4075 research outputs found
Sort by
Pengetahuan dan Sikap Ibu Hamil terhadap Swamedikasi: Analisis Faktor Demografi dan Riwayat Penyakit Kronis
Full text linkSwamedikasi pada wanita hamil memerlukan kehati-hatian karena dapat menimbulkan risiko bagi ibu maupun janin, sehingga pengetahuan dan sikap yang tepat sangat penting untuk memastikan keamanan penggunaan obat selama kehamilan. Penelitian bertujuan untuk mengetahui tingkat pengetahuan dan sikap wanita hamil terhadap swamedikasi di Kota Yogyakarta, serta faktor karakteristik yang berhubungan dengan keduanya. Desain penelitian dengan potong lintang pada 150 wanita hamil, menggunakan teknik accidental sampling. Pengambilan data menggunakan kuesioner terstruktur yang telah tervalidasi, dilakukan di RSKIA PKU Muhammadiyah Kotagede dan Klinik Puri Adisty Yogyakarta pada Maret–Mei 2024. Uji statistik menggunakan rank spearman (usia, usia kehamilan, pendidikan, pendapatan, dan jarak faskes) dan chi square (pekerjaan, riwayat penyakit kronis, jumlah kehamilan). Hasil menunjukkan mayoritas responden berusia 20–30 tahun (56%), trimester III kehamilan (53,33%), primigravida (54,67%), berpendidikan terakhir SMA/ sederajat (57,33%), tidak bekerja (64,67%), pendapatan keluarga >Rp3.000.000 (60%), jarak rumah ke faskes >2 km (54,67%), dan tidak memiliki penyakit kronis (77,33%). Responden memiliki tingkat pengetahuan tinggi (62,03%) dan sikap positif (84,81%) terhadap swamedikasi. Dapat disimpulkan bahwa wanita hamil di Kota Yogyakarta memiliki pengetahuan tinggi dan sikap positif terhadap swamedikasi, tidak ditemukan demografi yang berkorelasi dengan pengetahuan, namun sikap responden terbukti dipengaruhi secara signifikan oleh tingkat pendidikan (p=0,032) dan riwayat penyakit kronis (p=0,002).
Self-medication during pregnancy requires caution due to potential risks to both the mother and fetus; therefore, appropriate knowledge and attitudes are crucial to ensure medication safety. This study aims to determine the level of knowledge and attitudes of pregnant women toward self-medication in Yogyakarta City, as well as to analyze the characteristic factors associated with them. This was a cross-sectional study involving 150 pregnant women selected using accidental sampling. Data collection was conducted using a validated structured questionnaire at RSKIA PKU Muhammadiyah Kotagede and Puri Adisty Clinic Yogyakarta from March to May 2024. Statistical analysis was performed using the Spearman Rank test (for age, gestational age, education, income, and distance to health facilities) and the Chi-Square test (for occupation, history of chronic disease, and number of pregnancies). The results showed that the majority of respondents were aged 20–30 years (56%), in the third trimester of pregnancy (53.33%), primigravida (54.67%), had a high school education or equivalent (57.33%), were unemployed (64.67%), had a family income >IDR 3,000,000 (60%), lived >2 km from health facilities (54.67%), and had no history of chronic disease (77.33%). Respondents demonstrated a high level of knowledge (62.03%) and a positive attitude (84.81%) toward self-medication. It can be concluded that pregnant women in Yogyakarta City possess high knowledge and positive attitudes toward self-medication. Although no demographic characteristics were found to correlate with knowledge, respondents attitudes were significantly influenced by education level (p=0.032) and history of chronic disease (p=0.002)
Optimasi Kombinasi Polimer Hidroksi Propil Metil Selulosa K4M dan Natrium Karboksimetil Selulosa pada Formula Patch Ekstrak Daun Alpukat (Persea americana Mill.) dengan Metode Simplex Lattice Design
Full text linkEkstrak etanol daun alpukat (Persea americana Mill.) telah terbukti memiliki kemampuan menghambat pertumbuhan bakteri karena memiliki kandungan senyawa berupa saponin, alkaloid, flavonoid, dan tanin. Untuk meningkatkan kenyamanan dalam penggunaannya, ekstrak diformulasikan dalam bentuk patch. