Ayushdhara (E-Journal)
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Potential Role of Ayurveda in the Management of Maple Syrup Urine Disease
Full text linkMaple syrup urine disease (MSUD) is a genetically inherited metabolic condition that follows an autosomal recessive pattern. It results from malfunction in the branched-chain alpha-ketoacid dehydrogenase (BCKAD) complex, essential for the breakdown of branched-chain amino acids (BCAAs) such as leucine, isoleucine and valine. A defective BCKAD complex impairs the normal degradation of BCCAs, leading to their accumulation. This condition is marked by neurological and developmental issues, feeding difficulties, a distinctive maple syrup smell in the urine, including encephalopathy. Elevated blood levels of BCAAs and increased urinary excretion of their corresponding ketoacids are hallmark feature. When treatment begins early, individuals often experience positive clinical outcomes. Material and Methods- In this case, a 22-year-old male patient who a known case of hypertension, was brought by his parents with concerns of recurrent seizures occurring two to three times per week for the past 8 years, global developmental delay noted since infancy along with recurrent upper respiratory tract infections, salivary dribbling, excessive eating habit, irritable behaviour– since childhood. Associated with reduced sleep since childhood and masturbatory behaviour since 15 years of age. Patient was treated with Shamanaushadhi as a part of the management protocol. Results- This intervention led to substantial improvement in multiple aspects of the patient’s clinical presentation. Conclusion- The case indicates potential benefits of Ayurveda treatment in improving clinical outcomes and quality of life in an MSUD patient
Understanding Hridroga in the Light of Santarpana and Lifestyle Disorders
Full text linkHridroga is one among the serious life-threatening condition which affects Hridaya is due to the deranged Tridosha and the vitiation of Rasadhaatu. Hridroga is enlisted under Apatarpanottha Vikaras. When we look into the Nidanas of Hridroga, most of them point towards features of Apatarpana meaning undernourishment or depletion. Metabolic syndrome is an asymptomatic pathophysiological condition characterized by central obesity, high blood pressure, insulin resistance, dyslipidemia and hyperglycemia. In the present era, the pattern of cardiovascular disorders has shifted, with increasing prevalence linked to sedentary lifestyle, over-nutrition, obesity metabolic syndrome that are characteristic of Santarpana. This study is an attempt to reinterpret and derive Santarpanottha Nidānas that may lead to Hṛidroga, aligning classical concepts with modern clinical presentations
Effect of Nitya Virechana in Madhumeha Using Trivrit Kwatha
Full text linkMadhumeha, one of the twenty types of Prameha described in Ayurveda. It is a chronic metabolic disorder characterized by impaired carbohydrate, fat, and protein metabolism leading to hyperglycemia and multiple systemic complications. Classical Ayurvedic texts emphasize the role of Shodhana Chikitsa (purificatory therapies) in the management of Madhumeha to correct the deranged Doshas and to improve Agni and Srotoshuddhi. Among these, Nitya Virechana (daily purgation) is considered effective for eliminating vitiated Pitta and Kapha while regulating Apana Vata. This case report presents the management of a 44-year-old male patient diagnosed with Madhumeha who exhibited classical clinical features such as Prabhuta Mutrata (polyuria), Naktamutrata (nocturia), Vibandha (constipation), Atinidra (excessive sleep), Swedadhikya (excessive sweating), Daurbalya (weakness), Kshudhadhikya (polyphagia), and Karapada Daha (burning sensation in palms and soles). The patient was administered Nitya Virechana with Trivrit Kwatha (decoction of Operculina turpethum) daily for 21 days. Regular clinical monitoring and assessment of glycemic parameters were carried out during the intervention period. At the end of therapy, the patient demonstrated significant improvement in glycemic control along with marked relief from associated symptoms such as constipation, excessive sleep, weakness, and burning sensation. The therapy was well tolerated without adverse effects. This case highlights the potential role of Nitya Virechana with Trivrit Kwatha as an effective supportive Ayurvedic intervention in the management of Madhumeha. It emphasizes the importance of Ayurvedic Shodhana measures in addressing the metabolic derangements of diabetes and improving quality of life
The Role of Brahmacharya (Tryaupstambh) in Health Promotion: A Systematic Review of Ayurvedic Principles and Contemporary Research
