Karamanoğlu Mehmetbey University
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Evaluation of synthesis variables on the antimicrobial and antioxidant efficacy of silver nanoparticles produced using hibiscus sabdariffa extract
No full textThe increasing interest in biological synthesis techniques can be attributed to the need for non-toxic ways to produce nanoparticles. This study investigated the influence of different parameters on the synthesis of silver nanoparticles (AgNPs) using Hibiscus sabdariffa extract. Several analytical techniques were used to characterize the synthesized AgNPs. Furthermore, the antimicrobial and DPPH radical scavenging activities of the AgNPs were evaluated. XRD analysis validated the synthesis of pure nanosized crystalline silver nanoparticles. At room temperature, as the pH rised during the synthesis, the size of the nanoparticles decreased. Additionally, pH had the biggest impact on the distinctive qualities of AgNPs, while extract concentration, metal salt, and pH all affected the nanoparticles' zeta potential. The synthesized AgNPs showed antibacterial activity against Gram-positive and Gram-negative bacteria, with the greatest activity observed against Staphylococcus aureus. AgNPs have been shown to have greater antibacterial activity when synthesized at a pH of 7.5, as opposed to pH values of 8.5 and 10.5. To sum up, pH played a significant role in the synthesis of AgNPs and was essential for determining the biological activities of the particles. According to this study, it is possible to control nanoparticle synthesis parameters for applications in various industries, such as the food and medical sectors
Nanofiber applications from hijiki macroalgae: Antibacterial and cytotoxicity properties in biocompatible polymers
No full textOne of the current biotechnological applications is nanofiber applications made from algae using the electrospinning technique. Nanofibers containing poly-caprolactone (PCL) extracted from the brown seaweed Hijiki (Sargassum fusiforme) were prepared using electrospinning technique. Water extraction was performed to preserve the integrity of Hijiki components, ensuring their efficacy in subsequent electrospinning and characterization. The morphology and chemical composition of the nanofibers were characterized using field emission scanning electron microscopy (FE-SEM), thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FT-IR) analyses. Hijiki was found to combine well with electrospun biocompatible polymers and effectively provide the common properties of these materials. The cytotoxicity of algae-doped PCL nanofibers was examined in vitro using liver cancer and liver healthy cell lines (HepG2 and The-2). Among hepatic tumor cell lines, the HepG2 cell line has been preferred due to its wide range of scientific applications. Although the nanofibers caused a 28% decrease in liver cancer cell lines viability (HepG2), the decrease in healthy liver cell viability (The-2) was 12%. Algae-doped PCL nanofiber applied to bacteria showed antibacterial effect. Based on the findings, Hijiki macroalgae nanofibers show great promise for tissue regeneration and band-aid applications in the medical industry
Search for fractionally charged particles in proton-proton collisions at (formula presented)
No full textA search is presented for fractionally charged particles with charges below (Formula presented), using their small energy loss in the tracking detector as a key variable to observe a signal. The analyzed dataset corresponds to an integrated luminosity of (Formula presented) of proton-proton collisions collected at (Formula presented) in 2016-2018 at the CERN LHC. This is the first search at the LHC for new particles with a charge between (Formula presented) and (Formula presented), including an extension of previous results at a charge of (Formula presented). Masses up to 640 GeV and charges as low as (Formula presented) are excluded at 95% confidence level. These are the most stringent limits to date for the considered Drell-Yan-like production mode. © 2025 CERN, for the CMS Collaboration
Investigation of piezoelectric and photoluminescence properties of the multifunctional La2Sn2O7 and Ho2Sn2O7 pyrochlore smart materials doped with Eu3+
No full textRE2-xEuxSn2O7 (RE:La3+ and Ho3+, x:0.10) materials were synthesized having both pholuminescence and piezoelectric properties using with solid state reaction method at various reaction temperature and heating duration in open atmosphere. The thermal behaviors, crystal system, surface morphology, EDX analysis, Curie tempereture, photoluminescent properties, dielectric and piezoelectric properties of Eu3+ ions doped La2Sn2O7 and Ho2Sn2O7 were investigated. Both multi-functional smart materials show dielectric, piezoelectric properties and photoluminescence properties which is responsible transitions of doping Eu3+ ions.TUBITAK (The Scientific and Technological Research Council of Turkey) [114Z438]The authors express their gratitude to TUBITAK (The Scientific and Technological Research Council of Turkey) for supporting the project numbered 114Z438. This study was conducted at Karamanoglu Meh-metbey University