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh kombinasi antara polimer hidroksi propil metil selulosa (HPMC) K4M serta natrium karboksi metil selulosa (CMC-Na) terhadap karakteristik fisik patch ekstrak daun alpukat. Penelitian diawali dengan skrining fitokimia ekstrak daun alpukat berupa uji alkaloid, flavonoid, saponin, dan tanin. Optimasi formula patch dilakukan dengan variasi konsentrasi HPMC K4M dan CMC-Na pada konsentrasi 0–3% dengan metode Simplex Lattice Design (SLD) menggunakan software Design Expert 13. Kemudian dilakukan uji sifat fisik meliputi uji organoleptis, bobot, pH, ketebalan, ketahanan lipat, dan swelling index, untuk menentukan formula terbaik. Verifikasi dilakukan dengan membandingkan hasil uji sifat fisik prediksi software dengan hasil pengujian di laboratorium menggunakan one sample t-test dengan taraf kepercayaan 95%. Penelitian ini menunjukkan bahwa formula optimum yaitu dengan perbandingan HPMC K4M sebesar 2,325% dan CMC-Na sebesar 0,675%. Kombinasi polimer HPMC K4M dan CMC-Na secara signifikan dapat mempengaruhi ketahanan lipat, ketebalan, pH, dan bobot; namun tidak menunjukkan pengaruh yang signifikan terhadap nilai swelling index patch ekstrak daun alpukat. Hasil verifikasi formula optimum menunjukkan tidak ada perbedaan signifikan antara nilai prediksi program dengan hasil percobaan (sig 2-tailed > 0,05), sehingga menunjukkan bahwa model prediksi efektif dalam menghasilkan formula yang dapat memberikan sifat fisik patch sesuai yang diinginkan.
Avocado leaf extract (Persea americana Mill.) has been proven to have the ability to inhibit bacterial growth because of the active compounds such as saponins, alkaloids, flavonoids, and tannins. To improve comfort in its use, the extract was formulated in the form of a patch. The focus of this study was to assess how the combination of hydroxy propyl methyl cellulose (HPMC) K4M polymers and sodium carboxy methyl cellulose (CMC-Na) affects the characteristics of the physical properties of patches made from avocado leaf extract. The study began with phytochemical screening of avocado leaf extract in the form of alkaloid, flavonoid, saponin, and tannin tests. Patch formula optimization was carried out by varying the concentration of HPMC K4M and CMC-Na (0–3%) using the Simplex Lattice Design method in Design Expert 13 software. The patch preparation was tested for physical properties including organoleptic tests, weight, pH, thickness, folding resistance, and swelling index, to determine the best formula. After that, verification was carried out by comparing the results of the software predicted physical properties test with the results of laboratory tests using a one sample t-test with a 95% confidence level. This study showed that the optimum formula was with a comparative concentration of HPMC K4M of 2.325% and CMC-Na of 0.675%. The combination of HPMC K4M and CMC-Na polymers was found to have significantly affected the folding resistance, thickness, pH, and weight, but did not show a significant effect on their swelling index value of avocado leaf extract patches. The results of the optimum formula verification showed no significant difference between the program predicted values and the experimental results (sig 2-tailed > 0.05), thus indicating that the prediction model was effective in producing a formula that could provide the desired physical properties of the patch
Efektivitas Sari Katuk dan Tomat terhadap Berat Badan dan Persen Lemak Tubuh Siswi Overweight
Full text linkAbstract—Overweight is a condition of excessive fat accumulation that results in excess body weight, which can affect health. Overweight in adolescents is a major health problem in society in both developed and developing countries. The prevalence of overweight in East Java reached 11.3%, higher than the national data of 8%. The effects of overweight include obesity, chronic diseases, type 2 diabetes mellitus, and others. This research method uses a quasi-experimental design with a pretest-posttest approach with a control group design, which is divided into three groups: the control group, treatment group 1 (P1), and treatment group 2 (P2). The sampling technique used was total sampling with 30 samples. Body weight was measured before and after treatment in all groups. The treatment groups received 150 ml of Katuk and tomato juice in ratios P1 (0.5:0.75) and P2 (1:1.5) for 14 days. The statistical test results showed that the body weight of the treatment group (P1 = 0.019) and (P2 = 0.000), while the body fat percentage (P1 = 0.005) and (P2 = 0.000), which means there is an effect. Giving katuk and tomato leaf juice effectively reduces body weight and fat percentage. Treatment group 2 (P2) as the most effective dose in reducing body weight and body fat percentage in overweight students at MAN 1 Banyuwangi.
