Open Journal Systems of Universitas Muhammadiyah Palangkaraya
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Hubungan Karakteristik Pasien Skizofrenia dengan Efek Samping Neurolectic Malignant Syndrome (NMS): The Relationship Between the Characteristics of Schizophrenia Patients with Neuroleptic Malignant Syndrome (NMS)
No full textTerapi antipsikotik yang menjadi salah satu penyebab terjadinya neuroleptic malignant syndrome (NMS) merupakan terapi utama pasien skizofrenia dan digunakan dalam terapi jangka panjang. Peningkatan kasus skizofrenia yang berhubungan dengan peningkatan penggunaan antipsikotik dan karakteristik yang berbeda pada tiap individu berisiko meningkatkan efek samping NMS hingga mortalitas. Penelitian ini bertujuan melihat hubungan antara karakteristik pasien skizofrenia dengan efek samping neuroleptic malignant syndrome (NMS). Penelitian dilakukan di RSJ Prof. dr. Soerojo Magelang dan RSJ Dr. Radjiman Wediodiningrat Lawang dengan rancangan observasional analitik case control secara retrospektif melalui data rekam medis pasien rawat inap periode Januari 2018 - Agustus 2023. Populasi penelitian terdiri dari 31 subyek untuk kelompok kasus (pasien skizofrenia yang mengalami NMS) dan 62 subyek untuk kelompok kontrol (pasien skizofrenia tidak mengalami NMS). Hasil analisis bivariat secara chi square dan fisher test tidak menunjukkan nilai yang signifikan antara hubungan karakteristik pasien (umur, jenis kelamin, obat lain, penyakit penyerta, jumlah antipsikotik dan dosis antipsikotik) skizofrenia dengan efek samping neuroleptic malignant syndrome (NMS). Penelitian ini menyimpulkan tidak terdapat hubungan antara karakteristik pasien skizofrenia dengan efek samping neuroleptic malignant syndrome (NMS)
Combined Effects of Curcuma xanthorrhiza Rhizome and Persea americana Leaves Extracts on Streptozotocin-Induced Diabetes in Rats
No full textIndonesia's rich biodiversity encompasses numerous plants with ethnomedicinal applications, including avocado (Persea americana) leaves and temulawak (Curcuma xanthorrhiza) rhizomes, traditionally used for managing diabetes mellitus. This study investigated the antidiabetic activity of a combination of C. xanthorrhiza rhizomes and P. americana leaves in streptozotocin (STZ)-induced diabetic rats. Extracts were obtained via 72-hour maceration using 96% ethanol, followed by phytochemical screening and a 3-day toxicity assessment in rats at doses of 50, 150, and 200 mg/kg BW. Diabetic rats, induced with a single intraperitoneal injection of 20 mg/kg STZ, were treated for 14 days with three different combination formulas of C. xanthorrhiza rhizome and P. americana leaf extracts: Formula 1 (0.6 g : 0.4 g), Formula 2 (0.4 g : 0.6 g), and Formula 3 (0.4 g : 0.4 g). Metformin (500 mg/kg/day) served as the positive control, and 0.5% CMC-Na was the negative control. Phytochemical analysis revealed the presence of various bioactive compounds in both extracts. No significant toxicity was observed in rats across the tested doses. The Mann-Whitney test indicated a significant difference in blood glucose levels in diabetic rats after 14 days of treatment (p=0.037). Notably, all combination formulas exhibited antidiabetic activity. Specifically, Formula 1 demonstrated comparable antidiabetic efficacy to metformin (500 mg/kg). These findings suggest that combining C. xanthorrhiza and P. americana extracts possesses significant antidiabetic potential
Analisis Jalur Pengaruh Faktor Prediktor Terhadap Length Of Stay (LOS) Pasien Diabetes Melitus Tipe II pada Instalasi Rawat Inap Rumah Sakit Umum Daerah Ruteng
No full textLatar Belakang: Dari survei awal diketahui rata-rata LOS pasien DM tipe 2 di RSUD Ruteng pada tahun 2023 adalah ≤ 5 hari. Jika dibandingkan dengan standar, rata-rata LOS pasien DM tipe II di RSUD Ruteng masih masuk dalam kategori lama perawatan. Faktor yang mempengaruhi Length Of Stay (LOS) pasien adalah status gizi (diukur dengan IMT), Kadar Gula Darah Sewaktu (KGDS), dan Usia. Penelitian ini bertujuan untuk mengetahui pengaruh Usia dan IMT terhadap KGDS serta dampaknya terhadap LOS pasien DM tipe II di RSUD Ruteng tahun 2023.
