E-Jurnal Universitas Tunas Husada Tasikmalaya
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ANALISIS POTENSI INTERAKSI OBAT PADA PASIEN HIPERTENSI DI INSTALASI RAWAT INAP RSD GUNUNG JATI CIREBON
Get PDFHipertensi merupakan 10 kasus penyakit terbanyak di Kota Cirebon, dengan jumlah kasus hipertensi di Kota Cirebon pada Tahun 2021 sebanyak 31.073 kasus. Interaksi obat pada pasien hipertensi penting diidentifikasi karena pemberian obat antihipertensi pada umumnya menggunakan lebih dari satu obat dan penggunaan obat-obatnya digunakan dalam jangka waktu yang cukup panjang. Penelitian ini bertujuan untuk mengetahui karakteristik pasien (usia, jenis kelamin, jumlah obat yang dipakai dan penyakit penyerta), mengetahui potensi interaksi obat pasien hipertensi, mengetahui tingkat keparahan potensi interaksi obat (kontraindikasi, serius, monitor atau minor), mengetahui gambaran jenis dan jumlah obat yang berinteraksi, serta faktor yang paling berpengaruh terhadap interaksi obat pasien hipertensi di Instalasi Rawat Inap RSD Gunung Jati Cirebon. Penelitian yang dilakukan adalah penelitian deskriptif observasional dengan data karakteristik pasien (usia, jenis kelamin, jumlah obat yang dipakai, dan penyakit penyerta) secara retrospektif. Sampel penelitian ini adalah rekam medik pasien hipertensi di Instalasi Rawat Inap RSD Gunung Jati Cirebon Tahun 2021 yang memenuhi kriteria inklusi. Analisis hasil berupa gambaran potensi interaksi obat menggunakan Medscape dalam bentuk persentase dan tabel. Hubungan jumlah obat yang digunakan dengan interaksi obat menggunakan uji Fisher’s Exact. Dari 95 pasien hipertensi, yang berpotensi kejadian interaksi obat sebanyak 53 pasien (55,79%) dengan jumlah pasien perempuan sebanyak 48 pasien (50,53%), tingkat keparahan paling banyak terjadi yaitu monitor sebanyak 110 (64,33%). Obat yang paling banyak berinteraksi adalah Furosemide dengan Asam Folat (11,70%). Pasien hipertensi berisiko tinggi mengalami potensi interaksi obat karena jumlah terapi obat yang dikonsumsi serta adanya penyakit penyerta
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 96% DAUN RAMANIA (Bouea macrophylla Griffith) TERHADAP BAKTERI Staphylococcus aureus
Get PDFThe ramania plant (Bouea macrophylla Griffith) is a species of the Anacardiaceae tribe, with different names. Ramania plants (Bouea macrophylla Griffith) are still very limited in their use, namely only as fruits. Ramania leaves (Bouea macrophylla Griffith) empirically have the potential to control the wound healing process. One of the bacteria that can be inhibited by ramania leaves (Bouea macrophylla Griffith) is Staphylococcus aureus. The aim is to determine the results of phytochemical screening of 96% ethanol maceration extract of Ramania leaves (Bouea macrophylla Griffith) and the diameter of the inhibition zone of 96% ethanol extract of Ramania leaves (Bouea macrophylla Griffith) against Staphylococcus aureus bacteria by disc method. 96% ethanol extract of ramania leaves (Bouea macrophylla Griffith) by maceration extraction method with 96% ethanol solvent and extract yield of 8.54%. The 96% ethanol extract of Ramania (Bouea macrophylla Griffith) leaves positively contains alkoloids, flavonoids, streoids, saponins and tannins. Antibacterial activity test was performed with 4 concentration series, i.e. 5%; 10%; 15% and 20%, positive control chloramphenicol 30μg/disc, and negative control DMSO 0.1%. The results of the 96% ethanol ramania leaf (Bouea macrophylla Griffith) antibacterial activity test showed that the 5%, 10%, and 15% concentrations were included in the weak category, with inhibition zones of 1.925 mm, 3.355 mm, and 4.737 mm, respectively, while the 20% concentration was included in the moderate category with an inhibition zone of 5.775 mm. From the results of the study can show that the ethanol extract of 96% ramania leaves (Bouea macrophylla Griffith) has antibacterial activity against Staphylococcus aureus bacteria
ANALISIS KANDUNGAN FLAVONOID DAN FENOLIK TOTAL DARI ESKTRAK DAN FRAKSI TANAMAN BATANG TEBU TELUR (Saccharum Edule Hasskarl)
