Istanbul Arel University

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    3036 research outputs found

    Observation of a Near-Threshold Enhancement in the Lambda(Lambda)over-bar mass spectrum from e(+)e(-) -> phi Lambda(Lambda)over-bar at root S is from 3.51 to 4.60 GeV

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    The process e(+)e(-) -> phi Lambda(Lambda) over bar is studied using data samples collected with the BESIII detector at the BEPCII Collider at center of mass energies root S ranging from 3.51 GeV to 4.60 GeV. An enhancement is observed near the threshold of Lambda(Lambda) over bar. The lineshape of this enhancement is studied in different approaches, including fit with a Breit-Wiper function or a reversed exponential function. The Breit-Wigner function has a mass of (2262 +/- 4 +/- 28) McV/c(2) and a width of (72 +/- 5 +/- 43) MeV, where the quoted uncertainties are statistical and systematic, respectively. The rising rate of the reversed exponential function is measured as 33 +/- 11 +/- 6 MeV/c(2). For the Lambda(Lambda) over bar system, the J(PC) quantum numbers of 0(-+) and 0(+)(+) are rejected, while other J(PC) hypotheses are possible, according to the helicity-angle study. The energy-dependent cross section of the e(+)e(-) -> phi Lambda(Lambda) over bar process is measured for the first time in this energy region, and contributions from excited psi states and vector charmoniumlike Y-states are investigate

    Synthesis, Characterization and Biocompatibility Oo Plant-Oil Based Hydrogels

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    Biocompatible hydrogels are used in a variety of biomedical applications, including tissue scaffolds, drug delivery systems, lab/organ-on-a-chips, biosensors, cell-culture studies and contact lenses. The demand for novel and functional monomers to be used in hydrogel synthesis is increasing as the number of biomedical applications and need for biomaterials increase. The purpose of the study was to develop novel hydrogels from renewable materials. Acrylated methyl ricinoleate, a plant oil-based monomer, was used as the renewable material. The effects of acrylated methyl ricinoleate/N-isopropyl acrylamide molar ratio on hydrogel structural properties, thermal stability and in vitro cytotoxicity were studied. FTIR spectroscopy was used to characterize the structural properties of the hydrogels, while TGA was used to characterize the thermal properties. HEK293 and Cos-7 cell lines were used to test the cytotoxicity of the monomers and hydrogels. IC50 values for acrylated methyl ricinoleate and N-isopropyl acrylamide were found to be greater than 25 mg/mL. Cell viability of hydrogels containing 50% or more acrylated methyl ricinoleate was greater than 60%, while hydrogel biocompatibility decreased with decreasing molar ratio of acrylated methyl ricinoleate. Cells showed a minimum viability of 80% when incubated in hydrogel degradation products. An environmentally friendly synthesis method was developed and novel biocompatible hydrogels from renewable materials were produced for biomedical applications

    High Expression Level of miR-1260 Family in the Peripheral Blood of Patients with Ovarian Carcinoma

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    The most common gynecologic cancers detected in women in Turkey are uterine cancer, ovarian cancer, and cervical cancer. These data reported that a mean of 3800 individuals were diagnosed with uterine cancer, 2790 were diagnosed with ovarian cancer, and 1950 were diagnosed with cervical cancer, and 400 individuals were diagnosed with other gynecologic cancers each year in Turkey. A mean of 14.270 individuals were detected to have been diagnosed with gynecologic cancers each year in the United States of America (USA). Ovarian cancer treatment is generally composed of chemotherapy, and surgery. In general, chemotherapy is administered after surgery. The identification of the molecular pathogenesis of ovarian cancer, and discovery of new moleculer biomarkers which facilitate the ovarian cancer treatment are required for an effective ovarian cancer treatment in clinics. miRNAs are reported to be the possible biologic indicators for various cancer types. We aimed to investigate 2 miRNAs which were suggested to have effect in ovarian cancer in our (previous) monozygotic twin study from miR-1260 microRNA family whose association with ovarian cancer yet has not been reported in the literature. We investigated the expression levels of miR-1260a, and miR-1260b miRNAs, in the peripheral blood lymphocytes of 150 familial and sporadic ovarian cancer patients, and of 100 healthy individuals of the control group who were matched for age, sex, and ethnicity with the patient group, and investigated their possible property of being a biologic indicator for ovarian cancer. The expression results of ovarian cancer patients were evaluated by comparison of the results of the control group in the study. The expression levels of miR-1260a, and miR-1260b in ovarian cancer patients were found highly increased compared with the levels in the control group. miR-1260a expression level in ovarian cancer patients was detected to have increased approximately 17 fold compared with the control group, and miR-1260b expression level in ovarian cancer patients was detected to have increased approximately 33 fold compared with the levels in the control group. The String Analyses showed that the miR-1260a was associated with the ribosomal protein family which was known to be effective in the translation stage of cell and that miR-1260b was associated with CHEK2 protein which was a member of the serine/threonine-protein kinase family. It should be investigated for larger cohorts in benign ovarian diseases and in different stages of patients receiving ovarian cancer treatment whether these two molecules are a noninvasive biomarker and therapeutic target to be used especially in the early diagnosis and prognosis of ovarian cancer in future

