International Journal of Ayurveda and Pharma Research
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    2276 research outputs found

    The Ancient Art of Discussion: Insights from Charaka Samhita

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    Charaka Samhita is an ancient Indian medical treatise that has stood the test of time. It covers a vast range of topics from fundamental principles of Ayurveda to the diagnosis, treatment and prevention of diseases. Its Wisdom has inspired generations of scholars and seekers of knowledge, shaping the evolution of Indian thought and culture. In order to attain scientific knowledge, three different means of knowledge (Trividha jnanopaya) are mentioned in Charaka Samhita. It includes Adhyayana (learning), Adhyapana (teaching) and Tadvidya-Sambhasha (discussions and debates). Among them, Tadvidhyasambhasha plays an important role in shaping the current form of Charaka Samhita making it accurate by rectifying the mistakes. This article is intended for analyzing various instances of Tadvidya-Sambhasha and their outcomes in Charaka Samhita

    Association of Deha Prakṛti (Body Constitution) with Expression of Selected Inflammatory Markers in Patients with Chronic Kidney Disease (CKD) - Western Province, Sri Lanka

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    Deha prakṛti is a fundamental concept in Āyurveda, offers a promising approach to prevent and manage Chronic Kidney Disease (CKD) through an integrated perspective. While Deha prakṛti is widely recognized for its applications in predicting disease susceptibility, facilitating early detection, guiding treatment plan and influencing dietary and behavioral patterns, there is a notable gap in scientific evidence supporting its associations with various aspects of chronic disorders such as CKD. One such aspect is the immunological impairment in CKD patients, which is a significant concern that needs to be addressed immediately and no scientifically proven studies found in relation to the above in previous literature. In order to address this research gap, present study investigated the relationship between Deha prakṛti and specific inflammatory markers- namely Erythrocyte Sedimentation Rate (ESR), C- Reactive Protein (CRP), Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-α) in CKD patients, Western Province, Sri Lanka. An assessment of the association between Deha prakṛti and the expression of selected inflammatory markers in CKD patients would provide insights to successfully manage the disease by developing targeted treatment modalities focusing on inflammatory markers. The study involved 113 diagnosed CKD patients and their Deha prakṛti type was assessed using ĀyuSoft software. ESR and CRP levels were determined according to the Westergren method and CRP latex slide agglutination method respectively, while IL-6 and TNF-α levels were quantitatively measured using Enzyme Linked Immunosorbent Assay (ELISA) based on the sandwich principle. It was observed that the types of Deha prakṛti in CKD patients are significantly associated with the levels of ESR and IL- 6 indicating that the levels of ESR and IL - 6 inflammatory markers depend on the types of Deha prakṛti in CKD patients. However, it was also noticed that the types of Deha prakṛti were not significantly associated with the levels of CRP and TNF-α. This will lead the Āyurveda physicians to plan and develop specific treatment regimens with accurate drug dosage and dietary - behavioral patterns targeting the above inflammatory markers related to the Dehaprakṛti types of the CKD patients. Since it was also observed that CKD patients with Pitta and Vāta pradhāna prakṛti types are more susceptible to elevated levels of inflammatory markers, it is advisable to implement precautions during the early stages of the disease based on the specific type of Deha prakṛti in order to prevent the progression of the disease to End stage Renal Disease (ESRD)

    Ayurvedic Management of Shwitra (Vitiligo)

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    In Ayurveda, skin diseases are classified under Kushta Roga with Shwitra being one of its notable conditions. Shwitra is characterized by whitish patches on the skin, primarily resulting from the involvement of Sapta Dravyas i.e., Vata, Pitta, Kapha, Rasa, Rakta, Mamsa, and Meda. Shwitra is often correlated with vitiligo, a hypopigmentation disorder impacting about 1% of the global population. While Shwitra is not harmful in a physical sense, it can significantly affect a child’s social and mental well-being. Methodology- This case report presents a 13-year-old female patient came to SBLD Panchakarma OPD with complaint of white patches on her face and both upper and lower limbs, accompanied by mild itching but no burning sensation since one year. The initial treatment involved Shamana chikitsa followed by Shodhana Chikitsa for a period of three months, with regular follow-ups to assess changes in the size, no. and colour of the patches. This article discusses the Ayurvedic management of Shwitra, highlighting treatment efficacy. Result and Discussion- The patient exhibited notable improvement following Virechana and subsequent Shamana Aushadis. The treatment protocol effectively facilitated the re-pigmentation of the de-pigmented patches. No. of patches are reduced after treatment. This case underscores the potential of Ayurvedic treatments for Shwitra, reaffirming their efficacy as described in classical texts. Such outcomes could be fundamental in managing future cases of similar skin conditions. Conclusion- The rising incidence of vitiligo is linked to lifestyle factors, making it essential to address its causes through Ayurveda. Shwitra Chikitsa offers treatments that improve pigmentation and mental well-being. Using Shodhana and Shamana therapies, practitioners can target the root causes, reduce patches, and restore normal skin pigmentation while preventing recurrence