Survey of anaplasma spp. in ticks from türkiye: first molecular evidence for a. phagocytophilum-like-1 and 2 strains
No full textIn Türkiye, although there are several studies on Anaplasma spp. in vertebrate host, data on the occurrence of Anaplasma spp. in ticks are still lacking. This study aims to contribute to control strategies by providing new information on the epidemiology of Anaplasma species in Türkiye. A total of 2241 ticks divided into pools in which the presence of A. ovis and A. phagocytophilum was investigated by molecular methods. Maximum likelihood estimate (MLE) per 1000 ticks with 95% confidence intervals (CI) was used to compute infection rates. Overall MLE of infection rate was determined as 34.1 and 3.61 for A. ovis and A. phagocytophilum, respectively. While the infection rate for A. ovis varied from 9.21 (CI 2.81-21.3) in Haemaphysalis parva to 81 (CI 53.8-115) in Dermacentor marginatus, A. phagocytophilum varied from 2.21 (CI 0.11-9.51) in Rhipicephalus bursa to 95.5 (CI 5.61-359) in Hae. concinna. A. phagocytophilum-like-1 and 2 strains in Turkish ticks were originally identified using sequencing and phylogenetic analysis based on the 16S rRNA gene. As a result, A. ovis and A. phagocytophilum could threat animal and human health in the region and strains of A. phagocytophilum should be taken into account when making a differential diagnosis for tick-borne diseases. © 2025, Veteriner Fakultesi Dergisi. All rights reserved
Development of children's perceived nursing image scale: A validity and reliability study
No full textAimProfessional knowledge and awareness of children begins to create at the age of 3-5, and the professional knowledge have acquired at this age was effective in their future career decision-making. This study aimed to develop the Children's Perceived Nursing Image Scale (CPNIS) and evaluate its psychometric properties.MethodsThe methodological study was carried out in a cross-sectional, descriptive, and correlational design. This study was conducted with 614 children aged 8-11 between 21 January-April 2022. The data were collected using a Child Information Form and the CPNIS. The CPNIS is a scale compatible with the deductive approach. The data were analysed using various statistical methods including descriptive statistics (numbers and percentages), t-tests, factor analysis, and correlation analysis. Item-total score analysis, the Intraclass Correlation Coefficient (ICC), and the internal consistency were employed to evaluate the reliability of the measurements. Three-stage cross-sectional study, which followed the STROBE checklist was conducted: (1) development of items, (2) assessing content validity and (3) validity and reliability of the scale.ResultsThe CPNIS is a valid scale consisting of four factors as subdimensions. The total Cronbach's alpha of the scale is 0.93. The scale explained 46.4% of the total variance. The scale Test-Retest analysis, the total ICC value of the scale was found to be 0.84 and p = 0.001.ConclusionEvaluation of the children's perceived nursing image can contribute to the identification of children with negative perceptions in clinics and the planning of interventions that will lead to positive perceptions
The effectiveness of using animal-themed vacutainers to reduce pain and fear in children during bloodletting
No full textIntroduction: This study aimed to compare the effects of vacutainers of three different animal characters on pain and fear in children during bloodletting. Methods: This randomized controlled trial included 180 children between the ages of 4 and 7 years who required bloodletting for routine control. Children were randomized into two groups: experimental and control groups. Routine bloodletting procedure was applied to those in the control group. Animal characters (butterfly, peacock and rabbit) chosen by children in the experimental group was attached to the vacutainer, and then their blood was drawn. The data were obtained by face-to-face interviews with the child, parent and observer before and after the procedure. Children's pain and fear/anxiety levels were evaluated using the Wong-Baker FACES Pain Scale and the Children's Fear Scale, respectively. Results: There was no statistically significant difference between the groups' pre-test scores with respect to age, BMI, gender, fear/anxiety assessments of the child, parent, and observer. Children in the experimental group had significantly lower pain and fear/anxiety levels after the procedure compared to those in the control group(p < 0.000). Conclusions: Animal characters (butterfly, peacock and rabbit) attached to the vacutainer is effective in reducing both fear and pain levels in children during bloodletting.Karamanoglu Mehmetbey University Scientific Research Projects Coordination Unit [05-M-21]We would like to thank the Karamanoglu Mehmetbey University Scientific Research Projects Coordination Unit, which supported the present study under the project numbered 05-M-21
