International Journal of Ayurveda and Pharma Research
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Pharmaceutical Standardization and Analytical Assessment of Shunthyadi Tailam: A Comprehensive Study
Full text linkShunthyadi tailam, a classical Ayurvedic formulation as Nasya therapy mentioned in Ashtang hrudaya for therapeutic use in Bhrushakshava. Bhrushakshava can be compared to the acute phase of allergic rhinitis. This study focuses on its pharmaceutical preparation and analytical standardization, adhering to the guidelines of the Ayurvedic Pharmacopoeia of India. The formulation was subjected to organoleptic and physico-chemical evaluations to establish benchmark standards. Key parameters such as acid value, saponification value, iodine value, specific gravity and refractive index were analyzed. These findings provide a scientific foundation for future research and ensure the quality and consistency of Shunthyadi tailam in therapeutic applications
Development and Characterisation of Anti-Septic Cream Containing Turmeric, Aloe Vera Gel and Jatyadi Oil
Full text linkThe need of herbal medicines is increasing rapidly due to their fewer side effects. Herbal drugs constitute a major part in all the traditional system of medicine. Hence an attempt has been made to formulate and evaluate cream for its antiseptic activity against Propionic Bacteria. In this context, the study has been conducted to formulate polyherbal cream using turmeric, aloe vera extract and Jatyadi oil, all the extracts are obtained by using various extraction techniques such Maceration, Steam distillation and Soxhlet apparatus. Preliminary phytochemical screening was carried out for all the herbal extracts the final formulation was evaluated for different evaluation parameters. The formulation was evaluated for antiseptic activity against Propionic bacteria by MIC method
Comparison of Colony Forming Units (CFU) Between Prepared and Market Samples of Selected Aristas in the Kerala Market
Full text linkThe study compares the Colony Forming Units (CFU) of prepared and market samples of three Aristas: Abhayarista, Balarista, and Jeerakarista, which are fermented Ayurvedic medicines. Aristas naturally generate alcohol through fermentation facilitated by yeast found in Woodfordia fruticosa Kurz, with Jaggery serving as the sugar source. The fermentation process spans 30-45 days, during which complete sugar utilization ensures optimal results. Incomplete fermentation, however, can cause post-fermentation issues and acidity development. The microbial fermentation process is characterized by distinct growth phases: a lag phase for acclimatization, a log phase for exponential growth, a deceleration phase due to reduced energy reserves, and a stationary phase where microbial activity stagnates but viability is maintained. The presence of residual sugar can trigger renewed fermentation cycles, leading to post-fermentation challenges. For this analysis, three samples of prepared Aristas and five corresponding market samples from the Kerala market were tested. CFU was assessed using the Mueller-Hinton agar method, and statistical evaluation employed a one-sample t-test. The results revealed a significant difference in CFU levels in two of the market samples (p < 0.01), while the remaining samples showed no significant variation (p>0.05). This study highlights the variability in CFU between prepared and market samples, emphasizing the importance of consistent fermentation processes in ensuring the quality of Ayurvedic fermented medicines
Role of Rasayana Prophylaxis in Degenerative Disorders: A Comprehensive Review
Full text linkDegenerative disorders are characterized by progressive tissue and organ deterioration and pose significant challenges to health and quality of life, especially in ageing populations. The degenerative disorders, including osteoarthritis, Alzheimer’s disease, cardiovascular diseases, and osteoporosis, are characterized by the progressive deterioration in the structure and function of tissues and organs due to oxidative stress, biological ageing, and chronic inflammation. Through its Rasayana therapy, which is the core concept and prophylactic measures, Ayurveda offers comprehensive and holistic strategies for managing and preventing these conditions. Derived from the Sanskrit words Rasa and Ayana, Rasayana emphasizes enhancing overall health by nourishing tissues, enhancing immunity, balancing the body’s Doshas and delaying the ageing process. Through its antioxidant, anti-inflammatory and adaptogenic properties, which mitigate oxidative damage, regulate immune responses and improve cellular repair mechanisms. Prophylactic use of Rasayana not only prevents the onset of degenerative disorders but also delays their progression by improving cellular adaptability, slowing age-related decline and enhancing metabolism. This article explores the application of Rasayana and prophylaxis in managing and preventing degenerative disorders, emphasizing herbal, dietary and lifestyle interventions. It also highlights key Rasayana formulations, such as Ashwagandha (Withania somnifera), Amalaki (Emblica officinalis), Guduchi (Tinospora cordifolia), Brahmi (Bacopa monnieri), etc., and their roles in reducing inflammation, enhancing adaptability against age-related decline, and supporting tissue regeneration. Incorporating Rasayana and prophylaxis into the contemporary healthcare system offers a sustainable and effective pathway to address the rising burden of degenerative disorders