Keywords: overweight, katuk leaves, tomato
Abstrak—Overweight merupakan kondisi penimbunan lemak berlebih yang menyebabkan kelebihan berat badan yang menganggu kesehatan. Overweight pada remaja menjadi permasalahan kesehatan yang besar di masyarakat baik di negara maju maupun negara berkembang. Prevalensi kejadian overweight di Jawa Timur mencapai 11,3% lebih tinggi daripada data nasional sebesar 8%. Dampak overweight yaitu menyebabkan obesitas, penyakit kronis, diabetes melitus tipe 2, dan lain-lain. Metode penelitian ini menggunakan quasi experiment dengan pretest-posttest with control group design yang terbagi menjadi tiga kelompok, yaitu kelompok kontrol, kelompok perlakuan 1 (P1) dan kelompok perlakuan 2 (P2). Teknik pengambilan sampel menggunakan teknik total sampling dengan 30 sampel. Semua kelompok diukur berat badan dan persen lemak tubuh sebelum dan setelah diberi perlakuan. Kelompok perlakuan diberikan 150 ml sari katuk dan tomat dengan ratio P1 (0,5:0,75) sedangkan P2 (1:1,5) selama 14 hari. Hasil uji statistik diketahui berat badan kelompok perlakuan (P1 = 0,019) dan (P2 = 0,000) sedangkan persen lemak tubuh (P1 = 0,005) dan (P2 = 0,000) yang berarti terdapat pengaruh. Pemberian sari katuk dan tomat efektif dalam menurunkan berat badan dan persen lemak tubuh. Kelompok perlakuan 2 (P2) menjadi dosis paling efektif dalam menurunkan berat badan dan persen lemak tubuh pada siswi overweight di MAN 1 Banyuwangi.
Kata kunci: overweight, katuk, toma
The Isoflavone Contents of Devon 1 Soybeans during Fermentation and Processing into Soybean-Tempeh Steamed Buns
Full text linkAbstract—The soybean Devon 1 variety is a superior variety developed in Indonesia. The isoflavone content makes this soybean a top choice for a functional food. However, fermenting soybeans into tempeh and processing them into other products can affect the final isoflavone content. The objective of this study was to analyze the total isoflavone and its derivatives content in Devon 1 soybeans, soybean tempeh, soybean tempeh flour, and buns made from tempeh flour. The content of each isoflavone type was determined by high-performance liquid chromatography at λ249 and λ260 nm wavelengths. The buns were made from tempeh flour with variations of tempeh flour substitution of 0, 10, 20, and 30%. The results showed that the fermentation of Devon 1 soybeans and further processing of tempeh significantly altered the isoflavone components and content. The concentrations of daidzin and genistin in tempeh were decreased, while daidzein and genistein were increased. Further processing of tempeh into flour increased all isoflavone levels significantly, which might be caused by the isoflavone transformation during drying and enzymatic activity. Substitution of wheat flour with soybean tempeh flour increased these four isoflavones content of the buns. Therefore, tempeh flour made from Devon 1 soybeans has the potential to be used as a functional food ingredient rich in bioactive compounds that promote health.
Keywords: flour, heat, isoflavone aglycones, isoflavone glycoside, soybean tempeh
Abstrak—Kedelai varietas Devon 1 merupakan varietas unggul yang dikembangkan di Indonesia. Kandungan isoflavonnya menjadikan kedelai ini sebagai pilihan utama untuk pembuatan pangan fungsional. Namun, proses fermentasi kedelai menjadi tempe, serta pengolahan lebih lanjut menjadi berbagai produk turunan dapat memengaruhi kandungan akhir isoflavonnya. Penelitian ini bertujuan untuk menganalisa kandungan total isoflavon dan turunannya pada kedelai Devon 1, tempe kedelai, tepung tempe kedelai, serta bakpao yang dibuat dari tepung tempe. Kandungan masing-masing jenis isoflavon diuji menggunakan kromatografi cair kinerja tinggi pada panjang gelombang λ249 dan λ260 nm. Adapun bakpao dibuat dari tepung tempe dengan variasi substitusi tepung tempe sebesar 0, 10, 20, dan 30%. Hasil penelitian ini menunjukkan bahwa fermentasi kedelai Devon 1 dan pengolahan tempe lebih lanjut secara signifikan mengubah komponen dan kandungan isoflavon. Kandungan daidzin dan genistin dalam tempe menurun, sedangkan kandungan daidzein dan genisteinnya mengalami peningkatan. Pengolahan tempe menjadi tepung lebih lanjut meningkatkan seluruh kandungan isoflavon secara signifikan, yang kemungkinan disebabkan oleh transformasi isoflavon selama proses pengeringan dan aktivitas enzimatis. Substitusi tepung terigu dengan tepung tempe meningkatkan kandungan keempat jenis isoflavon pada bakpao. Dengan demikian, tepung tempe kedelai Devon 1 berpotensi digunakan sebagai bahan pangan fungsional yang kaya akan senyawa bioaktif untuk menunjang kesehatan.
