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Preparedness and Response to COVID-19 Outbreak in Assam: An Experience from the Field
The world is now fighting against a new deadly virus disease, novel coronavirus disease (COVID-19), which is first declared as public health emergency and later declared as Pandemic by WHO. As COVID-19 spread around the world, governments, companies, international organizations announced measures to help contain the spread. Assam with 36 cases and the other north eastern (NE) states have been able to control the number of cases quite well compared to other states in India. To contain coronavirus spread in Assam, government leveraged nine projects implemented by Piramal Swasthya Management and Research Institute (PSMRI), in addition to other activities. This paper gives the elaborative listings of activities done by PSMRI in respond to COVID-19 outbreak to support the government respond to this pandemic. Activities are- Inbound calling, out bound calling, contact tracing, Visit and follow up of quarantined patients, data entry and updating Integrated Disease Surveillance Project (IDSP) portal and door step delivery of medicines. As on 26th April, 1,25,566 COVID-19 related calls received in 104-Health Helpline (HIHL). In addition, 37,886 beneficiaries called for quarantine follow up. Field staffs also visited households of home quarantined patients and screened more than 9000 people for COVID-19. PSMRI also supported in activities of Assam Cares Financial scheme and Dhanwantri Scheme.The above activities helped in mitigating the risk of coronavirus infection and also ‘helped in timely respond to the reported cases
The Conspicuous Lessons and Positive Impacts Observed Due to COVID-19 in Indian Economy
Like every occurring has positive and negative aspects, so is the COVID-19 outbreak. It is true that there are extreme consequences faced by the economies and the people across the world following this crisis, yet there are some lessons to be learnt from it to shield economy from any such disasters in future. Also, there are certain interesting positive outcomes of this crisis in different compasses of the Indian economy. This article aims to provide a holistic view of the ten lessons learnt as well as the positive outcomes of the pandemic in different spheres of the Indian economy. Some of such aspects are economic reforms, the plight of the farmers and migrant workers, measures taken and required for the marginalised sections, digitalisation and ecommerce operations, self-dependence within the economy, the effect on crime rates, consumerism and changes in spending patterns, lifestyle and working patterns, refraining from conspicuous spending, impact on health and healthcare, effect on science, indigenous innovation and research and the effects on environment. All these positive impacts of COVID-19 on the India will be highlighted in the article individually in separate sections
Cytokine Storm in COVID-19 Patients, their Impact on Organs and the Potential Treatment by QTY Code-Designed Detergent-Free Chemokine Receptors
The novel coronavirus in not only causing respiratory problems, it may also damage the heart, kidneys, liver and other organs; in Wuhan 14 to 30% of COVID-19 patients have lost their kidney function and now require either dialysis or kidney transplants. The novel coronavirus gains entry into humans by targeting ACE2 receptor that found on lung cells, which destroy human lungs through cytokine storms, this leads to hyper-inflammation, forcing the immune cells to destroy healthy cells. This is why some COVID-19 patients need intensive care. The inflammatory chemicals released during COVID-19 infection cause the liver to produce proteins that defend the body from infections. However, these proteins can cause blood clotting, which can clog blood vessels in the heart and other organs; as a result, the organs are deprived from oxygen and nutrients which could ultimately lead to multi-organ failure and subsequent progression to acute lung injury, acute respiratory distress syndrome and often death. However, a novel protein modification tool called the QTY code, that are similar in their structure to antibodies, which could provide a solution to excess cytokines, these synthetic proteins can be injected into the body to blind the excess cytokines generated by the cytokine storm; this will eventually remove the excessive cytokines and inhibit the severe symptoms caused by the COVID-19 infection. In this review we will focuses on cytokine storm in COVID-19 patients, their impact on the organs and the potential treatment by QTY code-designed detergent-free chemokine receptors
Current Economic Situation of India: Impact of COVID-19
The outbreak of the COVID-19 pandemic has greatly impacted the Indian Economy. The economy was already in a parlous state before COVID-19 struck. The prolonged lockdown in India will have a sizeable impact on the economy mainly on consumption which is the biggest component of GDP. The magnitude of the economic impact will depend upon the duration and severity of the health crisis, the duration of the lockdown and the manner in which the situation unfolds once the lockdown is lifted. In this paper we will discuss the impact of COVID-19 on various sector economy such as Tourism, Micro, Small and Medium Enterprises: Education and analyze the situation by using some indicators like the GDP growth rate, unemployment rate, Industrial Production, household income etc. This work mainly focuses on the situation in India pre-crises and during the crises to help understand the downturns and challenges faced by Indian Economy
COVID-19 Knowledge, attitude and prevention practice in southwest Nigeria
To assess COVID-19 knowledge, attitude and prevention practice as well as the associated factors among people living in Southwest, Nigeria. This was an online cross-sectional study among dwellers of southwest Nigeria. Data were collected online with kobo toolbox and analyzed using descriptive statistics, test of independence and binary logistic regression. Of the 286 study participants, 96.1% had good knowledge, 99.3% had positive attitude towards control of COVID-19, while 77.3% had good practices for prevention of the virus. Majority of the participants (86.9%) had tertiary education, 11.3% were 40years or older. Age and education were independently associated with COVID-19 prevention practice. After adjustment for some selected socio-demographic factors, only age of 10 – 19 years (OR: 3.83, CI: 1.05, 14), age 20-29 years (OR: 2.99, CI: 1.18 -7.55), and 30 -39 years (OR: 4.35, CI: 1.49-12.67) were more likely to have good practice of COVID-19 prevention compared to age >=40 years. The result revealed a high prevalence of good practices, and majority had good knowledge of COVID-19 and positive attitude towards control of COVID-19. Age and education were identified to be associated with practice of COVID-19 prevention. While further exploration revealed that elders (>=40years) were not likely to have good practice of COVID-19 prevention. We deduced that good practice of COVID-19 prevention was high in southwest Nigeria but notably low among elders and those who attained below tertiary education in southwest Nigeria. However, people of older age and poor education should be given much attention for proper enlightening and prevention strategies in this pandemic
