Karamanoğlu Mehmetbey University
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A novel dynamic path planning method td learning supported modified spatiotemporal gnn-lstm model on large urban networks
No full textIn this study, a new approach will be discussed in which routing is done by predicting future traffic and the learning algorithm is optimized during navigation. Traffic has a complex structure that is constantly changing. Especially for long-term travel, it is not an optimum approach to suggest a route only by considering the traffic situation at the time the navigation request is made. For this reason, the proposed algorithm recommends a route by taking into account future saturation conditions on the vehicle’s route. Singapore was chosen as the study area. The tests were carried out in a simulation environment. The four selected algorithms were tested spatially and temporally. Especially in long-term travels, the superior success of the proposed method compared to other selected methods has been demonstrated. © The Author(s) 2025
Relationship between epicardial adipose tissue thickness and sedentary time, physical activity level, and physical performance in patients with hypertension
No full textEpicardial adipose tissue is associated with the development of cardiovascular disease and its increase is positively correlated with blood pressure elevation in hypertensive individuals. In the literature, being physically active has been shown to be effective in the treatment of hypertension and reduction of epicardial adipose tissue thickness. The aim of this study was to evaluate the relationship between epicardial adipose tissue thickness and sedentary time, physical activity level and physical performance in patients with hypertension. The physical and demographic characteristics of the 40 patients with hypertension were collected with sociodemographic form. Waist/hip circumference was measured with tape measure and epicardial adipose tissue thickness with echocardiography device. Physical activity levels and sedentary time were recorded via IPAQ-7. Physical performance was determined using the 30-s sit-and-stand test. There was a moderate negative correlation between epicardial adipose tissue thickness and IPAQ-7 score (rho: -0.568 p < 0.001) and a high negative correlation between epicardial adipose tissue thickness and sit-and-stand test score (rho: -0.794 p < 0.001). There was no relationship between epicardial adipose tissue thickness and daily sitting time, BMI, or hip circumference. There was moderate positive correlation between epicardial adipose tissue thickness and age (rho: 0.504 p: 0.001) and low positive correlation between waist circumference (rho: 0.322 p < 0.05).This study demonstrated that the epicardial adipose tissue thickness was negatively associated with activity and performance in hypertensive patients, but not with daily sitting time. These results underscore the importance of physical activity in the management and prevention of chronic diseases
Editöre mektup yanıtı: “Koroner arter kıvrımlılığı ve koroner ateroskleroz yükü”
Full text linkFirst, we would like to thank the author and the editorial team for their attention to and interest in our work. We deeply value your constructive criticism and contributions, which we see as an opportunity for further improvement
3d modelling and x-ray depth analysis map of the pulp with computer software via digital periapical radiography and cone beam computed tomography
No full textObjective: Periapical radiographs (PAR) offer information about the pulp and periodontal health of teeth. However, intraoral radiographs are insufficient for diagnosing buccolingual anomalies and variations such as bifid canals due to their two-dimensional nature. Cone beam computed tomography (CBCT) is the gold standard for 3D imaging in the clinic but requires additional radiation. The aim of this study was to create a software (XPAR) which obtains x-ray depth analysis and 3D modelling of the pulps of single-rooted teeth by converting the grey values in the original radiographs into numerical data. Materials and methods: Two single-rooted teeth were included in the experimental part of the study. Chicken fibula bone was preferred for alveolar bone simulation because it could simulate cortical and trabecular structures due to similarity. A total of four images (60kVp & 70kVp; single alveolar bone & double alveolar bone) were obtained. The aim of this experimental part is to test the repeatability and realism of the algorithm to be created for pulp modelling. Retrospectively, 31 single-rooted teeth with both periapical radiography and cone-beam computed tomography imaging were included in the retrospective part of the study. According to XPAR, depth increase areas were interpreted as root resorption and accessory canal. Depth decrease areas were evaluated as the transformation of the pulp from an elliptical to an oval form, pulp stone, bifid canal formation and the presence of thick alveolar bone. The diagnostic accuracy of XPAR application on pathological and morphological changes was evaluated by comparing the obtained results with CBCT. Results: 80% of the analyses diagnosed as bifurcation by XPAR application were supported by CBCT. This rate decreased to 27% in the diagnosis of transitions from elliptical to oval form. A total of 5 and 19 linear formations observed in the form of depth decrease and increase, respectively, were accepted as image errors in XPAR. Conclusion: Buccolingual bifid canal formations and pulp obliterations can be diagnosed with a rate of nearly 50% with the depth decrease finding obtained in XPAR application. Imaging errors caused by deformed detectors are typically observed as linear formations. © The Author(s) 2025
