Jurnal Fakultas Farmasi Umi (Universitas Muslim Indonesia)
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PENETAPAN KADAR FENOLIK TOTAL DARI EKSTRAK ETANOL BUNGA ROSELLA BERWARNA MERAH (Hibiscus sabdariffa L.) DENGAN MENGGUNAKAN SPEKTROFOTOMETRI UV-Vis
Get PDFEssential ingredients comfounds in roselle (Hibiscus sabdariffa L.) petals is anthocyanin pigments which include flavonoid that acts as an antioxidant. The aim of this research is to determine content of total phenolic of red roselle flowers (Hibiscus sabdariffa L.) ethanol extract. Sample as many one kilograms extracted by maceration method using ethanol 96%. Resulty 127,03 grams extract. Total phenolic content determined by UV-Vis spectrophotometer at wavelenght 737 nm with gallic acid equivalent as standard reference with Folin-Ciocalteau reagent. The result show the rendamen of ethanolic extract is 12.703% with total phenolic content is 0.1853%
PENGEMBANGAN FORMULASI MIKROEMULSI MINYAK SEREH (Cymbopogon nardus) MENGGUNAKAN EMULGATOR SURFAKTAN NONIONIK
Get PDFCitronella oil (Cymbopogon nardus) is an essential oil which useful as an antibacterial that is usuallyprovided in the form of macroemulsion for topical use. absorption of macroemulsion through the skin relatively low, thermodynamically is not stable and can produce a separate phase in the storage period. The one of development emulsion system to get better characteristics is to form a microemulsion. Microemulsion is an oil and water dispersion stable thermodynamically stabilized by surfactants and in some cases a cosurfactant. The objective of this study was to formulatecitronella oil in the form of a stable microemulsion using nonionic surfactant. Optimization of the type and amount of emulsifier (surfactant) was required to formulate a stable microemulsion. In this study, microemulsion was evaluated during a month. Type and concentration of surfactant, cosurfactant, Citronella oil (Cymbopogon nardus) and water was optimized. A stable citronella oil microemulsion was successfully created with composition of 15% PEG 400 as cosurfactant, 15% tween 80 as surfactant, 2-4% Citronella oil as oil phase and 10% glycerin as humectant and distilled water as aqueous phase. From the observation, microemulsion formula has clear appearance but physically unstable during a month storag
ANALISIS AKTIVITAS ANTIOKSIDAN PRODUK SIRUP BUAH MENGKUDU (Morinda citrifolia L.) DENGAN METODE DPPH
Get PDFThis research is about antioxidant activity analysis of Noni products syrup (Morinda citrifolia L.) using DPPH (1,1-diphenyl-2-picrylhydrazil) method. The research aimed to analysis of antioxidant activity of two different brands of Noni products syrup using spectrophotometer UV-Vis. This analysis using quarcetin as standard to determine antioxidant activity and DPPH reagen as radical sources. Quarcetin and Noni products syrup are made five series concentrations in metanol. One ml of each concentration added 4 ml DPPH 50 µM and then added metanol up to 10 ml in flask. Then incubated for 30 minutes at room temperature and protected from light. Measurement of absorbance using spectrophotometer UV-Vis at 514 nm. The IC50 values were 25.7 µg/mL for brand A, and 9.839 µg/mL for brand B
UJI EFEK HIPOGLIKEMIK KOMBINASI EKSTRAK ETANOL DAUN SAMBILOTO (Andrographis paniculata Nees) dengan AKARBOSE pada TIKUS PUTIH (Rattus norvegicus) TERINDUKSI ALOKSAN
Get PDFAcarbose and sambiloto have the same mechanism of action in lowering blood glucose levels by inhibiting alfaglukosidase enzymes in the gut. This study aims to determine the hypoglycemic effect and combination effect from ethanol extract of sambiloto leaves (Andrographis paniculata Nees) with acarbose in rat (Rattus norvegicus) induced alloxan. Twelve Wistar rats were divided into 4 groups; negative control, positive control, and two treatment groups (EEDS 59 mg/kgBW with Acarbose 2,05 mg/kgBB as combination I and EEDS 234 mg/kgBW with Acarbose 2,05 mg/kgBB as combination II). Diabetes Mellitus was induced by Aloksan Monohidrate dose 135 mg/kg BB for three days. Level of blood glucose was measured with glukometer at 2, 4, 6 and 8 day. Treatment with combinations of EEDS doses 59 and 234 mg/kgBW and Acarbose 2,05 mg/kgBB for 7 days significantly decreased blood glucose level (p<0,05) by 48,97 %, and 58,81 % respectively
UJI TOKSISITAS EKSTRAK DAUN PLETEKAN (Ruellia tuberosa L.) DENGAN MENGGUNAKAN METODE BRINE SHRIMP LETHALITY TEST (BSLT)
Get PDFMinnie root (Ruellia tuberosa L.) belongs to Acanthaceae family. In traditional medicine has been used as diuretic, antidiabetic, antipyretic and antihypertensive and it also recently been incorporated as a component in a herbal tea in Taiwan. This research is aim to determine LC50 value of Minnie root leaves extract (Ruellia tuberosa L.) to Artemia salina Leach shrimp larvae. Dryed samples extracted by graduate maceration with n-hexan, ethyl acetate and ethanol respectively. Rendamen n-hexane extract obtained as much as 1.158%, ethyl acetate extract as much as 2.017% and ethanol extract as much as 3.669 %. Based on qualitative screening used TLC method, ethyl acetate extracts and ethanol extracts of Minnie root (Ruellia tuberosa L.) leaves contain alkaloid, saponin, flavonoid and phenolic compounds. Toxicity assay Artemia salina Leach shrimp larvae have been conducted on leaves extracts of Minnie root (Ruellia tuberosa L.). Toxicity assay on sample extract of Minnie root (Ruellia tuberosa L.) leaves determine by counting the number died of larvae after 24 hours treatment. LC50 on sample calculated by probit analysis method. The toxicity assay showed LC50 of ethyl acetate extracts and ethanol extracts are toxic with LC50 266.07 ± 0.93 µg/mL and 142.160 ± 1.30 µg/mL