Effectiveness of an Ayurvedic Formulation (Allergy Rakshak Avaleha) Alone and in Combination (with Allergy Rakshak Ghee) for Managing Allergic Rhinitis: An Open-label Randomized Controlled Study
Full text linkAllergic rhinitis is a common health concern worldwide, and Ayurveda offers potential alternatives to manage its symptoms and underlying causes. Objectives: This study evaluated the efficacy and safety of Allergy Rakshak Avaleha alone and in combination with Allergy Rakshak Ghee. Materials and Methods: An open-label, randomized controlled study was conducted on participants aged 18 to 65 with allergic rhinitis. Participants were randomly assigned to three groups: Group I received Allergy Rakshak Avaleha (½ spoon twice daily), Group II received Allergy Rakshak Avaleha (½ spoon twice daily) and Allergy Rakshak Ghee (2 drops in each nostril twice daily), and Group III received standard therapy with levocetirizine (5mg) and montelukast (10mg) once daily for 28 days. The primary outcomes were the changes in Total Nasal Symptom Score (TNSS), IgE levels, and eosinophil count at the end of the treatment (EoT), and at the 1-month follow-up. The secondary outcomes included changes in quality of life (QoL) and adverse events. Results: A total of 240 participants (80 per group) were enrolled in the study. All groups demonstrated a significant reduction (p<0.05) in TNSS, with Group II showing the greatest reduction in TNSS compared to Group III. Serum IgE levels did not show significant changes across any groups. No adverse events were reported in any of the groups. Conclusion: Allergy Rakshak Avaleha, both alone and in combination with Allergy Rakshak Ghee, was found to be safe and effective in managing allergic rhinitis. However, a randomized controlled trial with a larger sample size is recommended
A Breakthrough Approach to Managing Chronic Plaque Psoriasis in Ayurveda by Sequential Purification Therapies
Full text linkPsoriasis vulgaris, the most prevalent form of psoriasis, commonly manifests in early adulthood and is marked by a chronic, relapsing course. In India, its prevalence ranges from 0.44% to 2.8%. This immune-mediated dermatological condition severely affects the quality of life by imposing physical, emotional, and social burdens. A 31-year-old male presented with dry, itchy, erythematous, scaly, and well-demarcated plaques symmetrically distributed over the scalp, trunk, and limbs. Based on Ayurvedic clinical evaluation, the condition was diagnosed as Ekakustha (plaque psoriasis). An integrative approach using classical Ayurvedic Shodhana (purification) therapies was employed, beginning with Virechana Karma (therapeutic purgation) followed by Basti Karma (medicated enema), in accordance with traditional management protocols for chronic skin disorders. Over the course of treatment and follow-up, the patient showed significant clinical improvement, including reduction in lesion size and severity, normalization of skin tone, and relief from pruritus and discomfort. This case highlights the importance of repeated systemic cleansing in managing chronic and relapsing conditions like psoriasis. The therapeutic response observed suggests that Panchakarma therapies may offer a promising complementary strategy in the long-term, individualized management of plaque psoriasis. Further research and well-designed clinical studies are warranted to substantiate these findings and integrate traditional interventions into evidence-based dermatological practice
A Comprehensive Analysis of Avarana in Ayurveda: Theoretical Foundations, Clinical Significance, and Therapeutic Perspectives
Full text linkIn Ayurvedic literature, diseases associated with Vatha are considered particularly serious, with Avarana being identified as a crucial pathological process in their progression. In the current social scenario, where sedentary lifestyles prevail, a majority of Vatha disorders can be linked to Avarana, though the underlying mechanisms of this association remain inadequately explored. Avarana refers to the disturbed movement of Vatha, due to the obstruction or by other Doshas, Dhatus (tissues), Malas (waste products), etc. Detailed analyses of the pathogenetics of Avarana suggest that diverse pathological pathways contribute to the development of Avarana across various conditions, with clinical manifestations often dominated by the encroaching factor rather than the entrapped Vatha, albeit with certain exceptions. Diagnosis is achieved through meticulous symptom observation and iterative treatment trials. The general therapeutic approach for Avarana involves pacifying Vatha, cleansing the bodily channels, and addressing the encroaching dosha. If left untreated, Avarana can precipitate the progression to serious disease states. Redefining Samprapti through the perspective of Avarana paves the way for crafting more refined and effective treatment strategies, ultimately nurturing better patient well-being
