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Bibliometric mapping of anemia in geriatric surgery
No full textObjective: In this study, scientific literature on anemia in geriatric surgical patients was reviewed using bibliometric analysis. Trends, scientific collaborations, and research gaps were identified. Method: On March 1, 2025, 640 articles were included in the analysis after searching the Web of Science database using MeSH terms such as geriatrics, elderly, surgery, anaemia anemia. Bibliometric evaluation was performed using the Biblioshiny interface. Publication years, authors, journals, keywords, countries, and collaborations were analyzed. Results: A total of 3376 authors took part in 640 articles published between 1984 and 2025. The average number of citations per article was 9.54. BMJ Case Reports and International Journal of Surgery Case Reports had the highest number of publications. According to Keywords Plus analysis, the most common terms were management, surgery, mortality and diagnosis. Discussion: This study examined the literature on anemia in elderly surgical patients using a bibliometric method and analyzed the research trends, collaborations, and knowledge structure in this field using the Web of Science database. This study highlighted the negative effects of anemia on surgical outcomes, identified gaps in the literature, and provided recommendations for future research. These findings provide a comprehensive assessment of the field in accordance with the interdisciplinary and complex nature of the subject. Conclusion: Key dynamics and gaps in the field were identified. In particular, significant research gaps were identified, including a lack of international collaboration, inadequate multidisciplinary approaches, and limited publications in some thematic areas (e.g., frailty and blood transfusion protocols). These findings can guide future, more comprehensive, and collaborative studies targeting these gaps
Inhibition Effects of Some Phenolic Anthraquinone Derivatives on Lactoperoxidase Activity: A Detailed in Vitro and in Silico investigation
Get PDFThe basic nutrient of all living beings in the developmental age is milk. Milk contains many things necessary for ideal nutrition. One of the enzymes found in bovine milk is lactoperoxidase (LPO; EC 1.11.1.7). The LPO system functions as a natural defense system, especially in newborn babies. Despite the many benefits of milk, contamination of breast milk with environmental toxins is common. Over time, people accumulate a lifetime load of chemicals from drugs to environmental pollutants, and these can be passed on to the baby during breastfeeding. Anthraquinones are colorful compounds that can be produced both naturally and synthetically. These compounds are widely used in industry and medicine due to their biological activities and colorful structures. In this study, in vitro enzyme inhibition study, molecular docking and molecular dynamics (MD) simulation parameters were examined to investigate the inhibitory potential of anthraquinone derivatives, which are widely used as coloring agents, against the lactoperoxidase enzyme. The inhibitors showed competitive inhibition with Ki values between 0.4964 +/- 0.042-2.0907 +/- 0.1044 mu M. 1,2-Dihydroxy-anthraquinone was predicted to have the highest affinity on the LPO receptor, with estimated free binding energies of -7.11 kcal/mol. The stability of both ligand and protein, as shown by the low RMSD and RMSF values, shows that 1,2-dihydroxy-anthraquinone (2) maintains strong and stable interactions throughout the MD simulation, further supporting the high binding affinity and potential biological activity of the compound. We hope that this study will guide the development of drugs targeting the LPO enzyme with anthraquinone derivatives.Scientific and Technological Research Council of Turkiye (TUEBITAK)Open access funding provided by the Scientific and Technological Research Council of Turkiye (TUEBITAK)
Anticancer and probiotic activities of Lacticaseibacillus paracasei isolated from traditionally fermented pickles
