Ayushdhara (E-Journal)
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A Clinical Study to Evaluate the Comparative Efficacy of Phaltrikadi Kashaya and Phaltrikadi Kashaya Ghana Vati in the Management of Non-Alcoholic Fatty Liver Disease
Full text linkThe non-alcoholic fatty liver disease (NAFLD) has emerged as a leading type of chronic liver disease and a hepatic manifestation of “metabolic syndrome” worldwide. The emerging epidemic of childhood obesity means that increasing numbers of young people have NAFLD and early diagnoses followed by management are important. The only treatment options in early stages are weight loss, dietary fat reservation and exercise with strict control of associated diseases. A formulation mentioned in Ayurveda is Phaltrikadi Kashaya which is a combination of 8 widely used hepatoprotective herbs. But, since its preparation as a Kwatha in itself is a cumbersome task, so the present study has been planned to assess the comparative efficacy of Phaltrikadi Kashaya and Phaltrikadi Kashaya Ghana Vati in the management of NAFLD. 50 patients, within the age of 18-70 years, having aspartate amino-transferase (AST/SGOT) and alanine transaminase (ALT/SGPT) levels twice the upper normal limit and ultrasonographical evidence of fatty infiltration of liver, were selected and divided into 2 groups consisting of 25 patients each. Group I was managed with Phaltrikadi Kashaya in the dose of 50ml twice a day whereas, Group II was managed with Phaltrikadi Kashaya Ghana Vati in the dose of 500mg tablet, twice a day for a period of 12 weeks. Both subjective and objective parameters were assessed before and after the completion of trial. Data obtained during the trial was then tabulated and statistically analysed
A Comparative Clinical Study to Evaluate the Efficacy of Dhatri Lauha and Murvadi Yoga in the Management of Pandu Roga w.s.r to Iron Deficiency Anemia
Full text linkPandu is Varnopalakshita vyadhi. Vata and Kapha with Pitta as the predominant one aggravate in the Dhatus, as a result Dhatus become weak and heavy. By the vitiation of Doshas and Dhatus leads to the reduction in the properties of Ojas and leading to the symptoms like loss of complexion, strength etc leading to Pandu roga. Pandu roga is characterised by pale colour, depletion of blood and fat, weakness, weakened sense organs etc which can be correlated to Iron deficiency anemia. Iron deficiency anemia is the most common type of anemia worldwide. This occurs when iron or physiological requirements exceed absorption. This is the commonest nutritional deficiency and a major health problem globally. More than half of patients with anaemia are assumed to have iron deficiency. Between 30% and 70% population in the developing world is iron deficient. Ayurveda has a good approach in treating the Pandu roga. Acharyas have mentioned both Shodhana and Shamana line of treatment for Pandu roga. Hence the present study intends to clinical evaluation of the therapeutic effect of the formulation in patients of Pandu roga
Ayurvedic Management of Pittaja Kustha (Erythrodermic Psoriasis) Based on the Colour of Lesions
Full text linkKustha, an umbrella term in Ayurveda for various skin disorders, is characterized by lesions of differing colours. Classification of Kustha and its management based on Dosha predominance and type of lesions is mentioned in various Ayurveda texts. However, we also find a simple way of formulating management of Kustha based on colour of lesions. This case study investigates the Ayurvedic management of Pittaja Kustha, focusing on the colour of lesions as a basis for treatment. Objectives: To assess the effectiveness of Ayurvedic treatments tailored to the colour of Kustha lesions with respect to Pittaja kustha and their impact on patient outcome. Methods: A case study was conducted on a patient with red coloured Kustha lesions. Treatments were customized based on colour; Virechana (purgation therapy) and Jaloka (leech therapy) were administered to the patient. Results: The patient showed significant improvement in red types of lesions. Red lesions improved with Virechana and Jaloka (leech therapy). Overall, the patient\u27s skin condition and general health enhanced markedly. Conclusions: This study highlights the efficacy of colour-based Ayurvedic management of Pittajakustha, demonstrating that individualized treatment protocols can significantly improve patient outcomes
Exploring the Efficacy of Matra Basti in Managing Janusndhigata Vata
Full text linkSandhigata vata is the most common articular disorder. It is a type of Vatavyadhi which mainly occurs in old age due to Dhatukshaya. Sandhigata vata mainly presents with Sandhi shoola and Shopha further leading to difficulty in movements. If these Lakshanas are observed in the Janu Sthana, the condition is referred to as Janusandhigata Vata, which can be correlated with osteoarthritis. The prevalence of osteoarthritis among the elderly, as per a recent study, is 56.6%. The present case study involves a 60-year-old female patient presenting with a two-year history of pain and swelling in both knee joints, along with an inability to walk independently without walker over the past 15 days. The condition was diagnosed as Janusandhigata Vata (osteoarthritis of the knee joints). For its management, Godhumadi upanaha, Sarvananga abhyanga with Ksheerabala taila followed by Shashtikashali pinda sweda followed by 21 days Matra basti with Ksheerabala taila and Guggulu tiktaka grita and Shamana chikithsa were administered. Following the procedure, the patient experienced significant relief in both subjective and objective parameters like X-ray
