International Journal of Ayurveda and Pharma Research
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    DETAILED STUDY ON THERAPEUTIC PROPERTIES, USES AND PHARMACOLOGICAL APPLICATIONS OF SAFFLOWER (CARTHAMUS TINCTORIUS L.)

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    Safflower (Carthamus tinctorius L.) belongs to the family Asteraceae. Safflower has been grown mainly for orange-red dye (carthamin) extracted from its flower used in food coloring and flavoring. Safflower seed oil is highly rich in linoleic acid (unsaturated fatty acid) which makes it highly suitable for human consumption. The whole plant of C. tinctorius possesses many pharmacological activities like antifibrosis, antidiabetic, antitumour, anti-inflammatory, hepatoprotective, antihperlipidemic, anticoagulant, and antioxidant activities. Regardless of it numerous uses, this crop is under the category of minor and neglected crop, therefore additional research work is required for its commercialization. The present review critically deals with botanical description, distribution, classification, uses, pharmacological activities and chemical constituents present in safflower

    DESHA VIRUDDHA IN DIFFERENT REGIONS OF INDIA

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    Ayuveda is blended with lots of Siddhantas. Among them Viruddhahara is one of the most imperative and well-known Siddhant. In Viruddhahara, Samyoga-viruddha and Virya-viruddha are the most familiar and emphasized frequently. Rests of the Viruddhas are remain untouched or not highlighted to that extend. Man has natural tendency towards change in the life at every stage hence the food and food habits are also covered by this tendency. Although some groceries are precise to specific region and people take that foodstuffs unknowing which may not be good for an individual health. These kinds of food one can be included in Desha-viruddha. As every state is having different regional diversity and also the diversity of their food habits, hence it is very difficult to conclude Desha Viruddha according to intake of foodstuff at regular base. But then also the efforts have been put here to state various Desha Viruddha according to various regions along with their mode of action

    IN VITRO ACCUMULATION OF CADMIUM CHLORIDE IN PAPAYA SEEDLING AND ITS IMPACT ON PLANT PROTEIN

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    Background: Carica papaya has wide range of applications in traditional medicine. It has high nutritional content and various medical applications. Objectives: In the present study, changes have been observed at the morphological, biochemical, antioxidation and protein level in Carica papaya L variety Pusa Dwarf by accumulation of cadmium chloride in vitro. Material and methods: Plants were treated with different concentrations (20ppm, 40ppm, 60ppm and 80ppm) of cadmium chloride, and examined changes in growth and protectively induced oxidative stress in relation to heavy metal in three weeks old seedlings. Protein profiling by SDS-PAGE was done to study the influence of severe heavy metal stress in Carica papaya L. variety Pusa Dwarf leaf and root explants. Result: Plant seedlings showed decrease in morphological characteristics like plant height, root and shoot length in response to increasing concentrations of heavy metal stress. Similarly carbohydrate content decreased in both leaves and roots while chlorophyll pigments (a+b) increased in leaf explants. Proline and polyphenolic compounds showed an increase in stressed plants compared to control. Conclusions: Plants undertake many adaptive mechanisms for their survival under metal stress which includes morphological as well as biochemical characters. Proline and polyphenolic compounds indicate the presence of excellent antioxidative ingredients to protect the induced by free radicals. Plant protein profiling supports the effect of heavy metal stress in papaya

    COMPARATIVE STUDY ON CHARAKA NIDANA STHANA WITH OTHER CLASSICS

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    Among all the available classics, the most ancient representative of Kaya Chikitsa is Charaka Samhita. It is not only a text book it is an ideal ancient treatise based on eternal fundamentals and basic principles. Charaka Samhita consists of eight diseases in Nidana Sthana. All the classics gives importance to Nidana because it is a Sarva Tantra Siddantha that, the effect will always going to imitate the cause i.e. Karya Karana Bhava. Before understanding Chikitsa the knowledge of nidana is very necessary and for all disease. The main line of treatment is Nidana parivarjana and to get the clear knowledge of disease one should know about the Nidana panchaka, which is explained in Nidana sthana. Diagnosis is never complete without the elicitation of all the factors associated with the diseases. Aims and Objectives: To enlighten the basic concept of framework of Nidana sthana to its full perspective and the importance to the specific concept as well as the number of chapter given in Nidana sthana. Materials and Methods: In this study classical Ayurveda text were thoroughly studied where the compilation has been done. Discussion: compiled all the information of Nidana sthana and critically analysed in aspect of content and chapters of each Nidana sthana of different classics. Elicitation of Nidana is necessary for the proper identification of Dosha, the Roga, Rogavasta, Roga Bala, and Sadhya Asadhya. Result: Charaka nidana sthana is provides the basic fundamental concept to all other classics. Nidana sthana gives the draft of many pathogenesis. The other classics elaborated the Nidana panchaka concept in very detail manner

    A REVIEW ON CLINICAL EXAMINATION OF AGNIBALA (DIGESTIVE POWER)

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    Ayurveda, the science of life mainly deals with the preventive aspect of diseases along with curative aspect and this is the aim of Ayurveda. For that prevention purpose life style modification is very much essential now a day. Some factors are responsible for the formation of a disease among of them Agni is one of the most important factor. Agni plays an important role to sustain the life process. All the diseases are caused due to impaired function of Agni. According to modern science, Gastric juice and enzymes functioning at gastro intestinal level, all are responsible for digestion, absorption and metabolism. Altered function of the enzymes secreted from gastro intestinal tract is responsible for production of gastro intestinal diseases. Function of Agni is likely to be compared with gastric juice and different enzymes at gastro intestinal level. In the present era, the diseases related to Annavaha srota and Purishvaha srota (Gastro intestinal system) are commonly found in clinical practice. In the pathogenesis of disease, Dosha, Dusya, Srota, Agni and Ama (Prime causative factors of diseases) are required to be analyzed for fruitful treatment. In present study center of attention has given on clinically evaluation of Agnibala (Digestive power) based on Ancient classical theory

    SCIENTIFIC STUDY ON RAKTA DHATU AND ITS RELATED DISORDER AND EFFECT OF VARNYA MAHAKASHAYA GHANVATI AND CHANDRA PRABHA LEPA IN THE MANAGEMENT OF YUVAN PIDIKA (ACNE VULGARIS)

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    Due to increased competition of earning prosperity in today era human adopted not only lifestyle but also food habits of western culture which is chiefly responsible to derangement in their physiology and responsible to number of skin disorder like Yuvan pidika (acne vulgaris). In Ayurveda vitiation of Vata, Kapha and Rakta are etiological factor that give rise to Yuvan pidika. That is why there is a need of such treatment that contains Vata kapha shamaka and Raktasodhaka property. For this Varnya Mahakashaya Ghanvati and Chandra Prabha lepa were selected for the study on 30 registered patients. Both of these were formulated compound. Varnya Mahakashaya Ghanvati was advocated to patient in a dose of 800 mg twice daily for 60 days while Chandra Prabha lepa was locally applied by making paste with Gulab jala. This study shows highly significant result to ameliorate the symptom of Yuvan pidika especially on Vata dosha pidika as well as Kapha dosha pidika. Both these drugs proved their efficacy to manage Yuvan pidika by making homeostasis of Vata, Kapha and Rakta

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