Get PDFTanamanTebu Telur (Saccharum edule Hasskarl) merupakan sayuran yang termasuk dalam famili Poaceae dengan genus Saccharum dan spesies Saccharum edule Hasskarl. Tebu Telur ini diduga mengandung metabolit sekunder yaitu fenol, flavonoid, tanin, saponin, alkaloid dan steroid. Flavonoid memiliki berbagai efek bioaktif termasuk anti virus, anti-inflamasi kardioprotektif, antidiabetes, anti kanker, anti penuaan, antioksidan. Sedangkan fenolik memiliki kemampuan untuk membentuk radikal fenoksi yang stabil pada reaksi oksidasi yang menyebabkan senyawa fenolik sangat berpotensial sebagai antioksidan. Penelitian ini bertujuan untuk menganalisis kadar flavonoid total dan fenolik total pada ekstrak etanol dan fraksi Batang Tebu Telur. Metode penelitian yang digunakan yaitu analisis uji kualitatif dan kuantitatif menggunakan spektrofotometri UV-Vis serta ditunjang dengan analisis kromatografi cair-Spektrometri Massa. Hasil uji kuantitif ekstrak etanol dan fraksi Batang Tebu Telur terbukti mengandung senyawa flavonoid dan fenolik. Berdasarkan hasil penelitian ini diperoleh kadar flavonoid total sebesar 4,15 mgQE/g pada ekstrak etanol, 5,82 mgQE/g pada fraksi air, 29,35 mgQE/g pada fraksi etil asetat dan 11,46 mgQE/g pada fraksi n-heksana. Sedangkan kadar fenolik total yang diperoleh sebesar 10,96 mgGAE/g pada ekstrak etanol, 19,06 mgGAE/g pada fraksi air, 58,73 mgGAE/g pada fraksi etil asetat dan 34,93 pada fraksi n-heksan
Penentuan Aktivitas Tabir Surya Ekstrak Etanol Daun Salam (Syzigium polyanthum (Wight.) Walp) dengan Metode Spektrofotometri UV-Vis
No full textContinuous contact with UV rays may result in sunburn, wrinkles, dullness, and also skin cancer. Using sunscreen is one technique for minimizing the negative effects of UV radiation. Plants, such as the bay leaf (Syzigium polyanthus), possess the ability to function as natural sunscreens. The bay leaf contains flavonoids, which act as sunscreens. The goal of this research is to investigate the sunscreen activity of a commercially available ethanolic extract of Syzigum polyantum. The initial stage of this study involves screening for phytochemicals to ascertain the presence of secondary metabolites. The sunscreen activity is measured as SPF value using a spectrophotometer uv-vis. The phytochemical test demonstrates that the extract contains flavonoids, tannins, saponins, and steroids
Efek Kombinasi Rebusan Daun Kecombrang (Etlingera elatior (Jack) R.M.Sm.), Daun Kelor (Moringa oleifera Lam.), Daun Salam (Syzygium polyanthum (Wight) Walp.) dan Daun Sirsak (Annona muricata
No full textBackground: Diabetes mellitus has emerged as a major issue in Indonesia and continues to increasein prevalence. Hyperglycemia, or elevated blood glucose levels, serves as a primary marker of diabetes,which is classified into type 1, type 2, gestational, and other types. Herbal remedies, includingkecombrang, moringa leaves, bay leaves, and soursop leaves, are utilized as natural alternatives tohelp regulate blood glucose levels and enhance insulin sensitivity. Objective: To evaluate the effectsof a combination of boiled moringa leaves, kecombrang leaves, soursop leaves, and bay leaves ondiabetic mice. Method: Four types of leaves were combined and boiled at three different doses (13.2mg/20 g body weight of mice, 36.4 mg/20 g body weight of mice, and 72.8 mg/20 g body weight ofmice), then administered orally to male mice for 7 days. Glucose levels were measured using aphotometer for urine glucose and a glucometer for OGTT, FPG, and urine glucose tests. The studyinvolved 24 male mice divided into six groups: a normal group, a positive control group, a negativecontrol group, and three treatment groups receiving dose 1, dose 2, and dose 3. The results wereanalyzed using SPSS version 26 with the One-Way ANOVA test. Results: The results indicated thatthe combination of the boiled leaves significantly reduced hyperglycemia, particularly at dose 2 (36.4mg/20 g body weight of mice), which effectively lowered blood glucose levels and produced effectscomparable to those of the positive control. The dose 2 group also exhibited a significant reduction inblood glucose levels compared to the negative control and demonstrated stable, consistent effects.Conclusion: These findings suggest that the combination of boiled kecombrang, moringa, bay, andsoursop leaves at a dose of 36.4 mg is effective in reducing blood glucose levels in hyperglycemic mice.However, the involvement of the SGLT-2 inhibitor mechanism was not observed