Economic Valuation of Small Scale Water Management Intervention in Barind Area, Bangladesh
An Integrated Water Resources Management (IWRM) project is being implemented by DASCOH in the north-western part called Barind tract in Bangladesh. The primary goal of the project is to help local government institutions to contribute to the increasing availability of water for disadvantaged people in the Barind area through sustainable, effective, and inclusive management and usage of water resources. This study is designed under the scope of this project and cross-checks the achieved objectives in terms of how much benefit the project drips down to the targeted population. For all of the interventions implemented by the project, health and household labor cost reduction is found to be very significant. However, some interventions have a skewed impact on some particular parameters while others have a partial impact
THERMAL CONDUCTIVITIES OF SELECTED SOLID WASTE MATERIALS DETERMINED USING LEES’ DISC METHOD
In this study, the coefficients of thermal conductivities have been determined. The goal was to find out the best insulator among the recyclable and locally available materials which can be adopted for use to replace the existing thermal insulation. Rice husks, dry grass, sawdust and old/used newspapers have been studied in this study using Lees’ disc method. The results showed that grass can do best as an insulating material though all the samples can be used as insulators. They all have low thermal conductivities. The coefficient of thermal conductivities ranged from for grass, for saw dust, for rice husks and for newspaper cut-outs. Due to their local abundance, and no much competing commercial interest, we recommend the studied materials as suitable thermal insulators
Impact of gender differences and glycated haemoglobin on atherosclerosis risk in type 2 diabetic patients from north western Algeria: Impact of gender on atherosclerosis risk in diabetic patients
In type 2 diabetic patients, blood lipids and lipid ratios have been proven to be associated with atherosclerosis risk; however, results about the effect of gender differences had not been fully conclusive. In this transversal comparative study, a total of 129 adult type 2 diabetic patients (54 men and 75 women), from north western Algeria, was included to highlight the impact of gender differences on atherosclerosis risk (assessed by lipid ratios) according to their diabetic profile. Comparing between the two genders, no significant differences (p>0.05) were noted on diabetes duration, central obesity, body mass index and blood pressures. Moreover, the basic biochemical parameters of both glycaemic and lipid metabolism were not meaningfully divergent. However, higher significant values (p<0.05) of body weight, height, HbA1c levels, HDL and lipid ratios (TC/HDL, LDL/HDL and TG/HDL) were observed in male patients comparing to females. According to the HbA1c levels (HbA1c<7% vs.HbA1c ? 7%); notable higher CT/HDL, LDL/HDL and TG/HDL in male patients comparing to women were found. The rates of these three lipid ratios were often higher in both classes of HbA1c. The consideration of gender differences is very important for prevention, diagnosis, treatment and management of atherosclerosis and CVD. The disparity in atherogenic risk, in both genders, estimated by lipid ratios need to be critically examined. Further interventional studies are needed to determine how sex can modulate the impacts of diabetes control parameters on atherosclerosis risk
The Design of Chassis of SAE-Supra Motor Vehicle
Supra SAE INDIA is a national level event organized yearly by Society of Automotive Engineers India by Maruti Suzuki which gives a great platform for the young technocrats to test their engineering skills and refining them by learning from their works. The current study and experiment aims to design, develop and fabricate a low cost car without compromising the safety of the driver in accordance with the rulebook of SAE SUPRA given by SAE. A tubular space frame chassis is designed with a new idea for construction by the help of solid works, manufactured by the help of AISI 4130 based on the best performance and effectiveness. The design and development comprises of material selection, chassis design, cross section determination, determining strength requirements against failure and then fabricated in the workshop as per the tools availability and techniques with the students. All the process parameter is done according to the steps mentioned in the rulebook and the basic knowledge of chassis design
Role of Zidovudine and Candesartan in the Novel SARS-CoV-2 Treatment Trials: Theoretical Study
The coronavirus disease 19 (COVID-19) is a highly communicable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which aroused in Wuhan, China and stretch around the humankind. Genomic analysis exposed that SARS-CoV-2 is phylogenetically associated to severe acute respiratory syndrome-like (SARS-like) bat viruses, hence bats could be the possible primary reservoir. The intermediate obtains of beginning and relocation to humans is not known, however, the rapid human to human transfer has been confirmed commonly. There is no approved antiviral medicine or vaccine ready to be used against COVID-19. However, there are a few broad-spectrum antiviral drugs have been estimated against COVID-19 in the current clinical trials, resulted in clinical recovery. In the current review, we summarize the possibility to use Zidovudine as antiviral drug and Candesartan as Angiotensin II Receptor Blocker (ARB) on the basis that Zidovudine works as RNA reverse transcriptase inhibitor (RTI), in addition to Candesartan which act as ARB, the receptors that bind to the spike protein (S-protein) present in the surface of coronavirus