South Eastern European Journal of Public Health (SEEJPH - Universität Bielefeld)
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Role of training on counseling skills during Internship- A prototype study on Preoperative counselling skills
Full text linkBackground: Interns frequently exhibit inadequate preoperative counseling skills, adversely impacting patient care and satisfaction. Objective: This study aims to conduct a comparative analysis of communication skills between trained and untrained medical interns in preoperative counseling for major elective surgeries. Methods: A prospective interventional study was conducted involving 100 interns from the 2024-25 batch at Burdwan Medical College, randomized into Group T (trained, n=50) and Group U (untrained, n=50). Group T received a two-hour training session comprising a one-hour classroom lecture with audiovisual materials and a one-hour group discussion and role-play. Both groups were assessed through Objective Structured Clinical Examination (OSCE) stations involving standardized patients and relatives. Performance was evaluated using a pre-validated five-point scale by independent observers. Data were analyzed using independent sample t-tests and Chi-Square tests, with significance set at p<0.05. Results: Trained interns (Group T) demonstrated significantly superior communication skills compared to untrained interns (Group U). The mean performance score for Group T was 4.06 (SD=0.93) versus 2.78 (SD=1.23) for Group U (p<0.001). Specifically, in addressing key counseling questions, 80% of Group T correctly addressed Q1 compared to 52% of Group U (p=0.003). For Q2, 84% of Group T versus 54% of Group U answered correctly (p=0.001); Q3 saw 78% versus 54% (p=0.011); Q4, 72% versus 48% (p=0.014); and Q5, 92% of Group T compared to 72% of Group U (p=0.009). These findings indicate a substantial enhancement in the ability of trained interns to effectively communicate preoperative information. Conclusion: A concise, two-hour training intervention significantly enhances medical interns\u27 preoperative counseling skills, advocating for its integration into the Competency-Based Medical Education (CBME) curriculum
NEUROPROTECTIVE EFFECT OF LINALOOL IN CHRONIC UNPREDICTABLE STRESS-INDUCED COGNITIVE IMPAIRMENT - IN SILICO AND IN VIVO STUDIES
Full text linkThe growing prevalence of stress-induced cognitive impairment is becoming a significant concern, although the precise mechanism is still not fully understood. The chronic unpredictable stress (CUS) model is widely used to study stress-induced cognitive impairment, as it correlates with cognitive decline, behavioral changes, and abnormal cortisol levels in humans. Linalool, known for its traditional use in alleviating anxiety, acting as an antidepressant, sedative, and neuroprotective agent, was investigated in this study. The research explored the genes involved in stress-induced cognitive impairment through network pharmacology, molecular docking, and in vivo methods to assess linalool\u27s neuroprotective effects. The study identified PTGS2, GSK3B, MAPK1, JAK2, PARP1, KDR, NR3C1, MDM2, PRKCA, and MAPK8 as key targets for therapeutic activity in CUS and a strong docking score with PTGS2. The network analysis revealed that neuroprotective effects of linalool have been associated with its modulation of neurodegeneration and sphingolipid signaling pathways, indicating that linalool may inhibit these pathways. The in vivo findings showed that Linalool ameliorated the chronic stress induced behavioral changes, reduced the acetylcholinesterase levels in the brain and corticosterone levels in blood. Both in vitro and in vivo studies indicate that linalool possesses neuroprotective properties and could be a potential target for treating cognitive impairment
Digitalization in dental implants
Full text linkThis article examines the transformative impact of digitalization on implant dentistry, with a particular focus on technological advancements that have significantly enhanced patient outcomes, treatment precision, and procedural efficiency. Key digital technologies under investigation for their potential to augment diagnostic accuracy and optimize implant placement include intraoral scanners, computer-aided design and manufacturing (CAD/CAM), and cone-beam computed tomography (CBCT). The integration of three-dimensional (3D) printing in implantology is also explored, emphasizing its role in accelerating prosthesis fabrication and streamlining clinical workflows. Additionally, the paper delves into the emerging contributions of robotics and artificial intelligence (AI) in enhancing surgical precision and improving implant success rates. The conclusion provides an outlook on the future trajectory of digital implantology, highlighting ongoing technological innovations that hold promise for further advancements in patient care and clinical outcomes.