Physical, nutritional, and bioactive components, in vitro starch digestibility, and textural and organoleptic properties of Beyşehir tarhana with various oleaster parts
No full textBackground and Objective: This study has three main objectives: (1) to analyze the physical and nutritional properties, bioactive component concentrations, and in vitro digestibility of Beyşehir tarhana containing different parts of oleaster; (2) to investigate the effect of incorporating oleaster on textural properties; and (3) to evaluate the influence of the different parts of oleaster on the organoleptic characteristics of Beyşehir tarhana. Findings: The control tarhana showed higher L* and b* values, while tarhana samples with various oleaster parts exhibited the highest a* value (p <.05). Incorporating oleaster components led to significant alterations in protein, ash, fat, dietary fiber, in vitro starch digestibility, total phenolic substance, antioxidant capacity, and the texture and organoleptic properties of Beyşehir tarhana compared to the control (p <.05). Conclusions: The production of Beyşehir tarhana containing different parts of oleaster components led to highly encouraging outcomes, presenting an exciting opportunity for its future production. Significance and Novelty: Beyşehir tarhana differs from traditional tarhana as it undergoes a less extensive fermentation process. It can be consumed as is, or after frying or baking. The addition of different ingredients is crucial due to the limited fermentation and frying processes. © 2024 Cereals & Grains Association.Scientific Research Projects Commission; Bilimsel Araştırma Projeleri Birimi, İstanbul Teknik Üniversitesi, BAP; Karamanoğlu Mehmetbey Üniversitesi, KM
Investigation of piezoelectric and photoluminescence properties of the multifunctional La2Sn2O7 and Ho2Sn2O7 pyrochlore smart materials doped with Eu3+
No full textRE2?xEuxSn2O7 (RE:La3+ and Ho3+, x:0.10) materials were synthesized having both pholuminescence and piezoelectric properties using with solid state reaction method at various reaction temperature and heating duration in open atmosphere. The thermal behaviors, crystal system, surface morphology, EDX analysis, Curie tempereture, photoluminescent properties, dielectric and piezoelectric properties of Eu3+ ions doped La2Sn2O7 and Ho2Sn2O7 were investigated. Both multi-functional smart materials show dielectric, piezoelectric properties and photoluminescence properties which is responsible transitions of doping Eu3+ ions. © 2024 Elsevier B.V.Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, TÜBİTAK, (114Z438
Photoluminescence and thermoluminescence studies of beta-ırradiated ba3cdsi2o8:tb3+ phosphor for led and dosimetry applications
No full textThe present work reports the preparation, characterization, and photoluminescence (PL) and thermoluminescence (TL) responses of Tb3+-doped Ba₃CdSi₂O₈ phosphors. X-ray diffraction analysis confirmed the consistency of the Tb3+-doped Ba₃CdSi₂O₈ samples with the PDF 00-028-0128 card structure. The TL glow curve of the material was examined at different dopant concentrations after irradiation with a 90Sr/90Y beta source. Among the samples, Ba₃CdSi₂O₈: 5% Tb3+ exhibited the highest TL intensity compared with the other concentrations. The glow curve deconvolution method was used to determine the number of peaks, trap structure, and kinetic parameters within the TL glow curve, yielding a figure of merit (FOM) value of 1.11. The PL spectra show that the 2.0%, 3.0%, 4.0%, 5.0%, and 6.0% mole Tb3+-doped Ba₃Cd (SiO₄)₂ phosphors capture excitation energy through the 4f-5d transitions of Tb3+ ions and emit light at 417, 440, 492, 552, 589, and 628 nm, corresponding to the 5D₃–7F₅, 5D₃–7F₄, 5D₄–7F₆, 5D₄–7F₅, 5D₄–7F₄, and 5D₄–7F₃ transitions, respectively. © 2025 The Author(s). Luminescence published by John Wiley & Sons Ltd
Elastic and Acoustic Properties Determination of Epoxy/Polystyrene/Nanoclay/Red Mud Waste Hybrid Composites by Ultrasonic Method