Metode: Penelitian ini merupakan penelitian cross-sectional untuk menganalisis hubungan langsung dan tidak langsung antara faktor prediktor dengan LOS menggunakan analisis jalur. Data diperoleh dari rekam medis pasien dengan jumlah populasi sebanyak 260 dokumen. Teknik pengambilan sampelnya adalah simple random sampling, dan dari perhitungan diperoleh 111 sampel.
Hasil: Terdapat pengaruh tidak langsung yang signifikan IMT terhadap LOS melalui KGDS (z Sobel = 2.64, p=0.008), KGDS berpengaruh signifikan terhadap LOS (t=9.82, p=0.000), IMT berpengaruh signifikan terhadap KGDS (t=4.46, p= 0.001), dan tidak terdapat pengaruh tidak langsung yang signifikan usia terhadap LOS melalui KGDS (z Sobel = 0.82, p=0.40).
Simpulan: KGDS berhasil memediasi pengaruh IMT terhadap LOS sehingga menghasilkan IMT berpengaruh signifikan terhadap LOS melalui RBS. Sebaliknya RBS tidak berhasil memediasi pengaruh Age terhadap LOS sehingga mengakibatkan Age tidak berpengaruh signifikan terhadap LOS melalui RBS
Hubungan Antara Status Gizi dengan Kejadian Hipertensi pada Lansia di RSD Kota Tidore Kepulauan
No full textLatar belakang: Hipertensi adalah kondisi peningkatan tekanan darah yang dapat mengganggu pasokan oksigen dan nutrisi ke jaringan tubuh. Prevalensinya meningkat seiring bertambahnya usia, dengan lansia menjadi kelompok yang paling berisiko. Faktor-faktor seperti usia, jenis kelamin, pola makan, merokok, dan obesitas berperan dalam terjadinya hipertensi. Indeks massa tubuh (IMT) sering digunakan untuk menilai status gizi dan berhubungan erat dengan risiko hipertensi. Tujuan: Penelitian ini bertujuan untuk mengetahui prevalensi hipertensi pada lansia di RSD kota Tidore Kepulauan, untuk mengetahui status gizi pada lansia di RSD kota Tidore Kepulauan, serta untuk mengetahui hubungan status gizi dengan kejadian hipertensi pada lansia di RSD kota Tidore Kepulauan. Metode: Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross-sectional. Penelitian ini menggunakan data rekam medis. Hasil: Penelitian ini menunjukkan bahwa dari 91 sampel didapatkan prevalensi hipertensi pada lansia lebih banyak pada perempuan, yaitu 69,2%. Kelompok usia terbanyak adalah lanjut usia (elderly) yaitu 70,3%. Status gizi terbanyak adalah obesitas yaitu 52,7%. Jenis hipertensi terbanyak adalah hipertensi tingkat 1 yaitu 64,8%. Hasil analisis dengan chi square menyatakan terdapat hubungan yang signifikan antara status gizi dengan kejadian hipertensi pada lansia (p = 0,023). Kesimpulan: Berdasarkan jenis kelamin, prevalensi hipertensi pada lansia didapatkan lebih banyak pada perempuan dibandingkan dengan laki-laki. Berdasarkan status gizi, didapatkan indeks massa tubuh berlebih dan obesitas lebih banyak pada lansia dibandingkan dengan indeks massa tubuh normal dan kurang. Terdapat hubungan antara status gizi dengan kejadian hipertensi pada lansia di RSD Kota Tidore Kepulauan
Perbandingan Ph Urine pada Pasien Batu Saluran Kemih dengan dan Tanpa Diabetes Melitus Tipe 2 di Rumah Sakit Ibnu Sina Tahun 2022-2024
No full textPenyakit batu saluran kemih (BSK) merupakan masalah kesehatan yang terus meningkat dan sering dikaitkan dengan berbagai faktor metabolik, termasuk diabetes melitus (DM) tipe 2. Pasien dengan DM memiliki risiko lebih tinggi mengalami urolitiasis, terutama batu asam urat, akibat pH urine yang lebih rendah. Penelitian ini bertujuan untuk membandingkan pH urine pada pasien batu saluran kemih dengan dan tanpa diabetes melitus tipe 2 di Rumah Sakit Ibnu Sina pada tahun 2022–2024. Metode penelitian yang digunakan adalah penelitian observasional analitik dengan desain studi kasus-kontrol. Penelitian ini melibatkan 50 pasien batu saluran kemih, yang terdiri atas 25 pasien dengan DM tipe 2 dan 25 pasien tanpa DM tipe 2. Hasil penelitian menunjukkan bahwa sebagian besar pasien batu saluran kemih di Rumah Sakit Ibnu Sina pada tahun 2022–2024 adalah laki-laki, yaitu sebanyak 31 orang (62%), dengan kelompok usia terbanyak berada dalam rentang 46–55 tahun (36%). Pasien batu saluran kemih tanpa DM tipe 2 cenderung memiliki pH urine basa (>5,5) sebesar 64%, sedangkan pasien dengan DM tipe 2 cenderung memiliki pH urine asam (≤5,5) sebesar 60%. Hasil uji mann-whitney menunjukkan adanya perbedaan yang signifikan dengan nilai p = 0,048 (p < 0,05). Kesimpulan dari penelitian ini adalah bahwa pasien dengan DM tipe 2 memiliki pH urine yang lebih asam, yang dapat meningkatkan risiko pembentukan batu saluran kemi
