Universitas Setia Budi Surakarta: USB e-journal
Not a member yet
892 research outputs found
Sort by
Uji Efektifitas Gel Ekstrak Sambung Nyawa (Gynura Procumbens (Lour.)Merr.) Terhadap Penyembuhan Luka Pada Kelinci Hiperglikemia
Get PDFHyperglycemia can inhibit the wounds healing process. Giving life-sustained leaf extract gel (Gynura procumbens (Lour.) Merr.) Is one of the options. The long-term goal of this study is to prove that the gel extract (Gynura procumbens (Lour.) Merr.) Leaf extract gel is able to heal wounds in hyperglycemic test animals. The specific target to be achieved is to obtain efficacious natural medicines to prevent the occurrence of diabetic wounds and to know the effective dosage of gel extract extract (Gynura procumbens (Lour.) Merr.) As a cure for diabetic wounds. This study used 5 white rabbits. Testing is done by making a wound on the back of DM alloxan-induced test animals. Wound healing activity is seen by dividing the backs of test animals into 5 parts which are treated according to their groups. The treatment group and the positive control group were applied with gel twice a day for 9 days and measured the length of the wound on days 1, 3, 5, 7, and 9. Diabetic wound healing activity was shown by calculating the wound length of each treatment and analyzed with the Anova test one way with a 95% confidence level. The results of the study showed that the formulation of life grafting gel extract based on CMC Na had good physical quality test results such as organoleptic color test according to the color of the extract, distinctive aroma of the life span leaf extract, viscous, homogeneous appearance, had a pH of 6. For the dispersion test , adhesion, and viscosity, each meets the desired requirements. The wound healing activity test showed that the grafted leaf extract with a concentration of 5% was able to heal the best, with a percentage of wound healing of 67.00%.Kondisi hiperglikemia bisa menghambat proses penyembuhan luka. Pemberian gel ekstrak daun sambung nyawa (Gynura procumbens (Lour.)Merr.) menjadi salah satu pilihannya. Tujuan jangka panjang penelitian ini adalah membuktikan gel ekstrak daun sambung nyawa (Gynura procumbens (Lour.)Merr.) mampu menyembuhkan luka pada hewan uji yang diinduksi aloksan. Target khusus yang ingin dicapai adalah memperoleh obat alam berkhasiat mencegah terjadinya luka diabetik dan mengetahui dosis efektif gel ekstrak daun sambung nyawa (Gynura procumbens (Lour.)Merr.) sebagai penyembuh luka pada kondisi hiperglikemia. Penelitian ini menggunakan kelinci putih sebanyak 5 ekor. Pengujian dilakukan dengan membuat luka pada punggung hewan uji DM yang diinduksi aloksan. Aktivitas penyembuhan luka dilihat dengan membagi punggung hewan uji menjadi 5 bagian yang diberi perlakuan sesuai kelompoknya. Kelompok perlakuan dan kelompok kontrol positif dioles dengan gel 2 x sehari selama 9 hari dan dilakukan pengukuran panjang luka pada hari ke 1, 3, 5, 7, dan 9. Aktivitas penyembuh luka diabetik ditunjukkan dengan cara menghitung panjang luka masing-masing perlakuan dan dianalisa dengan uji Anova satu jalan dengan taraf kepercayaan 95%. Hasil dari penelitian menunjukkan bahwa formulasi gel ekstrak daun sambung nyawa dengan basis CMC Na memiliki hasil uji kualitas fisik yang baik seperti uji organoleptis warna sesuai warna ekstrak, aroma khas ekstrak daun sambung nyawa, penampilan kental, homogen, memiliki pH 6. Untuk uji daya sebar, daya lekat, dan viskositas, masing-masing memenuhi persyaratan yang diinginkan. Uji aktivitas penyembuhan luka menunjukkan bahwa kelompok gel ekstrak daun sambung nyawa dengan konsentrasi 5% mampu menyembuhkan paling baik, dengan persentase penyembuhan luka sebesar 67,00%
Sistematik Review Aktivitas Buah Pare (Momordica charantia L.) Terhadap Target Molekuler Antidiabetes
Get PDFDiabetes mellitus (DM) is a chronic disease that occurs either when the pancreas does not produce enough insulin, or when the body cannot effectively use the insulin it produces. The purpose activity of bitter melon fruit against molecular targets antidiabetic in literatre review.
