Zonguldak Bülent Ecevit University Institutional Repository
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Investigation of the Post-Fire Behavior of Different End-Plated Beam–Column Connections
Heat affects the mechanical properties of steel and the bearing capacity of steel structures, with joints being a crucial factor in determining their behavior. Steel can regain its mechanical properties that are lost owing to heat if the temperature remains below 600 °C, allowing for the possibility of reusing steel after cooling. In such cases, it becomes essential to assess the damage caused by heat exposure to decide whether to demolish the structure or continue using it. However, continuing its usage requires anticipating the potential negative effects of heat. To achieve this, it is necessary to determine the behavior of steel joining tools experimentally or numerically after exposure to heat. This study aims to ascertain the post-fire behavior of various end-plated beam and column connections, providing a cost-effective alternative to expensive fire experiments. Three different end-plated combination models were heated to a specified temperature, and steel frames were constructed after the elements cooled. Six three-point bending tests were conducted, and the experimental data obtained were validated using finite element models. The results indicate that the temperature causes a reduction in the bearing capacity of the joint, and the length of the end plate has a significant effect on the connection behavior. The finite element model validated by experiments is expected to facilitate numerical studies with different characteristics.</jats:p
3 Boyutlu Yazıcı ile Üretilen Akrilik Rezinler ve Nanopartikül İlavesi
Sağlık alanındaki son gelişmelerin bir parçası olarak nanoteknoloji, atom ve moleküler seviyede malzemeler geliştirip üretmeyi amaçlamakta ve üstün özelliklere sahip biyomalzemeler sunmaktadır. Diş hekimliği uygulamalarında ve protez kaidelerinin üretiminde konvansiyonel olarak polimetilmetakrilat (PMMA) sıklıkla kullanılmakla birlikte, son yıllarda 3 boyutlu (3B) baskı teknolojisi ve rezinlerinin de kullanımı yaygınlaşmaktadır. Bu teknolojik ilerlemelerin, diş hekimliği alanında materyal biliminin gelişimine önemli ölçüde katkı sunacağı ve hastalara daha dayanıklı, estetik ve fonksiyonel restorasyon seçenekleri sunabileceği öngörülmektedir. Protetik diş hekimliğinde kullanılan akrilik bazlı materyaller ve 3B yazıcı rezinlere nanopartiküllerin ilavesi ile materyallerin mekanik ve fiziksel özelliklerinin iyileştirilmesi konusu son yıllarda literatürede sıklıkla araştırılmaktadır. Nanopartiküllerin, özellikle titanyum dioksit, gümüş ve zirkonyum gibi metal nanopartiküllerin mekanik avantajlar sağlayarak protetik diş hekimliğinde kullanılan materyallerin gelişimine katkıda bulunabileceği gözlenmektedir. Bu derleme çalışmasında, nanoteknolojinin ve 3B baskı teknolojisinin diş hekimliği uygulamalarında kullanımları ile birlikte, titanyum dioksit, gümüş, çinko oksit, silikon oksit ve zirkonyum dioksit gibi nanopartiküller ve bu nanopartiküllerin 3B yazıcıda üretilen akrilik rezinlere ilavesinin materyalin fiziksel ve mekanik özellliklerine olan etkisi anlatılmaktadır.</jats:p
The association between C-reactive protein/albumin ratio and aortic arch calcification in acute coronary syndrome patients
Purpose: We evaluated the association between the severity of aortic arch calcification (AAC) and C-reactive protein/albumin ratio (CAR) in acute coronary syndrome (ACS) patients. Materials and Methods: 288 patients who presented with ACS and underwent coronary angiography were enrolled analysis. CAR was calculated as serum CRP/albumin x 10. The AAC was separated into four groups (0 to 3): Grade 0-1 AAC was defined as the non-severe AAC group, and those with grade 2-3 AAC were defined as the severe AAC group. Results: CRP and CAR were significantly higher in the severe AAC group than in the non-severe AAC group. Multivariate analysis determined that CAR and age were positively associated in ACS patients as an independent predictor of severe AAC. CAR area under the curve (AUC) and CRP AUC demonstrated parallel curves compared to albumin levels, indicating higher statistical significance. The AUC for albumin was 0.349 (95% CI: 0.286-0.413). The AUC for CAR was 0.695, 95% CI 0.625 to 0.753, for CRP the AUC was 0.684 (95% CI: 0.620-0.748). After stratification into 2 groups according to the CAR cut-off value (1.664), the rate of severe AAC was importantly often in high CAR patients compared to in low CAR patients (56.7% vs 23.7%). Conclusion: CAR, an easily calculable, repeatable, and valid surrogate marker of inflammation, can be used reliably to indicate severe AAC in ACS patients.</jats:p
The Structure of Open and Distance English Language Teaching Models: A Follow Up Study 2018 – 2023
