukey's test was used to determine the difference in favor. It was determined that there was a significant difference in intra-group comparisons according to the age variable and that the difference favored the post-tests. In the intragroup comparison, it was determined that the greatest improvement was observed in the experimental group. In comparisons between groups according to bio-banding, it was determined that there was a significant difference in the speed variable and that the difference was in favor of late puberty. As a result, it is thought that core exercises applied to groups determined by the bio-banding method have a positive effect on selected motor parameters and that core exercises applied to football players with different maturation levels within the same age will be useful in closing the gap in motor performance arising from maturation. While groupings are made in other branches, especially in football, it is thought that bio-banding in addition to the age variable will contribute to the athletes' ability to perform more easily by training with athletes close to their own maturity level
Okul Öncesi Çocukların Öz Düzenleme Becerilerinin Ego Sağlamlık Düzeylerine Etkisinin İncelenmesi
Full text linkÖz düzenleme, yaşamın ilk yılarında kazanılması gereken temel bir beceridir; çocukluk, ergenlik ve yetişkinlik sürecinde olumlu ve olumsuz sonuçlara sebep olabilmektedir. Özellikle okul öncesi dönem, ego gelişiminde önemli bir süreçtir. Araştırmada öz düzenleme becerilerinin okul öncesi dönem çocuklarının ego sağlamlık düzeylerine etkisinin incelenmesi amaçlanmıştır. Ayrıca çalışmada çocukların öz düzenleme becerileri ve ego sağlamlık düzeyleri arasındaki ilişkiye bakılmıştır. Çalışma grubunu okul öncesine devam eden 5-6 yaş aralığındaki 309 çocuk ve anneleri oluşturmaktadır. Verilerin toplanmasında 4-6 Yaş Çocuklarına Yönelik Öz-Düzenleme Becerileri Ölçeği (Anne Formu) ve Çocuk Ego Sağlamlığı Ölçeği kullanılmıştır. Verilerin çözümlenmesi Pearson Korelasyon analizi ve CHAID analizi ile yapılmıştır. Sonuç olarak çocukların toplam öz düzenleme becerileri ve dikkat, çalışma belleği, engelleyici duygu, engelleyici davranış düzenleme ile ego sağlamlık düzeyleri arasında pozitif yönde anlamlı bir ilişki olduğu, çocukların öz düzenleme beceri düzeyleri arttıkça ego sağlamlık düzeylerinin de arttığı tespit edilmiştir. Araştırmada okul öncesi çocuklarında dikkat alt boyutunun çocukların ego sağlamlık düzeyleri üzerinde istatistiksel olarak manidar düzeyde birincil belirleyici etkiye sahip olduğu tespit edilmiştir. Ayrıca dikkati orta düzeyde olan çocuklardan engelleyici kontrol duygu davranışı yüksek olan çocukların ego sağlamlık düzeylerinin daha iyi olduğu tespit edilmiştir. Çocuklarda ego ve ego sağlamlığının desteklenmesi ve gelişimine önem verilmelidir. Araştırma sonuçları, çocukların ego dayanıklılığını geliştirmek için uygun müdahale adımları oluşturulmasına rehberlik edebilir
Employing pre-annealing as a control tool for alloying in CdSeTe/ CdTe stacks produced by evaporation in vacuum
Full text linkAlloying plays a critical role in CdSeTe/CdTe stacks used as absorber structure in high efficiency solar cells. In this study, the effect of pre-annealing between CdSeTe and CdTe on the structural and optical properties of stacks was examined in detail. After the CdSeTe layers (before CdTe) were grown by vacuum evaporation, pre-annealing was applied at moderate temperatures in the range of 200 degrees C-300 degrees C. According to both XRD patterns and Raman spectra, a clear effect of preannealing temperature on alloying ratios and phase formations between CdSeTe and CdTe was ascertained. It was observed from the surface images that the change in pre-annealing temperature affected the grain sizes and morphology, depending on the Se ratios in the alloying. It was found that the transmission spectrum shifted to the long wavelength region with the change in crystallization as a result of pre-annealing. In the PL spectra, the presence of transitions related to the phase structures revealed by the XRD results was detected. In consequence, pre-annealing at 250 degrees C presented more promising results for potential CdTe cell applications
