International Journal of Ayurveda and Pharma Research
Not a member yet
2276 research outputs found
Sort by
Sigrusireeshadi Yoga in Mandalivisha Chikitsa
Full text linkAgadatantra is one of the eight branches of Ayurveda that deals with toxicology. It primarily focuses on the study, prevention, diagnosis, and treatment of various toxic conditions affecting humans. Kerala has a rich and distinct tradition of Visha chikitsa renowned for its specialized therapies and effective management of venomous bites, food poisoning and environmental toxins. Many Malayalam texts that offer practical insights into toxicology, antidote formulations and indigenous treatment methods. Prayogasamuchaya is one among them which contain numerous formulations that are highly effective in managing various types of poisoning, venomous bites, and toxic conditions. Sigrusireeshadi yoga is explained in Triteeya paricheda ‘Mandali visha chikitsa’ of Prayogasamuchaya. It is indicated for external application in Mandali vishaja sopha. Swelling is the predominant symptom of viper bite, that requires emergency management. This Yoga contains 5 ingredients, including Sigru, Sireesha, Punarnava, Aswagandha and Sundi. This article aims to discuss the possible mechanism of action of Sigrusireeshadi yoga by analyzing its pharmacological properties. And the probable mode of use of this yoga in other Vishaja sopha
Efficacy of Virechana Karma in Gambheer Vatarakta wsr to Psoriatic Arthritis
Full text linkGambheer Vatarakta, a severe manifestation of Vatarakta, a condition where there is an imbalance of the Vata and Rakta doshas. Gambheer Vatarakta is characterized by Syavthu, Stabdhata, Arti, Shyava-tamra Twaka, Daha, Toda, Sphurana, Paka in joints, resembling the symptoms observed in psoriatic arthritis. The term Gambheer translates to severe or profound reflecting the intensity of the condition. Aim: The study seeks to evaluate the impact of Virechana Karma in Gambheer Vatarakta with special reference to psoriatic arthritis, symptoms including pain, swelling, and joint function, as well as its influence on the overall inflammatory and Dosha balance. Methods: A detailed case study was conducted on a 26-year-old female patient diagnosed with Gambheer Vatarakta. The patient underwent with a procedure of Virechana Karma, following a preparatory phase of Snehana (oleation) and Swedana (sudation). Clinical assessments were performed before and after the treatment regimen, including detailed symptom evaluations and laboratory tests to monitor changes in inflammatory markers and Dosha imbalances. Results: The Virechana Karma resulted in significant reduction in joint pain, swelling, and skin lesions. The patient experienced improved joint mobility and overall functional capacity. Laboratory tests showed a notable decrease and more balanced Dosha levels. The patient reported decreased severity of psoriatic symptoms, indicating an improvement in both the arthritic and psoriatic components of the condition. Conclusion: This case study demonstrates that Virechana Karma can be an effective treatment for managing Gambheer Vatarakta in context of psoriatic arthritis. The therapeutic purgation led to significant relief and improved functional outcomes. The study supports integration of Virechana Karma in treatment protocols for complex cases involving chronic inflammatory arthritis and suggests further research to confirm its broader efficacy and potential benefits
Incompatible Foods and Neurodevelopmental Disorders in Children: A Review of the Evidence
Full text linkNeurodevelopmental disorders such as Attention Deficit Hyperactive Disorder (ADHD), autism and anxiety are becoming more common in India, posing a significant economic and social burden on the country. Despite extensive research the exact causes of ADHD and autism remain unclear. Both conditions are multifactorial involving genetic, environmental and biological factors. Poor diet being a significant contributing factor for the increasing prevalence of neurodevelopmental disorders. Objective: Investigate the relationship between diet and neurodevelopmental disorders like ADHD and autism, and explore Ayurvedic principles in understanding this relationship. Data source extensive research on neurodevelopmental disorders, Ayurvedic texts, and modern scientific studies on diet\u27s impact on brain development and function. Review methods comprehensive review of existing research on neurodevelopmental disorders, Ayurvedic principles, and diet\u27s impact on brain health, considering modern food consumption patterns. Result: Poor diet is a significant contributing factor to neurodevelopmental disorders. Consuming preserved foods, high sugar, and unhealthy fats leads to inflammation, oxidative stress, and disruption of the gut-brain axis. Conclusion: Ayurvedic principles provide valuable insights into the relationship between diet and neurodevelopmental disorders. Identifying new food incompatibilities relevant to modern food consumption patterns may help develop dietary interventions to prevent or manage these disorders
