Universitas Setia Budi Surakarta: USB e-journal
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NIAT PERILAKU MENGGUNAKAN APLIKASI KESEHATAN GRAB HEALTH SELAMA MASA PANDEMIK COVID-19
This research aims to examine the effect of behavioural intention using the Grab Health application during the Covid-19 pandemic. Variables that support the formation of behavioral intentions are attitudes. The formation of attitudes in use is caused by perceived enjoyment, social influence, and perceived vulnerability in using Grab Health applications. Data was obtained from questionnaires were distributed to the general public who use health applications Grab Health. The sampling technique used is non probability sampling, that is convenience sampling technique. The sample used in the study was 200 respondents who used the health applications Grab Health. Hypothesis testing is done by the Structural Equation Modeling (SEM) analysis method using the AMOS program. The results of this research indicate that attitudes have a significant effect on behavioral intentions, positive perceptions of perceived enjoyment are significant to attitudes, social influences have a significant influence on attitudes, and perceptions of vulnerability do not significantly influence attitudes in the use of health applications Grab Health
Peningkatan Kualitas, Pembuatan Selai Dan Biskuit Tepung Ubi Jalar Pada Kelompok Tani Mulyo Dusun Kramen Desa Pablengan Kecamatan Matesih Kabupaten Karanganyar
Matesih has a lot of sweet potates, especially during the great harvest time. The post-harvest treatment need to be done such as flour making and product diversification (bisucit and jam). The method used in this study is counseling, demonstrations, training and mentoring. The counseling was carried out through discussion through the whatsapp group with the Mulyo Farmer Group, considering the Covid-19 Pandemic. There were 19 members of the whatsapp group (who had cellphones), they were trainers to teach the rest who did not join the whatsapp group (did not have cellphones). Small groups of 4 were made consisting members whose house were close each other. Demonstrations and training were carried out by each group with the practice of making jam and biscuits made from sweet potato flour. They made based on the training videos, then uploaded their practice videos to the whatsapp group. The sweet potato biscuits and jam produced from the training were evaluated by external parties, including bakery owners, testers with a culinary background, and product display exhibitors for the 24th Anniversary of FMIPA UNS. The results of the evaluation were used to improve the sweet potato biscuit and jam made by the Foster Partners. Biscuit and jam that have been improved were helped to find the market places, including Fanny Bakery Palur, Roti Boy Jaten, Pasar Gede, and a Gethuk Semar gift shop, as well as the FMIPA UNS canteen. Furthermore, the group will be accompanied to register the PIRT permit before it is sold. The outputs that had been achieved based on this activity were articles publication, videos on how to make sweet potato jam and biscuits and videos of product exhibitions.Ubi jalar di Kecamatan Matesih cukup berlimpah, apalagi di saat panen raya. Penanganan pascapanen umbi ubi jalar perlu dilakukan antara lain dengan pembuatan tepung dan diversifikasi produk olahannya antara lain biscuit dan selai. Metode pelaksanaan yang dilakukan adalah melalui penyuluhan, demonstrasi, pelatihan, dan pendampingan. Penyuluhan dilakukan dengan diskusi melalui wa grup bersama Kelompok Tani Mulyo, mengingat masih masa Pandemi covid 19. Anggota wa grup berjumlah 19 orang (yang punya hp) dan anggota grup sebagai pelatih untuk mengajari yang lain yang tidak ikut wa grup (tidak punya hp). Dibuat kelompok kecil sebanyak 4 kelompok yang rumahnya berdekatan. Demonstrasi dan pelatihan dilakukan tiap kelompok dengan praktik pembuatan selai dan biskuit berbahan dasar tepung ubi jalar yang mereka buat. Mereka membuat berdasarkan contoh dari video pelatihan, kemudian mengunggah video praktek mereka ke wa grup. Biskuit dan selai ubi jalar yang dihasilkan dari pelatihan tersebut dievalusi oleh pihak luar, antara lain pemilik Bakery, tester yang berlatar belakang pendidikan tata boga, dan peserta pameran display produk dalam rangka Dies ke 24 FMIPA UNS. Hasil evalusi digunakan untuk memperbaiki biskuit dan selai ubi jalar yang dibuat Mitra Binaan. Biskuit dan selai yang sudah diperbaiki kualitasnya didampingi untuk dicarikan tempat pemasaran antara lain ke Fanny Bakery Palur, Roti Boy Jaten, Pasar Gede, dan toko oleh-oleh Gethuk Semar, serta kantin FMIPA UNS. Selanjutnya akan didampingi untuk mendaftarkan ijin PIRT sebelum dijual. Luaran yang sudah dicapai dalam kegiatan ini adalah artikel publikasi, video cara pembuatan selai dan biskuit ubi jalar serta video pameran produk.
