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SynCABEL: Synthetic Contextualized Augmentation for Biomedical Entity Linking
No full textInternational audienceWe present SynCABEL (Synthetic Contextualized Augmentation for Biomedical Entity Linking), a framework that addresses a central bottleneck in supervised biomedical entity linking (BEL): the scarcity of expert-annotated training data. SynCABEL leverages large language models to generate context-rich synthetic training examples for all candidate concepts in a target knowledge base, providing broad supervision without manual annotation. We demonstrate that SynCABEL, when combined with decoder-only models and guided inference establish new state-of-the-art results across three widely used multilingual benchmarks: MedMentions for English, QUAERO for French, and SPACCC for Spanish. Evaluating data efficiency, we show that SynCABEL reaches the performance of full human supervision using up to 60% less annotated data, substantially reducing reliance on labor-intensive and costly expert labeling. Finally, acknowledging that standard evaluation based on exact code matching often underestimates clinically valid predictions due to ontology redundancy, we introduce an LLM-as-a-judge protocol. This analysis reveals that SynCABEL significantly improves the rate of clinically valid predictions. Our synthetic datasets, models, and code are released to support reproducibility and future research
Apologie de la disco: Volume ! recherches sur les musiques populaires, vol. 23, no 1, 2026
No full textRichard Dyer, “In Defence of Disco”, Gay Left, vol. 8, 1979, en ligne : www.gayleft1970s.org/issues/issue08.as
Autonomie de l’employeur et incompatibilité des mandats syndicaux et sociaux, note sous Cass. soc., 19 nov. 2025, no 24-16.430
No full textInternational audienc
Geometric Structures in -enriched adjunctions
No full textA real matrix determines tropical row and column polytopes in tropical projective spaces and , with canonical polyhedral cell structures that are naturally dual.We reinterpret this picture via Isbell duality: viewing as an -enriched profunctor, we study the associated order-reversing Isbell adjunction and its fixed-point locus, the nucleus .After projectivization, carries two interacting geometries.On the metric side, -enrichment induces a canonical Hilbert projective--type (max-spread) metric on projective(co)presheaves, and we show that the projective Isbell maps identify the presheaf and copresheaf realizations of by mutually inverse isometries.On the polyhedral side, in the discrete real setting the Isbell inequalities cut out a canonical polyhedral decomposition of recovering the usual tropical cell structure.Our main new ingredient is a pointwise invariant of a nucleus point : the nonnegative gap matrix.Its zero pattern determines the cell containing , while its positive entries compute exact metric distances to theboundary strata where additional inequalities become tight (Events Theorem).This distance-to-wall principle refines cells into order chambers and supports a constructible tower of complete lattices obtained by thresholding
Nanoarchitectonics of Pro-Degradative Coating to Enhance Iron Corrosion Behavior and Biosafety for Bioresorbable Cardiovascular Stents
No full textInternational audienceControlling both the resorption rate and the formation of reactive oxygen species (ROS) of biodegradable iron (Fe) remains a central challenge for bioresorbable cardiovascular stents. Here, we introduce an innovative, nanoengineered surface coating strategy to simultaneously accelerate Fe corrosion and suppress ROS generation without altering the bulk Fe materials. Aryl-diazonium salt chemistry (4-cyanobenzene diazonium tetrafluoroborate, DCN) was used to creates robust polyaryl interphases that can immobilize gold nanoparticles (Au NPs) on Fe, establishing nanoscale microgalvanic and catalytic sites. Electrochemical analysis reveals that the coating increases the overall Fe corrosion rate while biasing cathodic oxygen reduction reaction towards the four-electron pathway, thereby reducing peroxide/OH• formation. This mechanism is supported by the remarkably reduced OH• content detected by terephthalateprobe assay. Corrosion metrics show a pronounced, controllable rate enhancement relative to bare Fe, and the post-corrosion exposure interfacial spectroscopy/microscopy verify the persistence of Au NPs, attributed to atomic Fe-FeO-Au interactions and anchoring by the DCN-derived polyaryl layer. Endothelial cells culture indicates favorable adhesion and viability, supporting cytocompatibility of the modified surface. This surface-chemistry-driven mechanism establishes a general interfacial principle for rate-and pathway-control of iron biodegradation, offering a concise route to safer, faster-resorbing Fe-based stents