Kata kunci: aglikon isoflavon, glikosida isoflavon, pemanasan, tempe kedelai, tepung
 
A Social Emotional Game untuk Meningkatkan Self-Esteem
No full textGame dengan elemen dramatis dapat menjadi media efektif untuk meningkatkan self-esteem pada remaja. Penelitian ini menganalisis tiga game independen (Omori, Hibernation Day, dan A Space for the Unbound) untuk mengidentifikasi bagaimana elemen-elemen dramatis dalam game tersebut mendukung perkembangan sosial-emosional pemain. Hasil penelitian ini diharapkan dapat memberikan wawasan baru bagi desainer game dalam menciptakan pengalaman bermain yang tidak hanya menghibur, tetapi juga bermanfaat bagi kesehatan mental pemain
Strategies for Empowering Small and Medium Enterprises to Promote Sustainable Tourism in Tourist Villages: A Systematic Literature Review
Full text linkMicro, Small, and Medium Enterprises (MSMEs) are crucial drivers of sustainable tourism in rural communities, yet their potential is often constrained by structural challenges. This systematic literature review, conducted using the PRISMA protocol covering publications from 2020 to 2025, analyzes empowerment strategies for MSMEs in tourism villages, focusing on Indonesia and the Philippines. The findings reveal that leadership, digital innovation, and capacity development are essential for strengthening economic resilience, environmental preservation, and cultural conservation. Successful cases, such as Ponggok Village (Indonesia) demonstrate how an integrated approach—combining stakeholder collaboration, technology, and training—can enhance operational efficiency and expand market access. However, barriers such as uneven infrastructure, low digital literacy, and dependence on external funding persist, necessitating local policy interventions. This study underscores the need for inclusive governance models that prioritize marginalized groups (e.g., women and rural entrepreneurs) and align with the UN Sustainable Development Goals (SDGs 8, 9, and 11). The limitations of this research include its geographical focus on Southeast Asia and the predominance of short-term case studies. Future research should explore long-term impacts and develop measurable frameworks applicable to diverse socio-economic contexts. This paper contributes to the discourse on inclusive tourism development by providing actionable insights for policymakers, practitioners, and academics to leverage MSMEs as catalysts for sustainable rural transformation
Pengaruh ownership structure terhadap earnings management
Full text linkPurpose – This study investigates the impact of state ownership, institutional ownership, and managerial ownership on accrual and real earnings management in non-financial sector companies listed on the Indonesia Stock Exchange (IDX) during 2020 and 2021.
Methods – The research utilizes a sample of 1,327 firm-year observations, comprising 904 companies for accrual earnings management analysis and 423 companies for real earnings management analysis. Established models are employed to measure earnings management.
Findings – The results indicate that state ownership does not significantly affect either accrual or real earnings management. Institutional ownership has a significant positive effect on accrual earnings management but no significant impact on real earnings management. Meanwhile, managerial ownership has no significant effect on accrual earnings management but exerts a significant negative influence on real earnings management.
Implications - These findings provide insights for regulators, investors, and corporate governance stakeholders regarding the role of ownership structure in earnings management practices. Policymakers may consider these results when designing regulations to enhance financial reporting transparency.
Originality – This study contributes to the literature by examining the distinct effects of different ownership structures on both accrual and real earnings management within the Indonesian market, offering empirical evidence from a recent dataset
The Control problem discovery formula: Practical framework in MCS for research and business
No full textPurpose – This study develops a conceptual framework as a formula to systematically discover control problems within organizations by integrating organizational objectives, nature, and existing management control systems (MCS), so facilitating the solution process for research and business.
Methods – This qualitative research uses six undergraduate students’ theses on MCS from diverse organizational contexts. It is based on information analysis from collected documentation through interviews, observations, and document analysis, completed with a triangulation method to minimize bias. Then, we do synthesis and exploration to construct an effective framework for discovering control problems.
Findings – The study highlights that control problems often arise from misaligned objectives, organizational and cultural complexities, and deficiencies in MCS design and implementation. The proposed framework, as a formula, can connect organizational goals, nature, and MCS through iterative feedback loops, enabling organizations to discover root problems effectively and facilitate the solution development process.
Implications – Practically, this framework provides an approach as a systematic formula and implemented in a structured way to help managers, researchers, and businessmen discover organizations’ control problems effectively.