    Measurement of the e(+)e(-) -> pi(+)pi(-) Cross Section Between 600 and 900 MeV Using Initial State Radiation (vol 753, pg 629, 2016)

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    In Ref.[1] the BESIII collaboration published a cross section measurement of the process e(+)e(-) -> pi(+)pi(-) in the energy range between 600 and 900 MeV. In this corrigendum, we report a corrected evaluation of the statistical errors in terms of a fully propagated covariance matrix. The correction also yields a reduced statistical uncertainty for the hadronic vacuum polarization contribution to the anomalous magnetic moment of the muon, which now reads as a(mu)(pi pi,LO) (600 - 900 MeV) = (368.2 +/- 1.5(stat) +/- 3.3(syst)) x 10(-10). The central values of the cross section measurement and of a(mu)(pi pi,LO) , as well as the systematic uncertainties remain unchanged. (C) 2015 The Author(s). Published by Elsevier B.V. All rights reserved

    Trigeminal Nerve Stimulation: A Recently Approved Treatment Approach in Attention Deficit Hyperactivity Disorder

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    Attention-deficit hyperactivity disorder (ADHD) with its high prevalence is a growing area of concern and research, whereas exact underlying pathophysiology remains unknown. Behavioral therapy and multiple medications include methylphenidate, atomoxetine, and amphetamines while trigeminal nerve stimulator (TNS) is the first medical device in ADHD with FDA approval. The aim of this article is to evaluate the latest studies in this field

    Experimental Investigation of the Microclimate Effects on Floating Solar Power Plant Energy Efficiency

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    Solar PVs are mostly built on uncultivated land. However, the increase in land values due to the increasing world population, the lack of suitable areas for potential PV plants, especially in the land-scarce countries, and the increasing energy need led researchers to seek new solutions. At this point, floating solar power plants emerge as a good alternative with their advantages such as not occupying land area and reducing water evaporation by covering the water surface. In this study, a floating photovoltaic power plant with 120 kWp installation power was installed on Buyukcekmece Lake, and the effect of the microclimate data on the produced energy of the system was investigated. Since the energy produced by PV panels is highly dependent on climate effects and there may be many climatic variations depending on the geographical conditions, experimental measurements have been made annually in this study and the results have been analyzed in order to contribute to the researches in this field. From the obtained results, it is seen that the most important factor that positively affects the energy produced is solar irradiance, while specific humidity, wave loads, and module temperature have a negative effect

    Measurement of the Born Cross Sections for e(+)e(-) -> eta'pi(+) pi(-) a t center-of-mass Energies Between 2.00 and 3.08 GeV

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    The Born cross sections for the process e(+)e(-) -> eta'pi(+)pi(-) at different center-of-mass energies between 2.00 and 3.08 GeVare reported with improved precision from an analysis of data samples collected with the BESIII detector operating at the BEPCII storage ring. An obvious structure is observed in the Born cross section line shape. Fit as a Breit-Wigner resonance, it has a statistical significance of 6.3 sigma and a mass and width of M = (2111 +/- 43 +/- 25) MeV/c(2) and Gamma = (135 +/- 34 +/- 30) MeV, where the uncertainties are statistical and systematic, respectively. These measured resonance parameters agree with the measurements of BABAR in e(+)e(-) -> eta'pi(+)pi(-) and BESIII in e+e(-) -> omega pi(0) within two standard deviations