Learning Methods for Children with Dyslexia
No full textBackground: Reading is an ability that every human being must possess. We will always encounter writings that require reading and comprehension skills. Still, dyslexic children have difficulty in Reading, which causes dyslexic children to experience a decline in academics and can potentially experience unpleasant behavioral problems from their environment, where children can be ignored by their friends, even to the point of becoming victims of bullying so that several methods need to be applied to help them. This study aimed to determine the various methods that can be applied to help dyslexic children. The research method used is a literature study that presents a complete survey by summarizing, describing, and combining relevant research, packaged using a narrative review. Four methods can be identified based on the journals collected: the Orton-Gilingham method, Treatment of spelling, Reading and writing skills, Learning to read without spelling (BMTM), and the Reading aloud method. The results of this study are expected to help teachers provide learning methods to dyslexic children
Pengembangan Sistem Pemesanan Tiket Bus Online Berbasis Web dan Mobile Pada PO. Logos: Development of an Online Bus Ticket Reservation System Based on Web and Mobile for PO. Logos
No full textThe development of information and computer technology has simplified various aspects of life, including transportation, particularly in the area of bus ticket reservations. The manual ticket reservation system still in use has several drawbacks, such as low efficiency, the risk of running out of tickets, and data entry errors. This study aims to design and develop a web and mobile-based bus ticket reservation information system for PT. Po. Logos. By using the waterfall method, this system is expected to improve operational efficiency and customer service. The system developed utilizes PHP programming language and MySQL database to manage ticket data, schedules, and reservations in real-time. Through user-friendly interface design and secure transaction processes, the system aims to address the issues present in the manual reservation system. This research also contributes to the advancement of technology in the transportation sector and opens up further opportunities for innovation in digital-based transportation services
GERHANA DALAM NALAR TARJIH MUHAMMADIYAH : ANTARA SAINS DAN TRADISI MASYARAKAT
No full textThis article discusses the perspective of the Muhammadiyah Tarjih Council on the eclipse phenomenon, by placing it in an integrative framework between modern science and community traditions. In Muhammadiyah's view, an eclipse is not a bad omen as some traditional communities believe, but a natural event that can be explained scientifically as part of Allah's law (sunnatullah). Nevertheless, Muhammadiyah still emphasizes the importance of the spiritual dimension through the eclipse prayer as a form of cosmic awareness and human submission to God. With a normative legal approach, this article also explores how Muhammadiyah's tarjih approach seeks to enlighten the community through da'wah that is educative, rational, and remains sensitive to local culture. Using a qualitative-descriptive approach and normative analysis, this paper concludes that the eclipse in the view of tarjih Muhammadiyah is a meeting point between faith, science, and tradition, which represents a progressive style of Islam
