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    Clinical Evaluation of Panchakola Siddha Yavagu and Simhanada Guggulu in the Management of Amavata

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    Amavata, a chronic inflammatory condition, arises from vitiation of Vata associated with Ama (metabolic toxins). The vitiated Vata circulates Ama through channels (Dhamanis) and localizes in Shleshma Sthana (joints, stomach, etc.), producing stiffness, swelling, and pain. In Ayurveda, management emphasizes Deepana, Pachana, Virechana, Snehapana and Basti. Pathya plays a crucial role in the management of Amavata. In contemporary science it is correlated with Rhematoid Arthritis (RA). As the disease progresses the symptoms verses and it may lead deformity. Objective: To evaluate the therapeutic effect of Panchakola Siddha Yavagu and Simhanada Guggulu in an Amavata patient. Methodology: A 34-year-old female presented with multiple joint pain (dominantly knees), morning stiffness, swelling, anorexia, and difficulty in ambulation. Laboratory reports revealed raised inflammatory markers. She was administered Panchakola Siddha Yavagu (250ml daily on empty stomach) and Simhanada Guggulu (500mg twice daily) for 14 days with dietary guidelines. Follow-up was done on the 15th and 30th day. Results: Remarkable improvements were observed, including reduced joint pain, stiffness, and swelling. ESR decreased from 80 to 40, CRP from 9 to 8, and RA factor from 23 to 20. Appetite and mobility improved notably, and by the 30th day the patient was asymptomatic. Discussion: Panchakola supports Deepana and Pachana, aiding Ama Pachana. Simhanada Guggulu combines Shodhana and Shamana effects, exhibiting strong anti-inflammatory and analgesic actions. The combined therapy reduced inflammatory markers and enhanced quality of life. Conclusion: The cost-effective and simple regimen of Panchakola Siddha Yavagu with Simhanada Guggulu proves highly effective in managing Amavata

    Low Back Pain, Ergonomics and Ayurveda - A Clinical Insight

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    Low back pain (LBP) is a major cause of global disability, with most cases being non-specific and influenced by physical, psychosocial, and lifestyle factors. Conventional approaches involving physiotherapy and NSAIDs often yield limited outcomes, emphasising the need for individualised, holistic care. This review integrates modern ergonomic principles with Ayurvedic concepts to establish a comprehensive framework for LBP prevention and management. Methodology: Data were compiled from classical Ayurvedic texts and biomedical literature in databases such as PubMed and Google Scholar. The review synthesised evidence on the prevalence, aetiology, and management of LBP, with particular focus on ergonomics and Ayurvedic interventions. Keywords included “Low Back Pain and Ayurveda,” “Ergonomics and Ayurveda,” and “Musculoskeletal Disorders and Preventive Strategies.” Occupational health scenarios were also analysed to merge theoretical and clinical insights. Review Results: LBP, often corresponding to Ayurvedic Vata Vyadhi conditions like Gridhrasi, Katigraha, and Katishoola, arises mainly from biomechanical strain and poor ergonomics. Prolonged static postures and repetitive movements exacerbate Vata imbalance. Modern ergonomic strategies, such as adjustable workstations and posture retraining, directly mitigate these factors. Complementary Ayurvedic therapies, such as Basti (medicated enema), Snehana (oleation), Swedana (sudation), and herbal formulations like Trayodashanga Guggulu, restore Doshic equilibrium and strengthen tissues. An integrative model that unites ergonomic optimisation with Ayurvedic therapies shows promise for sustainable relief and recurrence prevention. Conclusion: Integrating ergonomic principles with Ayurvedic management offers a patient-centred strategy that addresses both biomechanical and physiological dimensions of LBP. Future multi-centric randomised trials are needed to validate and standardise this integrative approach

    Ayurvedic Management of Papular Dermatosis

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    Papular dermatoses are a group of skin disorders characterized by multiple small, raised papules, among which lichen nitidus is one of the uncommon variants. It is a rare, chronic inflammatory condition of the skin, mostly in children and young adults. It may cause considerable discomfort due to pruritus and may necessitate treatment for cosmetic or symptomatic relief. This case study explores the diagnosis and Ayurvedic management of a 17-year-old male patient with papular lesions on the scalp, for whom a probable diagnosis of lichen nitidus was considered based on clinical features. Management incorporated a Dosha-based approach along with Ayurvedic principles of Kushta Roga, using oral formulations and topical applications. The patient experienced symptomatic improvement, with reduced itching and complete resolution of lesions. This case highlights the potential role of Ayurvedic management in papular dermatoses and emphasizes the need for further exploration of Ayurvedic principles in their management through well-designed clinical studies

    Daiva as Dravya: Recontextualizing Daivavyapashraya Chikitsa through the Lens of Atharvaveda and Psychodermatology