Kata kunci : ubi jalar, tepung, selai, biskui
Analysis of Interleukin-4 in Thrombocytopenia Autoimmune Patients
Thrombocytopenia is a disease characterized by a decreased platelet count. Some of the causes are decreased platelet production, increased platelet use, such as due to infection, and autoimmune causes, namely the loss of tolerance of the immune system to self-antigens on the surface of the platelets and megakaryocytes marked with a platelet count <100,000 / μL and based on the pathomechanism classified as primary Immune Thrombocytopenia (ITP) and secondary, as well as several other causes. IL-4, one of the cytokines produced by Th2 which stimulates B cells to increase antibody production. The aim of this study was to compare IL-4 levels in primary ITP patients and non-primary ITP tombocytopenia. This study involved 30 primary ITP subjects and 30 non-ITP primary tombocytopenia subjects obtained based on data medical records, examination of IL-4 cytokine levels by the ELISA method. The results of this study that the IL-4 levels of the primary non ITP tombocytopenia subject group were higher than the primary ITP subject group, which means that there were differences in IL-4 levels in the primary ITP subject group and the non-ITP primary tombocytopenia subject group.Thrombocytopenia is a disease characterized by a decreased platelet count. Some of the causes are decreased platelet production, increased platelet use, such as due to infection, and autoimmune causes, namely the loss of tolerance of the immune system to self-antigens on the surface of the platelets and megakaryocytes marked with a platelet count <100,000 / μL and based on the pathomechanism classified as primary Immune Thrombocytopenia (ITP) and secondary, as well as several other causes. IL-4, one of the cytokines produced by Th2 which stimulates B cells to increase antibody production. The aim of this study was to compare IL-4 levels in primary ITP patients and non-primary ITP tombocytopenia. This study involved 30 primary ITP subjects and 30 non-ITP primary tombocytopenia subjects obtained based on data medical records, examination of IL-4 cytokine levels by the ELISA method. The results of this study that the IL-4 levels of the primary non ITP tombocytopenia subject group were higher than the primary ITP subject group, which means that there were differences in IL-4 levels in the primary ITP subject group and the non-ITP primary tombocytopenia subject group
DINAMIKA PERILAKU MENOLONG BYSTANDER PADA KORBAN BULLYING DI SEKOLAH
School is a place to construct the character and personality of student. In the current status qou, the teaching and learning process in the school is often misslead with the development of its student, one of the behavior is bullying. The case of bullying is not only involved the perpetrator and victim but also the bystander. This 3rd actor can determine whether the act of bullying can be dismissed or not. This study aimed to know the role of bystander while the act of bullying occurs.
The purpose of this study was to analyze and discuss the patterns of bystander's helping behavior to the victims of intimidation. The method utilized in this study was a qualitative design with open ended questioner. The data analysis of this study was using the descriptive analysis. The stages consist of research analyze, library research, data collection which used to analyze the data by describing or analyzing the collected data, determining the categories, and to draw the conclusions. The participants of this study were 150 students of Surakarta X Vocational High School who has the similar characteristics as observers.
The results of this study found that the actions taken by bystander when encountering bullying in schools were reporting to the teachers (42.67%), suggesting the victims to avoid the perpetrators (30%), separating the actors (16%), and helping victim to fight offender (11.33%).Sekolah adalah tempat untuk membangun karakter dan kepribadian siswa. Dalam proses belajar mengajar di sekolah sering digaduhkan dengan perkembangan siswanya, salah satu perilakunya adalah bullying. Kasus ini tidak hanya melibatkan pelaku dan korban saja tetapi juga bytsander. Bystander ini dapat menentukan apakah tindakan bullying dapat dihentikan atau tidak.