Scarifier l’oreille : de la normalisation des troubles de l’audition: in Matthieu Saladin & Bastien Gallet (dir.), Spectres de l'audible, Paris, Philharmonie de Paris
No full textJonathan Sterne, “Audile Scarification”, in Diminished Faculties. A Political Phenomenology of Impairment, Durham, Duke University Press, 202
Linear Realisability and Implicative Algebras
No full textRealizability, introduced by Kleene, can be understood as a con-cretization of the Brouwer-Heyting-Kolmogorov (BHK) interpre-tation of proofs, providing a framework to interpret mathematicalstatements and proofs in terms of their constructive or computa-tional content. Over time, this concept has evolved through variousextensions, such as Kreisel’s modified realizability or Krivine’s clas-sical realizability. Parallel to these developments, Girard’s workon linear logic introduced another perspective, often seen as an-other concrete realization of the BHK interpretation. The resultingconstructions, encompassing models like geometry of interaction,ludics, and interaction graphs, were recently unified under the termlinear realizability models to stress the intuitive connection withintuitionnistic and classical realizability.The present work establishes for the first time a formal link be-tween linear realizability models and the realizability constructionsof Kleene and Krivine. Our approach leverages Miquel’s framework:just as linear logic can be viewed as a decomposition of intuitionisticand classical logic, we propose a linear decomposition of implicativealgebras and show that linear realisability models provide concreteexamples of such decompositions
Ancrage relationnel et écriture en ligne des personnages en fanfiction
No full textInternational audienc
Tensions in empowerment- or community-based HIV prevention interventions: lessons learned from ETOILE, a collaborative France–US self-study project
No full textInternational audienceIn most high-income countries, human immunodeficiency virus (HIV) has concentrated among minoritized, discriminated against, or otherwise marginalized communities, such as queer people, people who migrated, people who exchange sex and/or use drugs, poor people and people of color. Suboptimal prevention and treatment uptake has led to the implementation of community-based and/or participatory research integrating ‘empowerment’ approaches in an effort to reach marginalized groups in high-income countries. Here we present results of a cross-national examination of how national contexts influence implementation of empowerment-based HIV prevention research projects in the United States (US) and France. ETOILE was a qualitative, self-reflective study collaboration conducted between 2019 and 2022. Three study teams (two from the US and one from France) engaged in self-reflective focus groups and intervisitations where both HIV prevention scientists and community-based organization partners discussed the following topics: HIV and community-based research landscapes, the notion of empowerment in traditional research contexts, within-project tensions around hierarchies/power, positionality and racial representation, and economic resources. We applied a grounded analytic approach to identify key emergent themes. The ability to communicate around structural racism differed across study teams; the French team had greater difficulty managing within-project tensions, reflecting the national context and history of community-based research. Whether and how epidemiological data is broken down (or not) by ‘race,’ ethnicity, and social class shape both research and popular understandings of HIV epidemics. The roles of community-based organization members and Black researchers in accessing communities and vouching for research is particularly challenging. Representation of Black researchers on study teams can critically influence research project implementation. We found that national contexts matter. We identified recommendations for conducting community-based research based on empowerment and participatory approaches in disempowering contexts
FILTRATIONS OF THE PERVERSE SHEAF OF NEARBY CYCLES IN THE SEMI STABLE SITUATION by
No full textIn the strict semi stable reduction situation, we describe the various filtrations of the perverse sheaf of nearby cycles coming from the stratification of the special fiber and determine which extensions given by these filtrations, are split or not. Considering the similarity with the results with my paper at Duke Math. J., it could be a good introduction before reading loc. cit