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A Comprehensive Review of Achyranthes Aspera: Ethnopharmacology, Phytochemistry, and Therapeutic Potential
Get PDFAchyranthes aspera, commonly known as "Prickly Chaff Flower," is a medicinal plant with significant ethnopharmacological importance, deeply rooted in various traditional healing systems worldwide. This comprehensive review paper aims to consolidate and analyze the existing scientific literature on Achyranthes aspera, focusing on its ethnopharmacological significance, phytochemical composition, and diverse pharmacological activities. The plant\u27s historical use in traditional medicine systems for the management of inflammation, wounds, gastrointestinal disorders, respiratory ailments, and pain underscores its cultural significance and therapeutic potential. Over the years, researchers have explored its bioactive compounds, which include alkaloids, flavonoids, saponins, and triterpenoids, attributing these constituents to its various pharmacological effects. The pharmacological activities of Achyranthes aspera encompass anti-inflammatory, antioxidant, antimicrobial, analgesic, and immunomodulatory properties, among others. These diverse activities have piqued the interest of pharmaceutical researchers and healthcare practitioners, making the plant a promising candidate for drug development and formulation of standardized herbal preparations. Despite its rich traditional use and growing scientific interest, the safety and toxicity of Achyranthes aspera require further investigation. Adequate toxicological studies are essential to determine safe dosage levels and potential adverse effects
A Comparative Clinical Study to Determine the Efficacy of Bhudhatrayadi Yoga and Metformin in the Management of Madhumeha w.s.r. to Type II Diabetes Mellitus
Get PDFPrameha is a chronic disease that is described in all the classics of Ayurveda. Madhumeha is categorised as a subtype of Vataja Prameha. Vata Dosha is mainly vitiated in Madhumeha. The patient passes large quantity of urine which is Kashaya (astringent), Madhura (sweet), Pandu (pale) and Ruksha (dry). Madhumeha is the final stage of all the Prameha when left untreated for long time becomes difficult to treat. In modern medicine signs and symptoms of Madhumeha resembles Type II Diabetes Mellitus. Diabetes is a metabolic disease and is characterised by increase in blood glucose levels, deficiency of insulin or resistance to insulin uptake. 40 patients were selected from the IPD and OPD of Kayachikitsa Department of R.G.G.P.G. Ayurvedic College and Hospital, Paprola, Himachal Pradesh. 20 patients were managed with Bhudhatrayadi Yoga and 20 patients were managed with Tablet Metformin. Bhudhatrayadi Yoga showed moderate improvement in subjective parameters of Madhumeha in the study
To Evaluate the Efficacy of Gunjaphaladi Lepam and Vibhitakadi Kwatha in Management of Switra w.s.r to Vitiligo
Get PDFSwitra is type of Kushta roga often encountered by Ayurvedic pediatric OPDs characterized by Twak swetata (white discolouration of skin). it is caused due to involvement of Tridoshas and Dhatus like Rasa, Rakta, Mamsa, Meda. Based on the symptoms Switra can be correlated with vitiligo in modern science. Vitiligo is a common pigmentary disorder of great socio-medical importance. Vitilogo is an acquired macular depigmentation disorder associated with the destruction of melanocytes. It affects approximately 0.5-2% of world population.