Penelitian ini bertujuan untuk mengetahui peran bystander saat terjadi bullying. Metode yang digunakan dalam penelitian ini adalah desain kualitatif dengan kuesioner terbuka. Analisis data penelitian ini menggunakan analisis deskriptif. Tahapan – tahapan tersebut terdiri dari analisis penelitian, penelitian kepustakaan, pengumpulan data yang digunakan untuk menganalisis data dengan menggambarkan atau menganalisis data yang dikumpulkan, menentukan kategori, dan untuk menarik kesimpulan. Partisipan penelitian ini adalah 150 siswa SMA X Surakarta yang memiliki karakteristik sama dengan bystanders.
Hasil penelitian ini menemukan bahwa Tindakan yang dilakukan oleh pengamat ketika menghadapi intimidasi disekolah melaporkan kepada guru (42,67 %), menyarankan para korban untuk menghindari pelaku (30 %), memisahkan pelaku (16 %), dan membantu korban untuk melawan pelaku (11,33 %)
ANALISIS ENAM FAKTOR PREVENTIF PERILAKU SEKSUAL BERISIKO REMAJA SEKOLAH MENENGAH PERTAMA GENERASI PLATINUM
ABSTRACT. The risk-taking issue of sexual behavior at a young age often leads to bad damage for the teenager and its surroundings when viewed as an asset of a nation to engage in such an aspect of development, the preoccupation of sexual behavior must be overcome by involving a number of important factors among famlies, school, peers, religiousity, social media, and local cultural values. The aims of the discussion, then is to recognize the simultaneous impact of six preventive factors : risky sexual behavior on the teenager, and individual relationships with adolescent risky sexual behavior. The methods used are double-regression quantitative and the correlation by Karl Pearson. Participant engaged by 150 students (sevent – nine grade) with saturated technique sampling. The scales that used are the parent-adolescent relationship scale (Hair, dkk., 2005), quality of school life scale (Eptein dan McPartland, 1998), CAYCI peer relationship scale : middle/high school student version (Butcher, dkk., 2016), the adolescent religious coping scale (Bjorck, 2009), outside and inside school media of behavior scale (Lu, dkk., 2018), cultural intelligence scale (Earley dan Ang, 2003), and the scale of risky sexual behavior. The result of the research hypothesis is accepted, which means there are simultaneous effect of six factors on adolescent risky sexual behavior with a value of 9,179 and of significance = 0,000, and there is a significant negative relationship between each factor and the risky sexual behavior of adolescents. The value of the six preventive factors is in high categroies, and the risky sexual behavior of adolescents is in a low category. This result indicates that six specific factors can be established as a primary mediator incoping with sexual behavior at risk for the adolescence of the platinum generatio
the Faktor-Faktor yang Berpengaruh terhadap Adverse Drug Reaction pada penggunaan Obat Anti Tuberkulosis
Adverse Drug Reaction (ADR) in the treatment of tuberculosis can reduce the quality of life and compliance of patients, long-term treatment has a risk of ADR, to prevent dangerous ADRs need to be monitored properly, the predictors that affect ADR are very important to be sought as an effort to prevent the incidence ADR.
This study was a cross-sectional study conducted on pulmonary tuberculosis patients at the Public Health Center (PKM) of Bantul Regency Yogyakarta, inclusion criteria were patients who received fixed-dose combination tuberculosis (KDT), age> 17 years old, ADR monitoring was carried out since the month of two treatments up to the 6th month by interview method for each control patient to the PKM. Data processing was performed by multinomial regression multivariate tests.