Get PDFBackgroundProbiotics are living organisms and play a pivotal role in the natural treatment of gastrointestinal disorders including diarrhea, constipation, lactose intolerance and some bowel cancers. Beneficial effects are mostly attributed to postbiotic metabolites produced by bacteria, and the unique biological characteristics may vary depending on their species and source. The present study focused on identifying unique Lacticaseibacillus paracasei strains with unique probiotic and anticancer effects originating from fermented pickles.ResultsBacterial strains isolated from naturally fermented pickles were identified by 16S rRNA sequence analysis. Their probiotic properties were determined in simulated gastrointestinal environments created by pancreatin and pepsin. In addition, their adhesion capacities on L-929, HT-29 and Caco-2 cell lines were tested and then the cytotoxic effects of postbiotic metabolites and bacterial extracts obtained from bacterial isolates on cell lines were tested to determine their anticancer activities. In the overall results, isolates were found to be acceptable probiotics and to have anticancer activity.ConclusionIn addition to the acceptable activities of all strains, by elucidating their interaction mechanisms and evaluating their probiotic, functional and antiproliferative effects under in vivo conditions, especially LP001 and LP002 could be true sources of probiotics with anticancer effects in food and healthcare fields. (c) 2025 Society of Chemical Industry.Mus Alparslan University Scientific Research Projects Unit [BAP-20-SHMYO-4901-01]This study was funded by Mus Alparslan University Scientific Research Projects Unit with project support no. BAP-20-SHMYO-4901-01
Determination of ecological literacy levels and perceptions of social studies teacher candidates
Get PDFBu araştırmada sosyal bilgiler öğretmen adaylarının ekolojik okuryazarlık algılarının, düzeylerinin ve bu düzeye etki eden değişkenlerin belirlenmesi amaçlanmıştır. Araştırma kapsamındaki nicel ve nitel veriler katılımcılardan eş zamanlı olarak elde edildiği için araştırma karma yöntemlerden zenginleştirilmiş desen ile tasarlanmıştır. Araştırmanın örneklemi, uygun örnekleme metodu ile belirlenmiştir. Bu bağlamda araştırmada kullanılan nicel ve nitel veriler Türkiye'deki üç devlet üniversitesindeki sosyal bilgiler öğretmenliği ana bilim dalında öğrenim gören tüm sınıf düzeyindeki araştırmaya gönüllü olarak katılmak isteyen öğrencilerden elde edilmiştir. Araştırmada 207 katılımcıdan elde edilen nicel veriler ve 101 katılımcıdan elde edilen nitel veriler yer almaktadır. Nicel veriler araştırmacı tarafından geliştirilen demografik bilgi formu ile Koçoğlu, Gürbüz, Tösten, Demir ve Tekdal (2023) tarafından geliştirilen "Ekolojik Okuryazarlık Ölçeği" aracılığıyla nitel veriler ise yine araştırmacı tarafından geliştirilen metafor formu aracılığıyla elde edilmiştir. Veriler elde edildikten sonra analizlerin gerçekleştirilebilmesi için Google Form sistemindeki veriler SPSS ve Excel programlarına aktarılmıştır. Yapılan analizler sonucunda sosyal bilgiler öğretmen adaylarının ekolojik okuryazarlık ölçeğinin tamamından ve alt boyutlarından aldıkları puanların yüksek düzeye yakın olduğu belirlenmiştir. Hipotez testleri sonucunda ise kadın öğretmen adaylarının erkek öğretmen adaylarına göre, çevre eğitimi alan öğretmen adaylarının da çevre eğitimi almayan öğretmen adaylarına göre ekolojik okuryazarlıklarının anlamlı olarak daha yüksek olduğu belirlenmiştir. Sınıf düzeyi bakımından ele alınan hipotez testine göre ise üst sınıflarda öğrenim gören öğretmen adaylarının ekolojik okur yazarlık düzeylerinin alt sınıflarda öğrenim gören öğretmen adaylarına göre daha yüksek olduğu tespit edilmiştir. Diğer bir hipotez testine göre ise yaşamının çoğunu büyükşehirde geçiren öğretmen adaylarının ekolojik okuryazarlık düzeylerinin şehir, ilçe ve köyde geçiren öğretmen adaylarına göre daha yüksek olduğu sonucuna ulaşılmıştır. Metafor formundan elde edilen nitel verilere yapılan içerik analizi bağlamında sosyal bilgiler öğretmen adaylarından 83 adet metafor elde dilmiştir. Bu metaforlar arasından en sık rastlanan metaforlar "bilinçli insan/tüketici olma", "çark", "merhamet", "nefes alma", "öğretmen", "sağlık", "saygı", "sevgi", "sorumluluk" ve "toprak"tır. Literatür incelendiğinde araştırmadan elde edilen bulguların paralelinde sonuçlar gösteren birçok araştırmaya rastlanılmıştır. Elde edilen bu sonuçlar doğrultusunda ekolojik okuryazarlık kavramının dünya genelinde önem taşıyan bir kavram olduğu göz önüne alındığında yalnızca sosyal bilgiler öğretmenlerinin değil diğer öğretmen adayları ile de ekolojik okuryazarlık kavramı çerçevesinde araştırmaların yapılması önerilebilir. Ayrıca bu çalışmada yer alan değişkenlerden farklı olarak başka değişken setleri ve ölçeklerle de ekolojik okuryazarlık kavramı ve bu kavramla ilişkili diğer kavramlara yönelik çalışmaların yapılması gerektiği söylenebilir.The aim of this study is to determine social studies pre-service