In recent years, the widespread adoption of Open and Distance Learning (ODL) has revolutionized education, especially English language teaching. ODL has democratized access to educational resources and enables interaction between students and instructors across geographical boundaries. Moreover, technology integration has emerged as a dominant theme, with a focus on web-based, computeraided, and mobile-learning systems. However, the study advocates for innovative approaches, such as mobile and game-based learning, aligning with contemporary trends. The adoption of various evaluation methods shows the recognition of individual differences and underscores the need for a comprehensive view of learner progress. This research employs a systematic approach to review literature and investigate the common structures of ODL models for teaching the English language, focusing on articles published between 2018 and 2023. This study categorizes studies based on five macro dimensions of ODL —management, communication, learning, technology, and evaluation—in order to identify common themes and patterns within the literature. In contrast to a previous study spanning 1990 to 2017, this investigation uncovers the evolving landscape of distance education, underscoring the need for continued research and improvement. This research emphasizes the lack of a comprehensive management model for EFL education delivered through ODL, and suggests the need for further investigation in this domain. Moreover, the findings emphasize the significance of leveraging diverse communication models to enhance learner engagement. A shift towards autonomous learning models is observed, demanding further investigation into strategies that support effective self-directed learning experiences. In conclusion, this comprehensive analysis provides a roadmap for advancing ODL models in English-language education. To enhance the quality and accessibility of English language instruction in ODL, educators and researchers can concentrate on addressing management gaps, optimizing communication strategies, promoting autonomous learning, exploring advanced technologies, and refining evaluation approaches. This research offers a rich repository of knowledge for educators, researchers, and academic institutions that wish to deepen their comprehension and practical application of ODL approaches in the domain of English language instruction</jats:p
G-20 ÜLKELERİNDE CO2 EMİSYONU, EKONOMİK BÜYÜME, KENTLEŞME VE YENİLENEBİLİR ENERJİ TÜKETİMİ İLİŞKİSİ
Sera gazı emisyonlarının küresel ısınma ve iklim değişikliği gibi insan sağlığı ve çevre açısından ciddi tehdit oluşturan olaylara sebebiyet vermesi ülkeleri, sera gazı emisyonlarının büyük bir bölümünü oluşturan CO2 emisyonlarının azaltmak için önlemler almaya yönlendirmiştir. Mevcut çalışmada; kişi başı CO2 emisyonu, kişi başı gayri safi yurtiçi hâsıla, kentleşme ve yenilenebilir enerji tüketimi arasındaki ilişkinin G-20 ülkeleri için 2020 verileri kullanılarak Robust Regresyon Analizi ile belirlenmesi amaçlanmıştır. Analizde CO2 emisyonu bağımlı değişken; kişi başına gayri safi yurtiçi hasıla, kentsel nüfus oranı ve yenilenebilir enerji tüketimini ise bağımsız değişken olarak kullanılmıştır. Robust regresyon analizi sonucuna göre Kanada ve Brezilya’nın aykırı gözlem olduğu tespit edilmiştir. Kişi başına gayri safi yurtiçi hasıla ile CO2 emisyonları arasındaki ilişki pozitif iken; yenilenebilir enerji tüketimi ve kentsel nüfus oranının ile CO2 emisyonları arasındaki ilişki negatif yönlü olarak tespit edilmiştir. Tüm bu bağımsız değişkenler %5 anlamlılık düzeyinde istatistiksel olarak anlamlı bulunmuştur</jats:p
The Effect of Inhaler Treatment with a Therapeutic Nebulizer Designed with 3D Printing Technology on Children’s Psychosocial Symptoms
Objective: This research was carried out with the aim of minimizing psychosocial symptoms such as fear, anxiety and crying by hospitalized children undergoing inhaler treatment with a nebulizer developed with three-dimensional printing technology, and to examine the effect of this method on parental satisfaction. Methods: The study is of experimental design. 44 children between the ages 2-7 receiving inhaler therapy with a nebulizer and their parents were recruited into the experimental and control groups. The researchers collected the data with “Scale for Identifying Psychosocial Symptoms in Hospitalized Children” and the “PedsQL Healthcare Satisfaction Scale.” Results: In the experimental group, 81.8 percent of the children being treated with a three-dimensional printing therapeutic device who had previously received treatment in the same way were not fearful, while 27.3 percent of those being treated with a standard type of nebulizer in the control group were unafraid (X2=24.246; p&lt;0.001). While those who were not crying at the time of their therapy made up 71.9% in the experimental group (X2=28,686; p&lt;0.001). The t-test performed to compare the pre- and posttests in the experimental group revealed a significant difference of p=0.002. Conclusions: It was concluded that inhaler therapy administered with a therapeutic nebulizer designed with three-dimensional printing technology reduced psychosocial symptoms and positively impacted parental satisfaction. This study highlights that was carried out with the aim of minimizing psychosocial symptoms by hospitalized children undergoing inhaler treatment with a nebulizer developed with three-dimensional printing technology.</jats:p