Ethnomedicinal Overview of Sesamum Indicum (Tila) as Described in the Brihatrayees
Full text linkSesamum indicum (Tila) is a revered oilseed plant extensively used in the Ayurvedic system of medicine since ancient times. Its reference dates back to the Vedic era, where it was commonly used in sacrificial rituals, religious offerings, and as a dietary and therapeutic substance. Classical Ayurvedic literature, as well as other ancient Indian texts, have documented the medicinal applications of Tila for a variety of human health conditions. The present review aims to compile the therapeutic uses of this significant medicinal plant as described in the Brihatrayee-the three foundational texts of Ayurveda: Caraka Samhita, Sushruta Samhita, and Ashtanga Hridaya. The study reveals that various parts of Sesamum indicum, especially its oil (Tila tailam), seeds, and paste, are frequently mentioned for their health-promoting properties. These include applications in skin care, wound healing, strengthening of bones and teeth, enhancing vitality, and managing disorders of Vata and Pitta doshas. The review underscores a substantial potential for further pharmacological and clinical research to validate and integrate these classical uses into contemporary Ayurvedic practice
Comparative Clinical Efficacy of Oil Prepared with Stem Bark and Fruit of Shirisha in the Management of Darunaka (Dandruff) - A Randomised, Single Blind Clinical Study
Full text linkDarunaka, a Kshudra Roga classified under Kapalagata Roga in Ayurveda, is a common scalp disorder characterized by Kandu (itching), Kesacyuti (falling of hair), Ruksata (dryness), Tvaksputana (scaling/cracking of skin). It primarily arises due to vitiation of Vata and Kapha Doshas. Despite being non-fatal, it significantly impacts an individual\u27s quality of life and aesthetics. This study aimed to comparative clinical efficacy of oil prepared with stem bark and fruit of Shirisha in the management of Darunaka (dandruff), assessing its role in Dosha Samana (pacification), symptom relief, and overall patient wellness. A clinical study was conducted involving patients diagnosed with cardinal symptoms of Darunaka. The trial formulation was administered as external application for 30 days. Classical Ayurvedic diagnostic criteria, as well as modern clinical parameters, were employed for assessment. Pre- and post-treatment observations were documented, focusing on signs such as Kandu, Kesacyuti, Tvak ruksata, and Tvaksputana. The results indicated a significant reduction in classical signs and symptoms of Darunaka. Improvements were noted in scalp health, reduction in itching. The therapy was well-tolerated by all participants, with no adverse effects reported. The study reinforces the efficacy of classical Ayurvedic approaches and suggests further large-scale research to validate these findings and integrate traditional treatments into contemporary scalp care
A Comprehensive Analysis of Anger from the Perspective of Ancient Indian Literatures, Ayurveda and Western Psychology
Full text linkDifferent Indian literatures have discussed the genesis of anger along with its different negative impact with approaches to overcome it, among which Ramayana, Mahabharata and Bhagavad Gita are principal ones. Apart from them various other texts like Patanjali’s Yoga Sutras, Manusmriti, Chanakya Niti Darpana etc. also have discussed the various aspect of anger. Likewise principal Ayurvedic texts like Charaka Samhita and Sushruta Samhita also addressed this topic and discussed thoroughly about its genesis, character, assessment and its role in causation of diseases. Likewise, in recent times many modern psychologists also have investigated anger as a global social problem and threw light on its physiological and cognitive aspects. Discussions: Patanjali’s Yoga Sutra viewed anger as one of the Chitta Vrittis as well as among Pancha Klesha. Patanjali advised to overcome anger by habituating the mind into contrary ideas. Manusmriti viewed anger as a negative emotion which has lots of repulsion in human’s social and personal life. Likewise, other texts on morality and ethics like Chanakya Niti Darpana, Panchatantram, Hitopadesha etc. have similarly analysed anger and its negative impact. Primarily Charaka Samhita and Sushruta Samhita also described anger as product of vitiation of Pitta Dosha as well as Raja - Tama Dosha. In addition, Charaka Samhita also discussed the method of assessment of anger, its anthropological genesis in Kali Yuga, its importance as forbidden object in various compromised conditions. They have discovered new facts like role of amygdala in provocation of anger. Based on all these findings, the present authors have chalked out some fundamental approaches of anger management from the perspective of ancient Vedic tradition, Ayurveda as well as modern psychology. Conclusions: The present study is a novel approach in discussing anger with all its psychopathology, impact on personal and social life as well as its management in a comprehensive manner showing the perspectives of age-old Indian literatures, various texts of Ayurveda as well as modern psychology