An Open Labelled Randomized Controlled Clinical Study to Evaluate the Effect of Vardhamana Balamoola Rasayana in Gridhrasi w.s.r to Sciatica Syndrome
Full text linkGridhrasi, a Nanathmaja vata vyadi, manifests in two distinct forms: Vataja and Vata-Kaphaja. Despite the availability of conventional treatments, patients often experience only temporary relief. Rasayana Chikitsa, a traditional approach, offers a promising long-term solution. This study aims to evaluate the effectiveness of Rasayana Chikitsa in managing symptoms of Gridhrasi and improving patient outcomes. Objectives: To evaluate the therapeutic effect of Vardhamana Balamoola Rasayana in Gridhrasi. Methodology: A randomized controlled clinical study was conducted on 30 patients, aged 18-70 years, who attended the outpatient department (OPD) of the institute with low back pain radiating to lower limbs. These patients met the diagnostic criteria and participated in the study. The participants were divided into two groups: Group A, which received Vardhamana Lashuna Rasayana for 16 days, and Group B, which received Vardhamana Balamoola Rasayana for 30 days. The treatment protocol involved mild purgation followed by incrementally increasing doses. Efficacy was assessed using both subjective criteria (pain, stiffness, functional ability) and objective criteria (Straight Leg Raise (SLR) test) at baseline, during treatment, and post-treatment. Statistical analysis was performed using paired t-tests, Wilcoxon\u27s signed-rank tests, unpaired t-tests, and Mann-Whitney U tests to evaluate the treatment outcomes. Results: Vardhamana Balamoola Rasayana showed superior efficacy, with 20% achieving maximum relief. It also had higher mild relief rates (46.66% vs. 26.66%) and lesser minimum relief rates (0% vs. 40%). Conclusion: Vardhamana Balamoola Rasayana demonstrated superior efficacy in pain management, functional ability, and neurological deficit reduction, making it a more effective therapeutic option for Gridhrasi symptom relief
Ayurvedic Management of Alopecia Areata
Full text linkAlopecia areata is an autoimmune disease condition characterized by patchy, non-scarring hair loss due to immune-mediated damage to hair follicles. It commonly affects the scalp, beard, and moustache areas, with exclamatory hairs often visible at the lesion margins. The condition usually manifests between the second and fourth decades of life and is influenced by genetic, environmental, and psychological factors. In Ayurveda, alopecia areata is correlated with Indralupta explained under Kapalagata Roga by Acharya Vagbhata and Kshudra Roga by Acharya Sushruta. Indraluptha is occurs due to the vitiation of Vata and Pitta doshas in the hair root (Romakoopa), leading to hair fall, followed by Kapha and Rakta doshas obstructing regrowth. Prachana, a type of Raktamokshana (bloodletting), is considered the first line of treatment. In this case study, a 20-year-old male with Alopecia areata was successfully treated with Ayurvedic Shodhana (purificatory) and Shamana (pacifying) therapy. Complete hair regrowth and symptom relief without recurrence were the outcomes of the treatment. This result emphasizes how Ayurvedic treatments can provide a comprehensive and long-lasting strategy for treating alopecia areata by addressing its underlying causes and reestablishing systemic equilibrium
A Pharmacological and Therapeutic Plant Review of Bhallataka (Semecarpus Anacardium) in Classical and Modern Medicine
Full text linkBhallataka (Semecarpus anacardium Linn.), commonly known as the marking nut tree, is a widely utilized medicinal plant in Ayurveda, recognized for its diverse pharmacological activities. Classical Ayurvedic texts such as Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya, and various Nighantus extensively document its properties, formulations, and therapeutic indications. It is classified under Upavisha (semi-poisonous drugs), requiring meticulous purification (Shodhana) before internal use. Various parts of the plant-particularly the seed, kernel (Majja), fruit, and oil-exhibit actions such as Deepana, Pachana, Krimighna, Shukrala, Rasayana, and Kaphavatahara. These properties make Bhallataka valuable in treating conditions like Kushtha (skin disorders), Arsha (piles), Grahani (IBS), Gulma (abdominal masses), Pandu (anaemia), and Vatarakta (gout). Modern pharmacological research has corroborated many classical claims, demonstrating its anti-inflammatory, immunomodulatory, antimicrobial, antioxidant, and anticancer effects. Phytochemical investigations reveal bioactive constituents like bhilawanol, semecarpol, anacardol, and biflavonoids responsible for its therapeutic efficacy. Despite its efficacy, improper handling may cause severe toxic reactions; hence, traditional antidotes and dietary guidelines (Pathya-Apathya) are crucial during administration. This review compiles comprehensive information from classical and contemporary sources to present a holistic understanding of Bhallataka-from its botanical description, purification techniques, therapeutic actions, and formulations to modern evidence-based validations highlighting its integrative significance in traditional and modern medicine