e-Journal Badan Penelitian dan Pengembangan Kesehatan / National Institute of Health Research and Development
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PERILAKU PENCARIAN PENGOBATAN ODHA DAN TERAPI ARV DI KALANGAN PECANDU NARKOBA SUNTIK
No full textPeople living with the HIV/AIDS (PLWH) in Indonesia is increasing every year. Injecting drug users (IDUs) is one of groups who contribute the HIV/AIDS cases in Indonesia. IDU group is at risk of double transmission through needles and risk sexual activities. Yet, still a lot of them do not have antiretroviral therapy. The study aimed to elaborate health seeking behaviour among IDUs with HIV/AIDS in relation to have the antiretroviral therapy. It is a qualitative study. Data were collected mainly by indepth interview. The data were analyzed descriptively. Informants are people living with HIV/ AIDS among injecting drug user group in Surabaya and Jakarta Cities. Results show that a lot of IDUs have not ARV therapy yet. The causes are knowledge on side effects of the ARV therapy is not right, low self-efficacy among the PLWH with IDUs are mostly they still face addiction problems, their perception that they are still healthy, and difficulty to follow procedure of theARV therapy. Those who take the ARV therapy are who have had perception that the therapy is advantages and believe could follow the therapy. It concludes that the awareness among the PLWH with IDU to have the AVR therapy is low. Health seeking behavior of the PLWH with IDU are influenced by the perception on severity of the diseases, the perception on advantages and difficulties on the therapy, and also the PLWH with IDU beliefs on the success of the therapy. To increase the PLWH with IDU, it needs to enhance information and to educate the PLWH with IDU on the ARV therapy. ABSTRAK Orang dengan HIV/AIDS (ODHA) di Indonesia jumlahnya semakin meningkat dari tahun ke tahun salah satunya adalah kelompok pecandu narkoba suntik (penasun). Kelompok penasun memiliki risiko penularan ganda melalui jarum suntik dan hubungan seks berisiko. Namun ODHA dari kelompok penasun masih banyak yang belum mengikuti terapi Antiretroviral (ARV). Studi ini bertujuan mengkaji gambaran perilaku pencarian pengobatan pada ODHA di kelompok penasun dan keikutsertaan dalam terapi ARV. Metode penelitian ini adalah kualitatif. Pengumpulan data terutama dengan wawancara mendalam. Analisis data secara deskriptif. Informan adalah kelompok ODHA penasun di Kota Surabaya dan Jakarta. Hasil penelitian ini adalah ODHA penasun, banyak yang belum mengikuti terapi ARV. Penyebabnya adalah pengetahuan yang tidak tepat mengenai efek samping terapi ARV, kurangnya self-efficacy ODHA penasun terutama yang masih adiksi, persepsi bahwa mereka masih sehat sehingga belum membutuhkan terapi ARV, serta prosedur terapi ARV yang berbelit. Mereka yang mengikuti terapi ARV adalah yang sudah memiliki persepsi bahwa terapi ARV benar-benar bermanfaat dan yakin dapat mengikuti terapi ini. Kesimpulan penelitian ini adalah kesadaran ODHA penasun mengikuti terapi ARV masih rendah. Perilaku pencarian pengobatan ODHA penasun dalam mengikuti terapi ARV dipengaruhi oleh persepsi keparahan penyakit, persepsi terhadap manfaat dan hambatan terapi ARV serta keyakinan ODHA penasun terhadap keberhasilan terapi. Untuk meningkatkan jumlah ODHA penasun yang mengikuti terapi ARV, perlu peningkatan pemberian informasi dan edukasi terhadap ODHA penasun untuk mengubah persepsi ODHA penasun terhadap terapi ARV.