Search for charged-lepton flavor violation in the production and decay of top quarks using trilepton final states in proton-proton collisions at (Formula presented)
Get PDFA search is performed for charged-lepton flavor violating processes in top quark ((Formula presented)) production and decay. The data were collected by the CMS experiment from proton-proton collisions at a center-of-mass energy of 13 TeV and correspond to an integrated luminosity of (Formula presented). The selected events are required to contain one opposite-sign electron-muon pair, a third charged lepton (electron or muon), and at least one jet of which no more than one is associated with a bottom quark. Boosted decision trees are used to distinguish signal from background, exploiting differences in the kinematics of the final states particles. The data are consistent with the standard model expectation. Upper limits at 95% confidence level are placed in the context of effective field theory on the Wilson coefficients, which range between (Formula presented) depending on the flavor of the associated light quark and the Lorentz structure of the interaction. These limits are converted to upper limits on branching fractions involving up (charm) quarks, (Formula presented) ((Formula presented)), of (Formula presented), (Formula presented), and (Formula presented) for tensorlike, vectorlike, and scalarlike interactions, respectively. © 2025 CERN, for the CMS Collaboration
A 3D memristive cubic map with dual discrete memristors: Design, implementation, and application in image encryption
No full textDiscrete chaotic systems based on memristors exhibit excellent dynamical properties and are more straightforward to implement in hardware, making them highly suitable for generating cryptographic keystreams. However, most existing memristor-based chaotic systems rely on a single memristor. This paper introduces a novel discrete chaotic system employing dual memristors, named the 3D memristive cubic map with dual discrete memristors (3D-MCM). The 3D-MCM system demonstrates richer and more intricate dynamical behaviors compared to its single-memristor counterparts, as verified through bifurcation diagrams, Lyapunov exponent spectra, and complexity analyses. Notably, the system exhibits coexisting attractors, substantially enhancing its dynamical complexity. Hardware implementation of the 3D-MCM attractors confirms its feasibility for industrial applications. To illustrate the system's potential in encryption tasks, this study integrates the quaternary-based permutation and dynamic emanating diffusion (QPDED-IE) scheme for image encryption with the 3D-MCM.Experimental results demonstrate that the QPDED-IE scheme based on the 3D-MCM exhibits strong diffusion and confusion properties, effectively resisting cryptanalytic attacks
Comprehensive analysis of elemental and metabolite composition in boraginaceae species from Türkiye
No full textBoraginaceae plants, including four endemic species from T & uuml;rkiye, were analyzed for organic and inorganic compositions using inductively coupled plasma mass spectrometry (ICP-MS) and liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) to explore their nutritional, medicinal, and ecological significance. This study examined 18 species, identifying key elements, such as sodium (87 600.359-118 049.272 g/kg), potassium (98 876.885-145 587.899 g/kg), and iron (70 396.436-116 416.076 g/kg), which showed significant variation. Metabolite profiling revealed the presence of alkaloids, flavonoids, and tannins in most samples. Additionally, 42 amino acids and 35 phenolic compounds were detected, with rosmarinic acid and proline being particularly abundant. Rosmarinic acid was most concentrated in Oi and Ml samples, whereas proline levels ranged from 3023.8086 to 7693.8549 nmol/mL. The study highlights the intricate metabolic and elemental profiles of Boraginaceae species, shedding light on their ecological adaptations and therapeutic potentials. Spearman correlation analysis suggested significant relationships among phenolic compounds, amino acids, and elemental compositions, indicating potential applications in nutrition, pharmacology, and biodiversity conservation