The results showed that ADR occurred in 58% of the old age group; 51.8% of the middle age group and 50% of the young age group, there was no significant effect of age on ADR in this study. Based on sex, ADR occurred in 58.5% of men, and 47.3% of women, with no significant effect of gender on ADR. Based on BMI, ADR occurred in the underweight, normal, and overweight groups with a percentage of 78%, 26%, and 40% there was a significant influence between BMI and the incidence of ADR, p-value 0.01 OR = 7,650 (2,350-24,898) CI = 95 %. Based on the BTA ADR group occurred in the positive and negative BTA groups with a percentage of 52% and 62%, there was no significant effect between the BTA and the ADR incidence
Key words : Adverse Drug Reaction, Tuberculosis, Fixed-dosed combination-Antituberculosis Drug (FDC)Adverse Drug Reaction (ADR) pada pengobatan tuberkulosis dapat menurunkan kualitas hidup maupun kepatuhan pasien, pengobatan jangka panjang memiliki risiko timbulnya ADR, untuk mecegah ADR yang berbahaya perlu dilakukan monitoring dengan baik, faktor-faktor prediktor yang mempengaruhi ADR sangat penting dicari sebagai upaya mencegah kejadian ADR.
Penelitian ini merupakan penelitian cross sectional yang dilakukan pada pasien tuberkulosis paru di Pusat Kesehatan Masyarakat (PKM) Kabupaten Bantul Yogyakarta, kriteria inklusi adalah pasien yang mendapat obat tuberkulosis kombinasi dosis tetap (KDT),usia >17 tahun, monitoring ADR dilakukan sejak bulan ke-dua pengobatan hingga bulan ke-6 dengan metode wawancara setiap pasien kontrol ke PKM. Pengolahan data dilakukan dengan uji multivariate regresi multinomial.
Hasil penelitian menunjukkan bahwa ADR terjadi pada 58% kelompok usia tua; 51,8% kelompok usia menengah dan 50% kelompok usia muda, tidak ada pengaruh signifikan usia terhadap ADR pada penelitian ini. Berdasar jenis kelamin, ADR terjadi pada 58,5% laki-laki, dan 47,3 % perempuan, tidak terdapat pengaruh signifikan gender terhadap ADR. Berdasar BMI, ADR terjadi pada kelompok underweight, normal, dan overweight dengan persentase 78%,26%,dan 40% terdapat pengaruh signifikan antara BMI dengan kejadian ADR, p value 0,01 OR=7,650 (2,350-24,898) CI=95%. Berdasar kelompok BTA ADR terjadi pada kelompok BTA positif dan negative dengan persentase 52% dan 62%, tidak ada pengaruh signifikan antara BTA dengan kejadian ADR
Kata kunci : Adverse Drug Reaction, Tuberkulosis, Kombinasi Dosis Tetap-Obat Antituberkulosis (KDT)
 
Effect Effect of Black Rice Bran on the Pharmacokinetics Profile of Glibenclamide in Hyperglycemic Rats
Black rice bran (BBH) which contains anthocyanins has the ability to lower blood sugar. In therapy diabetes mellitus (DM) it is possible that BBH is used together with the oral antidiabetic Glibenclamide (Gli). Glibenclamide, a weak acid, is well absorbed in the gastrointestinal tract. The absorption of BBH is also good under acidic conditions. So, it is necessary to study the pharmacokinetic interactions between Gli and BBH.
The study was designed using a one-way completely randomized design of ten (10) hyperglycemic rats, divided into two groups. Group I rats received Gli 5 mg / kgBW treatment, and group II received Gli 5 mg/kgBW along with BBH 50 mg / kgBW. Sampling was carried out at 1, 2, 4,6, 8 and 24 hours after treatment. Gli levels in the blood were determined by Liquid Chromatography/Mass Spectroscopy (LC/MS).
The results showed that in the absorption phase, giving BBH with Gli did not affect the Gli profile in terms of parameters Tmax, Cmax and AUC0-inf. Likewise, in the distribution and elimination phases in terms of parameters VD, ClT and elimination half-time (t1/2). So that the provision of BBH does not affect the pharmacokinetic parameters of Gli in hyperglycemic rats.Black rice bran (BBH) which contains anthocyanins has the ability to lower blood sugar. In therapy diabetes mellitus (DM) it is possible that BBH is used together with the oral antidiabetic Glibenclamide (Gli). Glibenclamide, a weak acid, is well absorbed in the gastrointestinal tract. The absorption of BBH is also good under acidic conditions. So, it is necessary to study the pharmacokinetic interactions between Gli and BBH.
