Institut Penelitian Matematika Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE): Open Journal System
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Terapi Sel Punca Mesenkimal pada Diabetes Melitus Tipe 2: Tinjauan Sistematis terhadap Outcome HbA1c
Get PDFThis study evaluates the effectiveness of Mesenchymal Stem Cell (MSC) therapy in lowering HbA1c levels among patients with Type 2 Diabetes Mellitus (T2DM). A systematic review was conducted using PubMed, ScienceDirect, and Google Scholar with the keywords “Type 2 Diabetes Mellitus,” “Mesenchymal Stem Cell,” and “HbA1c,” covering studies published between 2022–2025. Four primary studies met the inclusion criteria, involving 438 patients treated with MSCs from various sources. Most studies reported significant HbA1c reduction after MSC infusion, particularly with UC-MSC therapy, which showed a decrease of over 1% within 48 weeks. The effect was more pronounced in patients with a shorter diabetes duration (≤10 years) and lower BMI (<23 kg/m²). The conclusion is that MSC therapy has been proven to improve glycemic control with a favorable safety profile. However, further large-scale and long-term studies are needed to confirm its effectiveness and determine the optimal clinical application.
Keywords: Type 2 Diabetes Mellitus, HbA1c, Mesenchymal Stem Cel
Implementasi Pemberian Daun Seledri (Apium Graveolens.L) dalam Penurunan Kadar Asam Urat & Nyeri pada Pasien Lansia
Get PDFThis study aimed to evaluate the effectiveness of celery leaf decoction on reducing uric acid levels and pain intensity in two elderly patients in the Pasar Sentral Community Health Center (Puskesmas) area. The study used a descriptive method with a case study approach. Results showed a reduction in pain from 5 to 3 on the Numeric Rating Scale (NRS), as well as a decrease in uric acid levels, as measured by point-of-care testing (POCT). This intervention also increased daily activity and supported healthy lifestyle changes in patients. In conclusion, celery leaf decoction is effective in reducing uric acid levels and pain in elderly patients with hyperuricemia.
Keywords: Apigenin, Apiin, Gout, Celery Leaves, Non-pharmacological Intervention
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Persepsi Pasien Asam Urat terhadap Penggunaan Obat Tradisional
Get PDFThis study aims to explore gout patients\u27 perceptions of the use of traditional medicine in the Wania Community Health Center (Puskesmas) working area in Mimika Regency. The method used was qualitative, employing descriptive phenomenology. Based on thematic analysis used in data processing, five main themes were identified: (1) type of traditional medicine used (herbal concoctions, massage), (2) reasons for use (natural, minimal side effects, economical), (3) perceived effectiveness (reducing pain and swelling), (4) obstacles (difficulty in preparing, ingredients not always available), and (5) support and expectations (recognition and support from health facilities). In conclusion, patient perceptions of traditional medicine are influenced by culture, economics, accessibility, and personal experience. Nurses are expected to implement culturally sensitive nursing care and integrate patient beliefs into health education.
Keywords: Gout, Nursing, Qualitative, Traditional Medicine, Perceptio
Analisis Puasa Praanestesi dengan Kejadian Haus Praanestesi
Get PDFThis study aimed to analyze the relationship between fasting duration, type of anesthesia, and surgical duration with the incidence of thirst in pre-anesthetic patients at Welas Asih Regional General Hospital, West Java Province. The method used was an observational analytic approach with a cross-sectional approach. The results showed that the majority of respondents were female (58.8%), with the highest fasting duration being 6–8 hours (64.7%), mild thirst intensity (54.1%), and no signs of dehydration (81.2%). Statistical tests showed a significant association between fasting duration (p=0.018; OR=2.45) and surgical duration (p=0.043; OR=1.97) with thirst intensity. While the type of anesthesia had no effect (p=0.214). In conclusion, fasting duration and surgical duration influence the intensity of thirst in pre-anesthetic patients, while the type of anesthesia has no effect.
Keywords: General Anesthesia, Surgical Duration, Pre-anesthetic Fasting, Thirs
Digital Marketing Strategy Via Tiktok Social Media to Increase Brand Awareness in Friendzone Barbershop in Bulo Village Sidenreng Rappang District
Get PDFThis study aims to analyze digital marketing strategies through TikTok social media in increasing brand awareness at Friendzone Barbershop in Bulo Village, Sidenreng Rappang Regency. The research method used is a descriptive qualitative approach with data collection techniques through in-depth interviews, observation, and documentation of ten informants consisting of business owners, customers, youth leaders, and non-customers selected using purposive sampling techniques. The results of the study indicate that the use of TikTok as a digital marketing medium is able to increase brand awareness of Friendzone Barbershop through creative and interactive promotional content. The implemented digital marketing strategies, including providing incentives, digital displays (site design), cost management, and interactivity, have a positive contribution to brand awareness indicators, namely recall, recognition, purchase, and consumption, although there are still several aspects that need to be improved to encourage consistent purchases and consumption. The conclusion is that the digital marketing strategy through TikTok social media plays an important role in increasing brand awareness of Friendzone Barbershop and is an effective solution in expanding market reach and strengthening business competitiveness amidst the limitations of a less strategic location.