Penggunaan Metode Jaring Penghalang (Barrier) sebagai Metode Alternatif Koleksi Nyamuk Anopheles di Lapangan
No full textMetode jaring penghalang (barrier) merupakan metode alternatif koleksi nyamuk, meminimalkan kontak kolektor terhadap gigitan nyamuk. Penelitian bertujuan memperkenalkan metode jaring penghalang sebagai metode alternatif koleksi nyamuk di lapangan. Penelitian dilakukan di Kabupaten Pesawaran dan Kabupaten Lampung Selatan, Provinsi Lampung, bulan Januari sampai Juni 2011. Jaring penghalang berukuran 25x2 meter dibentangkan dengan penyangga bambu, dipasang di daerah yang memisahkan habitat perkembangbiakan nyamuk Anopheles dengan pemukiman penduduk. Hasil penangkapan nyamuk di Kabupaten Pesawaran dengan metode jaring penghalang; An. subpictus 72,5 per orang per malam; An. sundaicus, 20,51 per orang per malam; An. barbumbrosus 0,13 per orang per malam. Penggunaan metode umpan orang luar (UOL) di Kabupaten Pesawaran, An. tesselatus 23,75 per orang per malam; An. sundaicus 11,25 per orang per malam. Hasil penangkapan nyamuk di Kabupaten Lampung Selatan dengan metode jaring penghalang, An. sundaicus 1,25 per orang per malam; An. vagus 1 per orang per malam; An. annularis dan An.subpictus 0,25 per orang per malam. Sedangkan dengan metode umpan orang luar (UOL) di Kabupaten Lampung Selatan, An. sundaicus 150,625 per orang per malam bulan Mei, bulan Juni An. tesselatus 54,375 per orang per malam. Kesimpulannya, metode jaring penghalang (barrier) dapat dijadikan metode alternatif dalam memperbanyak koleksi nyamuk istirahat di luar rumah. Kata kunci: jaring penghalang, metode alternatif, koleksi nyamuk Anopheles ABSTRACT Barrier net was introduced as alternative method for mosquitoes collection to minimize mosquitoes bites to collectors. The aim of study was to introduce barrier net, as alternative method for collecting mosquitoes in field. The study was conducted in Pesawaran and South Lampung Regency, Lampung Province, from January to June 2011. Barrier net was 25x2 meters expanded, and tied by bamboo. Barrier net was installed in area, separated from breeding habitats of Anopheles to communities. The result showed that in Pesawaran Regency, caught by barrier net, An. subpictus 72,5 per person per night; An. sundaicus 20,51 per person per night; An. barbumbrosus 0,13 per person per night. Otherwise, by outdoor human landing collection, An. tesselatus 23,75 per person per night and An. sundaicus 11,25 per person per night. In South Lampung Regency, caught by barrier net, An. sundaicus 1,25 per person per night; An. vagus 1,0 per person per night; An. annularis and An. subpictus 0,25 per person per night, while, by outdoor human landing collection, An. sundaicus 150,625 per person per night on May, whereas, on June, An. tesselatus 54,375 per person per night. The conclusion was, barrier net could be as alternative method for getting mosquitoes resting collection. Keywords: barrier net, alternative method, Anopheles mosquitoes collection
Aspek Kekinian tentang Penelitian Demam Berdarah Dengue di Pulau Jawa dan Sekitarnya
No full textIncidence Rate/IR DBD di Indonesia pada tahun 2015 sampai 2017 menurun 44,43%, meskipun tahun 2016 terjadi peningkatan 53,61% dari rerata kejadian DBD tahun 2015 (IR DBD per 100.000 penduduk tahun 2015 sampai 2017 adalah 50,75; 77,96; 22,55). Lima subsistem yang berkaitan dengan penularan DBD yaitu manusia, virus dengue, nyamuk Aedes, lingkungan fisik, dan biologis. Penelitian tentang kelima subsistem dan berbagai upaya pengendalian telah dilakukan di Indonesia. Tulisan ini merupakan literature review yang membahas hal tersebut. Wilayah pencarian pada situs ejournal.litbang.kemkes.go.id, portalgaruda.org, e-resources.perpusnas.go.id, www.hindawi.com, www.researchgate.net, dan who.int dengan kata kunci Aedes aegypti dan Demam Berdarah Dengue. Beberapa penelitian menunjukkan hasil yang berbeda tergantung kondisi lokasi (iklim, ketinggian tempat, kondisi ekologi). Perilaku manusia terkait penggunaan obat anti nyamuk, virus dengue yang ditemukan di alam, Aedes sebagai vektor (tempat perkembangbiakan potensial, transovari, resistensi vektor terhadap insektisida), serta kondisi iklim (suhu dan kelembaban) yang mendukung turut berkontribusi terhadap kejadian DBD. Pengendalian vektor merupakan upaya penanggulangan DBD yang efektif. Penggunaan Bacillus thuringensis, Romanomermis iyengari dan Wolbachia, pembuatan repelen dan larvasida dari berbagai tanaman, peningkatan perilaku masyarakat terkait PSN, serta aplikasi teknik serangga mandul dikembangkan dari berbagai penelitian. Hasil-hasil penelitian tersebut dapat diadopsi sebagai alternatif untuk mengendalikan vektor dan dilaksanakan secara terpadu berdasarkan konteks lokal spesifik. Kata kunci: Aedes aegypti, demam berdarah, Indonesia, penelitian ABSTRACT Incidence Rate/IR DHF in Indonesia 2015 to 2017 decreased 44.43%, although in 2016 there was an increase of 53.61% from incidence in 2015 (DHF IR per 100,000 population in 2015 until 2017 was 50,75;77,96; 22.55). Five subsystems related to DHF transmission are human, dengue virus, Aedes mosquito, physical and biological environment. Research on these five subsystems and various control efforts has been done in Indonesia. Literature review was used to discuss it in this article. Search area on the site ejournal.litbang.kemkes.go.id, portalgaruda.org, e-resources.perpusnas.go.id, www.researchgate.net, www.hindawi.com and who.int with keywords Aedes aegypti, Dengue Haemorhagic Fever. Several studies showed different results depending on the study site