Originality – This research fills gaps in the MCS literature by offering a practical formula with mechanisms to demonstrate and explain the linkages between the symptoms of control problems and their root causes
Strategi keuangan, corporate governance, dan nilai perusahaan: Peran mediasi profitabilitas
Full text linkPurpose - This research examines the influence of Financial Strategy (Working Capital and Capital Structure) and Corporate Governance on Firm Value, with profitability as an intervening variable.
Method - The research was conducted on companies listed in the Kompas 100 Index on the Indonesia Stock Exchange during 2021-2022. Samples were selected using purposive sampling and analyzed using path analysis.
Findings - The Results reveal significant positive effects of Working Capital Management, Capital Structure, and Corporate Governance on Profitability. This underscores the potential of a well-crafted financial strategy to enhance profitability. Conversely, working capital management and corporate governance significantly negatively impact Firm Value, while Capital Structure and Profitability demonstrate significant positive influences. Profitability effectively mediates the relationship between Working Capital, Capital Structure, Corporate Governance, and Firm Value.
Implications - These findings have significant practical implications. They serve as a valuable reference for management, providing insights on how to optimize financial decisions and governance to maximize firm value. For investors, this research offers important indicators for evaluating investment prospects, empowering them to make informed decisions
Hubungan Karakteristik Pasien Hipertensi dengan Kepatuhan Minum Obat di UPT Puskesmas Kemirimuka
Full text linkAbstract—Adherence is often a problem for patients suffering from chronic diseases requiring long-term treatment. The target set by the Depok City Health Office for hypertensive patients undergoing treatment has not yet reached 100%, with only 23% of hypertensive patients receiving treatment at Puskesmas Kemiri Muka. This study aims to determine the relationship between patient characteristics and medication adherence behavior among hypertensive patients at UPT Puskesmas Kemiri Muka, Depok City, in 2024. This is a quantitative study with an analytical design using a cross-sectional approach. Data collection was conducted in May 2024. The study population consists of all hypertensive patients seeking treatment at Puskesmas Kemiri Muka. A total of 85 patients were selected as samples using purposive sampling. The research instrument was a questionnaire containing a set of questions that respondents had to answer. The data analysis used was univariate and bivariate analysis with the Chi-Square statistical test. The study results indicate a significant relationship between knowledge and medication adherence (p-value = 0.00). However, employment status and education level were not significantly associated with medication adherence (p-value ≥ 0.05). Based on these findings, it is recommended that the health center provide leaflets or posters related to medication adherence in the patient waiting area, which could help improve patient knowledge and awareness regarding the importance of consistent medication intake.
Keywords: adherence, hypertension, behavior, knowladge, patient characteristics
Abstrak—Kepatuhan sering menjadi masalah pada pasien yang menderita penyakit kronik dengan pengobatan jangka panjang. Diketahui sasaran dari Dinas Kesehatan Kota Depok untuk pasien hipertensi yang melakukan pengobatan belum mencapai 100 %, dimana hanya sebesar (23%) pasien hipertensi yang melakukan pengobatan di Puskesmas Kemiri Muka. Tujuan penelitian ini adalah untuk mengetahui hubungan karakteristik pasien dengan perilaku kepatuhan minum obat pada penderita hipertensi di UPT Puskesmas Kemiri Muka Kota Depok tahun 2024. Penelitian ini merupakan penelitian kuantitatif dengan desain analitik melalui pendekatan Cross Sectional. Pengambilan data dilakukan pada Bulan Mei 2024. Populasi penelitian ini adalah seluruh pasien hipertensi yang berobat di Puskesmas Kemirimuka. Jumlah sampel yang di ambil sebanyak 85 pasien dengan teknik purposive sampling. Instrumen yang digunakan dalam penelitian ini berupa kuesioner yang berisi sejumlah pertanyaan yang harus dijawab oleh responden. Analisis data yang digunakan ialah univariat dan bivariate dengan uji statistic Chi Square. Hasil pada penelitian ini menunjukkan terdapat hubungan antara pengetahuan dengan kepatuhan minum obat (pvalue = 0,00). Sedangkan variabel status pekerjaan dan tingkat pendidikan tidak berhubungan dengan kepatuhan minum obat (pvalue ≥ 0,05). Bedasarkan hasil penelitian, maka saran yang diberikan yaitu pihak puskesmas dapat menyediakan leaflet atau poster yang berkenaan dengan kepatuhan minum obat di ruang tunggu pasien, sehingga dapat memberikan pengetahuan pasien yang membacanya.
Kata kunci: kepatuhan, hipertensi, perilaku , pengetahuan, karakteristik pasie