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    Daivavyapashraya Chikitsa, one of the three main categories of treatment in Ayurveda, is often perceived as spiritual or religious therapy aimed at alleviating diseases caused by unseen forces (Adrishta). Although this form of therapy has often been ignored as non-rational or non-clinical, a deeper analysis reveals its organized and purposeful nature. Ayurveda is an Upaveda of the Atharvaveda. Atharvaveda, the fourth Veda, is a primary textual source that closely aligns with Ayurvedic philosophy and practices. It presents many Sukta (hymns) that directly address disease, mental imbalance, possession, poison, infertility, and skin afflictions, often prescribing ritual and verbal treatments that mirror Daivavyapashraya practices. Sukta like Kushthanashana Sukta, Kriminashana Sukta, etc., reveal the early integration of Mantra and other disciplines into therapeutic frameworks. By re-evaluating Daivavyapashraya through the Atharvavedic lens, this study highlights its foundation in textual tradition and its relevance as a valid and well-organized healing system. It bridges spiritual, psychological, and somatic domains, making it particularly applicable to the management of psychosomatic and psychodermatological conditions in the present era. This recontextualization encourages the inclusion of Daivavyapashraya in integrative medicine, emphasizing its preventive, promotive, and curative aspects. This review advocates the concept of “Daiva as Dravya,” viewing divine interventions as therapeutic elements rather than abstract metaphysical concepts

    A Case Report on the Efficacy of Ayurvedic Intervention in Non-Alcoholic Fatty Liver Disease (Grade 2)

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    Non-Alcoholic Fatty Liver Disease (NAFLD) has emerged as a leading cause of liver-related morbidity and mortality worldwide, characterized by excessive fat accumulation in hepatocytes in individuals who consume little to no alcohol. The disease encompasses a spectrum ranging from simple steatosis to non-alcoholic steatohepatitis (NASH), which can progress to advanced fibrosis, cirrhosis, and hepatocellular carcinoma. the pathogenesis of NAFLD is complex and multifactorial, involving genetic predisposition, environmental influences, and lifestyle factors such as diet and physical inactivity. Early stages of NAFLD are often asymptomatic, complicating timely diagnosis. Management strategies for NAFLD primarily emphasize lifestyle modifications, including weight loss, dietary changes, and regular physical activity. In this case study, effect of Ayurvedic intervention in grade 2 fatty liver reported forty-year-old obese female with grade 2 fatty liver presented with compliant, on Haematological examination revealed altered total cholesterol low density lipoprotein and triglyceride and also alanine transaminase fasting blood glucose. The patient was diagnosed sonological with grade 2 fatty liver the patient was given Ayurveda treatment for sixty days with 3 treatment regimen and two settings of Raktmokshana (Siravedha). the clinical improvement in the patients sign and symptom was monitored, in haematological parameters after sixty days significant improvement was observed in symptoms no fatty tissue was reported sonological and every changed biochemical parameter within normal bound. The potential of Ayurvedic treatments in the treatment of obesity and non-alcoholic fatty liver disease is demonstrated by the current case

    Yakrut Karma in Post-Covid Sequelae: An Integrative Review

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    Post-COVID syndrome presents with a wide range of persistent symptoms, including fever, fatigue, hypertension, anorexia, digestive ailments, body aches, nausea, and malnutrition. According to Ayurveda, all these manifestations closely resemble the classical symptoms of Rasa Dhatu Dushti. When the quality of Rasa is compromised, its successive transformation into Rakta Dhatu is hindered, predisposing to disturbances in the blood tissue and related metabolic domains, with the Yakrut presenting as the primary site of dysfunction. This review analyses post-COVID sequelae in the framework of Yakrut Karma and Rasa–Rakta Dhatu Dushti, investigating how persistent changes in Rasa Dushti after COVID can result in underlying Rakta Dushti, which ultimately presents as liver damage. Modern clinical findings such as higher liver enzyme levels, metabolic disturbances, and persistent inflammation correlate with the Ayurvedic overview of impaired Yakrut Karma, indicating altered liver function and metabolism. An effort has been undertaken to connect recent scientific evidence with traditional interpretations of Dhatu imbalance, highlighting the importance of Ayurveda in assessing liver health following COVID-19

    A Case Study on Ayurvedic Management of Bahya (Pada) Vidradhi

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    Bahya Vidradhi, particularly Pada Vidradhi, refers to an external abscess characterized by inflammatory swelling, pain, and pus formation. This case study presents a 67-year-old diabetic male with swelling and pain below the left knee, diagnosed as Bahya Pada Vidradhi. The patient was treated using a holistic Ayurvedic approach, including internal medications (Triphala Guggulu, Gandhaka Rasayana, Gokshuradi Guggulu, Punarnava Mandura, and Swarasas), along with aspiration and surgical intervention (incision and drainage). Over 30 days, significant clinical improvement was observed- pain reduced from VAS 8 to 2, swelling subsided, and pus was drained successfully. The site healed with a fibrous scar, and no adverse effects were reported. This outcome supports the effectiveness of Ayurvedic management in treating abscesses, particularly when conventional therapies pose risks or limitations. The case highlights the relevance of classical Ayurvedic principles in modern clinical practice