teachers' perceptions and levels of ecological literacy, as well as the variables affecting these levels. Since both quantitative and qualitative data were obtained from participants simultaneously, the study was designed using the embedded design, one of the mixed methods. The sample of the study was determined through convenience sampling. In this context, the quantitative and qualitative data used in the research were collected from students at all grade levels who voluntarily participated in the study and were enrolled in the Social Studies Education departments of three public universities in Turkey. The study includes quantitative data from 207 participants and qualitative data from 101 participants. The quantitative data were collected using a demographic information form developed by the researcher and the "Ecological Literacy Scale" developed by Koçoğlu, Gürbüz, Tösten, Demir, and Tekdal (2023), while the qualitative data were obtained through a metaphor form also developed by the researcher. After the required approvals were obtained, the questions in the data collection tools were transferred to Google Forms, and the links were shared with advisors in the Social Studies Education departments of the participating universities. After data collection, the data from Google Forms were transferred to SPSS and Excel for analysis. The analyses revealed that the pre-service social studies teachers scored close to a high level on the overall ecological literacy scale and its sub-dimensions. The results of hypothesis tests showed that female pre-service teachers had significantly higher ecological literacy levels compared to their male counterparts, and those who had received environmental education had significantly higher ecological literacy levels compared to those who had not. Another hypothesis test showed that pre-service teachers in upper-grade levels had higher levels of ecological literacy than those in lower-grade levels. Furthermore, it was found that those who spent most of their lives in metropolitan cities had higher ecological literacy levels than those who lived in cities, districts, or villages. Content analysis of the qualitative data obtained from the metaphor form revealed 83 different metaphors provided by the pre-service teachers. The most frequently mentioned metaphors included "being a conscious person/consumer," "gear," "compassion," "breathing," "teacher," "health," "respect," "love," "responsibility," and "soil." A review of the literature revealed many studies with results parallel to those of this research. In light of these findings, considering that ecological literacy is a globally significant concept, it can be suggested that research on ecological literacy should not be limited to social studies teachers but also include other teacher candidates. Furthermore, it can be recommended that future studies examine ecological literacy and related concepts using different sets of variables and measurement tools
Stajyer Filminin Örgütsel Davranış Açısından İncelenmesi: Örgüt İklimi, Liderlik, Motivasyon ve Çatışma Üzerine Bir Okuma
Get PDFBu çalışmada, Nancy Meyers’ın 2015 yapımı Stajyer (The Intern) filmi örgütsel davranış perspektifinden incelenmektedir. Çalışmada, filmde yer alan liderlik, motivasyon, örgüt iklimi ve çatışma unsurları ele alınmış; bu unsurların iş dünyasında bireyler ve organizasyonlar üzerindeki etkileri değerlendirilmiştir. Film, farklı kuşaklardan bireylerin bir arada çalıştığı modern bir startup şirketinin dinamiklerini etkileyici bir biçimde yansıtarak, örgütsel davranışın çeşitli boyutlarının anlaşılmasına olanak sağlamaktadır. Çalışmanın temel amacı, Stajyer filmi üzerinden örgütsel davranış unsurlarını betimlemek ve bu unsurların örgütsel başarı ile çalışan memnuniyeti üzerindeki etkilerini ortaya koymaktır. Araştırmada, betimsel analiz yöntemi kullanılmış; filmdeki olaylar ve karakterler örgütsel davranış teorileri çerçevesinde detaylı bir biçimde incelenmiştir. Betimsel analiz, görsel materyallerin sistematik bir şekilde değerlendirilmesini sağlayarak, film ile literatürdeki teorik çerçeve arasındaki ilişkiyi somutlaştırmada etkili olmuştur. Araştırma bulguları, filmdeki liderlik, motivasyon, örgüt iklimi ve çatışma yönetimi unsurlarının örgütsel başarı üzerindeki belirleyici rollerini ortaya koymaktadır. Film, bu unsurların etkili yönetiminin iş yerinde sürdürülebilir bir başarıyı nasıl desteklediğini vurgulamaktadır. Örgüt iklimi, liderlik ve motivasyon gibi unsurların doğru yönetilmesi hem bireylerin hem de organizasyonların performans ve memnuniyet düzeyini artırmaktadır. Çatışma yönetimi ise, açık iletişim ve empati yoluyla çözüm odaklı bir yaklaşıma dönüştürülebilmektedir. Sonuç olarak, Stajyer filmi, örgütsel davranış kavramlarının anlaşılmasına katkı sağlayan önemli bir akademik kaynak niteliği taşımakta olup, modern iş dünyasının dinamiklerini analiz etmede etkili bir araç olarak değerlendirilmektedir
