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児童発達支援施設を利用している子どもたちにおける走能力および跳能力の発達と運動支援
Full text link本研究の目的は児童発達支援施設を利用している子どもたちにおける走能力と跳能力の発達特徴を示し，運動能力を高めるための運動支援について検討することである．
分析対象者は体力測定会に参加した幼児48名とした．
分析対象者の中で児童発達支援施設を利用しているのは7名であった．
分析項目は25m走における中間区間の走動作と立ち幅跳びの跳び出し時の跳動作とした．
児童発達支援施設を利用している子どもたちの各測定項目の平均値を1標本Wilcoxon検定の検定値として児童発達支援施設を利用していない子どもたちの測定値と比した結果，走能力・跳能力に有意な差は認められなかった．
今回調査対象とした母集団において発達障害の有無と幼児期における移動系運動スキルの能力との間に関係性は認められなかった．
発達に遅れのある幼児への運動支援は運動好意感及び運動有能感を育み，運動を通して他児と関りを持つことが重要であると考えられた．departmental bulletin pape
薬学科5年生を対象とした患者シミュレータを用いたフィジカルアセスメント実技試験の評価
Full text linkThis study examines the practical implementation of a physical assessment using the patient simulator,
"Physiko," which to date, has been used for fifth-year students in the Department of Pharmacy’ s clinical
pharmacy course. With the introduction of the revised pharmacy curriculum in 2020, all fifth-year
students are now required to undergo this assessment, prompting the creation of new cases for the
practical examination.
Various cases were developed using "Physiko," incorporating differences in heart sounds, breath sounds,
pulse, blood pressure, bowel sounds, and edema. The examination duration was set at nine minutes, with
a total of 64 students participating. Approval was obtained from the Kyushu University of Health and
Welfare Ethics Review Committee for the publication of the study results.
The analysis of results revealed that the highest percentages of correct answers were observed for the
confirmation of edema (98.4%), arrhythmia (96.9%), and bowel sounds (93.8%). However, 46.9% of students
could not complete all items within the allocated time, with a notable focus on prolonged time spent on
blood pressure measurements.departmental bulletin pape
ヒト血清アルブミンおよびα1-酸性糖蛋白質の薬物結合サイトに結合するワルファリンとジアゼパムに対する長鎖脂肪酸と中鎖脂肪酸の影響
Full text linkThis study systematically evaluated the effects of long- and medium-chain fatty acids (LFAs and MFAs,
respectively) on human serum albumin (HSA) sites I and II and α1-acid glycoprotein (AGP) drug binding
sites using warfarin (site I) and diazepam (site II) as probes.
Free concentrations of warfarin and diazepam were quantified by UHPLC using ultrafiltration.
The results showed that the free fraction of warfarin was lower than that of the control, with increasing
[LFAs]/[HSA] (the free fraction of diazepam was markedly higher), whereas the free fraction of warfarin
was higher than that of the control, with increasing [LFAs]/[AGP] (the free fraction of diazepam was also
similar). In addition, the free fraction of warfarin was slightly higher than that of the control, with
increasing [MFAs]/[HSA] (the free fraction of diazepam was markedly higher), and the free fraction of
warfarin was slightly higher than that of the control, with increasing [MFAs]/[AGP] (the free fraction of
diazepam was also similar).
These data suggest that LFAs and MFAs either exert competitive or allosteric inhibition on the binding
of warfarin and diazepam to HSA and AGP. However, only LFAs may have a cooperative effect on
warfarin binding to HSA.departmental bulletin pape