In children Shamana is preferred than Shodhana therapy. So, a clinical study aimed to evaluate the efficacy of Gunjaphaladi lepam and Vibhitakadi kwatha in Switra in children 6-16 years of age was conducted considering inclusive and exclusive criteria. Patients were given Gunjaphaladi lepam for external application and Vibhitakadi kwatha internally for 60 days and called for follow up after 30 days of completion of treatment. Among 30 patients, maximum patients were having mild improvement i.e., 56.66%, 17% showed complete remission and 13.33% showed moderate improvement. The clinical study clearly concludes that Gunjaphaladi lepam and Vibhitakadi Kwatham are safe and effective in the management of Switra in children
A Critical Appraisal of Manikya: A Ratna
Get PDFRasashastra has used almost all the available metals and minerals in the creation for medicinal purpose. Gems or Ratnas are also one among them. As the priority of Rasashastra was to attain a body (Deha vada), Siddhahcaryas of Rasashastra had used the gems for the purpose of inducing the longevity of life in a human body. Manikya or ruby, the rarest of gemstones and grouped under Ratna Varga. Its use leads to generate the mental and spiritual powers and special divine thoughts rise in mind. Manikya or ruby balances Surya (sun). Surya represents the king of the solar system in Jyotish. It also represents authority, power, self, father, body and health. It is composed of aluminium oxide, chromium and titanium. Manikya is having innovate action on various hormonal, enzymatic, immunological pathways, as it comprises mainstream trace elemental moieties. It is a versatile drug having Medhya, Vrushya property and specially recommended in Dwajabhanga, Kshaya and it has best Rasayana and Vajeekarana property. In the present review an attempt has been made to compile historic review, mythological origin of Manikya, Synonyms according to different Acharyas, Manikya Guna Karma and Dharana punya, types and their Lakshana, Grahyagrahyatva etc. present review expected to furnish the knowledge on Manikya ratna so that it can be widely used in therapeutic practices
A Narrative Review on Therapeutic Potential and Efficacy of Medhya Rasayana
Get PDFAnything that imbalance body and mind is known to cause disease. Nowadays, mental health has been becoming a global threat to the world. Ayurveda has a novel concept of Rasayana. Medhya Rasayana that has been classified under Rasayana for the stability of Dhi, Dhriti, Smriti. The action of Medhya Rasayana is explained with the help of using neurons and neurotransmitters in modern neurophysiology. Information is gathered from various Nighantus, Samhitas, other Ayurvedic textbooks and various online sources such as Google scholar, Sci-hub, Science Direct etc. Medhya Rasayana has a very good anti-oxidant, adaptogenic, anabolic, anti-stress and anti-depressant property. This literature review article is about the four medicinal plants such as Mandukaparni (Centella asiatica Linn.), Yasthi madhu (Glycyrrhiza glabra Linn.), Guduchi (Tinospora cordifolia (Willd.) Hook. F. and Thomas.), Sankhpushpi (Convolvulus pluricaulis Chois) which are most common Medhya Rasayana mentioned in Ayurvedic samhitas, Nighantus etc
AYURVEDIC MANAGEMENT OF GENERALISED ANXIETY DISORDER - A CASE REPORT
Get PDFStress is a very common word that we hear in our custom. But when it becomes excessive, persistent and disruptive it becomes a trouble. Generalized anxiety disorder (GAD) is a common mental disorder that involves constant and chronic tension, worrying and nervousness. In India GAD has high prevalence of 5.8%. Compared to a panic attack, its intensity is less but chronicity is longer. GAD makes the person exhausted mentally and physically and makes problems emotionally and behaviorally affecting the quality of life badly because functional somatic symptoms in GAD shows a wide range. In Ayurveda, the symptoms of GAD shows characteristics of Chittodwega and indicates a very effective management.
A 25 year old male attended in OPD with increased tension, fear and uncontrollable anxiety, disturbed sleep, and stomach ailments, constipation, belching and reduced appetite. On interrogation it was revealed that he developed the symptoms over the last 2 years. Mental status examination was done. Considering the signs and symptoms, he was diagnosed with GAD.
