Ayushdhara (E-Journal)
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Evaluation of Antibacterial Activity of Hinguleshwar Rasa
Get PDFIn this era infectious diseases are posing problems for human beings. In order to avoid various infections, production and use of antibiotics is on rise. The widespread misuse of antimicrobials is responsible for emerging microbial resistance. Numbers of Ayurvedic classical preparations were being used in cases of infections, and they were found to be effective clinically. Therefore, to make our treatment scientifically more validated, we can assess the antimicrobial activity of such preparations in vitro (i.e., culture and sensitivity tests). The development of bacterial resistance to known antibiotics and adverse effect to presently available antibiotics has necessitated the search for new antibacterial agents in different systems of medicine. So Hinguleshwar rasa, a known traditional medicine, has been selected for this study. The antibacterial activity of the Hinguleshwar rasa was tested against pathogenic bacteria strain Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Salmonella typhi. In order to study antibacterial action of Hinguleshwar rasa in vitro well diffusion method. During this study Hinguleshwar rasa was trailed with bacteria at different concentrations. To correlate the result, control solutions were prepared by streptomycin. Experimental groups were compared with control groups and observations were noted
Role of Pathya-Apathya in the Management of Prameha (Type-2 Diabetes Mellitus)
Get PDFBefore starting management of any disease three important things to be kept in mind that is etiology, well planning, and Pathya-Apathya. Pathya–Apathya plays important role in the management of various disorders. Prameha is one of such disorder in which Pathya-Apathya affect its morbidity. Etiology, etiopathogenesis with clinical manifestation of Prameha are very well described in ancient textbook like Charaka Samhita, Sushruta Samhita, Astanga Hridyam and Astanga Samgraha etc. In all treatise of Ayurveda, Prameha is considered as Santarpanajanya Vikara that is of three types i.e., Vataj, Pittaj and Kaphaja. Madhumeha mentioned under the heading of Vataj Prameha that is closely correlated to diabetes mellitus. Diabetes Mellitus is of two type viz., Type-1 Diabetes & Type-2 Diabetes. Among that, Type-2 diabetes is non-insulin dependent diabetes mellitus that occur in middle age. In this clinical entity insulin resistance was developed. In its management, Pathya–Apathya contributes a major role in controlling blood sugar level. Therefore, author attempted to highlight role of Pathya–Apathya (do’s & don’t) in the management of Type-2 Diabetes Mellitus
Polycystic Ovarian Syndrome and Endometrial Receptivity Current Perspectives and Solution Through Ayurveda
Get PDFPCOS is a heterogeneous endocrine disorder which is characterised with oligomenorrhoea, anovulation, hirsutism and acne. Its prevalence increased exponentially from 2% to 18% in last two decades. On Later stages of its pathogenesis it manifests its metabolic involvement and causes various fertility issues and results into implantational failure which indicates endometrial defects. Conventional treatment includes combined oral contraceptives, insulin sensitizing drugs In alternative science various single herbs are mentioned which can reverse the pathology of PCOS and improve pregnancy outcome. So this review mainly rules out potential indicators for hampered endometrial receptivity and their solution through single herbs. Material and Methods: This is a literature review. Patient population is diagnosed cases of PCOS. This is a non interventional study. Data search was done from PubMed, Embase, and Cochrane Library. Conclusion: Patients with PCOS predisposed for endometrial receptivity disorder which can be cure with the use of single herbs via improved receptivity markers. Thus it helps to improve fertility and obstetrical outcome
An Experimental Study on the Analgesic Action of Padmak Agad
Get PDFPadmak Agad is indicated in all types of Luta and Keet Visha. According to Acharya Vagbhatta, heaviness in head and eyes, coma, dizziness, dyspnoea, pain, swelling, fever, itching and anorexia are common symptoms of all Keeta Damsha. Several synthetic and plant origin analgesic are being tested for their efficacy and potency on different animal model including hot plate, tail flick, tail clip, cold pain, filament pain, tail immersion technique, acetic acid induced writhing test, formalin induced writhing test etc. Material and Methods: Tail clip model and Hot plate model were selected for the present study. Eighteen Swiss albino mice had been divided in to three groups each group contain six mice. First group was negative control group; second group was test drug group while third group was standard group. Test drug was given to the group 2 for 7 days O.D. Result: When we performed the tail clip test, response time of group 1, 2, 3 were 4.40±1.853, 14.07±9.309, 40.68±11.759 seconds respectively. In Hot Plate model, calculated response time of group 1, 2, 3 were 2.93±0.667, 5.46±0.911, 6.04±0.857 seconds respectively. When we used Dunnett\u27s multiple comparisons test to compare the group 1 to group 2 and group 1 to group 3, there was statistically no significant role of test drug in tail clip model and hot plate model. Discussion and Conclusion: No effect of Padmak Agad is found in tail clip model. Padmak Agad is effective in hot plate model but not up to significant level
Pharmagonostical Analysis and Chromotographical Fingerprinting of Vajradanti (Potentilla fulgens (Wall.) ex Hook.)