Analyzing land use and climate change impacts of Suğla water storage in Turkey
Full text linkLarge water masses affect the land use of their surroundings and change the regional climate. Many methods are used to determine changes in regional climate and land use. This study aims to investigate the impact of the Su & gbreve;la water storage site in Turkey on land use and climate before and after 2006, the year the site became operational. The effects of the Su & gbreve;la water storage site on the climate and land use of the region were investigated using trend analyses, Autoregressive Integrated Moving Averages (ARIMA) models, and remote sensing techniques. For these purposes, increasing or decreasing trends in the meteorological time series covering the years 1960-2020 obtained from four meteorological stations in this region were determined by trend analysis. ARIMA models, a time series estimation and forecasting method, were used to make predictions for the next 10-year period (2020-2030) for meteorological data. With remote sensing techniques, changes in land use were determined using Landsat satellite images from 1984, 1990, 2000, 2006, 2010, 2020 and 2022. As a result of the study, increasing and decreasing trends were detected in trend analysis and ARIMA forecasts at all stations. It was observed that the water bodies have increased by 1% since 2006, when the site started to hold water, and there has been a significant increase from forest and semi-natural areas to agricultural areas. These results show that the land use around the Su & gbreve;la water storage area has changed significantly, with agricultural areas expanding
Insights into the high and prolonged inhibition mechanism of pyridoxine hydrochloride as vitamin B6: a new green inhibitor slowing the acidic corrosion of mild steel
Full text linkThis study aimed to assess the green corrosion inhibitor effect of the compound known as vitamin B6 and called pyridoxine hydrochloride (PYB6) on mild steel in 1.0 M HCl solution by some electrochemical techniques such as linear polarization resistance (LPR), potentiodynamic polarization, and electrochemical impedance spectroscopy (EIS) for various concentrations and durations. In order to examine the interplay between PYB6 and mild steel surface, various adsorption isotherms were tried and the best correlation constant among them was acquired by Langmuir adsorption isotherm. Experimental data calculated by the EIS method showed that the lowest inhibition efficiency value was 70.7% for 1.0 x 10-5 M PYB6 solution concentration after one hour of immersion, while the highest inhibition efficiency value was 96.8% for 1.0 x 10-3 M PYB6 solution concentration after 48 h of immersion. The finding of zero charge potential (PZC) of mild steel was found to be - 0.010 V in the solution containing the highest concentration of PYB6, which supports that the inhibition mechanism creates a protective film layer on the surface of mild steel with protonated PYB6 molecules. The surface analysis of PYB6 onto mild steel in a hydrochloric acid solution was also examined utilizing techniques such as atomic force microscope (AFM) and field emission scanning electron microscope (FE-SEM). It was concluded that PYB6 green inhibitor formed a presentative adsorption film on the surface of mild steel, effectively reducing its corrosion
The impact of school leadership on teachers' teaching practices: The mediatory role of teacher-professional collaboration and teacher self-efficacy (Evidence from TALIS 2018)
Full text linkEğitim Bilimleri Enstitüsü, Eğitim Bilimleri Ana Bilim Dalı, Eğitim Yönetimi Bilim DalıBu araştırmada, Türkiye'de okul liderliğinin öğretmenlerin öğretim uygulamaları üzerindeki etkisini öğretmen profesyonel iş birliği ve öğretmen özyeterliğinin aracı rolüyle incelemeyi amaçlanmıştır. Araştırma, TALIS 2018 çalışmasına katılan Türkiye'de ortaokul (ISCED 2) kademesinde görev yapan öğretmenlere ve okul müdürlerine uygulanan anketlerden elde edilen verilerden oluşan veri seti kullanılmaktadır. Türkiye'den ortaokul kademesinde 196 ortaokuldan 196 okul müdürü ile 3.952 öğretmen TALIS 2018 çalışması kapsamına alınmıştır. Öğretmen ve okula yönelik kullanılacak veri