PEMERIKSAAN STATUS GIZI DAN PENYULUHAN JAJANAN SEHAT PADA ANAK DI LKSA AMANAH KOTA TASIKMALAYA
No full textChild development experts state that the first five years of a child’s life represent the "Golden Period," "Window of Opportunity," or "Critical Period." Early detection is a screening effort carried out to identify developmental disorders early and to understand and recognize the risk factors for these developmental disorders. Method : Lecture and nutritional status examination. Results and Discussion : After measuring the nutritional status of 36 individuals, the BMI results showed 20 individuals in the underweight category (55.5%), 15 individuals in the normal category (41.6%), and 1 individual in the obese category (2.7%). Before providing counseling on healthy snacks, participants were given a pre-test questionnaire consisting of 10 questions. The average score for knowledge about healthy snacks was 7.5. After the counseling session, participants were given the questionnaire again as a post-test. The results showed an increase in knowledge about healthy snacks, with an average score of 8.5 and a percentage increase of 10.6%. Conclusion : Among the 36 individuals whose nutritional status was measured, the BMI results showed 20 individuals in the underweight category (55.5%), 15 individuals in the normal category (41.6%), and 1 individual in the obese category (2.7%). There was an increase in knowledge about healthy snacks among participants after the health counseling session, with an average pretest score of 7.5 and an average post-test score of 8.5, resulting in a percentage increase of 10.6%
EFEKTIFITAS PENYULUHAN PENYAKIT INFEKSI JAMUR PADA KULIT DI KABUPATEN CILACAP
No full textFungal infection of the skin is a disease that often occurs in the territory of the Republic of Indonesia due to its tropical climate. Personal hygiene and a humid environment can be a major factor in the occurrence of fungal infections. Fungal infections of the skin are not lethal but interfere with daily activities. The people of Cisalak Hamlet, Adimulya Village, have busy activities and are in an environment with high temperature and humidity which can trigger fungal infections of the skin. The purpose of this counseling is to increase the knowledge of the Cisalak Hamlet community regarding fungal infections of the skin and their prevention. The research method used is the lecture, discussion and evaluation method with 27 respondents. The results of the study showed that there was a significant increase in knowledge of fungal infections of the skin after counseling was carried out
SOSIALISASI DAN PENDAMPINGAN SERTIFIKASI HALAL ABIYU KITCHEN KOTA TASIKMALAYA
Get PDFAbiyu Kitchen currently produces 3 types of products, namely pickled fruit, fruit salad, and pastries. The problem faced by Abiyu Kitchen MSMEs is that they do not yet have halal certificates for all the products they produce. The purpose of this Community Service Activity is to provide knowledge and apply for halal certification to the perpetrators of MSMEs at Abiyu Kitchen. The addition of knowledge and understanding is expected to increase productivity and competitiveness for Abiyu Kitchen MSME players. The method used in this activity is lectures, questions, and answers for the participants of this socialization. The participants of this halal certification socialization activity are Abiyu Kitchen MSME players. Halal certification counseling activities succeeded in significantly increasing participants\u27understanding. This is shown through the activeness and enthusiasm of participants in following the material, and discussions, and answering questions and answers. The evaluation results show an increase in understanding of information on halal certification by 86.36%, knowledge of halal labeling on products by 92.72%, information on how to apply for halal certification by 77.27%, and the benefits of halal certification by 95.45%. benefits of halal certification by 95.45%. In addition, participants also understood the positive impact of halal certification on products, including increased consumer confidence and competitiveness. and competitiveness. This activity shows effectiveness in increasing halal literacy and public awareness of the importance of halal certification