Pengaruh Waktu Penundaan terhadap Hasil Pemeriksaan Bilirubin Total dengan Metode Diazo Sulfanilat: The Effect of Delay Time on Total Bilirubin Examination Results Using the Diazo Sulfanilate Method
No full textExamination of total bilirubin is one of the laboratory tests to determine the function of the liver and bile ducts, as well as impaired liver function. A delay in total bilirubin examination can affect the results of the examination. According to Good Laboratory Practice, total bilirubin activity should be checked as soon as possible. The purpose of this study was to determine the difference in the results of the examination of total serum bilirubin, which was examined immediately with a delay of 3 days and a delay of 5 days, which was stored at 2-8 oC. The delay in total bilirubin examination with serum samples will be stable if stored at 2-8 oC for 5-7 days. This type of research uses experimental research, the sampling technique used in this study is random sampling, involving as many as 15 samples from students of the Muhammadiyah University of Palangkaraya. Examination of total bilirubin was carried out using the Diazo Sulfanilate method with a Photometer Biosystem 350. The results of the average total bilirubin levels were immediately examined, with a delay of 3 days and a delay of 5 days, namely 0.53, 0.55, and 0.67 (mg/dL, respectively). ). This shows that the longer the delay in total bilirubin examination, the higher the total bilirubin value. Based on the One Way Anova test, the p value = 0.439 showed that there was no significant difference or no effect of time delay on the results of the examination of total bilirubin levels, which were examined immediately, with a delay of 3 days, and a delay of 5 days
Marketing Politik Calon Gubernur Kalimantan Tengah 2024: Analisis Konten Instagram: Political Marketing of Central Kalimantan Governor Candidate 2024: Instagram Content Analysis
No full textThis research was carried out to analyze the political marketing of the 2024 Central Kalimantan governor candidates, namely Willy Midel Yoseph, Nadalsyah Koyem, Agustiar Sabran, and Abdul Razak on Instagram social media. This research uses political marketing strategy theory which includes push, pull, and pass marketing which is applied to social media (Computer Mediated Communication) which consists of Selective Self-Presentation, Verbal clues or text messages, and Many-to-many communication. Data was obtained by conducting content analysis on Instagram social media accounts. The results of the research show that the four candidates for governor of Central Kalimantan in 2024 have delivered repeated messages on social media using informative and educative methods. In general, the political communication marketing strategy implemented is quite optimal because every candidate's post implements it, as seen on Push Marketing, First Candidate Willy Midel Yoseph created promotional content, Second Candidate Nadalsyah Koyem created collaborative content with Influencers, Third Candidate Agustiar Sabran created visual campaign content, and Fourth Candidate Abdul Razak created social activity content. At Pull Marketing, the four candidates uttered slogans explaining their vision and mission work programs, the first candidate, namely Tuh Iye Kalteng Harmonis, the second candidate, namely Kalteng Hebat, the third candidate, namely Kalteng Berkah Kalteng Maju, and the fourth candidate, is Kalteng Amanah. At Marketing Pass, the first candidate was promoted by the public, the second candidate was promoted by influencers, the third candidate was promoted by political figures, and the fourth candidate was promoted by community figures