1401 research outputs found
Sort by
Gallium exchange in Fe-PQS complexes
No full textDFT structures from Gallium-For Iron substitutions within PQS complexes. Raw NMR data for all PQS, Fe-PQS and Ga-PQS complexe
Research Data: Achieving Emission Reductions without Furthering Social Inequality
No full textThese data show consumption-based greenhouse gas (GHG) emissions of UK households from 2001-2020. As demographic variables, income decile and age group are attached. Emissions are shown in two different ways. First, emissions are shown for each year individually. Second, emissions are shown as a 2007 equivalent. These second data show the emissions that consumption from the different years would have caused assuming the economic structure and emission coefficients from 2007. Data are reported as a carbon equivalent, meaning that all GHGs are converted into their carbon equivalent. The GHGs included are carbon dioxide, methane, nitrous oxide, hydrofluorocarbons, perfluorocarbons, sulphur hexafluoride and nitrogen trifluoride
Short survey on aspirin use for cancer prevention among the UK general public
Get PDFAustralian guidance recommends aspirin for colorectal cancer prevention among people aged 50-70 at population risk. The medication could be offered more widely in the future in the UK and other countries. We conducted an online survey to investigate aspirin use, and awareness of aspirin for cancer prevention among the UK general population. We recruited 400 UK respondents aged 50-70 through a market research company to an online survey
Dataset for "Cement and concrete decarbonisation roadmaps - a meta-analysis within the context of the United Kingdom"
Get PDFThis Supplementary Information file provides full details of the methods used for the analysis presented in the article Marsh A.T.M. et al. “Cement and concrete decarbonisation roadmaps – a meta-analysis within the context of the United Kingdom”.
The sections describe the methods used for:
S1. Assigning material scope to decarbonisation strategies
S2. Determining material scope of the roadmaps
S3. Determining existence of trends between strategies and actor type
S4. Determining Technology and Market Readiness Level (TMRL) range for each strategy
S5. Determining carbon reduction potential for each strateg
Removal of cesium and strontium ions with enhanced solid-liquid separation by combined ion exchange and BaSO4 co-precipitation.
No full textThis is the abstract dataset for the manuscript that is under the revision and will be published soon
Substitution of Met-38 to Ile in gamma-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid
No full textα-, β-, and γ-Synuclein are intrinsically disordered proteins implicated in physiological processes in the nervous system of vertebrates. α-synuclein (αSyn) is the amyloidogenic protein associated with Parkinson’s disease and certain other neurodegenerative disorders. Intensive research has focused on the mechanisms that cause αSyn to form amyloid structures, identifying its NAC region as being necessary and sufficient for amyloid assembly. Recent work has shown that a 7-residue sequence (P1) is necessary for αSyn amyloid formation. Although γ-synuclein (γSyn) is 55% identical in sequence to αSyn and its pathological deposits are also observed in association with neurodegenerative conditions, γSyn is resilient to amyloid formation in vitro. Here, we report a rare single nucleotide polymorphism (SNP) in the SNCG gene encoding γSyn, found in two patients with amyotrophic lateral sclerosis (ALS). The SNP results in the substitution of Met38 with Ile in the P1 region of the protein. These individuals also had a second, common and nonpathological, SNP in SNCG resulting in the substitution of Glu110 with Val. In vitro studies demonstrate that the Ile38 variant accelerates amyloid fibril assembly. Contrastingly, Val110 retards fibril assembly and mitigates the effect of Ile38. Substitution of residue 38 with Leu had little effect, while Val retards, and Ala increases the rate of amyloid formation. Ile38 γSyn also results in the formation of γSyn-containing inclusions in cells. The results show how a single point substitution can enhance amyloid formation of γSyn and highlight the P1 region in driving amyloid formation in another synuclein family member
Data associated with 'Free-Standing Hierarchically Porous Silica Nanoparticle Superstructures: Bridging the Nano- to Microscale for Tailorable Delivery of Small and Large Therapeutics'
No full textRaw data for all figures in the associated paper 'Free-Standing Hierarchically Porous Silica Nanoparticle Superstructures: Bridging the Nano- to Microscale for Tailorable Delivery of Small and Large Therapeutics
Data relating to "The importance of acid processed meteoric smoke relative to meteoric fragments for crystal nucleation in polar stratospheric clouds"
No full textThis study demonstrates that modelling of crystal nucleation in PSCs and resulting ozone depletion relies on accurate understanding of the transport and chemical processing of MSPs. This will affect estimated sensitivity of stratospheric chemistry to rare events such as large volcanic eruptions and long-term forecasting of ozone recovery in a changing climate
Meniscus sensitivity to knee contact mechanics - computational data
No full textThe data comprises Finite Element model input files for Abaqus 2019 representative of 1 generic tibifemoral condyle and 3 image-specific tibiofemoral joints.
Each of the baseline datasets was extracted from data shared under CC-BY license:
- generic model from the open-knee project first generation (https://doi.org/10.18735/b0zv-n395) as used in Meng Q., Fisher J. & Wilcox R.K. (2017). The effects of geometric uncertainties on computational modelling of knee biomechanics. R. Soc. Open Sci. 4, 170670
- specimen-specific model from the IMBE knee dataset: Cooper R.J., Day G.A., Wijayathunga V.N., Yao J., Mengoni M., Wilcox R.K. & Jones A.C. (2023) Three subject-specific human tibiofemoral joint finite element models: complete three-dimensional imaging (CT & MR), experimental validation and modelling dataset. https://doi.org/10.5518/981
Derived models were generated from the input files to create a total of 40 model instances used in a sensitivity study. The datasets contains derived input files and python scripts to generate the derived models.
The dataset also contains Finite Element outputs of interest for each of the 40 models
STrain Analysis and Mapping of the Plantar Surface (STAMPS) – A novel technique of plantar load analysis during gait - Dataset.
No full textThis data set contains the collated regional strain and peak plantar pressure (PPP) data for the plantar aspect of the foot for participants 1-3 from the journal article "STrain Analysis and Mapping of the Plantar Surface (STAMPS) - A novel technique of plantar load analysis during gait"