1401 research outputs found
Sort by
Aminooxy-BCN glycoconjugates
Get PDFNMR spectroscopy data for aminooxybicyclononyne derivatives and glycan conjugates and protein mass spectrometry data for protein ligation reaction
The impact of semi-natural woodland and pasture on soil properties and streamflow - dataset.
No full textData from streamflow and soil investigations at RSPB Haweswater, Lake District, UK. Data consists of streamflow, rainfall and soil properties; soil moisture, topsoil permeability, subsoil permeability and bulk density. Data collected in 2018-2020
Protein-conjugated microbubbles for the selective targeting of S. aureus biofilms - dataset
No full textMolecular dynamics simulations reveal membrane lipid interactions of the full-length lymphocyte specific kinase Lck: dataset
No full textThe membrane-bound lymphocyte-specific protein-tyrosine kinase (Lck) triggers T cell antigen receptor signalling to initiate adaptive immune responses. Despite many structure-function studies, the mode of action of Lck and the potential role of plasma membrane lipids in regulating Lck’s activity remains elusive. Advances in molecular dynamics simulations of membrane proteins in complex lipid bilayers have opened a new perspective in gathering such information. Here, we have modelled the full-length Lck open and closed conformations available from crystallographic studies and simulated its interaction with the inner leaflet of the T cell plasma membrane. In both conformations, we found that the unstructured unique domain and the structured domains including the kinase interacted with the membrane with a preference for PIP lipids. Interestingly, our simulations suggest that the Lck-SH2 domain interacts with lipids differently in the open and closed Lck conformations, demonstrating that lipid interaction can potentially regulate Lck’s conformation and in turn modulate T cell signalling. Additionally, the Lck-SH2 and kinase domain residues that significantly contacted PIP lipids are found to be conserved among the Src family of kinases, thereby potentially representing similar PIP interactions within the family
Crystallisation, Dissolution and Saturation Temperatures Data for a Model Fuel in Presence of a Cold-Flow Improver
No full textCrystallisation and solubility data are provided for a model fuel in the absense and presense of a flow improving additiv
Thin film epitaxial [111] Co50Pt50: Structure, magnetisation, and spin polarisation
No full textElectrical transport, x-ray, magnetometry associated with the publication "Thin film epitaxial [111] Co50Pt50: Structure, magnetisation, and spin polarisation
Dataset for "Positively Charged Additives Facilitate Incorporation in Inorganic Single Crystals"
Get PDFIncorporation of guest additives within inorganic single crystals offers a unique strategy for creating nanocomposites with tailored properties. This dataset contains microscopy, XRD, Raman, and zeta potential data supporting a study of the incorporation of nanoparticles within a range of inorganic crystals. Cationic additives are used to synthesize nanocomposites, delivering exceptional levels of incorporation of up to 70 wt% of positively charged amino acids, polymer particles, gold nanoparticles, and silver nanoclusters within inorganic single crystals. This high additive loading endows the nanocomposites with new functional properties including plasmon coupling, bright fluorescence, and surface-enhanced Raman scattering (SERS)
Calculation data sheets for the rebound case study examples used in the journal working paper "Advancing the necessary foundations for empirical energy rebound estimates: A partial equilibrium analysis framework"
No full textDataset associated with Effects of Structural Ordering on IR Active Vibrations Within Bi₂(Te₍₁₋ₓ₎Seₓ)₃
No full textThis is the dataset associated with the materials study performed on the IR active E1u phonon within the Bi₂(Te₍₁₋ₓ₎Seₓ)₃ alloy system. It contains THz and DC conductivity data that show the change in phonon dynamics over a wide range of temperatures and stoichiometries
Data for "Mechanistic Study of the Conductance and Enhanced Single-Molecule Detection in a Polymer Electrolyte Nanopore"
Get PDFThe data set contains all relevant ionic current traces and voltammetric data recorded using pClamp system for the associated paper entitled: 'Mechanistic Study of the Conductance and Enhanced Single-Molecule Detection in a Polymer Electrolyte Nanopore'. The data is in the native pClamp format of abf files. Analysis routine can be performed with script that relies on abf files. The data set is aim to allow users to re-analysis the data and to reproduce the observations made in the associated publication