Full text linkUltrasonic methods are more sensitive to defects such as voids, pores, and discontinuities that can diminish the true elastic and acoustic properties of materials compared to destructive testing. Therefore, the elastic properties and some acoustic properties of the epoxy phenol novolac modified with polystyrene (EPN-PS) matrix-based nano- and hybrid composites were determined for the first time using ultrasonic method. Montmorillonite-type nanoclay (NC) and industrial red mud waste (RMW) at a rate of 1-4 and 15-35 wt% respectively, were used as fillers in the composite preparation. According to the results, the highest elastic coefficient values (L = 8.14 GPa, G = 1.76 GPa, K = 5.79 GPa and E = 4.80 GPa) were obtained in the EPN-PS/NC1 (with 1 wt% NC) nanocomposite sample compared to the elastic properties of pure EPN and EPN-PS, while the highest elastic coefficient values (L = 8.97 GPa, G = 2.19 GPa, K = 6.06 GPa, and E = 5.86 GPa) among hybrid composites (HC) were obtained for the HC35 containing 2 wt. % NC and 35 wt% RMW. Due to both its high elastic and good acoustic properties, wall panels and floors produced using HC35 hybrid composite can be used for sound insulation in noisy environments.Highlights First evaluation of the acoustic characteristics of epoxy phenol novolac modified with polystyrene-nanoclay/red mud waste (EPN-PS-NC/RMW) composites. NC4 with 4 wt% nanoclay showed the lowest elastic and acoustic properties. Nanoclay ratio above 1 wt% reduces elastic and acoustic properties. The increasing RMW ratio in hybrid composites increases elastic properties. High elastic and acoustic properties make HC35 ideal for sound insulation.Scientific and Technological Research Council of Turkey (TUBITAK)Open access funding provided by the Scientific and Technological Research Council of Turkey (TUBITAK)
İnvestigation of psychological resilience and care burden of parents caring for children with special healthcare needs in turkey: a cross-sectional study
No full textAim: The study was planned to investigate the resilience and care burden of caregiving parents in Turkey. Methods: Demographic and descriptive characteristics were recorded. Psychological resilience was assessed using the Brief Resilience Scale (BRS) and caregiving burden was assessed using the Zarit Caregiving Burden Scale (ZCBS). Independent Sample t-test and ANOVA Mann-Whitney U and Kruskall Wallis tests were used to analyze the data.Multivariate variance analysis was performed with post-hoc tests to determine the differences between the groups. Significance p < 0.05 was accepted. Results: A total of 112 caregivers, 97 of whom were women, with a mean age of 39.84 ± 10.73 years, participated in the study. The mean age of with children with special healthcare needs was 10.83 ± 8.56 years, 61.6 % were male, and 42.9 % had both physical and mental disabilities. In children with special health needs, 41.1 % had mobility limitations, 43.8 % had communication problems, 44.6 % had learning problems and 31.3 % had nutritional problems. The level of mobility limitation, communication, learning and nutrition problems in children with special healthcare needs and the presence of chronic disease or musculoskeletal system problems in caregivers were found to be associated with care burden (p < 0.05). Psychological resilience of caregivers of those with moderate care burden was lower than those with mild care burden (p < 0.05). There was a negative, moderately significant relationship between caregivers' psychological resilience and care burden (r = −0.356; p < 0.001). Conclusion: New strategies should be developed to increase psychological resilience and reduce the burden of care in caregivers of complex children with special healthcare needs. Implications to practice: The lived experience of caregivers who support children with special healthcare needs can be improved with psychological and practical care support from health professionals. © 2025 Elsevier Inc
Exploring the anticancer potential of dianthus orientalis in pancreatic cancer: a molecular and cellular study
No full textPancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, characterized by limited therapeutic options and poor prognosis. This study investigated the anticancer effects of Dianthus orientalis extracts on pancreatic cancer cell lines (Panc-1 and BxPC-3) with a focus on apoptosis, invasion, and metastasis-related pathways. Chemical analysis using HPLC-MS/MS identified bioactive compounds (vanillic acid, syringic acid, p-coumaric acid, quercetin, hyperoxide) known for their anticancer properties. The Inhibitory Concentration 50 (IC50) value, which is half maximal inhibitory concentration of cancer cells, was determined to be 250 μg/mL at 48 h, and significantly induced apoptosis by decreasing anti-apoptotic gene expressions (Bcl-XL and Bcl-2) and increasing pro-apoptotic gene expressions (Casp3 and Bax) particularly in the Panc-1 cell line. Flow cytometric analysis revealed approximately 55% apoptosis in both cell lines. Molecular docking and dynamics analyses demonstrated strong binding affinities of quercetin and hyperoxide with important cancer-related proteins, including CHEK2 and PALB2. Gene expression analysis demonstrated the upregulation of pro-apoptotic markers like Bax and Casp3, and selective modulation of metastasis-related genes such as SNAI1, PALB2, and CHEK2. The findings highlight the potential of D. orientalis to modulate DNA repair mechanisms and epithelial-mesenchymal transition (EMT) pathways. Furthermore, network pharmacology and in silico tools corroborated its interactions with critical signaling pathways in cancer progression, including PI3K-Akt and MAPK. The study provides the first comprehensive evidence of D. orientalis's antiproliferative through apoptosis induction on pancreatic cancer cell lines, laying the groundwork for future therapeutic applications. © 2025 Elsevier Lt