Get PDFPoor oral hygiene or tooth disorders are very common and severely agonizing ailment leads to teeth loss or damaging of teeth, so it is the need of the hour to search for a potent drug which can fight this condition. Vajradanti is first described in Ayurvedic text Arka Prakash and Dravyagunakosha. Later in some Ethnomedicinal books Vajradanti is mentioned as potent medicine for Dantvikar, Udarshoola etc. Potentilla fulgens (Wall.) ex Hook. of Rosaceae family is an alpine medicinal plant that is found in temperate Himalaya between 2000-3000m. The root of the plant is of good medicinal value and has been used as folk remedy for treating ailments like diabetes mellitus, gastric problems, peptic ulcers, diarrhoea, cancer, toothache, pyorrhoea, cough, cold and also has anthelmintic property. A detailed pharmacognostical character of its root is not reported still yet. Methods: An attempt has been made to study the macroscopic and microscopic character, physicochemical analysis, phytochemical analysis, and chromatographic studies of its root following standard procedures. Two different extracts of Vajradanti root was used to access the physicochemical and HPTLC analysis. Research work was carried out as per standard operating procedures and specified protocols. Result: Results showed that in physicochemical evaluation aqueous extract 2.4%, hydro-ethanol extract 2.5%, total ash 8.6%, water soluble ash 1.38%, acid and insoluble ash 3.01%. HPTLC results for the quantification of epicatechin in EPF was analyzed for the first time by scanning at wavelength (λmax 366nm) and the quantity of epicatechin present in Vajradanti was estimated to be 0.032% w/w. In phytochemical analysis presence of carbohydrate, protein, glycosides, amino acid, protein in extract of Vajradanti. Conclusion: Vajradanti is a highly potent medicine for oral diseases due to presence of flavanols like epicatechin
Critical Analysis of the Concept of Rogamarga
Get PDFRogamarga is an important concept in Ayurveda that describes the mode of progression of a disease. Occurrence, progression and recurrence depend on the different Rogamarga that it follows. Through the description of three different Margas namely Bahya abhyantara and Madhyama, Acharyas have explained the entire pathway through which a Vyadhi occurs. Concept of compartmentalization deals with division of the body into different fragments as alimentary compartment, intravascular compartment, interstitial compartment and intracellular compartment. It is through the knowledge of these compartments that we understand the process of digestion and transportation of nutrients all over the body. The same concept can be utilized to understand the pathology behind a disease manifestation. Rogamarga as well as compartmentalization, both talk about pathway through which a disease gets manifested. It is important to know the pathway in order to understand the pathogenesis of a particular Vyadhi. Basic fundamentals of Rogamarga and compartmentalization find similarities. Each of the compartments can be categorized into the three Rogamargas Bahya Madhyama and Abhyantara at different levels. In our science though there have been studies and articles on the basics of Rogamarga much has been not explored regarding compartments and their role in disease manifestation. This article is a humble attempt to decode the concept of Rogamarga in terms of compartmentalization thereby trying to analyse the progression of disease pathogenesis
An Overview of Triphala Guggulu and its Ingredients
Get PDFTriphala Guggulu, a polyherbal Ayurvedic formulation, is among the most significant and frequently used Guggulu Kalpana. Numerous references for preparing this formulation have been mentioned in various classical texts. It has been discussed under ‘Vranashotha’ and ‘Vidradhi’ rogadhikar in Chakradutt and Yogratnakar respectively. ‘Triphala Guggulu’ presnted in this article is mentioned in the Sharangdhara Samhita under ‘Vati Kalpana’. As the name itself suggests, this preparation contains Triphala and Guggulu as the main ingredient along with Pippali. It contains Guggulu in greater proportion than the other ingredients, much like any other Guggulu Kalpas. Triphala Guggulu is frequently used in the treatment of Shotha, Arsha, Bhagandara, Gulma, Vrana, and other ailments. It can also be used as a hypolipidemic drug on its own or in conjunction with other formulations. Several studies and experiments have also demonstrated its efficacy in atherosclerosis, coronary and arterial plaque, and elevated cholesterol levels in the blood. Thus, this article takes the approach of reviewing the experimental research work done on Triphala Guggulu as well as covers the pharmacological action of its ingredients