Analysis and systematic web search reviews were carried out on the research literature related to bitter melon which is used for DPP4, PTP1B, α-glucosidase, and increasing GLUT4 levels. The data were collected from several journals with inclusion criteria. The data were extracted and synthesized.
The charantin, cucurbitacin, dan momordicoside D compound from bitter melon fruit has activating the TGR5 and GLP1 receptor simultaneously inhibiting DPP4. The cucurbitane 25-O-methylkaraviagein D the of bitter melon fruit has inhibitory activity against the PTP1B enzyme which is associated with the presence of –OH, The 3β,7β,25-trihydroxycucurbita-5,23(E)-dien-19-al, charantal, charantoside XI, dan 25ξ- isopropenylchole-5, 6-ene-3-O- D-glukopiranosida α-glucosidase predicted to have inhibitory activity of binding to the active side of the protein. The vicine, polypeptide-p, 5-,19-epoxy-3-, 25-dihydroxycucurbita-6,23 (E) -diene dan 3-7-,25-trihydroxycucurbita-5,23 (E)-dien-19-al can increase the amount of GLUT4 on the cell surface.Diabetes melitus (DM) adalah penyakit kronis yang terjadi baik ketika pankreas tidak menghasilkan cukup insulin, atau ketika tubuh tidak dapat secara efektif menggunakan insulin yang dihasilkannya. Tujuan mengetahui aktivitas buah pare terhadap target molekuler antidiabetes secara literature review.
Analisis dan tinjauan pencarian web sistematis dilakukan pada literatur penelitian yang berkaitan dengan buah pare digunakan untuk aktivitas DPP4, PTP1B, α-glukosidase, dan peningkatkan kadar GLUT4. Data dikumpulkan dari beberapa jurnal dengan kriteria inklusi. Data diekstraksi dan data sintesis.
Studi literatur review senyawa charantin, cucurbitacin, dan momordicoside D secara bersamaan mengaktivasi reseptor TGR5 dan GLP1 untuk menghambat DPP4, senyawa cucurbitane 25-O-methylkaraviagein D dikaitkan dengan keberadaan –OH memiliki aktivitas penghambatan terhadap enzim PTP1B, senyawa 3β, 7β, 25-trihydroxycucurbita-5,23(E)-dien-19-al, charantal, charantoside XI, dan 25ξ- isopropenylchole-5, 6-ene-3-O- D-glukopiranosida diprediksi memiliki afinitas mengikat sisi aktif protein sehingga menghambat α-glukosidase, dan senyawa charantin, vicine, polypeptide-p, 5-,19-epoxy-3-, 25-dihydroxycucurbita-6,23 (E) -diene dan 3- 7-, 25-trihydroxycucurbita-5,23 (E)-dien-19-al. dapat meningkatkan jumlah GLUT4 pada permukaan sel
Pembagian Masker Dan Hand Sanitizer Gratis Sebagai Upaya Pencegahan Terinfeksi Covid-19
Get PDFCOVID-19 or Corona Virus Disease 2019 is a virus that causes diseases ranging from mild to severe symptoms. There are at least two types of coronavirus that are known to cause diseases that can cause severe symptoms such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). Coronavirus Disease (COVID-19) is a new type of virus that has never been previously identified in humans. Coronaviruses are zoonotic (transmitted between animals and humans). It is common for coronavirus transmission to pass through droplets of infected patients and through direct contact with contaminated surfaces. So to protect ourselves, we need to have a healthy lifestyle with a regular diet, drink enough water, exercise regularly, get adequate rest, and maintain overall body hygiene, namely bathing every day, washing hands with soap or hand sanitizer every time. will eat/drink and come out of the bathroom.COVID-19 atau Corona Virus Disease 2019 merupakan virus yang menyebabkan penyakit mulai dari gejala ringan sampai berat. Ada setidaknya dua jenis coronavirus yang diketahui menyebabkan penyakit yang dapat menimbulkan gejala berat seperti Middle East Respiratory Syndrome (MERS) dan Severe Acute Respiratory Syndrome (SARS). Coronavirus Disease (COVID-19) adalah virus jenis baru yang belum pernah diidentifikasi sebelumnya pada manusia. Virus corona adalah zoonosis (ditularkan antara hewan dan manusia). Lazimnya penularan coronavirus dapat melalui droplet pasien yang terinfeksi dan melalui kontak langsung dengan permukaan yang terkontaminasi. Sehingga untuk melindungi diri, kita perlu melakukan pola hidup sehat dengan pola makan teratur, minum air putih yang cukup, berolahraga rutin, istirahat yang cukup, dan menjaga kebersihan tubuh secara keseluruhan, yaitu mandi setiap hari, mencuci tangan dengan sabun atau hand sanitizer setiap kali akan makan/minum dan keluar dari kamar mandi
PENGARUH KEPEMIMPINAN AUTENTIK TERHADAP MANAJEMEN KESALAHAN YANG DIMEDIASI OLEH MODAL PSIKOLOGIS
Get PDFThis study aims to test psychological capital mediates the relationship between authentic leadership and error management. Authentic leadership on psychological capital, psychological capital on error management, and authentic leadership on error management. The data were obtained from the questionnaires distributed to Hospital employees Jiwa Surakarta and Hospital PKU Muhammadiyah Surakarta. The sampling technique used was cluster sampling with 159 respondents from the hospital employees population. The hypothesis test was used by using regretion test the SPSS 18 program. The results of the study indicate that the authentic leadership significantly affect on the error management, psychological capital significantly affect error management, authentic leadership significantly affect psychological capital, so that the psychological capital is strongly reinforced by the relationship between authentic leadership and error management.