IDENTIFIKASI FLAVONOID DAUN TEH HIJAU (Camelia sinensis L. Kuntze) SECARA REAKSI WARNA DAN KROMATOGRAFI LAPIS TIPIS
Get PDFGreen tea plant (Camellia sinensis L. Kuntze) were examined in this study were taken from green tea products Cap Head Djenggot, from the area of Solo, Central Java. This plant thrives in the area of Green Tea plantation in the Solo area. For identification of the content of flavonoids in green tea leaves can be done Thin Layer Chromatography is accompanied by a color reaction.Spotting obtained detected with ammonia vapor is then observed with UV light UV 254 nm and 366 nm. In observation using a 254 nm UV light there is a blackish brown spots on the fraction of water-chloroform, the chloroform fraction of the spots are a light green color, and the n-butanol fraction contained a brown patches muda.Dengan using 366 nm UV rays are one dark brown spots on the fraction of water-chloroform, the chloroform fraction contained patches of light green color, and the n-butanol fraction contained a light brown spots.Based on data obtained from the reaction of color and Thin Layer Chromatography showed that the compound contained flavonoids in green tea leaves
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN TALAS KETAN (Colocasia esculenta) TERHADAP BAKTERI Saphylococcus aureus DAN Salmonella thypi SECARA DIFUSI AGAR
Get PDFAntibacterial activity of taro leaves ekxtract has been conducted. The Recearch aimed to determine the antibacterial activity and concentration of ethanol extract of taro leaves (Colocacia esculeta) inhibited the growth of either Salmonella thypi and Staphylococcus aureus by agar diffusion. The result of the antibacterial activity screening in concentration of 1% showed that the ethanol extract of taro leaves by solid dilution provided activity againts Salmonella thypii and Staphylococcus aureus. Based on the test results of antibacterial activity by agar diffusion using concentration of 1% , 2% and 4 % showed that the ethanol extract of taro has the largest inhibition zone diameter againts Staphylococcus aureus of 4% was 15 mm
ISOLASI KITOSAN DARI LIMBAH CANGKANG KEPITING BAKAU (Scylla serrata) DAN APLIKASINYA TERHADAP PENYERAPAN TRIGLISERIDA
Get PDFChitosan is the result of deacetylation process from chitin which it can be found on Crustacean outer shell such as crabs. Chitosan can bind fat if it was consumed by human. The fat-binding ability of chitosan depends on the deacetylation degree. The research have been made into two phases. The first phase, chitosan was made from crab shell using NaOH. The deacetylation degree from chitosan that was made from the earlier process was analyzed with FTIR. The deacetylation degree result of the research was 59.39% using NaOH 50%. The second phase was the process of adsorbing triglycerides using chitosan in 10, 30, 45, and 60 minutes which was analyzed using spectrophotometer UV-Vis. The result of this research showed that the optimum triglycerides with 0.5, 1, 3 gram of chitosan was 2.99%, 3.14%, and 3.36%
PENGUKURAN AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN KELOR (Moringa oleifera Lam.) MENGGUNAKAN METODE FRAP (Ferric Reducing Antioxidant Power)
Get PDFMeasurement of antioxidant activity of ethanol extract of Marunggai leaves (Moringa oleifera Lam) was conducted. The aim research to obtain antioxidant activity using FRAP (Ferric Reducing Antioxidant Power). Marunggai leaves (Moringa oleifera Lam.) ware extracted using maceration method by ethanol 96 %. Free radical activity absorbance was measured with a spectrophotometer at a wavelength of 720 nm and the total value of antioxidant activity was calculated based on the data absorbance. The calculations showed that Marunggai leaves (Moringa oleifera Lam.) have the antioxidant activity with the value 7,923 mg AAE/g extract
STANDARISASI VITAMIN C PADA BUAH BENGKUANG (Pachyrhizus erosus) SECARA SPEKTROFOTOMETRI UV-VIS
Get PDFHave been conducted by a obstetrical research of vitamin C at juicy tuber by spectrophotometry UV – Vis. The research aim to determine and compare the content of vitamin C from juicy tuber. Firstly fruit of juicy tuberare cleared by their seed then it weighed after that it enhanced by oxilate acid 0.4% and than it blended and filtered. Filtrat obtained to qualitative analyze by using the react specific and standarization of vitamin C using the spectrophotometry UV – Visible at wave legth 516 nm obtained rate of mean vitamin C that is juicy tuber yaitu 91.97 mg/100g