conditions (climatic,altitude,ecological conditions). Human behavior associated with the use of anti-mosquito, dengue virus, Aedes as a vector (potential breeding places, transovary phenomena, insecticide vector resistance), and climate conditions (temperature and humidity) that contribute to the incidence of DHF. Vector control is the most effective measure in DHF control program. The use of Bacillus thuringensis, Romanomermis iyengari, and Wolbachia, the manufactured repellents and larvasides from various plants, the improvement of eradication of mosquito breeding sites related community behavior, and the application of sterile insect techniques have been developed from various studies. The results of such research can be adopted as alternative to control vectors and implemented in integrated manner based on the specific local context. Keywords: Aedes aegypti, dengue fever, Indonesia, researc
STATUS IODIUM PADA ANAK USIA SEKOLAH 6 – 12 TAHUN DI DAERAH DENGAN NILAI EKSKRESI IODIUM URIN (EIU) TINGGI
No full textIodine deficiency or excess lead to the impairment of hormone production and thyroid function, and in the long term can cause health problems. Epidemiological criteria to determine the severity of Iodine Deficiency Disorders (IDD) in an area can be done by assessing the iodine status of school-age children. Indicator that can be used includes urinary iodine concentration (UIC). Indication of excess iodine in school-age children in some parts of Indonesia has been reported, among others, in Demak and Blora Regency, while on the other hand, the number of households consume enough iodized salt are low. Exploring the iodine status of school-age children aged 6-12 years in areas with high UIC values in non endemic iodine deficiency areas. The study was conducted in Blora and Demak Regency, Central Java. Samples were 300 school children aged 6-12 years. Variables: iodine status (thyrotropin hormone, urinary iodine concentration and thyroid gland enlargement). Other variables: nutritional status, nutrient intake, iodine in drinking water, iodine intake sources, iodine in salt. The median value of urinary iodine in Demak regency –were 4266 μg/L in Pidodo Village and 6216 μg/L in Sampang Village. In Blora Regency was 333 μg/L - Japah Village with 54.7% of subjects were at risk of iodine excesses. Hypothyroid subjects were found 24%, 16% and 10% in Sampang, Pidodo and Japah Village respectivelly. The Proportion of non-visible goiter in Demak Regency was more than 30% where in Japah Village was only 5.5%. The high urinary iodine concentration in Blora Regency was suspected as the results of iodized salt intake. However the high urinary iodine in Demak Regency (Pidodo and Sampang Village) was not caused by iodine high intake, but probably from another cause that needs to be further studied
Toksisitas Ekstrak Metanol Daun Jeruk Nipis (Citrus aurantifolia) Terhadap Larva Nyamuk Aedes aegypti Instar III
No full textPenyakit vektor yang ditularkan oleh nyamuk Aedes aegypti dipertimbangkan sebagai masalah kesehatan yang serius di dunia. Penggunaan insektisida kimia untuk mengontrol nyamuk Ae. aegypti dapat menyebabkan resistensi pada populasi nyamuk, masalah kesehatan, dan masalah lingkungan. Ekstrak dari daun jeruk nipis (Citrus aurantifolia) dapat digunakan sebagai alternatif larvasida Ae. aegypti. Tujuan dari penelitian ini adalah untuk mengetahui toksisitas ekstrak metanol (CH3OH) daun jeruk nipis (C. aurantifolia) terhadap larva Ae. aegypti dan melihat visualisasi kerusakan yang terjadi pada tubuh larva Ae. aegypti setelah paparan ekstrak 24 jam. Penelitian eksperimen laboratorium dengan enam konsentrasi dan lima kali ulangan. Kematian larva dihitung setelah 24 jam perlakuan. Data yang diperoleh selanjutnya dianalisa dengan probit. Hasil penelitian menunjukkan (1) ekstrak dapat menyebabkan mortalitas larva dengan LC50 dan LC99 setelah 24 jam adalah 2.197 ppm dan 4.266 ppm. (2) ekstrak dapat menyebabkan kerusakan morfologi tubuh larva Ae. aegypti seperti saluran pencernaan rusak, kepala (cephal) lepas, bulu (setae) lateral hilang, gumpalan ekstrak dalam tubuh, leher panjang, dan tubuh transparan
Penerapan Peraturan Desa Tentang Penemuan dan Pengawasan Pengobatan Kasus Malaria Berbasis Masyarakat
No full textABSTRACT, Purbalingga is one of malaria-endemic areas in Central Java. In 2012, government developed a model of malaria control as Village Regulation for detection and Monitoring of Malaria treatment with Community-Based Treatment of Malaria Cases. Research aim is to evaluate the Regulation (Perdes) effectiveness on the incidence of malaria in Tetel. This research is an evaluation study of the policy with qualitative method. The research conducted in Tetel, Pengadegan District, Purbalingga, in March to October 2015. The datas collected by in-depth interviews on community leaders and health care workers, focus group discussion (FGD) on a group of men and women, and documents review. Datas were analyzed using content analysis. The Regulation socialized through village health forum meetings and other group meetings. Malaria case detection have done by the community that reported to JMD to immediately take blood preparations. Monitoring of malaria treatment by JMD with follow-up action. Cases of malaria in Tetel tends to decrease even to zero after implementation of the regulation. The implementation of regulation can reduce and control the incidences of malaria in Tetel. Implementation of regulation also can be used as an example for other villages that still have problems with malaria.