A Technical-Tactical Analysis of Medal Matches in Wrestling: Results from the 2024 European Senior Championships
Get PDFBackground and Objective: Match analysis plays a vital role in forming the scientific foundation of training and guiding strategic decision-making in wrestling. By objectively evaluating athletes' technical and tactical performances, coaches and athletes can optimize preparation and in-match strategies. This study aimed to analyze the technical and tactical characteristics of medal matches in Greco-Roman (GR), Freestyle (FS), and Women's Wrestling (WW) at the 2024 European Wrestling Championships. Methods: A total of 54 elite-level matches (18 from each style), held in Bucharest between 12 and 18 February, 2024, were retrospectively analyzed. Three expert observers evaluated the matches using video footage from the United World Wrestling (UWW) archive. Descriptive statistics were performed using SPSS 25.0. Results: Across 301 recorded actions, 2-point techniques (52.16%) and 1-point techniques (43.85%) were dominant; only 3.99% were 4-point actions. GR primarily utilized body lock and gut wrench; FS favored single-leg attacks and leg lace. In WW, the scores were obtained from techniques applied in the par terre position with a high frequency (60.8%). Most victories in all styles occurred by points rather than technical superiority or falls. Conclusion: The findings reveal a strategic preference for low-risk, controlled techniques in high-level matches. These insights can inform evidence-based training and match preparation for future championships
Improving the Accuracy of Groundwater Level Forecasting by Coupling Ensemble Machine Learning Model and Coronavirus Herd Immunity Optimizer
Get PDFGroundwater levels are under severe pressure globally due to over-extraction, pollution, and climate change necessitating continuous monitoring for sustainable aquifer management. This study introduces a novel ensemble machine learning (En) model that integrates shallow and deep machine learning (ML) models, optimized through the coronavirus herd immunity optimizer (CHIO), for accurate groundwater level forecasting. This En model was applied to the Ergene River Basin, Turkiye, a region facing severe groundwater depletion and contamination due to intensive agricultural and industrial activities. Groundwater level data spanning 1966 to 2023 on a weekly basis from four wells were used, split into 70% for training and 30% for testing under short- and long-term scenarios. Using the partial autocorrelation function and gamma test the best lag numbers were determined for input data, reflecting aquifer heterogeneity. Score analysis, supported by statistical metrics such as the coefficient of determination (R-2) and root mean square error (RMSE), was employed alongside visual aids to assess the developed En model performance. Results demonstrated that deep ML models outperformed shallow ML models achieving R-2 similar to 0.99 and RMSE similar to 0.5 m. The developed En model outperformed all individual ML models, with score values exceeding 200, and its predictions closely aligned with measured water levels during both testing phases. The findings underscored the developed En model's contribution to achieving sustainable development goals (SDGs) by enhancing water-use efficiency and addressing environmental, economic, and social sustainability challenges. The proposed approach offers a reliable and adaptable solution for groundwater level forecasting, applicable to other aquifers worldwide.Science, Technology & Innovation Funding Authority (STDF)Egyptian Knowledge Bank (EKB)Faculty of Engineering, Mansoura University, Mansoura, EgyptOpen access funding provided by The Science, Technology & Innovation Funding Authority (STDF) in cooperation with The Egyptian Knowledge Bank (EKB).This research was supported by the Faculty of Engineering, Mansoura University, Mansoura, Egypt. Besides, open access funding is provided by The Science, Technology & Innovation Funding Authority (STDF) in cooperation with The Egyptian Knowledge Bank (EKB)
Investigation of researches on natural disaster: A meta-synthesis analysis