Keywords: psychological capital, authentic leadership, error managementThis study aims to test psychological capital mediates the relationship between authentic leadership and error management. Authentic leadership on psychological capital, psychological capital on error management, and authentic leadership on error management. The data were obtained from the questionnaires distributed to Hospital employees Jiwa Surakarta and Hospital PKU Muhammadiyah Surakarta. The sampling technique used was cluster sampling with 159 respondents from the hospital employees population. The hypothesis test was used by using regretion test the SPSS 18 program. The results of the study indicate that the authentic leadership significantly affect on the error management, psychological capital significantly affect error management, authentic leadership significantly affect psychological capital, so that the psychological capital is strongly reinforced by the relationship between authentic leadership and error management.
Keywords: psychological capital, authentic leadership, error managemen
The Comparison of Mycobacterium tuberculosis Detection using Molecular Rapid Test and Immunochromatography in Patients Suspected of Having Tuberculosis in Pangkajene and Kepulauan Regencies
Get PDFMycobacterium tuberculosis is an acid-resistant bacterium that causes tuberculosis and can be detected using a variety of methods. This study aimed to determine the comparison of the detection results of Mycobacterium tuberculosis using the molecular rapid test (MRT) and immunochromatographic method. This research was conducted at Batara Siang Hospital, Pangkajene, and Kepulauan Regencies, in July-September 2019 using 100 samples. This study is cross-sectional research, applying the chi-square test for analysis. The results of statistical tests revealed a significant difference between the results of tests using molecular rapid tests and immunochromatography (<0.001). The sensitivity, specificity, positive probability value, negative probability value, and accuracy of the immunochromatography method against the molecular rapid test (MRT) were 91.3%, 100%, 100%, 93.1%, and 96%, respectively.Mycobacterium tuberculosis is an acid-resistant bacterium that causes tuberculosis and can be detected using a variety of methods. This study aimed to determine the comparison of the detection results of Mycobacterium tuberculosis using the molecular rapid test (MRT) and immunochromatographic method. This research was conducted at Batara Siang Hospital, Pangkajene, and Kepulauan Regencies, in July-September 2019 using 100 samples. This study is cross-sectional research, applying the chi-square test for analysis. The results of statistical tests revealed a significant difference between the results of tests using molecular rapid tests and immunochromatography (<0.001). The sensitivity, specificity, positive probability value, negative probability value, and accuracy of the immunochromatography method against the molecular rapid test (MRT) were 91.3%, 100%, 100%, 93.1%, and 96%, respectively
Peramalan Produksi Beras di Provinsi Jawa Tengah
Get PDFThe availability of local rice needs to be predicted to meet the demand for rice supply in Indonesia. Central Java, as the third largest rice producer in Indonesia, is one of the pillars of national rice demand. The amount of food production in Indonesia is an important factor in determining the right food supply. Forecasting rice production in Central Java is necessary to determine future food conditions. The purpose of this research is to develop a forecast model for rice production in Central Java province and to find out the estimated rice production in Central Java Province in the next 5 years. The time series forecasting method was used in this study. The data used in this study are data on rice production from 1993 to 2020. From the results of the Auto Correlation Function (ACF) test, it is known that the production data has a trend data pattern. The method used in this study is the double exponential smoothing method with two parameters (Holt's Methods). The optimal forecasting model is obtained with the help of solver software in Microsoft Excel. By using the help of the Microsoft Excel solver, the optimal constant value α is 0,767 and β is 0,412 with a Mean Absolute Precentage Error value of 4,82%. Forecasting results from 2021 to 2025 are known to decline every year. The average decline in rice production in the next 5 years is estimated at 4,4% per year.