Full text linkBrahmacharya, one of the three fundamental pillars of Ayurveda (Tryaupstambh), is traditionally regarded as the disciplined practice of self-restraint, particularly in sexual behavior, to preserve Ojas, maintain Agni, and promote overall health. With the rising prevalence of lifestyle-related disorders, Brahmacharya has attracted renewed scientific interest. This systematic review analyzed classical Ayurvedic literature alongside modern experimental studies, clinical trials, and systematic reviews up to August 2025, sourced from PubMed, AYUSH Research Portal, Scopus, Web of Science, and authenticated classical texts. A total of 35 studies were included, revealing that Brahmacharya positively impacts hormonal balance, oxidative stress, cognitive function, psychological well-being, reproductive health, and metabolic parameters. Clinical trials demonstrated improvements in sperm quality, menstrual regularity, BMI, glucose tolerance, and mental health outcomes. However, the evidence is limited by heterogeneous study designs, small sample sizes, short durations, lack of standardized protocols, and insufficient mechanistic investigations. This review concludes that while Brahmacharya shows potential as a holistic preventive and therapeutic practice, further rigorous, large-scale randomized controlled trials and long-term studies are needed to establish standardized methodologies and validate its clinical efficacy
A Comprehensive Review of Vidangadi Churna and its Role in Ayurvedic Medicine
Full text linkAyurveda, the ancient Indian system of medicine, adopts a holistic perspective on health, emphasizing the balanced integration of body, mind, and spirit. Among its major disciplines, Bhaishajya Kalpana (Ayurvedic pharmaceutics) is concerned with the formulation, preparation, and quality assurance of medicinal products. Within this field, Churna Kalpana refers to herbal formulations in powdered form, which are widely appreciated for their ease of administration, fast absorption, and long shelf life. In Ayurvedic understanding, Krimi Roga encompasses diseases caused by internal and external parasites, often resulting from unclean habits, poor dietary choices, and lifestyle imbalances. To manage such conditions, classical texts recommend Vidangadi Churna- a traditional polyherbal preparation, with Vidanga (Embelia ribes) as its principal component. This formulation includes herbs with Krimighna (antiparasitic), Deepana (digestive stimulant), and Pachana (carminative) properties, aimed at eradicating intestinal parasites, strengthening digestive fire (Agni), and preventing recurrence. By supporting detoxification and enhancing digestive function, Vidangadi Churna showcases the therapeutic potential of Ayurvedic interventions in managing parasitic disorders. Scientific validation and standardization of such classical formulations can enhance their credibility and set the stage for their integration into modern evidence-based healthcare systems
Understanding Conceptual Frame Work on Preventive Aspect of Rakta Dusti in Sarad Rtu
Full text linkRitucharya is a concept in Ayurveda, one has to adapt diet, lifestyle etc based on different seasonal variations. To prevent Rakta Duṣṭi (haematological disorders) following Rtucaryā is essential, especially during Śarad ṛtu, when Pitta aggravates and impacts Rakta due to their mutual relationship. The vitiation of blood during this season can lead to disorders, emphasizing the need for understanding preventive measures from Ayurvedic texts for further research. This paper discusses about Rakta Duṣṭi and its prevention in Ayurvedic medicine, utilizing information from databases like the AYUSH Research Portal and PubMed, as well as classical texts. Rakta Vaha Srotodushti refers to the disruption of blood vessels caused by the consumption of hot, oily and liquid foods as well as excessive exposure to heat from the sun and fire. Acharya Sushruta classifies Rakta dushti into Vataja, Pittaja, Kaphaja, Sannipataja and Dwidoshaja each associated with specific symptoms and diseases. Notable conditions related to Rakta dushti include Pandu Roga, Dāha, and Jwara. The pathophysiology reveals that disorders like Mada, Mūrchchā and Sannyāsa arise from improper dietary habits and obstructed Srotas. Seasonal influenza, caused by influenza viruses A and B, exhibits region-specific seasonal peaks in India and presents symptoms that align with Ṛtuvyāpad, while the observed Raktaduṣṭi in influenza is evident from hematological changes like altered Neutrophil/Leucocyte ratios. Preventative measures include adhering to Sharad Ritu Carya
Contemporary and Ayurvedic Therapeutic Strategies in Colorectal Cancer: A Systematic Review