Keywords: Digital Marketing, TikTok, Brand Awareness, Barbershop, Social Medi
Hubungan Antara Motivasi Kerja Dengan Kinerja Perawat Rawat Inap Di Rumah Sakit Umum Daerah X
Get PDFThe purpose of this study was to determine the relationship between work motivation and the performance of inpatient nurses at Regional General Hospital X. The study design used a quantitative method with a cross-sectional approach. The study sample consisted of 88 nurses selected using a purposive sampling technique. Data were analyzed using the Chi-square test. The results showed that the majority of respondents had high work motivation (59.1%) and high performance (70.5%). The statistical test obtained a p-value of 0.000 (<0.05) with an odds ratio (OR) of 7.185, indicating a significant relationship between work motivation and the performance of inpatient nurses. It can be concluded that nurses with high work motivation have a greater chance of demonstrating optimal performance. Therefore, improving work motivation needs to be a priority in human resource management strategies in hospitals.
Keywords: Nurses, Performance, Work Motivation.
Penelusuran Senyawa Inhibitor Alpha-Glukosidase Potensial untuk Diabetes Melitus Tipe 2 melalui Pendekatan In Silico dengan Evaluasi Profil Adme Via SwissADME.
Get PDFThe aim of this study was to demonstrate data retrieval from online databases to find compounds with relevant properties such as alpha-glucosidase inhibitors, which have the potential to be used in the treatment of Type 2 Diabetes Mellitus. The methods used included compound search, physicochemical property analysis, and drug-likeness prediction using Lipinski\u27s Rule of Five as well as ADME profile evaluation using the SwissADME platform. Preliminary results showed that Miglitol and Quercetin have promising drug-likeness profiles, comply with Lipinski\u27s Rule of Five, and exhibit good ADME characteristics. Although Acarbose, as an effective drug, does not meet all Lipinski criteria due to its specific mechanism of action. The conclusion of this study confirms the efficiency of the in-silico approach in the initial screening of drug candidates but requires further experimental validation to confirm its activity and safety.
Keywords: ADME, Alpha-Glucosidase Inhibitor, Drug-Likeness, In Silico, SwissADME, Type 2 Diabetes Mellitus
Pengembangan Media Pembelajaran Leap Motion Materi Pengenalan Hewan untuk Meningkatkan Motorik Anak Usia Dini
Get PDFThis study aims to develop an interactive learning medium based on Leap Motion, namely LeapZoo: Zoo-Based Educational Game, which is designed to improve early childhood motor skills through virtual animal recognition. The method used was research and development (R&D) with the ADDIE model, focusing on the design and development stages. Validation was carried out by media, language, and early childhood education experts to assess technical and pedagogical feasibility. The results showed that LeapZoo is feasible to be used as a learning medium in early childhood education. In conclusion, gesture-based interactions such as stroking and feeding animals can stimulate children’s fine and gross motor coordination and align with Vygotsky’s theory, which emphasizes the role of social interaction and digital scaffolding in the zone of proximal development.
Keywords: Early Childhood, Gesture-Based Learning, Leap Motion, Learning Media, Motor Skills, Animal Recognitio
Pengembangan Media Pembelajaran Scrapbook untuk Meningkatkan Motivasi Belajar Siswa pada Mata Pelajaran Pendidikan Agama Islam di SDN 112 Kabupaten Seluma
Get PDFThis study aimed to develop a learning media in the form of a scrapbook to enhance students\u27 learning motivation in the Islamic Religious Education subject at SDN 112, Seluma Regency. The method used is Research and Development (R&D) with the Four-D (4-D) model, which consists of four main stages: Define, Design, Develop, and Disseminate. The research subjects were fifth-grade students of SDN 112 Seluma, and data were collected through observation, interviews, questionnaires, and documentation. The results show that: (1) the validity of the scrapbook media based on expert validation was 85% for media experts, 81% for material experts, and 88% for language experts, categorized as very valid; (2) the practicality of the scrapbook learning media based on student responses averaged 93%, categorized as very practical; and (3) students\u27 interest in the scrapbook learning media averaged 89%, categorized as very high. In conclusion, the scrapbook learning media can improve the learning motivation of fifth-grade students at SDN 112 Seluma.
Keywords: Islamic Religious Education, Learning Media, Learning Motivation, Scrapbook, Elementary Schoo
Pengaruh Pemberian ZPT Ekstrak Kecambah Kacang Hijau dan Pestisida Nabati Ekstrak Lidah Buaya Terhadap Pertumbuhan Vegetatif Tanaman Tomat (Solanum lycopersicum)
Get PDFThis study aimed to determine the effects of various concentrations of growth regulators (ZPT) derived from mung bean sprout extract on the vegetative growth of Solanum lycopersicum, as well as the effect of aloe vera extract–based botanical pesticide on pest infestation intensity, either independently or in combination. The study employed a two-factor randomized block design consisting of ZPT concentrations (0%, 20%, 30%, 40%, 50%) and botanical pesticide concentrations (0%, 15%, 40%, 65%, 90%), each with three replications. The results showed that mung bean sprout extract–based ZPT significantly affected all vegetative growth parameters. The 50% concentration produced the greatest plant height (72.93 cm) and number of leaves (70.47), while the highest number of branches was obtained at the 20% (12.67) and 40% (12.53) concentrations. The botanical pesticide made from aloe vera extract significantly reduced pest infestation intensity, with the 65% and 90% concentrations classified as light damage (<25%), while the control (0%) showed very severe damage (>85%). The findings indicate that mung bean sprout–based ZPT effectively improves vegetative growth, and aloe vera–based botanical pesticide effectively suppresses pest attacks; however, their separate application is more optimal for achieving specific targets.
Keywords: Pests, Botanical Pesticide, Vegetative Growth, Solanum lycopersicum, ZPT