Keywords: rice, exponential smoothing, Central Java, forecastingKetersediaan beras lokal perlu diprediksi untuk memenuhi kebutuhan pasokan beras di Indonesia. Jawa Tengah sebagai penghasil beras terbesar ketiga di Indonesia merupakan salah satu penopang kebutuhan beras nasional. Besarnya produksi pangan di Indonesia menjadi faktor penting dalam penentuan persediaan pangan yang tepat. Peramalan produksi beras di Jawa Tengah menjadi diperlukan untuk mengetahui kondisi pangan ke depan. Tujuan penelitian ini adalah untuk mengembangkan model peramalan produksi beras di provinsi Jawa Tengah dan mengetahui perkiraan produksi beras di Provinsi Jawa Tengah 5 tahun ke depan. Metode time series forecasting digunakan dalam penelitian ini. Data yang digunakan dalam penelitian ini adalah data hasil produksi beras dari tahun 1993 hingga tahun 2020. Dari hasil uji fungsi auto korelasi diketahui bahwa data produksi memiliki pola data tren. Metode yang digunakan dalam penelitian ini adalah metode double exponential smoothing dengan dua parameter (Holt’s Methods). Model peramalan yang optimal didapatkan dengan bantuan software solver pada Microsoft Excel. Dengan menggunakan bantuan solver Microsoft Excel diperoleh nilai konstanta optimal α sebesar 0,767 dan β sebesar 0,412 dengan nilai Mean Absolute Precentage Error sebesar 4,82%. Hasil peramalan dari tahun 2021 hingga 2025 diketahui menurun setiap tahunnya. Rata-rata penurunan produksi beras dalam 5 tahun ke depan diperkirakan sebanyak 4,4% per tahunnya.
Kata kunci: beras, exponential smoothing, Jawa Tengah, peramala
HUBUNGAN ANTARA PENGGUNAAN MEDIA SOSIAL DENGAN KESEPIAN DAN PERILAKU PERBANDINGAN SOSIAL
Get PDFThe development of social media is increasingly massive, forcing more and more interactions from its users. So far, studies on the influence of the use of social media only refer to one particular social media. This study aims to look at the intensity of social media use with loneliness and social comparisons. The sample in this study were social media users using random sampling with the help of google form. The intensity of social media use is measured using the Intensity scale of Social Media Use which has dimensions of attention, appreciation, duration and frequency, while to measure using the UCLA-3 scale, and social comparison is measured using the IOWA, the results show a positive relationship between intensity of social media use. with loneliness and social comparisons. Thus, the higher the intensity of the use of social media, the more it will cause loneliness and make social comparisons to its users.
Perkembangan media sosial yang semakin masif, memaksa interaksi yang semakin bertambah dari penggunanya. Selama ini kajian tentang pengaruh penggunaan media sosial hanya merujuk pada salah satu media sosial tertentu. Penelitian ini hendak melihat intensitas penggunaan media sosial dengan kesepian dan perbandingan sosial. Sampel dalam penelitian ini adalah pengguna media sosial dengan teknik pengambilan dengan menggunakan random sampling dengan bantuan google form. Intensitas penggunaan media sosial diukur dengan menggunakan skala Intensitas Penggunaan Medsos yang memiliki dimensi perhatian, penghayatan, durasi dan frekuensi, sedangkan untuk mengukur menggunakan Skala UCLA-3, dan perbandingan sosial diukur menggunakan IOWA, Hasil penelitian menunjukkan ada hubungan yang positif antara Intensitas penggunaan media sosial dengan kesepian dan perbandingan sosial. Dengan demikian semakin tinggi intensitas penggunaan media sosial maka akan semakin menimbulkan kesepian dan melakukan perbandingan sosial penggunanya.