    Concept of Kriyakala Mentioned in Sushruta Samhita

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    In Ayurveda, a diagnosis is made based on the nature of the phenomenon rather than the name of the illness. This phenomenon is explained in terms of each patient\u27s Samprapti, which consists of components related to Dosha, Dushya, and Adhishtana. Dosha and Dushya play a major role in the pathophysiology of the illness. The term "Shat Kriyakala" describes the stage of a pathological process in which a doctor can intervene by using the most appropriate medication and treatment method, stopping the illness process\u27s advancement. The 21st chapter of Sushruta Samhita Sutrasthana has a detailed explanation of Shatkriyakala by Acharya. Sanchaya, Prakopa, Prasara, Sthansamshraya, Vyaktavastha, and Bhedavastha are the six phases of Shatkriyakala. In the twelfth chapter of the Astang Sangrah Sutrasthana, Vagbhat explains the Ritu Kriya Kala. There are just three: Chaya (1), Kopa (2), and Prashama (3). The influence of being is what causes these three stages of Doshas. People will return to their normal state if they follow the current ritual routine. At that point, using his intelligence and understanding to recognize the vitiated Dosha situation, Kriya Kala assists the doctor in choosing a course of therapy

    The interplay of Epigenetics, Gut Dysbiosis, Ama and Mandagni in Autoinflammatory pathogenesis of Ankylosing Spondylitis - a Scientific Review

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    Ankylosing Spondylitis (AS) is a chronic autoimmune disorder primarily affecting the spine and sacroiliac joints, often leading to progressive stiffness, pain, and structural damage. Despite advances in conventional treatment, existing therapies remain largely palliative, with no definitive cure. This review explores the pathogenesis of AS through the interplay of epigenetics, gut dysbiosis, and metabolic dysfunction, emphasizing their correlation with Ayurvedic concepts such as Ama and Mandagni. Emerging evidence suggests that gut microbiome imbalances contribute significantly to chronic inflammation in AS, promoting immune dysregulation through antigenic mimicry and intestinal barrier dysfunction. Ayurveda describes a similar mechanism wherein improper digestion leads to Ama formation, which, under the influence of Mandagni, penetrates systemic circulation and triggers inflammatory cascades. The review integrates modern and Ayurvedic perspectives, proposing that Mandagni, or metabolic hypofunction, is the underlying factor connecting gut dysbiosis, chronic inflammation, and immune dysfunction. Furthermore, epigenetic modifications influenced by diet, lifestyle, and environmental factors act as triggers in genetically predisposed individuals, aligning with the Ayurvedic notion of Nidana (causative factors). A comparative analysis of modern and Ayurvedic treatment modalities highlights the potential role of Sopha and Vatavyadhi management in addressing the root causes of AS. Therapeutic interventions such as dietary modifications, gut microbiome restoration, detoxification (Shodhana), and Rasayana therapy may provide a holistic approach to disease prevention and management

    A Clinical Study on the Effect of Virechana Karma with Gandharvahastadi Kwath in the Management of Amavata w.s.r to Rheumatoid Arthritis

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    Purpose: Amavata, which resembles rheumatoid arthritis, affects communities. Ayurveda is being considered as a treatment for Amavata because conventional medicine often fails. This study examines Gandharvhastadi Kwatha\u27s management of Amavata. Amavata is a difficult situation (Krichra Sadhya Vyadhi) induced by Vata vitiation, Agni Vaishamya, and toxin accumulation. Madhavakara called it "Sa kashtah sarva roganam," signifying its ferocity. Amavata is mostly an Ama-related illness, hence its treatment involves detoxification. Virechana (purgation therapy) and Gandharvhastadi Kwatha are tested for treating Amavata (RA). Methods: Open-label, randomized preliminary clinical study. Patients with classical Amavata symptoms and meeting inclusion and exclusion criteria were selected from G.A.C.H, Patna\u27s OPD and IPD. The study involved 40 patients in two phases: Amavata assessment criteria creation and validation and clinical evaluation. The assessment instrument had patient-reported symptom scores. To verify reliability and validity, randomly chosen RA/Amavata patients\u27 data was statistically analyzed. Results: Virechana and Gandharvhastadi Kwatha improved various clinical indicators. Statistically substantial improvement was seen in morning stiffness (83.02%), swelling (81.67%), excessive thirst (56%), loss of appetite (80.00%), body heaviness (85.37%), and indigestion (81.39%). Patients experienced significant anti-inflammatory and pain-relieving benefits and functional gains. Conclusion- RA is an autoimmune condition, thus standard treatments include immunosuppressants like NSAIDs and corticosteroids, which relieve symptoms but have serious adverse effects. Modern RA treatment is inconsistent and unsafe. However, Gandharvhastadi Kwatha, along with Virechana cleansing and Samshamana Chikitsa (palliative treatment), is safer and more successful. This complete Ayurvedic treatment for Amavata reduces risks and improves outcomes

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