The study was designed using a one-way completely randomized design of ten (10) hyperglycemic rats, divided into two groups. Group I rats received Gli 5 mg / kgBW treatment, and group II received Gli 5 mg/kgBW along with BBH 50 mg / kgBW. Sampling was carried out at 1, 2, 4,6, 8 and 24 hours after treatment. Gli levels in the blood were determined by Liquid Chromatography/Mass Spectroscopy (LC/MS).
The results showed that in the absorption phase, giving BBH with Gli did not affect the Gli profile in terms of parameters Tmax, Cmax and AUC0-inf. Likewise, in the distribution and elimination phases in terms of parameters VD, ClT and elimination half-time (t1/2). So that the provision of BBH does not affect the pharmacokinetic parameters of Gli in hyperglycemic rats
ALOKASI BELANJA MODAL KABUPATEN DAN KOTA DITINJAU DARI INDIKATOR KINERJA KEUANGAN DAERAH
This study aims to analyze the capital expenditure allocation of district and municipal as seen from local financial performance indicators. The data in this study is secondary data obtained from regional financial reports that have been audited by BPK RI. The variables that are expected to influence the allocation of capital expenditure in this study are the Regional Financial Independence, locally-generated revenue Effectiveness, Financial Efficiency, Debt Service Coverage Ratio, and Harmony of Expenditure. The sample in this study using districts and cities in East Java Province and selected based on purposive sampling method with five years observation period and using data analysis method used is multiple linear regression. The results showed that there are three influential variables: Regional Financial Independence, Local Financial Efficiency, and Harmony of Expenditure, while the other two variables namely locally-generated revenue Effectiveness and Debt Service Coverage Ratio have no effect on capital expenditure allocation
PENGARUH PERSEPSI POLITIK ORGANISASIONAL TERHADAP KEPUASAN KERJA YANG DIMODERASI KETRAMPILAN POLITIK
The purpose of this study is to examine the effect of organizational political perceptions on job satisfaction moderated by political skills. This research is important because it is able to examine the significance of the relationship between organizational political perceptions and political skills on job satisfaction. This research uses survey research methods through questionnaires. The object of research is all hospital employees in the city of Surakarta with a sample of 159 respondents. Sampling in this study using the probability sampling method. The analytical tool used in this study is simple linear regression while the moderating analysis tool uses regression analysis tools. The results showed H1 had a significant relationship while H2 did not have a significant relationship. These results give the sense that organizational political perceptions affect job satisfaction. While political skills as a moderator between organizational political perceptions do not affect job satisfaction
Different of Cholesterol Levels in Cigarette Smokers and Electronic Cigarette
Smoking causes an increase in cholesterol in the blood. It is well known that tobacco contains nicotine has a considerable influence on the increase of blood lipid levels. Normally, lipids play an important role in all aspects of biological life, but excessive cholesterol causes changes in lipid composition, induces ROS formation and lipid oxidation. This process can also cause damage to proteins and DNA, changing cellular function, which causes tissue damage. This research using analytic survey, with analytic cross sectional design with 30 subjects. The mean cholesterol level between tobacco smokers is 210.0 mg / dl and electric smokers is 123.73 mg / dl. The average difference in cholesterol levels among smokers was tested using One way ANOVA, p value = 0.000 (p <0.05). The cholesterol level of the tobacco smoker group was significantly higher when compared to the electronic smoker group.Smoking causes an increase in cholesterol in the blood. It is well known that tobacco contains nicotine has a considerable influence on the increase of blood lipid levels. Normally, lipids play an important role in all aspects of biological life, but excessive cholesterol causes changes in lipid composition, induces ROS formation and lipid oxidation. This process can also cause damage to proteins and DNA, changing cellular function, which causes tissue damage. This research using analytic survey, with analytic cross sectional design with 30 subjects. The mean cholesterol level between tobacco smokers is 210.0 mg / dl and electric smokers is 123.73 mg / dl. The average difference in cholesterol levels among smokers was tested using One way ANOVA, p value = 0.000 (p <0.05). The cholesterol level of the tobacco smoker group was significantly higher when compared to the electronic smoker group