 
Teknologi Olahan Umbi Gadung Menjadi Keripik Gadung yang Awet, Bercita Rasa Dan Bernilai Ekonomis Tinggi di Industri Kecil Menengah
Get PDFIKM Zoefa Snack was founded in 2017 and has 5 workers consisting of housewives in Dukuh Wetan Pituruh Purworejo, this IKM has a business and production activities for various processed snacks whose superior products are gadung tubers including various flavors of crackers and gadung chips. However, the marketing of this product is still limited to fulfill the markets of Purworejo and Yogyakarta Regencies. Some of the existing problems are non-uniform quality, no information on nutritional value and HCN levels, quality management and food safety have not been implemented and some products do not have PIRT and halal labels. Therefore, the processed gadung tuber product that is produced is carried out by efforts to improve processing, packaging, labeling and registration of PIRT and halal labels so that it will increase the economic value of the product and can be used as a business opportunity for partners. The processed gadung product that is transferred is the result of research by the Proposer Team that has carried out counseling, practice and production assistance. Partners are expected to increase the capacity of their products and products with better quality with attractive packaging and labels, have P.IRT and MUI halal labels so that they are more durable, have high selling value and have a wider marketing reach. The impact can further increase community income and popularize gadung chips as a superior product of Pituruh, a region rich in gadung tubers.IKM Zoefa Snack didirikan Tahun 2017 memiliki 5 pekerja yang terdiri dari ibu-ibu rumah tangga di Dukuh Wetan Pituruh Purworejo, IKM ini memiliki usaha dan kegiatan produksi aneka olahan makanan ringan yang produk unggulannya yaitu umbi gadung diantaranya kerupuk dan chips gadung aneka rasa. Akan tetapi pemasaran produk ini masih terbatas untuk memenuhi pasar Kabupaten Purworejo dan Yogyakarta. Beberapa permasalahan yang ada yaitu mutu tidak seragam, belum ada informasi nilai gizi dan kadar HCN, belum dilaksanakannya manajemen mutu dan keamanan pangan serta beberapa produk belum ada PIRT dan label halal. Oleh karena itu produk olahan umbi gadung yang dihasilkan ini dilakukan usaha perbaikan pengolahan, pengemasan pelabelan dan pendaftaran PIRT serta label halal sehingga akan meningkatkan nilai ekonomis produk dan dapat dijadikan sebagai peluang usaha bagi mitra. Produk olahan gadung yang ditransfer merupakan hasil penelitian dari Tim Pengusul yang telah melaksanakan penyuluhan, praktik dan pendampingan produksi. Mitra diharapkan dapat meningkatkan kapasitas produknya dan produk semakin baik kualitasnya dengan kemasan dan label yang menarik, memiliki P.IRT dan label halal MUI sehingga lebih awet, bernilai jual tinggi dan jangkauan pemasaran yang lebih luas. Dampak lebih jauh dapat meningkatkan pendapatan masyarakat dan mempopulerkan keripik gadung sebagai produk unggulan Pituruh yang merupakan daerah kaya akan umbi gadung
Pengaruh Kenyaman Pada Komunikasi Getok Tular Daring
Get PDFThis study aims to examine the effect of online consumer satisfaction on online word-of-mouth, the effect of convenience of access on online consumer satisfaction, the effect of transaction convenience on online consumer satisfaction and the effect of service convenience on online consumer satisfaction. Online word of mouth or electronic word of mouth is currently a trend that is proven to be able to influence the buying behavior of a consumer.The data in this study were obtained through questionnaires distributed to the general public. The sample used is 200. The sampling technique used is purpose sampling. Testing the validity and reliability used SPSS. Hypothesis testing is done by using SEM (Structural Equation Modeling) analysis.The results in this study indicate that the four hypotheses are supported. The online consumer satisfaction variable has a positive effect on online word-of-mouth. Access convenience variable has a positive effect on online consumer satisfaction. The transaction convenience variable has a positive effect on online consumer satisfaction. And the service convenience variable has a positive effect on online consumer satisfaction. The results of this study mean that the convenience provided by an online application will give a sense of satisfaction to the individual and be able to have a positive impact on the individual doing word-of-mouth