An Insight to Geriatric Depression Jarajanya Vishad and its Management
Full text linkAccording to an Indian systematic analysis, 34.4% of elderly individuals suffer from GD. Ayurveda considers aging (Jara) as a natural process associated with mental changes, including Vishada (depression), which is correlated with geriatric depression. Methods: A comparative analysis of contemporary medical perspectives and Ayurvedic principles was conducted to understand the etiology, pathophysiology, and treatment of geriatric depression. Literature from modern psychiatry and classical Ayurvedic texts was reviewed, emphasizing Vishada as a Vataja Nanatmaja Vyadhi and its correlation with GD. Evaluation methods included standardized depression scales like the Geriatric Depression Scale, PHQ-9, and Hamilton Depression Scale. Results: The study highlights key etiological factors of GD, including neurotransmitter imbalances, chronic illnesses, and psychosocial stressors in modern medicine, while Ayurveda attributes Vishada to vitiation of Vata and Tamas guna. Pathophysiology suggests depletion of Dhriti (mental strength), Smriti (memory), and Buddhi (intellect), leading to Vishada. Contemporary treatment primarily involves SSRIs, psychotherapy, and lifestyle interventions. Ayurveda recommends a whole system approach integrating Shodhana (purification), Shamana (pacification), Satvavajaya (mind therapy), Daivavyapashraya (spiritual healing), and lifestyle modifications. Conclusion: A multidisciplinary approach combining Ayurveda and modern medicine may offer a comprehensive strategy for GD management. Early diagnosis and integrative treatment can significantly improve the quality of life in elderly individuals
Ayurvedic Insight into Tonsillitis (Tundikeri)
Full text linkTuṇḍikerī is an Ayurvedic condition classified under Mukha Roga and is described as a swelling at the base of the Hānusandhi (temporomandibular joint), resembling the Vanakarpaṣā phala cotton fruit). Based on its signs and symptoms, Tuṇḍikerī corresponds closely to tonsillitis i.e., the inflammation of the tonsils, which are paired, oval lymphoid tissues at the throat’s back. Typical features include swollen tonsils, Galāśūla (sore throat), Jvara (fever), Karṇaśūla (ear pain), Galoparodha (difficulty swallowing), and enlarged, tender lymph nodes in the neck region. Material and Methods: A 25-year-old male patient presenting with clinical features resembling Tundikeri (tonsillitis) was treated using Ayurvedic oral medications along with Pratisarana and Kawal. The patient\u27s condition was assessed using Brodsky grading and other symptom-specific subjective parameters following a 45-day therapeutic regimen. Follow-up evaluations were conducted both during and after the treatment period to monitor progress and outcomes. Result: The subject showed marked improvement as depicted in the photographs taken before and after treatment. Discussion: While allopathic medicine may offer symptomatic relief for tonsillitis, it often falls short in ensuring complete recovery and preventing recurrence. In contrast, Ayurveda, as outlined in classical Samhitas, provides a comprehensive approach that includes both internal medications and external therapies such as Pratisarana and Kawal. This article highlights the effectiveness of these Ayurvedic treatment modalities in managing Tundikeri, demonstrating their potential for more sustainable and holistic outcomes. Conclusion: By adopting the holistic approach with external treatment modality an attempt is made to bring about satisfactory results
Ayurvedic Approach in the Management of Dyslipidaemia
Full text linkDyslipidaemia, commonly characterized by deranged serum lipids, corresponds to Medoroga (dyslipidaemia) in Ayurveda, a condition arising from Meda Dhatu Dushti (vitiated fat tissue) due to Kapha-Medo Vriddhi (increase of Kapha and Meda dhatu). This case study presents a 46-year-old male patient who complained of fatigue, breathlessness on exertion, excessive sweating, and disturbed sleep. Patient lifestyle included a sedentary routine, irregular food habits, and high intake of oily and processed foods. Initial lipid profile showed raised Triglycerides (288mg/dL) and VLDL (very low-density lipoprotein) (58mg/dL), indicating Rasa-Meda Dushti and impaired Agni. An Ayurvedic line of treatment focusing on Agnideepana (stimulation of digestive fire), Amapachana (digestion of toxins), Medohara (fat reducing) and Kapha-Vata shaman was initiated, comprising of classical formulations, dietary correction (Pathya-Apathya), and lifestyle modifications including regular exercise and stress management. After a treatment duration of 1-month, significant clinical improvement was observed Triglycerides dropped to 123mg/dL and VLDL (very low-density lipoprotein) to 25 mg/dL. The patient reported improved energy levels, better sleep quality, and reduced sweating. This case underlines the effectiveness of integrative, individualized Ayurvedic management in addressing dyslipidaemia holistically by correcting the root cause rather than just controlling serum lipid values
