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Capturing the Impact of Protein Unfolding on the Dynamic Assembly of Protein Networks. [Dataset].
No full textThe rapid assembly of molecular or nanoscale building blocks into extended arrays is crucial to the construction of functional networks in vivo and in vitro, depending on various factors. One factor seldom considered is the dynamic changes of the building block shape. Folded protein building blocks offer a unique system to investigate dynamic shape changes due to their intrinsic ability to change from a compact and specific folded structure to an extended unfolded structure in response to a perturbation such as force. Here, we use photochemically cross-linked folded protein hydrogels constructed from force labile protein building blocks as a model dynamic shape-changing network system and characterise them by combining time-resolved rheology and small-angle x-ray scattering (SAXS). This approach probes both the load-bearing network structures, using rheology, and network architectures, using SAXS, thereby providing a cross-length scale understanding of the network formation. We propose a triple assembly model for the structural evolution of networks constructed from force labile protein building block consisting of: primary formation where monomeric folded proteins create the preliminary protein network scaffold; a subsequent secondary formation phase, where larger oligomers of protein diffuse to join the preliminary network scaffold; and finally in situ unfolding and relaxation which leads to the mature network structure of connected larger and denser fractal-like clusters. The time-resolved SAXS data provides evidence that protein unfolding occurs on the edges of the fractal-like clusters, resulting in a population of unfolded proteins in the inter-cluster space between clusters. Identifying the key stages of assembly in protein networks constructed from force labile proteins provides a greater understanding of the importance of protein unfolding in hierarchical biomechanics in vivo and creates future opportunities to develop bespoke biomaterials for novel biomedical applications
River Augmented Global Landslide Dams (RAGLAD)
No full textTo address the current data and understanding knowledge gap in landslide dam inventories related to geomorphological parameters, a new global-scale landslide dam dataset named River Augmented Global Landslide Dams (RAGLAD) was created. RAGLAD is a collection of landslide dam records from multiple data sources published in various languages and many of these records we have been able to precisely geolocate. In total, 779 landslide dam records were compiled from 34 countries/regions. The spatial distribution, time trend, triggers, and geomorphological characteristic of the landslides and catchments where landslide dams formed are summarized. The relationships between geomorphological characteristics for landslides that form river dams are discussed and compared with those of landslides more generally. Additionally, a potential threshold for landslide dam formation is proposed, based on the relationship of landslide volume to river width. Our findings from our analysis of the value of the use of additional fluvial datasets to augment the database parameters indicate that they can be applied as a reliable supplemental data source, when the landslide dam records were accurately and precisely geolocated, although location precision in smaller river catchment areas can result in some uncertainty at this scale. This newly collected and supplemented dataset will allow the analysis and development of new relationships between landslides located near rivers and their actual propensity to block those particular rivers based on their geomorphology
Data Associated with the Paper 'Data-Driven CFD-Based Design Optimisation of Flow Pattern in a Gravitational Mixer Settler'
No full textData generated of the various fluid flow simulations undertaken
in the set of DoE to allow the data-driven CFD-based optimisation investigatio
IHAT Surface Modelling
No full textThese data are the .cif files for the fully optimized structures of adipate and tartrate adsorptions on ferrihydrite surfaces. The ‘wet’ surfaces have an explicit layer of water, and the ‘dry’ surfaces are without water. Prot, SemiProt and Unprot denote the protonation state of the ligand (i.e. fully protonated, semi-protonated or completely deprotonated)
The Universality of Hair as a Nucleant: Exploring the Effects of Surface Chemistry and Topography
Get PDFThis dataset contains the raw and meta data for the publication: Universality of Hair as a Nucleant: Exploring the Effects of Surface Chemistry and Topography.
This includes atomic force microscopy, x-ray photoelectron spectroscopy, and scanning ion conductance microscopy data for the characterisation of hair samples that were used in crystallization experiments to study the effect of topography, surface charge, and surface chemistry on the nucleating ability of different hair types. A simulation model was developed for the quantitative interpretation of scanning ion conductance microscopy data, which has been included as a COMSOL report that includes all the information on the simulations. The scanning electron microscopy images were used to visualize the distribution of CaCO3 crystals grown on different hair surfaces. The metadata for finding the activity of hairs are categorized, where it was recorded whether or not nucleation occurred during contact. In situ synchrotron WAXS analysis of KNO3 crystallization was carried out in levitated droplets to learn why the formation of α-KNO3 was suppressed in our silicon oil-bound droplet-based experiment
Interviews with the Registrar Staff of the Royal Armouries: November 2021 to February 2023
No full textThis dataset consists of thirteen transcripts from a series of semi-structured interviews conducted between November 2021 and February 2023 for the collaborative PhD project 'How do ethics influence the development of policies for accessing public collections which are essentially restricted by law? A case study of the Royal Armouries'. Conducted with five members of the Royal Armouries' collections department, these conversations sought to reveal the intricacies of the routine management of museum weapons collections and the central role of museum registrars in providing access to these heavily restricted objects. These conversations were structured around four major themes - legislation, governance, ethics, and access - examining their complex interplay in the everyday pursuit of responsible weapons stewardship by a national museum
Experimental Thermal State QKD Dataset
No full textAmplitude measurements used for the plots of graphs in Figures 4, 5, 7, 8, and C1 of the associated paper "Quantum key distribution with displaced thermal states", generated through radio broadcasts. This set aims to allow recreation of those graphs, and confirmation of the claims made concerning those specific examples. Contained are the results of two uses of a thermal state QKD protocol, one performed with wired broadcasts, and one performed wirelessly. Both of these attempts produce a set of amplitudes measurements for Alice, Bob, and Eve. These results demonstrate that thermal broadcasts provide correlated amplitude measurements when split by a power splitter, which can then be used to produce bit strings for key distribution
Data associated with "On-axis Sputtering Fabrication of Tm3Fe5O12 Film with Perpendicular Magnetic Anisotropy"
No full textDataset for 'Hybrid organic-inorganic blast furnace slag binders activated with alkali acetates'
No full textRaw data for all figures in the associated paper 'Hybrid Organic–Inorganic Blast Furnace Slag Binders Activated with Alkali Acetates