International Journal of Ayurveda and Pharma Research
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Probable Mode of Action of an Indigenous Drug Formulation in Garbhini Pandu wsr Iron Deficiency Anemia
Get PDFPregnancy marks a significant milestone in a woman\u27s life, transitioning her from a woman to a mother. While it is a joyous journey, it brings about numerous physical and physiological changes that can lead to certain health challenges. Iron deficiency anemia is a prevalent health concern during pregnancy, particularly widespread in developing nations, necessitating urgent intervention to safeguard the lives of both the mother and the child. About 4 to 16% of maternal deaths are due to anemia. In contemporary science, to prevent complications like maternal and fetal mortality and morbidity, increased risk of infection, spontaneous abortion, intrauterine growth retardation, intrauterine death, premature delivery, low birth weight, postpartum hemorrhage etc during antenatal and postnatal period, various haematinic drugs are prescribed from 3rd month onwards. In Ayurveda this condition is considered as Garbhini Pandu. The Rasa and Rakta of the mother are carried to the fetus for its proper growth and development. If not, it leads to Rasa dhatu kshaya in Garbhini which finally leads to Garbhini Pandu. Ayurveda highlights the contradiction of Shodana in pregnant ladies, hence Shamana chikitsa can be followed judiciously. Considering the necessity of utilizing a safe and beneficial drug for Garbhini Pandu during pregnancy, certain indigenous drugs such as Agasthya, Amalaki, Draksha, Musta, Pippali, Sigru, Shuddha Kasisa, and Bhavana dravyas like Dadima, Bhringaraja, and Mandukaparni have been incorporated. This article highlights about the probable mode of action of indigenous drug formulation in Garbhini Pandu
Effect of Vyaghri Haritaki Lehya in Chronic Tonsillitis in Children of the Age Group 3-12 Years
Get PDFTonsillitis is the inflammation of the tonsils. The tonsils are two small glands on either side of the throat. The tonsils play a key role in helping the body to protect against infection. This is especially in young children, whose immune system is still developing. The tonsils act as a barrier, trapping an infection and stopping it spreading to other parts of the body. In Ayurveda tonsillitis is correlated with Tundikeri, the disease of Talu (palate) and Kantha (throat), both of which are the Avaranas (establishment) of Mukharoga (diseases of mouth). Although no specific formulation for Tundikeri is given and surgical treatment is described for the disease, many formulations for Mukharogas (mouth disorders) are effective in Tundikeri. Vyaghri haritaki lehya is described by Bhaishajya Ratnavali and Chakrvadatta. It is also included in Bhava Prakasha, Yoga Ratnakara, Gada Nigraha, Vanga Sena samhita and Bharat Bhaishajya Ratnakar. A case study of 20 children on chronic tonsillitis done using Ayurveda medicine to improve general health.. Internal administration of Vyaghri haritaki lehya, the dose was 5gm for children between 3 to 6 years and 10gm for children between 7 to 12 years with lukewarm water as adjuvant, for a period of 60 days given. Follow up done after a period of 30 days
Effect of Mamsyadi Kwatha along With Structured Satvavajaya Module in the Management of Post Stroke Mood and Emotional Disturbances - Single Group Pre-Test Post-Test Design
Get PDFStroke is considered as one of the major causes of physical disability which has a serious impact on mental health and affecting the quality of life (QoL) of an individual. This study is intended to explore the effect of Mamsyadi kwatha along with structured module for addressing the psychological problems of stroke survivors and to measure its effects on improving the issues like depression, anxiety, anger proneness, fatigue, emotional incontinence and quality of life in them. Mamsyadi kwatha with proven efficacy in anxiety and depression was selected with the structured Satvavajaya module and administered in 21 participants. The participants were in the age group of 30-75 without any history of psychiatric illness and recent stressful life events or trauma and those who can communicate properly were recruited for the study. Mamsyad kwatha and Satvavajaya module were administered for initial 14 days. Assessments were done on 0th day/ 7th day/ 15th. Main outcome measures included emotional problems like depression and anxiety, fatigue, emotional incontinence, anger proneness and stroke related QoL. After the treatment, significant improvements were noted in depression (p<0.001), anxiety (p<0.001), anger proneness (p<0.001) and in majority of the domains in SSQoL (p<0.001)- quality of life
Therapeutic Effects of Glycyrrhiza Glabra Linn.