A Review on Stevia rebaudiana - A ray of hope for diabetic patients
Full text linkDiterpene glycosides found in Stevia rebaudiana leaves provide food items a sweet flavour but no calories. For generations, the indigenous Guarani Indians of South America have used stevia as a sweetener to offset the harsh flavour of a variety of medications and drinks. This plant produces diterpene glycosides, which are used as sweeteners in foods and drinks since they are 100–300 times sweeter than sucrose. They have no shelf-life restrictions and stay stable in food items over a broad range of pH and temperature conditions during processing. These glycosides are appropriate for diabetics and obese people since they do not cause a glycaemic reaction when consumed. India has a large potential market for this natural sweetener due to the country\u27s rising rates of obesity and diabetes
Hypothesizing the Mechanism of Action of Virechana in Neurological Diseases with Respect to the Gut-Brain Microbiota Axis
Full text linkPanchakarma is an efficient and popular Ayurvedic treatment modality that helps eliminate various Doshic imbalances in the body to prevent and treat diseases. Its efficacy is being proven through multiple studies conducted across the globe; still, the mode of action of these therapies is to be understood far and wide. Virechana is one of the Panchakarmas that have an impact on the whole body to remove the Doshas that spread across the entire system. Due to this reason, it is considered best in the management of many disorders affecting different systems of the body, including the nervous system. The present review aimed at understanding the mechanism of action of Virechana with respect to the microbiota-gut-brain axis in neurological diseases. Virechana using Mridu and Snigdha medicines is mentioned for the management of Vatarogas. As Virechana is considered the primary treatment of pitta, its effect may be related to hormones and enzymes having neuroregulatory properties also. The microbiota-gut-brain axis plays an active role in the pathogenesis, management, and prevention of neurological diseases. Gastrointestinal complications like constipation are common in diseases affecting the nervous system, and they have shown a negative correlation with neurological recovery. Here comes the importance of Snigdha virechana or Mridu virechana mentioned in Vatavyadhi. Virechana can remove unfavorable bacterial colonization and is effective in correcting gut flora dysbiosis. Thus, the mechanism of action of Virechana in modifying the gut-brain axis and thereby facilitating neurologic recovery is understood. The present review sheds light on the Mechanism of action of Virechana with respect to the microbiota gut-brain axis in neurological disorders, which may be helpful for further research
Comparative Quantitative Assay of Apigenin and Luteoline Study of Different Market Samples of Bharangi (Clerodendrum Serratum Linn) w.r.t. UPLC
Full text linkBharangi (Clerodendrum Serratum Linn) is one of ancient drug used in many preparations for treatment of many pathological conditions like Kasa, Shwasa, Jwara, Gulma, Aruchi, etc. That’s why there is need of pharmacognostical and phytochemical screening of different market samples of Bharangi (Clerodendrum Serratum Linn) with the help of UPLC study. Objectives: To undertake pharmacognostic and phytochemical screening of different market samples of roots of Bharangi (Clerodendrum Serratum Linn) and to compare the apigenin and Luteolin quantitatively in different market sample of root of Bharangi with the help of UPLC study. Materials and Methods: This was a laboratory-based study that included the analysis of different market samples of Bharangi (Clerodendrum Serratum Linn) in 3 phases, such as follows; a) Macroscopic and microscopic examinations with physio-chemical assessment involving the examination of ash value, pH water soluble extract, methanol - soluble external, acid insoluble ash and the extraction of volatile oil utilizing a clevenger apparatus. b) A qualitative phyto-chemical screening is conducted-demploying TLC method followed by phase 3 c) Which involves UPLC study. Results: The present showed that the market sample from Bengaluru had the highest quality of luteolin followed by Delhi and Rajasthan. All the three samples of Bharangi (Clerodendrum Serratum Linn) comprised both apigenin and luteolin with variations in both the quantity and this could be because of various factors such as soil properties, cultivation methods, environment, collection methods, extraction methods and age of plant. Conclusion: All the samples of Bharangi (Clerodendrum Serratum Linn) successfully fulfilled all the pharmacopoeia standards hence they are suitable for medicinal use