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    S(会告など)departmental bulletin pape

    Titanium dioxide nanoparticles exacerbate pneumonia in respiratory syncytial virus(RSV)-infected mice

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    九州保健福祉大学博士(医療薬学)平成27年度To reveal the effects of TiO2 nanoparticles, used in cosmetics and building materials, on the immune response, a respiratory syncytial virus (RSV) infection mouse model was used. BALB/c mice were exposed once intranasally to TiO2 at 0.5 mg/kg and infected intranasally with RSV five days later. The levels of IFN-γ and chemokine CCL5, representative markers of pneumonia, in the bronchoalveolar lavage fluids of RSV-infected mice had increased significantly in TiO2-exposed mice compared with the control on day 5 post-infection, but not in uninfected mice. While pulmonary viral titers were not affected by TiO2 exposure, an increase in the infiltration of lymphocytes into the alveolar septa in lung tissues was observed. Immunohistochemical analysis revealed aggregation of TiO2 nanoparticles near inflammatory cells in the severely affected region. Thus, a single exposure to TiO2 nanoparticles affected the immune system and exacerbated pneumonia in RSV-infected mice.doctoral thesi

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    Relationship between correct responses in consecutive rock–paper–scissors games and performance on the Trail Making Test

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    P(論文)This study examined the relationship between the number of correct responses in consecutive rock–paper–scissors games (tie, win, and loss) and performance on the Trail Making Test Part B (TMT-B). METHODS: Participants were 45 undergraduate students (16 males, 29 females) who played consecutive rock–paper–scissors games and completed the TMT-B. RESULTS: Differences among the numbers of correct responses were significant (tie: M = 43.20 > win: M = 34.78 > loss: M = 28.13). Although correlations between the number of correct responses and the time required to complete the TMT-B were significant (tie: r = − 0.407, p < .01; win: r = − 0.317, p < .05; loss: r = − 0.325, p < .05), correlations between the number of correct responses and the number of errors on the TMT-B were not significant. CONCLUSIONS: Results suggest that there are individnal differences in the number of correct responses in consecutive rock–paper–scissors games, and that consecutive rock–paper–scissors games and the TMT-B differ qualitatively each other.departmental bulletin pape

    Cognitive Benefits from Bilingualism and Second Language Study

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    P(論文)この数十年,一言語話者と比較した場合における二言語話者の認知的有益性を示唆する研究報告が増加し続けている。広範囲にわたる年齢層や学習状況を対象とした研究では,二言語話者および第二言語学習者は数々の認知タスクにおいて一言語話者よりも高い結果となり,複数の言語から得られた能力の有益性を示唆している。本稿では,これらの先行研究を概観し,第二言語習得における認知的有益性という新しい効果視点への認識を深める。During the past decades a growing number of research studies have found cognitive benefits for bi-lingual individuals in comparison to people who only speak one language. Across a broad range of ages and learning conditions research has found that bilinguals and students learning a second language perform better on a number of cognitive tasks and exhibit other benefits from their knowledge of more than a single language. This review presents a general summary of the findings to increase general awareness of the cognitive benefits of foreign language learning.departmental bulletin pape

    Psychological and Acoustics Effects of Heartbeat Sounds on Relaxation

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    P(論文)Aim: We conducted two studies to elucidate the relationship between heartbeat rhythms and relaxation among Japanese babies, young children, and their parents. Subjects and Methods: STUDY 1: Seven parents (age M = 34.3, SD = 5.5 years) with infants or toddlers (age M = 9.4, SD = 6.7 months) participated by listening to three conditions—a heartbeat sound, music, or music with a heartbeat sound—while completing a semantic differential exercise assessing musical imagery. Three types of music (classical, music box, and children’ s songs) were used. Image scores were compared among the three conditions in each type of music. STUDY 2: Participants included 161 parents who listened to three pieces of music, each with a different heartbeat rhythm (patterns A, B, and C). The parents reported their baby or child’ s responses to the music and also self-reported feelings they experienced. Finally, the parents indicated the piece of music they most preferred and related images using the SD exercise. To perform our analyses, we also assessed acoustic characteristics of the three heartbeat sounds. Results: STUDY 1: In the music arranged for a music box, participants evaluated musical imagery as significantly more “airy,” “comfortable,” “feels good,” “relaxing,” “easy,” “awake,” and “amusing” when listening to music with a heartbeat sound, in comparison to the other two conditions (p < .05). STUDY 2: “Rocking the body” and “heard quietly and slept” were the infants’ and toddlers’ responses to the music with a heartbeat sound. Fifty-six parents (34.8%) preferred “pattern A” music, 47 (29.2%) preferred “pattern B,” and 10 (6.3%) preferred “pattern C.” In analysis of “pattern A” acoustics, the mean number of heartbeats per minute, mean heartbeat frequency, maximum heartbeat frequency, and heartbeat Pitch Period Perturbation Quotient (PPQ) were 58/min, 120.3 ± 32.8 Hz, 248.4 Hz, and 11.39%, respectively. Conclusion: This research suggests that a heartbeat sound effective for relaxation has a rhythm of 60 beats/min, low-frequency bandwidth (120–220 Hz), and low percentage of PPQ. Our studies also indicate that music arranged for a music box with a heartbeat sound might be beneficial for inducing relaxation.departmental bulletin pape

    Editing Postscript

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    第5号 奥付

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    Relationship of evidence and narrative : A study reflecting the practical knowledge of elderly care professionals in safety management

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    P(論文)近年,医療専門職の経験・勘などの実践知を,科学的に検討する研究が増加しつつある。しかし,高齢者ケア専門職の実践知を検討した研究は少ない。そこで,高齢者ケア専門職の実践知を言語化(ナラティブの概念化)して,他の高齢者ケア専門職とこれらの概念を共有・蓄積(エビデンスの概念化)することは,高齢者ケアの現場での方法論として有益なツールになると推察した。本研究では,高齢者ケア専門職の実践知を, 日々の安全管理に反映させるために必要な知見を提言することを目的とした。本研究は文献研究である。本研究の目的を遂行するために,以下の手順で論を展開した。まず,先行研究を踏まえ,本研究における実践知を定義するための理路を提示した。次に,エビデンスとナラティブに関する先行研究からの知見を援用した。そして,これらの結果を統合して安全管理に反映させるための提言を行った。今後は,今回の提言を高齢者ケアの現場で検証していくことが必要である。Studies to scientifically examine practical knowledge such as experience and intuition of healthcare professionals have been increasing in recent years. Verbalizing practical knowledge of elderly care professionals (called concept of narrative) as well as sharing and compiling the practical knowledge with other elderly care professionals (called concept of evidence) may become valuable tools for elderly care settings. The present study, based on a literature review, examined the factors required for reflecting practical knowledge of elderly care professionals in daily safety management. In order to achieve the objectives of this study, l conducted a discussion in the following order: showing a method to define practical knowledge based on previous work, examining the relationship among practical knowledge, evidence, and narrative, and providing recommendations that reflect all the above results in safety management. In the future, it will be necessary to investigate these recommendations in elderly care settings.departmental bulletin pape

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