Get PDFGlycyrrhiza glabra Linn. (Licorice, Yashtimadhu in Sanskrit; Family: Fabaceae) is a popular Indian medicinal plant mentioned as a Medhya Rasayana in Ayurvedic literatures and Nighantus. The important chemical constituent of Yashtimadhu is glycyrrhizin (about 2-9%), Glycyrrhetinic acid (glycyrrhetic) (0.5-0.9%). Isoflavonoids, chalcones, triterpenoids, coumarins, sterols, amino acids, amines, lignans, gums and volatile oils are other active constituents. These are found to be responsible for its various activities like antiulcer activity, wound healing activity, eye problems, cognitive function enhancing activity, anti-inflammatory, antioxidant activity, anti-tussive activity etc. Recent researches have also shown its positive effect as a memory enhancer, neuroprotectant, and attenuating neuroinflammation. In Ayurveda, Medhya rasayana comprises a major category of nootropic herbs that are indicated for all mental disorders. Yashtimadhu is one of Medhya drugs mentioned to enhance mental abilities, concentration, cognitive function and intelligence. The objective of this paper is to review the literature regarding its traditional uses, its impact on the Doshas, and the scientific evidence supporting its therapeutic properties
Significance of Vedhan Karma in Restricted and Painful Shoulder Joint Diagnosed as Vatarakta
Get PDFVatarakta is a disease of Avarana pathology caused by vitiated Rakta and Vata. The Vata gets vitiated by its own causes and its movement gets restricted by vitiated Rakta which leads to Vatarakta. In this disease, Vata and Rakta get vitiated by distinct etiological factors. One of the major causes of Rakta and Vata Dushti is trauma as told by Acharya Charaka in Jwar chikitsa. Severe pain is the major symptom of Vatarakta that gets relieved instantly by Raktmokshan as advised by Acharya Charak. Vedhan Karma was selected for Raktamokshan.
Vedhan Karma (piercing) is one of the eight surgical procedures (Ashtavidha Shashtra Karma) explained by Acharya Sushruta. It is very simple and cost-effective. The points of Vedhan are specific according to diseases.
After proper history taking and diagnosis, if Vedhankarma is done in the appropriate place we get instant results. It is safe, time-saving, and cost-effective. Hence a study was carried out using Vedhankarma in a case of painful, restricted movements of the left shoulder joint which was diagnosed as Vatarakta. For Vedhan, Suchee Shastra (26 no. needle) was used. The patient got instant relief from pain and improvement in restricted movement
Antimicrobial effect of Uthamadi Choorna during Ksharasutra Therapy in Bhagandara
Get PDFIn the modern era, ano rectal diseases are increasing day by day due to the changes in life style especially the food habits. Fistula in ano is one among them. It is a chronic illness which is, though not fatal but quite discomforting and troublesome to the patient and often puts a deep impact on the quality of life of a patient. Fistula in ano is a track lined by granulation tissue which connects peri anal skin superficially to anal canal, ano rectum or rectum deeply. The main clinical symptoms consist of pain, swelling and pus discharge. Due to higher recurrence rate and postoperative complication, fistula-in-ano is a headache in current surgical practice. Bhagandara which is described in Ayurveda classics can be correlated with Fistula in ano. Ksharasuthra therapy is a parasurgical procedure in Ayurveda which is found more effective in the management of fistula in ano. Even after Ksharasuthra application, pus discharge from fistulous tract delays the healing and makes the post operative period more difficult. So there is a need a of some adjuvant drug which can manage these problems in a better way and promote healing process by reducing the microbial load.Uthamadi Choorna is mentioned in Bhagandara prathishedha adhyayam in Ashtamga hrdaya and it contains Guggulu, Thriphala, Khadira and Asana which are having various chemical constituents that showed antimicrobial activity in pharmacological studies. The objective of the present study is to evaluate the antimicrobial effect of Uthamadi choorna during Ksharasuthra therapy in Bhagandara
A Review on Pharmacological and Therapeutic Aspect of Shirishadi Agada w.s.r. Vishachikitsa
Get PDFIn Agadtantra many Jangam (animal poison) and Sthawar visha (plant poisoning) are described and in treatment of Visha many Agada are described. Agad means drug or formulation of drug which act against poisons or neutralize the poisoning effects. Keet visha (insect bite) is one of the common poisoning in Jangam visha. In Ayurvedic Samhitas many Agada formulations are described in treatment of Keet visha. Shirishadi Agada is mentioned in treatment of Keet visha (insect bite), Sarp (snake bite), Luta (spider), Mushak (rat poison) and Vruschik visha (scorpion bite) in Ashtang hridayam in Uttarsthana. Shirishadi Agad is herbal formulation contains Shirish, Pippali and Arka. This review is for collective information about therapeutic and pharmacological action of Shirishadi Agada
