International Journal of Ayurveda and Pharma Research
Not a member yet
2276 research outputs found
Sort by
Prevalence of Vitamin B12 Deficiency in Type 2 Diabetes Mellitus
Full text linkVitamin B12 named as Cobalamin a water-soluble vitamin plays significant role in several biological process such as DNA synthesis, Neurological function, and Optimal Haemopoiesis etc. The deficiency of vitamin B12 affects a number of processes, including the methylation of homocysteine, nucleoprotein, myelin production, DNA synthesis, lipid and glucose metabolism, and others. Vitamin B12 deficiency is a potential comorbidity that is often overlooked, but puts many diabetic patients at risk of developing particular complications. Various research showing an association between type 2 diabetes mellitus and a vitamin B12 deficiency. The purpose of the study is to find out the prevalence of vitamin B12 deficiency in Type 2 diabetic patients. 200 subjects of Type 2 diabetic patients were studied over a period of six months from August 2023 to February 2024 in the OPD of Kaya Chikitsha, Department of Ayurveda, IMS, Banaras Hindu University, Varanasi. Results: The present study summarizes that the prevalence of vitamin B12 deficiency in T2DM patients were 19% and 36% of respondents has borderline vitamin B12 level. The results also shows that the majority of male were having the deficiency of the vitamin B12 level as compare to the females. Study also shows the association of age and the vitamin B12 level (p<0.05)
Development and Standardization of Ellumthippallyadi Lehya Candy
Full text linkEllumthippallyadi Lehya is one among the classical lehya formulation mentioned in sahasrayogam. Lehya formulations are often sticky, dense, and may have a strong odor, which can be unappealing, especially for sensitive individuals. Dosage accuracy can also vary with difference in consistency. Candies, though primarily consumed for taste and pleasure are increasingly being explored for their potential as carriers for therapeutic agents. Development of new dosage forms and ensuring their quality and safety through pharmaceutical standardization is essential for their acceptance especially in health focused formulations. Ellumthippallyadi Lehya Yoga was converted to a candy as a modified dosage form with a uniform weight of 3g. Machinery support was used for the production of candies. The drugs were taken in the ratio as mentioned in the reference. The constituents in one candy were adjusted considering the amount of Loha bhasma as 50 mg in each candy. The candies were made using palm sugar candy as base and liquid glucose was added for desired consistency. Elluthippallyadi Lehya Candy was subjected to standard pharmaceutical evaluations, including organoleptic properties, weight variation, and Disintegration time, pH, and heavy metal analysis using standard methods. The Ellumthippallyadi Lehya candy demonstrated compliance with standard pharmaceutical parameters and its other safety parameters ensured its potential as a convenient dosage form
Resolving Azoospermia (Shukra Kshaya) with an Ayurvedic Approach
Full text linkAzoospermia, characterized by the absence of sperm in the ejaculate, is a significant contributor to male infertility. Traditional treatment approaches often combine hormonal therapies, surgical interventions and assisted reproductive techniques, yet not all cases resolve successfully. This paper explores a treatment approach using Ayurvedic therapies. The study focuses on a 37-year-old male diagnosed with azoospermia, initially presented with the symptoms of sleeplessness, fatigue and general weakness. The patient underwent a treatment regimen including Ayurvedic formulations over a period of six months.
