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Data for Dissolution of Cotton by 1-Ethyl-3-Methylimidazolium Acetate Studied with Time-Temperature Superposition for Three Different Fibre Arrangements
No full textThis study has investigated the dissolution of cotton fibres in the ionic liquid 1-ethyl-3-methylimidazolium acetate ([C2mim][OAc]) for three fibre arrangements. Dissolution was carried out with excess [C2mim][OAc] at various temperatures and times followed by coagulation with water. Optical microscopy (OM) indicated that this procedure produced a coagulated fraction surrounding the original fibres. X-ray diffraction (XRD) showed that the crystal structure of this coagulated fraction was predominantly cellulose II, as opposed to the original fibres that were mostly cellulose I. The OM and XRD results showed that growth of the coagulated fraction obeyed time-temperature superposition (TTS) and displayed an Arrhenius behaviour, allowing a dissolution activation energy to be determined. Although the growths of coagulated fraction with time were different for these distinct three arrangements, each could be individually shifted to form master curves using TTS, leading to very similar activation energies, 96 ± 3 kJ/mol
Literature review: methods and validation of facet joints biomechanics in finite element models
No full textAnnotated bibliography supporting a literature review on methodologies for modelling the facet joints in the spin
Public trunk revision 3298 of BISICLES and revision 23085 of Chombo version 3
No full textThis dataset contains archived versions of the model and modelling framework used for the simulations presented in the manuscript "Simulating the Early Holocene demise of the Laurentide Ice Sheet with BISICLES (public trunk revision 3298)". For access to the related manuscript and output data, please refer to the links under 'Related resources' below. Simulating the demise of the Laurentide Ice Sheet covering the Hudson Bay in the early Holocene is important for understanding the role of accelerated changes in ice sheet topography and melt in the '8.2 ka event', a century long cooling of the Northern Hemisphere by several degrees. Freshwater released from the ice sheet through a surface mass balance instability (known as the saddle collapse) has been suggested as a major forcing for the 8.2 ka event, but the temporal evolution of this pulse has not been constrained. Dynamical ice loss and marine interactions could have significantly accelerated the ice sheet demise, but simulating such processes requires computationally expensive models that are difficult to configure and are often impractical for simulating past ice sheets. Here, we developed an ice sheet model setup for studying the Laurentide Ice Sheet's Hudson Bay saddle collapse and the associated meltwater pulse in unprecedented detail using the BISICLES ice sheet model, an efficient marine ice sheet model of the latest generation, capable of refinement to kilometre-scale resolution and higher-order ice flow physics
Dataset associated with "Colliding-wind binary systems: Diffusive shock acceleration and non-thermal emission"
No full textIn the paper we present a model for the particle acceleration at the colliding wind shocks in massive early-type binary systems, and the resulting non-thermal emission. This repository contains the raw data to accompany various figures in this peer-reviewed publication in the Monthly Notices of the Royal Astronomical Society
Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1.
No full textMass spectrometry results for MKS1 pull-downs from mIMCD3 cells across different conditions of ciliogenesis
Dataset associated with "Effect of substrate etching on terahertz metamaterial resonances and its liquid sensing applications"
No full textThe results on the effect of substrate etching on LC resonance of terahertz metamaterials and its liquid sensing applications
Dataset associated with "Nested-Nanobubbles for Ultrasound Triggered Drug Release"
No full textDue to their size (1-10 μm) microbubble-based drug delivery agents suffer from confinement to the vasculature, limiting tumour penetration and potentially reducing drug efficacy. Nanobubbles (NBs) have emerged as promising candidates for ultrasound triggered drug delivery, due to their small size allowing drug delivery complexes to take advantage of the enhanced permeability and retention effect. In this study we describe a simple method for production of Nested-NBs, by encapsulation of nanobubbles (~ 100 nm) within drug loaded liposomes. This method combines the efficient and well-established drug loading capabilities of liposomes, whilst utilising NBs as an acoustic trigger for drug release. Encapsulation was characterised using Transmission Electron Microscopy with encapsulation efficiency of 22 ± 2 %. Nested-NBs demonstrated echogenicity using diagnostic B-mode imaging and acoustic emissions were monitored during high intensity focused ultrasound (HIFU) in addition to monitoring of model drug release. Results showed that although the encapsulated NBs were destroyed by pulsed HIFU (peak negative pressure 1.54 – 4.83 MPa), signified by loss of echogenicity and detection of inertial cavitation, no model drug release was observed. Changing modality to continuous wave (CW) HIFU produced release across a range of peak negative pressures (2.01 – 3.90 MPa), likely due to a synergistic effect of mechanical and increased thermal stimuli. Due to this, we predict that our NBs contain a mixed population of both gaseous and liquid core particles, which upon CW HIFU undergo rapid phase conversion, triggering liposomal drug release. This hypothesis was investigated using previously described models to predict the existence of droplets and their phase change potential and the ability of this phase change to induce liposomal drug release
EMBER comparison - systematic review
No full textShortlisted papers considered as part of a systematic review of moorland burning literature, with codings for seven ecosystem properties relevant to the EMBER research project. Soil temperature disturbances, water table depths, FPOM concentrations, invertebrates, water temperature
Kiel Uprising: Women's activism and the German Revolution November 1918 - Teaching
Get PDFThis pack of teaching materials was created as part of the project “Kiel Uprising: Women's Activism and the German Revolution November 1918” funded by the Arts and Humanities Research Council. It uses questions and ideas generated by the travelling exhibition “Women of Aktion”. It is recommended that the panels for this exhibition, available to download as a PDF, are displayed
DNA Nanostructure - Nanopipette biosensing
Get PDFThe dataset provided here contains the relevant data for the Nature communications paper titled "Rational design of DNA nanostructures for single molecule biosensing" by Raveendran et al. The raw ion current data obtained for all the experiments reported in the paper is provided in abf file format. The dataset also includes DNA origami design as cadnano files and lists of oligo in excel sheets. A separate excel file with the source data for the figures presented in the paper is also provided. See the 'readme' file for detailed description