toplama araçları sırasıyla öğretmen (TTGINTT3) ve okul müdürlerine (PCGINTT3) uygulanan anketlerden elde edilmiştir. TALIS 2018 çalışmasında öğretmen-düzeyli değişkenlerden öğretim uygulamaları (T3TPRA) öğretmen özyeterliği (T3SELF) ve öğretmen profesyonel iş birliği (T3COLES) temel değişkenler olarak alınacakken, okul-düzeyli değişkenlerden ise yalnızca okul liderliği (T3PLEADS) dikkate alınmıştır. Araştırmada veri setinin analizinde, TALIS 2018 veri setindeki eksik veriler, varsayılan ayar olarak Mplus 8.3 kullanılarak gerçekleştirilen maximum likelihood estimators (FIML) uygulanarak ele alınmıştır Okul liderliği, öğretmen profesyonel iş birliği, öğretim uygulamaları ve özyeterlik arasındaki ilişkileri ortaya koymak için Pearson korelasyon katsayıları hesaplanmıştır. Ayrıca öğretmenlerin okullarda, okulların ilçelerde yer aldığı TALIS 2018 veri setinin hiyerarşik yapısı nedeniyle, çok düzeyli bir model olup olmadığına karar vermek için kümeleme ölçüsü olarak intraclass korelasyon katsayıları (ICC1 ve ICC2) hesaplanmıştır. Son olarak, araştırma, Mplus 8.3 kullanılarak sağlam maksimum olabilirlik tahmincisini yürüten tek seviyeli bir yapısal eşitlik modellemesi benimsenmiştir. Araştırma sonuçları, okul liderliğinin öğretmen profesyonel işbirliği ile pozitif yönde ancak küçük düzeyli bir ilişkiye sahip olduğunu göstermiştir. Ayrıca öğretmen profesyonel işbirliği ile öğretmen özyeterliği ve öğretmen öğretim uygulamaları arasında sırasıyla pozitif yönde ve orta ve küçük düzeyli anlamlı ilişkiler olduğu sonucuna ulaşılmıştır. Araştırmada öğretmen özyeterliği ile öğretmen öğretim uygulamaları arasında pozitif yönde ve orta düzeyli anlamlı bir ilişki; diğer taraftan da okul liderliğinin öğretmen özyeterliği üzerinde öğretmen profesyonel işbirliğinin aracılığıyla dolaylı bir etkiye sahip olduğu anlaşılmıştır. Son olarak, araştırma sonuçları okul liderliğinin öğretmen öğretim uygulamaları üzerinde öğretmen profesyonel işbirliği ve öğretmen özyeterliği aracılığıyla dolaylı bir etkiye sahip olduğunu ortaya koymuştur. Anahtar Kelimeler: Özyeterlik, Okul Liderliği (Öğretim liderliği), Profesyonel İşbirliğiThis study aimed to examine the impact of school leadership on teachers' teaching practices in Turkey through the mediating role of teacher professional collaboration and teacher self-efficacy. The research used a data set consisting of data obtained from surveys applied to teachers and school principals working at secondary school (ISCED 2) level in Turkey who participated in the TALIS 2018 study. 196 school principals and 3,952 teachers from 196 secondary schools in Turkey were included in the scope of the TALIS 2018 study. The data collection tools to be used for the teacher and the school were obtained from the surveys applied to the teachers (TTGINTT3) and school principals (PCGINTT3), respectively. In the TALIS 2018 study, teaching practices (T3TPRA), teacher self-efficacy (T3SELF) and teacher professional collaboration (T3COLES) were taken as the main variables among teacher-level variables, while only school leadership (T3PLEADS) was taken into account among school-level variables. In the analysis of the data set in the research, missing data in the TALIS 2018 data set were addressed by applying maximum likelihood estimators (FIML) using Mplus 8.3 as the default setting. Pearson correlation coefficients were calculated to reveal the relationships between school leadership, teacher professional collaboration, teaching practices and self-efficacy. In addition, due to the hierarchical structure of the TALIS 2018 data set, where teachers were located in schools and schools were located in districts, intraclass correlation coefficients (ICC1 and ICC2) were calculated as a clustering measure to decide whether there is a multi-level model. Finally, the research adopted a single-level structural equation modeling conducting robust maximum likelihood estimator using Mplus 8.3. Research results showed that school leadership had a positive but small relationship with teacher professional collaboration. Additionally, it was concluded that there were positive, medium and small-level significant relationships between teacher professional collaboration, teacher self-efficacy and teacher teaching practices, respectively. In the study, there was a positive and moderately significant relationship between teacher self-efficacy and teacher teaching practices; On the other hand, it was understood that school leadership has an indirect effect on teacher self-efficacy through teacher professional collaboration. Finally, research results revealed that school leadership has an indirect effect on teacher instructional practices through teacher professional collaboration and teacher self-efficacy. Keywords: Self-Efficacy, School leadership (Instructional leadership), Professional Collaboration