    Pharmaceutical Processing and Standardization of Modified Dosage Form of Jeevaneeyagana Kashaya as Spray Dried Powder Capsules

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    Jeevaneeyagana Kashaya is an Ayurvedic formulation that can be used for its preventive and therapeutic properties. However, its liquid dosage form has a limited shelf life and is difficult to administer. The present study works on standardizing and evaluating the Jeevaneeyagana Kashaya (JGK) extract capsules prepared using spray dryer technology, which consist of Withania somnifera, Asparagus racemosus, Pueraria tuberosa, Vigna trilobata, Teramnus labialis, Leptadaenia reticulata, and Glycyrrhiza glabra. The spray-dried extract was evaluated for phytochemical characters. Moreover, physical property analysis, such as bulk density, tapped density, compressibility index, and angle of repose for the formulated JGK extract capsules, was done. The capsules were evaluated for their organoleptic characters. Microbial load, heavy metal analysis, and disintegration time were also determined. The JGK extract capsule formulation complied with the assessed qualities. JGK extract capsule formulation complied with the assessed qualities. The JGK extract capsules can be used as a modified dosage form with increased shelf life and easy administration. The results of this study can be utilized as a reference standard for quality assurance of JGK capsules

    An Applied Study of Indriya Sthana w.s.r. to its Importance in Pariksha

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    Acharya Charak by "Pareekshyakaarino Hi Kushala Bhavanti” emphasizes the importance of examinations in all aspects of life and equates examination with knowledge. Examination is not possible without knowledge and neither is knowledge possible without examination. Our Acharyas from the very beginning have renovated Ayurveda obtained from Indra in the Rishi Sabhas by re-examination of the miserable condition of the diseased, examination of Ayurveda and appropriate Acharya with the eye of knowledge. The interest of Ayurveda mystics towards the examination is evident from the description provided. The knowledge of Samhitas includes various examinations related to health, disease, patients, diet, drugs, and age. These examinations cover pre-natal, gestational, and newborn assessments along with the examination of the age which is divided into two parts. One is a test of the entire age and the other is the evaluation of the remaining age for both a healthy person and patient. Its general examination can be done by Prakriti and Vikriti and in the special examination separate special expressions called Parikshya Bhavas have been examined. Acharyas have also described a method of examining the affected person\u27s senses, Chaya and Prabha to determine the extent to which they are unable to function properly. Aim & Objective: Study the parameters and processes of the examination described in detail in the Indriya Sthana and use it in health and medical science. Method: An in-depth study & analysis of Indriya Lakshanas from Brihatrayi along with their commentaries was done as a departmental study project. Conclusion: Examining the expressions mentioned in the context of Arishta Pariksha benefits in health, disease and death knowledge

    A Pharmaceutico-Analytical Study of Shirishadi Sharir Daurgandhyahara Yoga (SSD)

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    The importance of beauty and personality is increasing now a day as it is a competitive era. The urge of need of using perfumery and cosmetic was nurtured when person started using them. Need of beautification was correlated with attraction. The Indian tradition of perfumery and cosmetic is very old. Sweating is a normal physiological process; sweat is 99% water with some salt (NaCl), vitamin C, anti-bodies, traces of metabolic wastes and lactic acid composition. It’s a natural process to cool the body temperature. Thermal and emotional factors promote sweating. The moist environment created by Hyperhidrosis condition, creates an ideal conditions for an overgrowth of bacteria. Hyperhidrosis condition, bacteria break down certain proteins in the sweat into acids, so it is not the bacteria that stink. It is the by-product of the bacteria breaking down the protein. As we are living in the industrial era, where the problem of global warming a matter of great concern and is increasing radically, as a result of increasing temperature. People are suffering from excessive sweating and some people also posses bad odor with sweating. This situation will bring a huge psychological and social burden, because it will interferes with daily activities. Many people do not seek medical help because they do not know that their condition requires medical intervention. Due to excessive sweating it can cause various infections. Many people use antiperspirants products to control sweating and body odor. Some chemical antiperspirants are effective; however, the side effects like irritations, discoloration allergy, are also obvious

    Autophagy from Siddhars Perspective in Preventing Non-Communicable Diseases- A Review

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    Siddha system of medicine is one of the ancient medicines in the AYUSH system of medicines. It described the prevention and cure of disease through the ways of "Naal Ozhukkam" (daily regimen) and "Kaala Ozhukkam” (seasonal regimen). Fasting (Pattini) is one of these practices of Naal Ozhukkam. In 2016, a Japanese man named Mr. Yoshinori Ohsumi got his Noble Prize for finding the mechanism behind autophagy. Fasting is the most efficient method of activating autophagy. This review showed fasting in our Siddha literature and autophagy from Siddhars perspective in preventing non-communicable diseases. In our Siddha literature, it says that the uses of fasting are to rest our digestive organs, remove toxins and waste products from our bodies, and refresh our body cells. Autophagy is the body’s way of eliminating damaged cells in order to regenerate newer, healthier cells. Recent research has indicated roles for autophagy in an increasing number of pathologies, from bacterial and viral infections to cancer, and more recently in neurodegenerative and other age-related diseases. But during their period, Siddhars treat fever and some other diseases by fasting. By this method, they prevent non-communicable diseases. As a result, we must lead the Siddhars\u27 ideas by performing Naal ozhukkam and Kaala Ozhukkam to prevent non-communicable diseases