Full text linkColorectal cancer (CRC) remains one of the most prevalent malignancies worldwide, contributing significantly to cancer-related morbidity and mortality. Although survival rates have increased because of modern therapeutic approaches such surgery, chemotherapy, radiation, targeted therapy, and immunotherapy, but problems like toxicity, expense, resistance, and recurrence still exist. At the same time, Ayurvedic treatment provides a comprehensive framework that emphasizes herbal remedies, nutrition, lifestyle, Dosha balance, and detoxification (Panchakarma). The mechanical justification, preventative and supporting functions, and integrative care prospects of contemporary and Ayurvedic approaches to CRC management are all examined in this systematic review. In order to maximize patient outcomes, the review emphasizes the significance of fusing traditional Ayurvedic principles with evidence-based modern oncology
Role of Shunthi Bilva Kwatha with Yava Saktu in Garbhini Chhardi (Emesis Gravidarum)
Full text linkGarbhini Chhardi, or pregnancy related nausea and vomiting, is a common problem that causes discomfort, dehydration, and digestive issues in many pregnant women. This article discusses how Shunthi bilva kwatha with Yava saktu can help manage this condition through an Ayurvedic approach Zingiber officinaleis (dry ginger) and Aegle marmelos (Bilva) known for its Vata-balancing, digestive-stimulating, and appetite-improving properties. These actions help regulate Vata dosha, support the digestive system, increases the Agni and reduce feelings of nausea. Hordeum vulgare (roasted barley) has thirst-relieving and Kapha-reducing qualities. It helps control excessive thirst and balances Kapha, both of which are commonly linked to nausea and vomiting during pregnancy. The article highlights how these two ingredients work together to give better relief from Garbhini Chhardi (vomiting during pregnancy). Their combined effect helps tackle the root causes by supporting digestion, balancing the Doshas and keeping the body hydrated. Because of this, the remedy helps reduce both how often vomiting happens and how strong it feels. Along with that, this mixture is easy to take and fits well into the busy routine of today’s expecting mothers. Overall, this Ayurvedic combination offers a safe, natural, and effective way to manage pregnancy-related vomiting, helping ensure comfort and well-being for both the mother and the baby In Ayurveda Acharyas have advised that the patient’s provided numerous formulations for addressing Garbhini Chhardi This study evaluates the effectiveness of Shunthi Bilwa Kwath Combined with Yava Saktu in managing this condition
Rasayana and its Importance in Ayurveda
Full text linkRasayan Tantra is one of the most important branches of Ayurveda. It helps to delay the ageing process, helps to provide good strength and offer excellent immunity from various infections. It also maintains good digestion, metabolism, cardiac and mental health. Rasayan science also deals with measures, medicines, treatments which bring about delay in ageing process and also helps in the maintenance of health in old age, apart from providing strength and immunity. Rasayan help in the formation of best quality Dhatus/tissues and also support the channels which help in the formation and transportation of tissues and also the nutrition needed to form these tissues from one place of the body to the other. These medicines delay the ageing process by reducing the oxidative stress in the cells of body and central nervous system, thereby promoting the longevity and disease-free body. Rasayana have broad spectrum role as they are anti-inflammatory, anti-cancer, hepatoprotective, renoprotective, neuroprotective, cardiotoic and are excellent immunomodulators. They can be co-related with anti-oxidants in Western Medicine
Evidence Based Ayurvedic Approach in the Management of Dysfunctional Uterine Bleeding
Full text linkAbnormal uterine bleeding without intrinsic pathology is the hallmark of Dysfunctional Uterine Bleeding (DUB), a frequent gynaecological issue. Because of the vitiation of the Vata and Pitta Doshas, which affects the Artava Vaha Srotas, Ayurveda associates these diseases with Asrigdara or Raktapradara. Main Clinical Finding: A 37-year-old female patient presented with ultrasonography (USG) suggestive of Thickened endometrium with polycystic ovaries. The case was treated for 3 months with a combination of different Ayurvedic drugs to reduce symptoms and cure DUB. Diagnosis: The patient consulted the Ayurvedic OPD of M.M.M. Govt. Ayurveda College & Hospital Udaipur, with the complaint of heavy and prolonged menstrual bleeding, short cycle and generalised weakness since last 4 months. Her USG revealed thickened endometrium with polycystic ovaries and CBC revealed low haemoglobin. Interventions: This DUB patient received treatment with traditional Ayurvedic formulations, such as Shunthyadi churna taken orally and Matra basti with Shatavari Taila 60ml in follicular phase for three consecutive menstrual cycles with addition of Pathya-Apathya. Outcome: Investigations conducted after therapy revealed improvements in hemoglobin levels, endometrial thickness and clinical outcomes. Conclusion: This case demonstrates the potential of Ayurvedic therapy in managing DUB without hormonal intervention