A Single Arm Clinical Study to Evaluate the Efficacy of Katankateriyadi Kwatha in the Management of Madhumeha (Diabetes Mellitus Type-2)
Full text linkMadhumeha is known to Indian system of medicine since time immemorial. Almost all texts available, however old contain one or another very lucid hint of Prameha. This along with all of its causes, etiopathognesis, symptomatology, treatment and complications are mentioned in all Ayurvedic texts written centuries ago. It’s inclusion in eight major diseases (Astamahagada) indicates the significance and gravity attributed to it. Here 40 cases of newly diagnosed type 2 diabetes mellitus in a patient who underwent 3 follow up i.e., 30th, 60th, 90th of Katankateriyadi kwatha delivered in 3 months is reported. The patient’s fasting blood glucose and post plasma blood glucose levels, as well as HbA1C level were decreased after treatment. Further-more, no adverse effects were observed. The results of this clinical study are encouraging and provide evidence supporting the effectiveness of Katankateriyadi Kwatha in reducing Madhumha (Diabetes Mellitus Type-2) in a patient
Literature review of Vasa in various Ayurvedic treatise
Full text linkAdhatoda vasica Nees., also known as Malabar nut or Vasa, has long been utilized in traditional medicine for its potent respiratory therapeutic properties. This plant has been used for 2000 years to treat respiratory problems. The leaves of this plant give a stimulant effect on the respiratory system. In Ayurveda medicinal system it is considered a potent herb to cure diseases like cough, symptoms of cold, asthma, bronchitis. Vasa is said to have Tikta and Katu in Rasa and Sheet in Veerya it has Katu Vipaka and is said to have Kapha-Pittahara property. Vasa was reviewed in various text like Veda, Samhita, Kosha Grantha. Vasa was found to be as the main ingredient of many formulations in the treatment of Raktpitta, Kaphaj Vikar, Vataj Vikar, and other respiratory diseases. Vasa Swarasa was found in various formulations used as Bhawana Dravya, also various Paryaya, Guna, Karma and different opinions of Acharyas in various Samhitas were observed
Effect of Yava Syamaka Peya and Suryanamaskara in Overweight Adults
Full text linkOverweight refers to abnormal or excessive fat accumulation that presents a risk to health. Overweight is currently widespread in both developed and developing countries, affecting both children and adults. A higher prevalence is observed among individuals of high socioeconomic status, particularly in urban areas. Modern lifestyles and poor dietary habits are the primary factors contributing to the development of overweight. If not managed promptly, overweight can progress to obesity, leading to a host of pathological complications. The management of overweight should focus on promoting appropriate dietary choices and boosting energy expenditure through physical activity. Yava Syamaka Peya mentioned in Bhavaprakasha Nighantu was adopted as a dietary intervention. Along with this diet, Suryanamaskara was made into the daily routine of participants for a period of 3 months. The intervention, consisting of 300ml of Yava Syamaka peya along with the daily practice of 12 rounds of Suryanamaskara, was conducted in 31 subjects. The results were analysed using the paired t-test and repeated measures ANOVA test. The study found a considerable reduction in body weight, with an average loss of 6.65 kg over 3 months. Participants experienced an average decrease of 2.645 kg/m² in BMI and a reduction of 0.035 in the waist-hip ratio. Additionally, FBS decreased by 14.71 mg/dl, and total cholesterol levels dropped by an average of 23.42 mg/dl. These results were statistically significant. From this, it is concluded that the intake of Yava Syamaka peya along with the practice of Suryanamaskara for 3 months is effective in reducing overweight
Utility of Agnikarma in Day to-Day Practice
Full text linkAgnikarma is an important para surgical procedure used in Ayurveda widely accepted for pain management since ages. The therapy includes the controlled transfer of varied degree of heat to the affected part with wide therapeutic intentions. Acharya Sushruta, the pioneer of Agnikarma stresses on multifaceted utility of Agnikarma and mentioned that it could be a potential alternative when management using medicine surgery or Kshara fails. He claims non-recurrence of benign pathologies when treated by Agnikarma. Though one can be fascinated by these claims, deeper understanding of the procedure is much essential to achieve the success. As therapy requires fire which could be hazardous and end up in burns. Thus, it is very essential to analyze Agnikarma vidhi in depth and understand logic behind selection of ideal patient, choosing the right device and conducting the procedure without any un toward event with proper precautions. Also knowing the idea behind contraindications allows us to prevent complications in current era. So here is an attempt to understand the rationality behind the various steps included in Agnikarma