COMPARISON OF OROPHARYNGEAL LEAK PRESSURE (OLP) OF I-GEL AND BLOCKBUSTER LMA DURING LAPAROSCOPIC CHOLECYSTECTOMY
Full text linkBackground: Supraglottic airway devices (SADs) such as the i-gel and the BlockBuster LMA are widely used in various types of surgeries to provide a secure airway and minimize the complications associated with endotracheal intubation. In laparoscopic cholecystectomy, oropharyngeal leak pressure (OLP) is a key indicator of how well an SAD can maintain a seal under positive pressure ventilation, especially with elevated intra-abdominal pressure during pneumoperitoneum. While several SADs are commercially available, there is a paucity of data comparing the i-gel and the BlockBuster LMA with regard to OLP in laparoscopic cholecystectomy.Methods: A randomized comparative study was conducted in 70 adult patients (ASA I–II, aged 18–45 years) undergoing elective laparoscopic cholecystectomy under general anesthesia. Participants were allocated into two groups of 35 each: Group I (i-gel) and Group B (BlockBuster LMA). The primary outcome was OLP measured at four time points: (1) 1 minute after SAD insertion, (2) 5 minutes after pneumoperitoneum, (3) 30 minutes after pneumoperitoneum, and (4) 5 minutes after release of pneumoperitoneum. Secondary outcomes included peak inspiratory pressure (PIP), ease and time of insertion, hemodynamic changes, and device-related complications.Results: The mean OLP values were significantly higher in the BlockBuster LMA group across all four time points compared to the i-gel group (p < 0.001). However, peak inspiratory pressures and hemodynamic parameters did not differ significantly between the groups (p > 0.05). The time to insert the device and the number of insertion attempts were comparable, and both devices demonstrated good airway quality with no clinically significant difference in complications.Conclusion: The BlockBuster LMA provided higher oropharyngeal leak pressures compared to the i-gel in laparoscopic cholecystectomy. Both devices achieved adequate ventilation and demonstrated comparable safety profiles. The BlockBuster LMA may be preferable in clinical scenarios where higher OLP is desired, although i-gel remains a reliable alternative
THE SOCIAL IMPLICATIONS OF EDUCATION INEQUALITIES IN TAMILNADU
Full text linkEducation is fundamental to the HR improvement and strengthening in the phases of development of a country. Interest in schooling and instructive establishments ought to be seen as a speculation for monetary flourishing. Interest in human resources, deep rooted learning and quality training help in the improvement of society and country. Among the different assets, the significance of schooling in human asset advancement has been perceived overall by every one of the areas of the general public. It is obviously that schooling is the pre-essential for the improvement of a general public, as a significant part of improvement process, instruction could be sensibly great marks of economical turn of events. Through the development of instructive offices has been enormously improved, yet the pace of progress isn\u27t seen as noteworthy to decrease the financial dissimilarity in schooling. The majority of states in India have wide contrasts as far as instructive enrolment including the territory of Tamil Nadu. This paper is to separate the level of uniqueness in enrolment of high level training in Tamil Nadu and the helper data gathered from the picked enlightening estimations of MHRD, Organization of India for the period quite a while from 2011-2022. The Gather Yearly Advancement Pace of enrolment was augmentation at 4. 34% for SC students, 2.17 percent for OBC students, yet it decreases at 7.49 percent for different social affairs during the past 10 years. The Gross Enrolment Proportion of SC and OBC students were essentially augments, yet the student enrolment in high level training of different social occasions were declined. It is out and out noticed that the difference among SC and Non-SC were meanwhile remaining in permission to getting enrolment in high level training. Though, the level of disparity was declining in the GER since the SC student enrolment was rapidly increases during latest quite a while from 2011-2022. This paper has recommended that the Public authority should mention fruitful objective fact procedure on attestation strategy thus ensure the appropriate degree of selection to the SCs student in Secret Educational Establishments, as tutoring foundations have been growing alarmingly in Tamil Nadu. In light of the specific situation, the current paper primarily means to investigate the disparities of training in Tamil Nadu over the timeframe. It attempts to follow the patterns gathering wise and level wise Enlistment, Degree of differences in enrolment in the state; and to offer potential systems for reinforcing the training and the decrease of variations in schooling in the stat
Digital Transformation empowers ESG Performance based on the Mediating Effect of Green Innovation
Full text linkESG (Environmental, Social and Governance) considerations has gained significant attention in business globally due to increased awareness of environmental issues, social inequalities, and Corporate Governance failures (1). In Indian context also, a similar awakening is taking place amongst the corporates. Companies operating in India are increasingly recognizing the imperative nature of aligning their strategies and operations with ESG principles (2). Around the globe most of the developing countries have pledged to carbon neutrality and improving their ESG Performance for sustainability. Upholding the shared vision of a sustainable future for mankind, the Indian government is also dedicated to global climate governance through concrete actions, and has announced enhanced climate commitments including 50 percent of installed electric capacity from non-fossil fuel sources to reach 500 GW by 2030, reducing carbon intensity of the economy by 45 per cent by 2030 and to achieve the target of net zero emissions by 2070 (3). While there is a widespread discussions and research going on Digitalization and how it affects the ESG at the Global level but there is a limited understanding of how Indian companies are following this transformative journey. The present research aimed to highlight the impact of Digital Transformation on ESG Performance through the mediating effect of Green Innovation with special focus on green processes and green products in manufacturing companies in India