    Ayurvedic Management of Diabetes Mellitus (DM) and Diabetic Neuropathy: A Case Study

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    Diabetes is a burning problem of modern world and is associated with multiple complications. All oral hyoglycemic drugs and insulin used in modern medicine only help to lower blood sugar of body. The biological medicines are only available treatments which have limited effect and carrying many serious adverse effects. Purpose: The conventional medicine has its own limitation in this disease condition, it only help to lower blood sugar level of body and in a long run it has shown its side effects. They neither able to correct the pathology nor helpful to protect vital organs of the body and to prevent further complications. Ayurvedic treatment approaches are helpful in this disease. With the changing demand and awareness among these days, the role of Ayurveda is an emerging reality. Brief case history: A 49-year-old, married, Hindu male patient visited PD Patel Ayurvedic Hospital on 9th November 2021. He had been diagnosed with type 2 diabetes above 11 years and received medication for this. He was taking Tab. Metformine since last 11 years. He had chief complains of Madhuryamasyata, Karapadadaha, Pipasadhikya, Mootraadhikya since last 11 years, and other associated complains were Kshudha Vriddhi, Atichinta, and Nidravriddhi since last 4 months. He had gradually increased body weight in last year 2 years. He had been admitted and treated with Virechna karma and Basti chikitsa and oral Ayurvedic medicines for one month. After one month of treatment, he is continuing oral medicines only and he regularly comes for following up in OPD. Now on the second follow up patient had much improvement in above symptoms. His blood sugar level and weight were also reduced significantly. Result: He got an excellent result with complete relief from all symptoms as well as marked reduction in objective criteria (lab investigation) within 1 month

    Socio-Economic Importance and Potential of Wild Ayurvedic Medicinal Plants of the Western Himalayas, India

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    India\u27s Ayurvedic medicine system is becoming popular worldwide because these medicines are based on natural herbal products and have no side effects on health; somewhat, it improves and strengthens the body\u27s immunity. Today people’s awareness is increasing about health, the side effects of allopathy medicines on health, and their inclination and faith toward Ayurvedic treatments are railing with time. Ayurvedic medicine system is based on traditional herbal knowledge, identification of herbs in natural habitats, and formulations. The present study involves the survey and analysis of local healers of Shivalik hill in the Western Himalayas to discover the most used herbs and their economic potential from national and international market perspectives. Therefore, a survey and analysis were conducted in randomly selected 37 villages of six development blocks. The survey interviewed 195 local healers and people based on the scientifically designed questionnaire. During the 2019-2022, the thirty-one wild medicinal plant species were identified with, highlighting ten highly valued plants. These plants have high demand from local healers, vendors, or the pharma industry. Further analysis of the importance and value of each part of the plant shows this: leaves (15%), flowers (13%), roots (21%), seeds (27%), oil (2%), wood (4%), juice (11%), tuber (4%) and whole plant (4%). Study shows that local healers can. This study also emphasizes the cultivation of these herbal plants on a large scale and can potentially raise the financial status of local people and healers. The study highlights the potential of these herbal plants found in the study area to enhance rural livelihood and community resilience and calls for the integration of medicinal plants in conservation and development strategies

    A Critical Review on the Impact of Ayurvedic Dietetics (Pathya Apathya) in the Management of Dyslipidemia

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    Dyslipidemia is defined as abnormal amount of lipids in the blood. It is a metabolic disorder, manifested as increased plasma levels of total cholesterol, triglyceride or a decrease in high density lipoprotein. Dyslipidemia is the main disposing factor for the atherosclerosis, and the atherosclerosis is the main pathogenesis factor for cardiovascular disease. In Ayurvedic view, dyslipidemia can be considered similar to aggravated Dusta Meda Dhatu in the body which is caused due to hypofunction of Medo-Dhatwagni leading to Medovaha Srotodusti Vikara. Nidanparivarjana is the main treatment principle of Ayurveda. For dyslipidemia, diet which is Laghu, Ruksha, Kaphamedohara and Srotoshodhana property should be followed. While, Guru, Snigdha, Kaphamedokara and Abhishyandhi food should be avoided. According to Bhaisjya Ratnawali, Pathya for Hridroga are Dadima, Shunthi, Yavani, Patol etc while Apathya are Ksheer Vikruti, Dadhi, Guru Bhojan etc. Using healthy diet rich in complex carbohydrates, vegetables, and fruits seasoned with adequate quantity of spices with minimum amount of oils and fats are ideal for management and prevention of dyslipidemia. So this research article, will explain the properties of Pathya and Apathya their mode of action in prevention and management of dyslipidemia with the help of previous research work done on related Pathya Apathya food article

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