OPTIMALISASI PENGGUNAAN GAME DALAM AKTIVITAS KELAS BAHASA INGGRIS
Get PDFThe use of games is one way to build students\u27 motivation in learning English. The use of games is usually done at the beginning or core activities of learning. However, the application of games can basically be applied in every stage of classroom activities, both in pre-activities, activities, and post-activities. Based on this, the author wants to know how effective the use of games is in every English class activity, both pre-, while, and post-activities, as well as the impact on student involvement in English learning. The methods used in this community service activity are (1) giving a pre-test before the presentation session and (2) presenting presentation topics related to learning scenarios with the use of games both in pre-, while, and post-activities. (3) giving post-test after the presentation session (4) processing and analyzing pre-test and post-test data to produce descriptions and graphic presentations related to the effectiveness of using games in-class activities and their impact on student involvement. There is an effective use of games in the pre-activities stage, which can increase students\u27 motivation to learn English so that they become more interested and ready to engage in learning English. There is an effectiveness of using games in activities that can increase students\u27 understanding of the English material taught so that students become active in interacting during learning activities. Furthermore, there is an effectiveness of using games in post-activities, which can help students strengthen the material that has been learned to create student involvement in obtaining feedback related to the material learned
PENINGKATAN EDUKASI KEPADA MASYARAKAT MENGENAI PENYAKIT DIABETES MELLITUS DAN UPAYA PENCEGAHAN KOMPLIKASINYA
No full textKadar gula darah yang tinggi akibat adanya gangguan sekresi insulin, kerja insulin, atau keduanya merupakan penyakit gangguan metabolisme yang dikenal dengan diabetes mellitus (DM). Kejadian ini erat kaitannya dengan gaya hidup, salah satunya yakni pola makan. Kondisi yang tidak terkontrol dapat mengakibatkan menyebabkan kerusakan pada berbagai organ seperti jantung, ginjal, mata, pembuluh darah dan saraf. Penanganan paling utama adalah mengubah gaya hidup terutama mengatur pola makan yang sehat dan seimbang. Kegiatan Pengabdian Kepada Masyarakat ini dilaksanakan di Wilayah Kota Tasikmalaya oleh Dosen beserta Mahasiswa TK II dan TK, III Prodi D III Keperawatan Fakultas Ilmu Kesehatan Universitas Bakti Tunas Husada, kegiatan berlansung selama semester ganjil 2023/2024. Rangkaian kegiatan berupa konseling dan demonstrasi latihan fisik, detail topik materi yang diberikan adalah tentang menjalani hidup sehari-hari dengan berperilaku sehat dapat mengurangi dampak dari penyakit diabetes melitus. Pelaksanaan Konseling tentang DM, penanganan dan pencegahan komplikasinya dilaksanakan di Cilolohan, Lebaksari Kahuripan Kota Tasikmalaya dan di Cipadung Banjar.. Sasaran kegiatan ini adalah penderita DM dan masyarakat yang memiliki keluarga dengan DM. Metode kegiatan meliputi tahap persiapan, pelaksanaan dan evaluasi. Kegiatan ini dapat terlaksana dengan baik dan lancar, sasaran memahami manajemen penatalaksanaan DM yang meliputi pengecekan kadar gula darah, aktifitas fisik, terapi obat, diet nutrisi dan perawatan kaki. Pemahaman dan pengetahuan masyarakat dalam manajemen penatalaksanaan diabetes mellitus meningkat maka komplikasi penyakit dapat dicegah