Post-treatment evaluations revealed significant improvements: total sperm concentration increased from nil to 28 million/ml, progressive motility improved to 50%, and sperm morphology normalized with 96% of sperm showing normal forms. Subjective symptoms also showed remarkable improvement with the Insomnia Severity Index score reducing from 18 to 8, and the Fatigue Severity Scale score reducing from 45 to 25. These findings suggest that integrating Ayurvedic medicine with conventional treatments can effectively enhance fertility outcomes and overall quality of life in patients with azoospermia. The study advocates for further research through larger clinical trials to validate and potentially standardize this integrative treatment approach
Literature Review of Shati in Various Ayurvedic Treatise
Full text linkHedychium spicatum Ham.ex Smith, commonly known as Kapur Kachari or Shati is one of the highly valued rhizomatous herb useful in a wide range of diseases. The rhizomes of this plant give a stimulant effect on the respiratory system. In Ayurveda it is considered as a potent herb to cure diseases like cough, symptoms of cold, asthma, bronchitis. It is placed under Hikka Nigrahan and Swashara Gana. The Guṇa-Karma of Shati included Laghu, Teeksṇa, Guṇa; Kaṭu, Tikta, Kaṣhaya Rasa; Anushṇa Veerya. Shati was found to be as the ingredient of many formulations like Chawanprasha, Agastya Haritaki Rasayana, Mahamayur Ghrit and Sudarshana Churna and used in the treatment of cough, hiccough, fever and asthma and other respiratory problems. The rhizomes are considered useful as stomachic, carminative and stimulant for the treatment of liver disorders, food poisoning, inflammation, asthma pain, bronchitis and brain tonic. Various Paryaya, Guna, Karma and different opinions of Acharyas from various Samhitas were observed
Asphaltum Punjabianum (Shilajit): Unraveling Myths with Scientific Evidence
Full text linkShilajit is a mineral-rich resin that has a long history of use as a rejuvenator (Rasayana) in Ayurvedic medicine to treat various ailments such as arthritis, infertility, and cognitive decline. Although it is becoming increasingly popular, with more scientific validations, many myths still surround its actual clinical potential. This review directly debunks several persistent myths about Shilajit based on a critical evidence-based analysis. Among the key myths addressed is the notion that only men should take Shilajit, that it is solely a sexual health enhancer, that it works acutely, and that its supplements can be contaminated, rendering them inherently unsafe or unnatural. According to scientific sources, Shilajit is beneficial for both men and women, and it has been proven to contribute to bone health, metabolic processes, antioxidation, and cognitive enhancement. Rather than acting as an acute stimulant, Shilajit functions more as a slow-acting adaptogen that must be taken continuously over several weeks to produce observable physiological adaptations. It is also well-tolerated even in very high doses, as indicated by its toxicological and clinical safety data, provided it is purified. The concerns regarding contamination are addressed through purification, with the majority of certified products meeting global safety standards. Secondary myths, including the belief that Shilajit causes constipation, is inadvisable to use in summer, or leads to kidney stones, are also disproven by clinical and preclinical evidence. Ultimately, one can conclude that Shilajit is an effective and safe multilateral nutraceutical with diverse therapeutic potential. This review advocates for its incorporation into modern healthcare through science-based, myth-busting integration and challenges clinicians to base their recommendations on usage grounded in empirical evidence and quality assurance
Management of Vatakantaka w.s.r to Calcaneal Spur by Agnikarma
Full text linkObjectives: In today’s day to day life, prolonged hours of standing, poorly fitted and hard sole footwear, excessive walking, running and being overweight, they all are the risk factors of the calcaneal spur. There is no proper treatment in modern medicine other than surgery but Ayurveda offers a variety of treatment procedures through which patient can get relief. One of the most effective methods is Agnikarma. In Ayurvedic texts, similar signs and symptoms are found in a Vatavyadhi named Vatakantaka. Thus, Vatashamak chikitsa becomes the basis of the treatment. Materials and Methods: An attempt has been made in which 5 patients with calcaneal spur, confirmed by X-Ray having main complain of pain and tenderness in heel region were taken under study and Agnikarma were done for consecutive 3 weeks (once a week). Result: After the therapy, patient feels instant relief in the pain. Conclusion: This proves that the Agnikarma plays a very effective role in the management of calcaneal spur
Efficacy of Guduchyadi Yoga in the Management of Medoroga with special reference to Dyslipidemia- A Rondomized Clinical Trial