OCCUPATIONAL HEALTH AND SAFETY IN THE LOGISTICS SECTOR: AN EXAMINATION OF WORK ACCIDENTS IN TURKEY
This study analyzes the significant role of occupational health and safety (OHS) in the rapidly growing logistics sector. The high incidence of work-related accidents in Turkey’s logistics sector clearly highlights the extent of the risks faced by workers. The study provides a detailed examination of work accidents, occupational diseases, and fatality rates in the sector, based on the Social Security Institution (SSI) statistics from 2008 to 2023. The findings comprehensively reveal the work accidents and safety measures in the logistics sector. The research offers strategic recommendations for reducing these accidents and provides a methodological framework for developing policies to improve occupational safety in the sector.</jats:p
Rediscovering Harmankaya: A Critical Habitat for Bryophyte Biodiversity in Zonguldak, Türkiye
This study investigates the bryophyte biodiversity of Harmankaya Waterfalls Nature Park in Zonguldak, Türkiye, an area with critical biological significance for hornworts and other bryophyte species. Fieldwork conducted in 2023-2024 documented bryophyte diversity across three environmental zones based on substrate-water interaction levels. A total of 164 bryophyte taxa were identified, including 3 hornwort, 39 liverwort, and 122 moss taxa, with 32 new records for the Zonguldak bryoflora. Bryodiversity was assessed using the Shannon diversity index, revealing that Zone II, characterized by a mix of aquatic, semi-aquatic, and terrestrial taxa, exhibited the highest diversity. This study highlights the need for enhanced conservation strategies for Harmankaya due to increasing anthropogenic pressures from recreational activities, underscoring the importance of reevaluating its protected status.</jats:p
Fatalism tendency and health beliefs about medication use in older adults: A predictive correlational design
This study was performed to investigate fatalism tendency and health beliefs about medication use and to identify predisposing factors of these variables among older adults.A predictive correlational design was used. The study was completed with 500 older adults. A personal information form, the Fatalism Tendency Scale, and the Drug Use Health Beliefs Scale were used to collect data. Univariate and multiple linear regression analysis was performed for data analysis.Fatalism tendency was found to be high in older adults who used medications prescribed by the physician in different ways, used the medications more than the recommended amount, and used medications at random intervals. Older adults who used over-the-counter medications and discontinued the medications before the due date had lower health beliefs about conscious and prescription medication use.The study concluded that characteristics regarding medication use predicted both fatalism tendencies and medication use health beliefs. Health perception was found to be one of the predisposing factors of medication use health beliefs, whereas education level was another predictive factor of fatalism tendency
Discovery of a Therapeutic Agent for Glioblastoma Using a Systems Biology-Based Drug Repositioning Approach
Glioblastoma (GBM), a highly malignant tumour of the central nervous system, presents with a dire prognosis and low survival rates. The heterogeneous and recurrent nature of GBM renders current treatments relatively ineffective. In our study, we utilized an integrative systems biology approach to uncover the molecular mechanisms driving GBM progression and identify viable therapeutic drug targets for developing more effective GBM treatment strategies. Our integrative analysis revealed an elevated expression of CHST2 in GBM tumours, designating it as an unfavourable prognostic gene in GBM, as supported by data from two independent GBM cohorts. Further, we pinpointed WZ-4002 as a potential drug candidate to modulate CHST2 through computational drug repositioning. WZ-4002 directly targeted EGFR (ERBB1) and ERBB2, affecting their dimerization and influencing the activity of adjacent genes, including CHST2. We validated our findings by treating U-138 MG cells with WZ-4002, observing a decrease in CHST2 protein levels and a reduction in cell viability. In summary, our research suggests that the WZ-4002 drug candidate may effectively modulate CHST2 and adjacent genes, offering a promising avenue for developing efficient treatment strategies for GBM patients.</jats:p