Internally he was given with Somalatha Choorna, Aswagandharishta, Gokshura Choorna, Aswagandha Choorna and Sarpagandha Choorna to manage his anxiety and stomach ailments. Procedures done were Thala Pothichil, Snehapana, Virechana and Nasya to reduce his anxiety and other problems. During this time, he was also subjected to meditation and counselling techniques as well. The patient responded well to the treatment and his symptoms improved significantly. HAM-A scale score before treatment was 24 which was reduced to 6 after treatment. On discharge he was advised to continue the medicines and relaxation techniques. The Ayurveda protocol was found to be effective in managing GAD and highlights the importance of ayurvedic psychiatric treatments in similar conditions
Comprehensive Study of Mukhapaka and its Modern Counterpart
Get PDFOral hygiene is very important for everybody’s health. Mukhapaka (stomatitis) is the disease that spreads throughout the mouth. It is the inflammation of mucous membrane of lips, tongue, and cheek. It is common problems faced by all persons. Though, it may seem like a minor problem but it inhibits the daily activities. Stomatitis occurs due to hot, spicy and greasy foods, smoking, tobacco chewing, several drugs, infections, Vitamin B12 deficiency etc. Ayurveda has described four types of Mukhapaka: Vataja, Pittaja, Kaphaja and Raktaja. Different types of Mukhapaka have different types of symptoms. Pain relievers, mouth washes, lotions, corticosteroids, Vit. B12 are used to treat stomatitis. In present era, world is looking at Ayurveda for its valuable contribution in the treatment of any ailment. Sarvasara Mukharogas are named as Mukhapaka, as they diffusely spread in the Mukha (oral cavity)
Ayurvedic Approach Towards Wolf-Hirschhorn Syndrome: A Case Report
Get PDFWolf-Hirschhorn Syndrome is a rare chromosomal disorder caused by the partial deletion (structural aberration) of the short arm of chromosome 4. It is also known as 4P syndrome. The disease was first reported by Cooper, Hirschhorn and Wolf. The characteristic features of the patient depend on the extent of deletion of the genetic materials. The patient has craniofacial dysmorphism and the dysmorphic features are collectively known as Greek Warrior Helmet Facies. There is no direct correlation available for Wolf-Hirschhorn Syndrome in Ayurveda. Since it is a congenital pathology occurring due to chromosomal aberration it may be understood as a Sahaja vyadhi caused due to Beeja dosha. Here in this case the micro/partial deletion of genetic materials from short arm of chromosome 4 is due to the Beeja dosha that has occurred during the formation of Garbha (zygote). This Beeja dosha is responsible for the manifestation of different presentation in Wolf-Hirschhorn Syndrome which can be understood as a Vyadhi Sankara i.e., syndrome. The patient was presented with the features of facial dysmorphism, hypospadias, developmental delay and seizures. Hence the case was diagnosed as Vyadhija Phakka with Vataja Apasmara. In the present case the focus was mainly in the correction of developmental delay and to prevent the relapse of seizures. An integrated treatment protocol comprising Phakka chikitsa and Vataja Apasmara chikitsa were administered. Though there was no change in the facial dysmorphisms, but significant improvements were observed in the gross motor, language and communication milestones after the treatment
Recurrent Pregnancy Loss, Ayurveda - A Ray of Hope
Get PDFMotherhood is a dream of every woman. The fulfilment of this dream is a big challenge to clinicians and the couple, as many couple face problems in conception. The continuation of pregnancy after conception is also a challenge in present era. Pregnancy loss is often associated with physical, psychological and social deprivement. Couple becomes more depressive when there is recurrent pregnancy loss complicated with metabolic disorders. Here Ayurveda plays a very important role to combat with such ailments.
Methods: The patient was treated with Shodhana Karma followed by oral medications for 3 months.
Results: The patient conceived after 3 months of oral medication. She was under regular antenatal care and Ayurveda management throughout her gestational period. Pregnancy was uneventful till 35weeks 3days and delivered vaginally a healthy female baby of 2550grams
A Comparative Clinical Study on Effect of Agnikarma and Siravedha in Vata Kantaka w.s.r Plantar Fasciitis
Get PDFVatakantaka causes very severe pain in heal region. Vata gets aggravated and localised in Khudapradesha when person walks on unevenly or irregularly on surface. It causes difficulty to daily regular activities. It can be compared to Plantar Fasciitis as there will be stabbing (Kantaka) type of pain. Incidence is about 10% of the population, about 83% of these patients being actively working between age of 25-60 years. There is only conservative management for short term relief with certain draw backs and surgical management which increase hospital stay and high economical expenses. Acharya Sushruta described Agnikarma painful condition of Twak, Mamsa, Sira, Snayu, Asthi Sandhi. Sushruta also mentioned Siravedha of vein situated two Angulas (4cm) above the Kshipramarma in Vatakantaka. The study is aimed to compare efficacy of Agnikarma and Siravedha in Vatakantaka w.s.r plantar fasciitis. A total of 40 patients are selected and randomly divided into two groups, Group A Agnikarma in 20 patients and Group B Siravedha in 20 patients. Both group given relief in symptoms of Vatakantaka. Group A - Agnikarma (90.53%) and group – B Siravedha (88.31%) were significant in treating Vatakantaka. But Agnikarma is better effect then Siravedha in management of Vatakantaka. Both therapies can be done with less economical expenditure and minimum hospitalization