Bhramari Pranayama - A Unique Voice Culturing Technique
Get PDFA good voice is the basic need of humans. For professional voice users, voice governs their livelihood and social attraction. A good singing voice is attained by the regular vocal exercises and vocal training. Singing involves the skills like respiration, phonation, resonance and articulation. Bhramari Pranayama (BP) involves both humming and respiration. Humming is the resultant of the activity vocal structures which may have effect on the quality of the voice. Aim: To evaluate the effect of Bhramari Pranayama (BP) on voice quality
Settings and Design: The study is an open clinical trial involving 30 healthy prospective singers fulfilling the inclusion and exclusion criteria, consenting for the study, who were enrolled through a survey in music schools in the region of Belagavi, Karnataka. Methods and Material: The voice of the 30 healthy prospective singers was recorded using PRAAT software with standard vocal tasks on day 0 of the study. Participants practiced 21 cycles of Bhramari Pranayama in the morning for 30 days. On Day 30, after the practice the voice was re-recorded with same vocal tasks and standard operative procedures being maintained. The recorded voice samples were saved and were subjected for voice analysis using softwares PRAAT, Vaghmi, CSL at AIISH, Mysuru. Statistical analysis used: Statistical analysis was done using SPSS 21 and Paired ‘t’ test was applied to derive the results. Statistical Significance was set up at p<0.05. Results: Bhramari pranayama showed highly significant results in the root mean square values of the Singing power ratio - SPR (p<0.01) and singing power difference (p<0.01). Significant results in the lowest value of the singing amplitude (p<0.05), singing amplitude range (p<0.01) and mean formant frequency of second formant of vowel /u/(p<0.05). Conclusion: Bhramari Pranayama improved the resonance characteristics of the voice and there by improved the quality of singing voice in prospective singers
A Conceptual Recapture of Stanya Kshaya and Role of Stanya-Janan Mahakashaya in its Management
Get PDFBreast milk is the prime source of nourishment and immunity of the baby. Stanya Kshaya, which appears to be a fairly simple ailment but is really problematic for children\u27s health, is one of the problems of present era. Lactation insufficiency is 30–40% prevalent in Asian and tropical nations like India. In Ayurveda certain herbs are specifically indicated for increasing breast milk and Acharya Charaka has described Stanya-janana Mahakashaya for it. Few explorations have been conducted regarding above, but no one has covered all aspects comprehensively thus this paper aim to collect and comprehensive review information available regarding concept of Stanya, its Kshaya and role of Stanya-janana Mahakashaya in its management. Methodology: This review is in a narrative format and done from literature and publications relevant to Stanya Kshaya and role of Stanya-janana Mahakashaya. Results: Stanya has been described in detail along with opinion of various Acharyas, Stanya sampata and the reasons for Stanyakshya mentioned then finally role of Stanya-janana Mahakashaya of Acharya Charaka which includes 10 herbs as- Veerana, Shali, Shasthik, Ekshuvalika, Darbha, Kusha, Kaasha, Gundra, Ithkata, Katruna. Drugs in this Kashaya help in increasing quantity of milk. Discussion: Stanya-janana Mahakashaya has active principles which increase quantity of milk, so can be used in Stanya Kshaya and leads to healthy Stanya
An Integrated Approach in Management of Pemphigus Vulgaris
Get PDFPemphigus refers to a group of autoantibody-mediated intra-epidermal blistering diseases characterized by loss of cohesion between epidermal cells (a process termed acantholysis). Applying pressure to the skin of these patients may elicit the separation of the epidermis which is known as Nikolsky’s sign. Pemphigus vulgaris can be compared with Agnivisarpa based on similar manifestation. The mainstay of treatment is systemic glucocorticoids in allopathy science. The current mortality is around 5% with glucocorticoids treatment. Case History: This case report is of 40 years old male patient who presented with blisters formation on whole over body, perspiration, itching and burning since last 6 months. He was treated in indoor department with Snehana Cikitsa mainly along with oral glucocorticoids for 25 days. The dose of oral glucocorticoids was tapered with improvement in patient’s condition. Result: At the time discharge, patient was prescribed 10mg prednisolone and oral Ayurvedic medicines. After 25 days of treatment patient had more than 90% relief and glucorticoids was stopped. On the 2nd follow of treatment patient was kept only on Ayurvedic medicines. During first two follow-ups, patient had significant relief