The effect of ionizing radiation on the fetal bone development in pregnant rats: Role of melatonin
Full text linkRadiation has been widely used in many business sectors over the last century. Our study investigated the possible teratogenic effects of radiation on the bones of rat fetuses and the protective effect of melatonin against these effects. In this study, 15 pregnant female Wistar albino rats were used. These rats were divided into four groups: the control group, melatonin group (10 mg/kg/day), radiation group (0.5 gray), radiation (0.5 gray) + melatonin group (10 mg/kg/day), and sham group (1 mm hanks/day). The skeletal system development of fetuses was examined with double skeletal and scanning electron microscope (SEM), histopathological methods. In our study, fetal weight, placental weight, and fetal morphometric values were found to be statistically significantly decreased in the radiation group compared to the control group (p < .05). In immunohistochemistry (IHC) analysis, alkaline phosphatase, and tartrate-resistant acid phosphatase) concentrations were found to be significantly lower in the radiation group compared to the other groups. In the SEM analysis, it was observed that the amount of calcium and sodium decreased when the radiation group was compared with the other groups. As a result, when exposed to ionizing radiation during pregnancy, melatonin has a protective feature against the negative effects of radiation on the bone development of fetuses.This research was the basis of Adem Tokpinaramp;apos;s PhD thesis. This study was approved by Erciyes University Animal Experiments Ethic Committee. The authors are grateful to the Erciyes University Clinical Research Center for their support.This research was the basis of Adem Tokpinar & apos;s PhD thesis. This study was approved by Erciyes University Animal Experiments Ethic Committee. The authors are grateful to the Erciyes University Clinical Research Center for their support
Objective Signs versus Subjective Disease Index in Dry Eye Disease
Full text linkObjective: To compare the ocular surface disease index (OSDI) questionnaire with objective tests in dry eye disease. Study Design: A prospective observational study. Place and Duration of the Study: Department of Ophthalmology, Nigde Omer Halisdemir University, Nigde, Turkiye, from 9th June to 31st December 2022. Methodology: All clinically diagnosed 323 eyes of patients with dry eye disease (DED) were included. The subjects were evaluated by the Oxford classification of corneal and conjunctival fluorescein staining, Schirmer I test, and fluorescein tear breakup time (TBUT). Symptoms of the patients were interpreted with OSDI and correlations of symptoms and objective markers were analysed. Results: There was no significant association between any objective signs (Schirmer I, TBUT, and Oxford), and OSDI (p = 0.26, 0.52, 0.18, and respectively). Schirmer I score showed a significant positive correlation with TBUT (p <0.001, r = 0.21) and a significant negative correlation with Oxford scale (p <0.001, r = -0.19). There was a statistically negative correlation between TBUT and Oxford scale (p <0.001, r = -0.37). Conclusion: Except for the Schirmer test, TBUT and Oxford scale are effective tools in the diagnosis of DED. Symptom markers, such as OSDI may have lower reliability in diagnosing DED and determining its severity. Diagnostic tests are important in the detection of asymptomatic or less severe dry eye disease that can be ignored. © 2024 College of Physicians and Surgeons Pakistan. All rights reserved