Anticancer Potential of Colonial Ascidians Didemnum perlucidum and Lissoclinum bistratum Against MCF-7 Human Breast Cancer Cell Line
Full text linkBackground: Globally, breast cancer is a leading cause of morbidity and mortality, especially among women. Although the results of current treatments have improved, there remains an urgent need to develop new therapeutic agents. A potential source of bioactive substances with potent anticancer effects is marine biodiversity. Marine tunicates are believed to contain a variety of bioactive compounds with the most important anticancer properties. The family Didemnidae of the class Ascidiacea is known to be a highly adaptable source of natural marine chemicals with a wide range of biomedical applications. Materials and Method: This study investigates the cytotoxic effects of crude and fractionated extracts of the marine ascidians Lissoclinum bistratum and Didemnum perlucidum on MCF-7 breast cancer cell lines. The cytotoxic activity was assessed using the MTT assay at different concentrations from 5 to 20 μg/ml. Results and Discussion: The F2 fraction of both the species exhibited the highest activity, and the results showed significant dose-dependent cytotoxicity. F2 of D. perlucidum and L. bistratum had IC50 values of 10.22 μg/mL and 11.80 μg/mL, respectively, which were much lower than those of the crude extracts. Conclusion: These results highlight the potential of D. perlucidum as a source of anticancer drugs, calling for further investigation into its bioactive components for potential therapeutic uses
In-vitro interaction of terbinafine alone and in combination against isolates of Aspergillus Species
Full text linkINTRODUCTION: The infection associated with Aspergillus species causes high morbidity and mortality in immunocompromised patients and the sudden outbreak of the COVID-19 pandemic worsened the situation in the healthcare system. Recent guidelines recommend the use of voriconazole and isavuconazole for the treatment of aspergillosis, but the emergence of Azole-resistant Aspergillus species limits the azole-based treatment approach. The use of antifungal combination therapy might become an emerging alternative strategy for aspergillosis. In our study, we evaluate the terbinafine interaction against Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger, and Aspergillus terreus alone and in combination with other compounds.MATERIAL AND METHODS: In-vitro terbinafine and other compounds activity against the Aspergillus species was assessed using the Disk Diffusion Assay and micro-broth dilution assay, and the Zone of Inhibition results were measured in millimetres with Mean ± Standard Deviation. The assessment of interaction was done by a chequerboard assay, and the interaction was quantified using the Fractional Inhibitory Concentration Index. These methods provide insights into the nature of the interaction, such as synergy, additivity, indifference, or antagonism.RESULTS: The Zone of inhibition of terbinafine against Aspergillus strains ranges between 22.7±0.2 to 41.3±0.2, Ebselen 16.7±0.2 to 29.3±0.2, Amphotericin B 21.2±0.3 to 27.7±0.2, Aerosporine 6.1±0.2 to 12.5±0.2, Ciprofloxacin 6.3±0.3 and Gentamycin sulphate 6.2±0.2. Terbinafine and other compounds show variable activity and the interaction between these compounds is an interesting approach in the treatment of fungal infections.CONCLUSION: The interaction between terbinafine and other compounds is interesting and might be a potential therapeutic approach against invasive Aspergillus infections
An Empirical Analysis of Anxiety and Its Effect on Academic Performance
Full text linkAnxiety is a well-established, significant predictor of academic performance. Academic stress, anxiety, and performance among higher education students are causes for concern. Students often experience nervousness and high tension while giving presentations in front of the classroom. This study aims to investigate the impacts of students’ anxiety levels and emotional balance on their academic performance. The research used the cognitive theory model to analyze the relationship between anxiety levels and academic performance. Anxiety levels were measured using the Classroom Anxiety Measures (CAM) and Generalized Anxiety Disorder scales, while students\u27 academic performance was measured using Grade Point Average (GPA). The research sample comprised 218 college students. The data was analyzed using SPSS and AMOS software. The results indicate that general anxiety, study anxiety, and emotional balance are significantly influencing academic performance. However, test anxiety does not have an impact on academic performance. For future studies, we suggest utilizing a larger sample size to enhance the robustness of the findings
Privacy-Preserving Text Summarization Using Semantic Similarity With Biobert And Clinicalbert For Multiple Medical Documents Leveraging Parallelized High-Performance Computing
Full text linkThe enormous volume of textual data produced by medical documents in the healthcare industry provides insightful information, but it also presents serious privacy, data security, and computational complexity issues. Through the use of parallelized high-performance computing (HPC), this research presents a unique framework for the privacy-preserving text summarization of various medical records utilizing semantic similarity algorithms driven by modified BioBERT and ClinicalBERT. In order to maximize productivity, the framework uses distributed computing environments and secure computation approaches to satisfy the demand for summarizing sensitive medical data while maintaining anonymity. This study shows that the method offers quick and privacy-compliant summarization, protecting patient privacy without sacrificing the information\u27s relevance and semantic accuracy