Get PDFBu tez çalışması 2013-2023 yılları arasında doğal afetler ile ilgili yapılmış nitel çalışmaların meta-sentez analizi yöntemi ile incelenmesini içermektedir. Çalışma Türkçe olarak yazılmış makale ve tezlerden oluşmaktadırThis thesis study includes the examination of qualitative studies on natural disasters conducted between 2013 and 2023 using the meta-synthesis analysis method. The study consists of articles and theses written in Turkish
Effects of eight-week TRX training on body composition, anaerobic power and some biomotor characteristics in young male volleyball players
Get PDFBu çalışmanın amacı, genç erkek voleybolcularda sekiz haftalık TRX antrenmanlarının vücut kompozisyonu, anaerobik güç ve bazı biyomotor özellikler üzerindeki etkilerini incelemektir. Araştırmaya, Muş Spor Lisesi voleybol takımında oynayan, 14-18 yaşları arasındaki 26 erkek voleybolcu gönüllü olarak katılmıştır. Sporcular randomize şekilde Deney (n=13) ve Kontrol (n=13) gruplarına ayrılmıştır. Kontrol grubundaki sporcular yalnızca rutin voleybol antrenmanlarına devam ederken, deney grubuna rutin antrenmanlara ek olarak TRX antrenman programı uygulanmıştır. Sekiz haftalık antrenman programının öncesinde ve sonrasında vücut kompozisyonu ölçümleri ile birlikte anaerobik güç, dikey sıçrama, el kavrama kuvveti, bacak kuvveti ve 10 metre sürat testleri uygulanmıştır. Veriler SPSS paket programı kullanılarak analiz edilmiştir. Verilerin normalliği Shapiro- Wilk testi ile değerlendirilmiş ve tüm değişkenlerin normal dağılıma sahip olduğu belirlenmiştir (p>0,05). Normal dağılım gösteren verilerin analizinde tekrarlı ölçümler için varyans analizi (ANOVA) kullanılmıştır. Çalışma bulgularına göre, sekiz haftalık TRX antrenmanları; 10 metre sürat koşusu, dikey sıçrama, bacak kuvveti ve zirve güç parametrelerinde istatistiksel olarak anlamlı gelişmeler sağlamıştır (p0,05). Sonuç olarak, TRX antrenmanlarının, genç erkek voleybolcularda patlayıcı kuvvet, sürat ve anaerobik güç gibi performansa yönelik parametreler üzerinde olumlu etkiler yarattığı söylenebilir.The aim of this study was to investigate the effects of an eight-week TRX training program on body composition, anaerobic power, and selected biomotor abilities in young male volleyball players. Twenty-six volunteers (aged 14–18) from the Muş Sports High School volleyball team participated in the research. The athletes were randomly assigned to an experimental group (n = 13) or a control group (n = 13). While the control group continued only their regular volleyball training, the experimental group completed a TRX program in addition to their routine sessions. Before and after the eight-week training period, assessments were conducted for body composition, anaerobic power, vertical jump, hand-grip strength, leg strength, and a 10-m sprint test. Data were analyzed using the SPSS software package. Normality was checked with the Shapiro–Wilk test, and all variables were found to be normally distributed (p > .05). Repeated-measures analysis of variance (ANOVA) was employed to analyze normally distributed data. The results showed statistically significant improvements in 10-m sprint performance, vertical jump height, leg strength, and peak power after the eight week TRX program (p .05). As a result, it can be stated that TRX training has positive effects on performance-related parameters such as explosive strength, speed, and anaerobic power in young male volleyball players
The effects of game-based virtual reality application on labor pain and childbirth satisfaction in primiparous pregnant women: A randomized controlled study
No full textWe conducted this randomized controlled experimental study to determine the effects of game-based virtual reality (VR) applications on labor pain and childbirth satisfaction in 120 primiparous pregnant women. The intervention group received game-based VR intervention combined with non-pharmacological methods for managing labor pain, while the control group received routine care. In comparison to the control group, the intervention group had significantly lower pain levels (p < 0.001) and significantly higher childbirth satisfaction levels (p < 0.001). According to our findings, the use of game-based VR was associated with reduced labor pain and increased childbirth satisfaction, suggesting its potential as an innovative approach to improving maternal health outcomes globally.Scientific Research Projects Unit of Idot;nonu University [TDK-2020-2165]This study was supported by the Scientific Research Projects Unit of & Idot;nonu University (Project No: TDK-2020-2165)