online.This study aims to examine the effect of online consumer satisfaction on online word-of-mouth, the effect of convenience of access on online consumer satisfaction, the effect of transaction convenience on online consumer satisfaction and the effect of service convenience on online consumer satisfaction. Online word of mouth or electronic word of mouth is currently a trend that is proven to be able to influence the buying behavior of a consumer.The data in this study were obtained through questionnaires distributed to the general public. The sample used is 200. The sampling technique used is purpose sampling. Testing the validity and reliability used SPSS. Hypothesis testing is done by using SEM (Structural Equation Modeling) analysis.The results in this study indicate that the four hypotheses are supported. The online consumer satisfaction variable has a positive effect on online word-of-mouth. Access convenience variable has a positive effect on online consumer satisfaction. The transaction convenience variable has a positive effect on online consumer satisfaction. And the service convenience variable has a positive effect on online consumer satisfaction. The results of this study mean that the convenience provided by an online application will give a sense of satisfaction to the individual and be able to have a positive impact on the individual doing word-of-mouth online
Analisis Waktu Baku Pembuatan Produk Gasket di PT. Nichias Rockwool Indonesia
Get PDFNichias Rockwool Indonesia is a pioneer in heat protection materials and technology protection in various industrial sectors. PT. Nichias Rockwool Indonesia has several main products which are divided into three parts, namely rockwool, sealing gasket, and autoparts. The production process involves machines such as forming, winding, marking and so on. In order to increase production capacity, PT. Nichias Rockwool Indonesia uses a target completion time for a product. Therefore, it is necessary to calculate the standard time in the completion of the gasket assembly process. Process standard time in a company allows a uniform period of time used to complete production within a company. The measurement of working time to be carried out in this study uses the stopwatch time study method. This method is done by measuring time by observing and recording work operation times. This time data will then be calculated standard time. The number of research data is 150 data taken from selected trained operators. Factors of adjustment and allowances (allowance) using the Westinghouse method. The result of this research is that the cycle time is 21.67 seconds, the normal time is 23.62 seconds, and the standard time is 28.34 seconds. Production capacity before the standard time was only 553 gaskets per day, after calculating the standard time it increased to 889 gaskets per day or 54.97%.
Keywords: production capacity, stopwatch time study, standart timePT. Nichias Rockwool Indonesia merupakan perusahaan pelopor dalam bahan perlindungan panas dan proteksi teknologi pada berbagai sektor industri. PT. Nichias Rockwool Indonesia mempunyai beberapa produk utama yang terbagi atas tiga bagian yaitu rockwool, sealing gasket, dan autoparts. Proses produksi yang dilakukan melibatkan mesin-mesin seperti mesin forming, winding, marking dan lain sebagainya. Dalam rangka menaikkan kapasitas produksi, PT. Nichias Rockwool Indonesia menggunakan target waktu penyelesaian suatu produk. Oleh karena itu, dibutuhkan perhitungan waktu baku dalam penyelesaian proses assembling gasket. Waktu baku proses dalam suatu perusahaan memungkinkan periode waktu yang seragam yang digunakan untuk menyelesaikan produksi dalam suatu perusahaan. Pengukuran waktu kerja yang akan dilakukan dalam penelitian ini menggunakan metode jam henti (stopwatch time study). Metode pengukuran ini dilakukan dengan mengukur waktu dengan mengamati dan mencatat waktu operasi kerja. Data waktu ini selanjutnya akan dihitung waktu baku. Jumlah data penelitian sebanyak 150 data yang diambil dari operator terlatih yang dipilih. Faktor penyesuaian dan kelonggaran (allowance) menggunakan metode Westinghouse. Hasil penelitian didapat waktu siklus 21.67 detik, waktu normal 23.62 detik, dan waktu baku 28.34 detik. Kapasitas produksi sebelum adanya waktu baku hanya 553 gasket per hari, setelah dihitungnya waktu baku mengalami peningkatan menjadi 889 gasket per hari atau sebesar 54.97%.
Kata kunci: kapasitas produksi, pengukuran waktu jam henti, waktu bak