    Low Dynamic Range Histogram Equalization (LDR-HE) Via Quantized Haar Wavelet Transform

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    Conventional contrast enhancement methods stretch histogram bins to provide a uniform distribution. However, they also stretch the existing natural noises which cause abnormal distributions and annoying artifacts. Histogram equalization should mostly be performed in low dynamic range (LDR) in which noises are generally distributed in high dynamic range (HDR). In this study, a novel image contrast enhancement method, called low dynamic range histogram equalization (LDR-HE), is proposed based on the Quantized Discrete Haar Wavelet Transform (HWT). In the frequency domain, LDR-HE performs a de-boosting operation on the high-pass channel by stretching the high frequencies of the probability mass function to the nearby zero. For this purpose, greater amplitudes than the absolute mean frequency in the high pass band are divided by a hyper alpha parameter. This damping parameter, which regulates the global contrast on the processed image, is the coefficient of variations of high frequencies, i.e., standard deviation divided by mean. This fundamental procedure of LDR-HE definitely provides a scalable and controlled dynamic range reduction in the histograms when the inverse operation is done in the reconstruction phase in order to regulate the excessive contrast enhancement rate. In the experimental studies, LDR HE is compared with the 14 most popular local, global, adaptive, and brightness preserving histogram equalization methods. Experimental studies qualitatively and quantitatively show promising and encouraging results in terms of different quality measurement metrics such as mean squared error (MSE), peak signal-to-noise ratio (PSNR), Contrast Improvement Index (CII), Universal Image Quality Index (UIQ), Quality-aware Relative Contrast Measure (QRCM), and Absolute Mean Brightness Error (AMBE). These results are not only assessed through qualitative visual observations but are also benchmarked with the state-of-the-art quantitative performance metrics

    Volumetric Analysis of the Brain Structures of Children with Down’s Syndrome: A 3D MRI Study

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    Down’s syndrome (DS) is one of the most common genetic causes of mental and cognitive retardation. In fact, it results in a number of characteristic neuropsychological and physical symptoms, including mental retardation. The aim of this study was to compare the brain structure volumes of children with DS to those of healthy children using MRI Studio in order to investigate whether there exists correlation between the developmental stages of DS and the results of both the Denver II Developmental Screening Test and magnetic resonance imaging (MRI) quantitative analysis. Five children diagnosed with Down’s syndrome (age range = 2–6 years) were matched for gender and age with five healthy comparison subjects. To analyse the overall and regional brain volumes, high-resolution MRI scans were performed and a morphometric analysis was conducted via MRI Studio software. The MRI T1 volumetric images were normalised using a linear transformation, which was followed by large deformation diffeomorphic metric mapping. Significant decreases (p0.05). It was further found that the developmental retardation observed in the children with DS, as detected using the Denver II test, increased due to decreases in the volumes of certain regions of the brain, although this was also not statistically significant (p>0.05). The results of this study generally confirm the findings of prior studies concerning the overall patterns of the brain volumes in children with DS and also provide new evidence of the abnormal volumes of specific regional tissue components among such a population. These results suggest that the brain volume reduction associated with DS may primarily be due to early developmental differences rather than neurodegenerative changes

    Observation of eta ' -> pi(+)pi(-)mu(+)mu(-)

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    Using (1310.6 +/- 7.0) x 10(6) J/psi events acquired with the BESIII detector at the BEPCII storage rings, the decay eta' -> pi(+)pi(-)mu(+)mu(-) is observed for the first time with a significance of 8 sigma via the process J/psi -> gamma eta'. We measure the branching fraction of eta' -> pi(+)pi(-)mu(+)mu(-) to be B(eta' -> pi(+)pi(-)mu(+)mu(-)) = (1.97 +/- 0.33(stat) +/- 0.19(syst)) x 10(-5), where the first and second uncertainties are statistical and systematic, respectively

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