Osaka Dental University Academic Repository / 大阪歯科大学学術リポジトリ
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Kinetic control of threading and dethreading in linked rotaxanes via hydrogen bonding.
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Effects of PEEK surface treatment using alumina blasting or concentrated sulfuric acid etching in combination with functional monomers on shear bond strength to adhesive cement after artificial aging.
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Hinokitiol exhibits potent anticancer effects in human oral squamous cell carcinoma by inducing apoptosis and inhibition of cell migration.
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末梢血から作製したConcentrated Growth Factorsが抜歯創治癒に与える影響
Get PDF大阪歯科大学Osaka Dental University博士（歯学）This study investigated the effects of Concentrated Growth Factors (CGF) on extraction wound healing using beagle dogs. CGF, derived from blood by excluding blood cells, contains fibrin and growth factors that promote hemostasis and cell proliferation, potentially accelerating wound healing. An experimental group with CGF implanted into extraction wounds was compared to a control group without implantation. Four weeks post-extraction, the control group exhibited inflammatory cells, capillaries, and irregular collagen fibers, while the experimental group showed increased new bone volume and fewer inflammatory cells. After 12 weeks, the control group displayed coarse bone surfaces, whereas the experimental group had smooth, dense bone surfaces with bone trabeculae. Additionally, tall osteoblasts and tartrate-resistant acid phosphatase-positive cells were more prevalent in the control group. These results suggest CGF accelerates the healing process, leading to earlier wound closure. This technology holds potential for improving orthodontic treatment outcomes.doctoral thesi
ムチンとL(-)-プロリンとを用いた人工的獲得被膜の形成
Get PDF大阪歯科大学Osaka Dental University博士（歯学）Tooth surfaces are exposed to saliva, food and drink, and microorganisms in the oral cavity. Adhesions are formed on the tooth surface by saliva-derived components, microorganisms, and microbial products. These deposits can cause tooth discoloration, staining, caries, or periodontal disease. The acquired film is one of the adherents of the teeth and is composed mainly of organic nitrogen compounds found in saliva. While the acquired film protects the tooth structure from drying and demineralization, it can also become a springboard for bacteria to grow if the acquired film remains attached to the tooth surface for a long period of time. In addition to the purpose of preventing dental disease, removal of dental adhesions is important when prosthetic or orthodontic devices are bonded to teeth. Thus, the removal of acquired coatings is important in oral care and clinical practice. Therefore, it is necessary to accumulate research on the formation and removal of artificially acquired coatings on the tooth surface. In this study, we attempted to form an artificial acquired film by using two organic nitrogen compounds and attaching them to the surface of bovine anterior tooth enamel, observing the presence of nitrogen on the enamel that is not removed by rinsing and the changes in its microstructure.doctoral thesi
Fusobacterium nucleatum亜種分離株におけるバイオフィルム形成能力の比較解析
Get PDF大阪歯科大学Osaka Dental University博士（歯学）The oral commensal Fusobacterium nucleatum (Fn) is critical in biofilm development. Although differences in biofilm formation among subspecies have been reported, detailed analyses of the isolates are scarce. The present study evaluated biofilm formation in four Fn subspecies (Fn animalis, Fn nucleatum, Fn polymorphum, and Fn vincentii) using crystal violet staining and fluorescence microscopy on novel cultivation platforms. The type strains showed notable variability, with Fn nucleatum and Fn vincentii forming strong biofilms, whereas Fn animalis and Fn polymorphum were weaker. The Isolates displayed a broad range of biofilm capacities, in some instances surpassing those of the type strains. Our findings demonstrated significant heterogeneity in biofilm formation across Fn subspecies, thus providing insights into their ecological and disease-associated dynamics.doctoral thesi
Association between frailty and subjective and objective sleep indicators in Japanese community-dwelling older adults.
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Computed tomographic analysis of mandibular tori and their relationship to remaining teeth.
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