Full text linkMedoroga, a condition which arises due to Medo dhatu vriddhi which may lead to Bahutwa and Abaddhatwa of Poshaka medo dhatu. It can be correlated to disease dyslipidemia based on pathophysiology. It is the need of the hour to contribute safer, effective and economical medicines to manage the condition. Main aim of the study was to evaluate the efficacy of Guduchyadi yoga and Navaka Guggulu in the management of Medoroga with special reference to dyslipidemia. Methods: The present study implemented an open-labelled, active controlled pre and post-test clinical study with 30 subjects (who fulfilled the diagnostic and inclusion criteria). A convenience sampling method was used for the selection. Subjects were randomly assigned into two groups, Group A (trial) and Group B (control) comprising of 15 subjects each. Subjects of Group A received Guduchyadi Yoga (50ml Kashaya with 1.5g of Guggulu) and Group B received Navaka Guggulu (2 tablets with warm water). Both interventions were given twice daily before food for duration of 30 days. A twelve-hour fasting sample of serum lipid profile and BMI were used to measure the efficacy before and after the treatment. Statistical analysis of parameters was assessed using Wilcoxon signed rank test (W), Friedman’s test, Mann Whitney U test (U), by paired t-test, repeated measures ANOVA test, unpaired t-test. Results: The trial drug showed statistically significant result in improving serum lipid profile and reducing BMI (P<0.05). Conclusion: The polyherbal formulation (Guduchyadi yoga) is effective in the management of Medoroga (dyslipidemia)
Role of Jalauka Avcharana and Ayurvedic Management in Dadru Kushtha
Full text linkA massive increase in incidence of skin problems can be seen in tropical and developing countries like India. Dadru (Tinea corporis) is one of the most encountered skin diseases occurring due to unhygienic conditions, poverty, poor sanitation, sun exposure etc. Dadru is described under Kshudra kushtha in Charaka Samhita, which if left untreated it seeps into deeper tissues and becomes difficult to cure. For present study, a male patient of 15 yrs age visited department of Shalya tantra at Uttarakhand Ayurved University Gurukul Campus Haridwar with complaint of widespread patches and severe itching over back side of neck from 6 months. He also had on and off constipation from 15 days, disturbed sleep for 2 months and loss of appetite. There was no significant past history of any other chronic disorder. The patient was diagnosed with Dadru kushtha (Tinea corporis) on the basis of clinical symptoms and investigations. Patient was treated with Ayurvedic para surgical process (Jalaukavchran) along with oral Ayurvedic medicines like Arogya vardhni vati, Nimbadi churna, Gandhak bhasma, Trikatu churna, Khadirarishta, Triphala churna for 45 days. A significant response was observed over clinical symptoms, healing and recovery of Dadru
Application of Loka Purusha Satmya Vada in Treating Filiform Wart
Full text linkWarts are cutaneous neoplasms caused by papilloma virus. Human papilloma viruses infects the epithelium of skin and mucous membranes. These infections may be asymptomatic, produces warts or may produce neoplasia. Filiform warts usually appear around the mouth, nose, under the chin or neck. They are long, narrow frond like benign growths. Even though these growths are asymptomatic they create a lot of cosmetic concern. In appearance these warts resemble sprouts coming from potatoes. Loka purusha Satmya vada told in Ayurveda classics tells us the relationship between universe and the humans. Thus the similarity in shape of filiform warts with potato sprouts tells the hidden remedy for these warts. Here the antimicrobial activity in potatoes was applied in treating the patient along with krimihara chikitsa
Role of Shleshmatakadhya Agad in the Management of Dushi Visha
Full text linkAyurveda is an ancient science that aims to maintain the good health and to cure the diseases and pathological conditions of human beings. Agad tantra is a branch of Ayurveda that deals with the Visha (poison), its associated symptoms along with its Chikitsa (management). In Agad tantra, concept of Viruddhahara (incompatible food/diet), Gara Visha (concocted poison) and Dushi Visha (denatured/latent poison) has been explained in detail that contributes to the leading reasons for the occurrence of toxicity related disorders or disease. Most of the diseases are caused due to unconventional etiology for which Agad tantra comes into focus. To combat the poisonous effect, various Agad Yogas are mentioned in Visha Chikitsa grantha to counteract all types of poisons (Sthawara, Jangama, Kritima visha, Gara visha, Dushi visha). Shleshmatakadhya Agad is one of the Yoga mentioned in Yogaratanakar as a Sarva- vishanashanam under Visha Chikitsa. Shleshmatakadhya agad contains Shleshmatak, Apamarga, Guduchi, Nripdruma, Kantakari and Brihati. This article highlights the role of Shleshmatakadya agad, an antitoxic formulation to conquer diseases due to unconventional etiology in current scenario