An Ingenious Portrayal of Mythical Traits in Bala Graha
Get PDFBala grahas, are a group of organisms, very magnificent divine non human forms that have capability to invade human beings and cause diseases attaining different forms and shapes. Invisible organisms that seize children to cause various illnesses especially those with unrecognized causes can be categorized under the scope of Bala graha. Aim: A novel portrayal of the manifestations of Bala graha to bring in a better opportunity to realize their trait in a more impressing and fascinating manner. Materials and Methods: Bala graha having colossal dimensions cannot be encapsulated easily which paved to the necessity of ingenious portrayal of the same. The approach consisted of thorough searching of several resources which includes Ayurvedic treatises, books, dissertations, conference proceedings and web based scientific databases. The key words that were used for the search consists of Graha, Graha rogas, Bala graha, scientific approach to Bala graha, Bala graha and infectious disorders, pictures of Graha, images of Bala graha. Doing proper literary review revealed that there is sparse tries to enfold Graha rogas and the need to depict the same was considered Conclusion: Bala graha being the untouched and less explored sector of Kaumarabhritya, can be considered eccentric in its origin, invasion, manifestation and management and has very much similarity with infectious disorders. As Grahas attain different size and forms, the depth of the features they produce also varies in its mightiness. Having scrutinized the literature sufficiently arise the need for a new pictorial representation to encapsulate the enormous information regarding the subject matter. This can make the topic much easier to lay hold on and help to recollect the same proficiently
A Critical Review of Kala in Ayurveda
Get PDFKala is one of the nine Karana dravya. It possesses Kriya and Guna and is Nitya and Vibhu. It is understood by the occurrence of seasons, day, night, month, year etc. It gives the knowledge of past, present and future events. Kala plays its role from the birth to the death throughout the lifetime of an individual. The flowering, ripening, shedding of leaves in plants and other natural events are influenced by Kala. The Bhishak is referred as Kalavith. Methods: Kala or Time factor is explained in detail in Ayurveda literature from which important portions has been taken related with the study. Results: Available references on the study of Kala have been collected from the literature and information has been laid down to substantiate its importance in healthy and ill persons. Discussion and Conclusion: Kala is considered as a significant factor in the maintenance of healthy life in individuals and for an ill person the same Kala is understood as one of three causes for the disease condition. Time is continuously undergoing changes and a non-controlling entity because of which it is related to God
Review on Nilibhringadi Taila: An Effective Keshya Medication
Get PDFOne third of the population, including both men and women, experience hair problems, making it one of the most prevalent issues in the world. Both men and women in India are very sensitive about their hair. Numerous reasons, including hormone imbalances, stress, rising work pressure, poor dietary practises, and excessive use of chemical cosmetics, have contributed to a rise in cases of hair diseases and hair problems. Losing one\u27s hair can be embarrassing and detrimental to one\u27s confidence and self-esteem. Ayurveda provides some successful external hair management therapies. The pharmaceutics and therapeutics of Ayurvedic dose forms are quite specialised. Sneha Kalpana is a collection of medicated Taila and Ghrita that treat a wide variety of diseases in people of all ages. Sneha kalpas produced by Ayurvedic pharmaceutics are broadly utilised for both cosmetic and therapeutic purposes. It is the only Kalpana used in all four ways that these formulations can be administered: Pana, Abhyanga, Nasya, and Basti. In Ayurveda, hairs are referred to as Kesha, and medications that are effective for hairs are referred to as Keshya medications. In this article we have made an effort to describe the formulation Nilibhringadi Taila which is described in Sahasrayogam and Chikitsa Manjari. Nilibhringadi Taila is an Ayurvedic and herbal oil, which is useful to improve the quality of hair, to treat split hairs, premature greying and baldness. All ingredients in formulation are best hair growth promoters. It is widely used and prescribed formulation in India. Here not much more work has been done on this formulation. So we are trying to review this formulation for further knowledge and scope