KONDISI TUMBUH KEMBANG ANAK DENGAN RIWAYAT HIPOTIROID PASCA PENATALAKSANAAN DI BP2 GAKI MAGELANG
No full textClinical management for children with developmental disorder, including laser puncture, medical treatment, nutrition, psychological counseling, or physiotherapy, had been instigate by BP2GAKI. There was no previous research on evaluating the long term outcome of children growth and development who had completed the clinical management in BP2GAKI. Objectives of this study are to investigated the long term effect of therapy administered in BP2GAKI, which were growth, development, hypothyroidism clinical sign, and iodine status. This study was observational with a cross sectional study conducted in BP2GAKI Magelang on 2008. Sample of this study were 44 children based on sample size of Dahlan, patients in BP2GAKI clinique from the year 2002-2005 who completed treatment with ≥40 times therapy and TSH level of ≥5 μIU/mL. Growth status were measured with anthropometrical data of weight and height, developmental data were assessed with Denver 2. Indicators significant of hypothyroid were assessed with clinical score, and iodine status was measured with TSH level. Data was analyzed with chi square test. The result is nutritional status within normal category was increased from 47.73% to 68.18%. Before treatment all children was developmental delayed. Recent data showed that normal motor development was increased significantly to 63.64% (p<0.05 (95% CI: 0.818-7.851). The normal social and language development were increased significantly to 38.64%. Clinical categories with normal score decreased significantly from 45.46% to 40.91% (p<0.05; 95% CI: -0.965-(-0.81). The normal iodine state was 56.82% and children with hypothyroid was decreased significantly from 100% to 43.18% (p<0.05 (95% CI: 0.461-0.748). There was improvement in nutritional status, motor, language, and social development in children long term after treatment in BP2GAKI. Improvement also found in iodine status, but clinical score for hypothyroid was worsen
KAJIAN AWAL POTENSI TUMBUHAN OBAT, ANTI KANKER, ANTI HIV DARI TAMAN NASIONAL KERINCI-SEBLAT The preliminary study of medicinal plant from Kerinci Seblat National Park as anti cancer and anti HIV
No full text.ABSTRACTIndonesia has long been known as a mega biodiversity country, which can be explored its various functionssustainably. Unfortunately, such natural treasury has been neglected, even though it contains many naturalsubstances for medical uses that can generate significant economical advantages and increase human welfare.Plants generally develop defence mechanisms againts herbivores and pathogens through both mechanicalstructures and secondary compounds. The later can be explored for their pharmaceutical uses. The objective ofthe study is to preliminary asses the potential of Kerinci-Seblat as a source for natural substances for medical uses.A plot of 1 ha was established and all trees with > 5 cm were measured, and collected their herbarium specimens,and identified. The results show 27, 147, and 11 tree species potentially contain Benzyl-isoquinoline (BI), Ellagicacid and proanthocyanins (EL&P), and Iridoid (Ir), respectively. These substances can be used to fight heartrelateddisorder, diabetics, and to develop natural-based drugs for antioxidants, anti virus, and anti depresants.Natural substances within sixteen families and 54 species can be further developed into anti cancer drugs, while10 families and 37 species contain potential substances that can be used to fight HIV. ABSTRAKIndonesia telah lama dikenal sebagai negara dengan keanekaragaman jenis yang sangat besar yangdapat dieksplorasi secara berkelanjutan untuk berbagai fungsi. Sayangnya kekayaan alam tersebut telahdiabaikan, meskipun memiliki potensi atas berbagai senyawa alami untuk keperluan pengobatan yang dapatmenghasilkan keuntungan ekonomi yang signifikan dan meningkatkan kesejahteraan manusia. Tanamanumumnya mengembangkan mekanisme pertahanan terhadap desakan herbivora dan patogen baik melaluistruktur mekanik dan senyawa sekunder. Senyawa metabolit sekunder ini dapat dieksplorasi untuk keperluanfarmasi. Tujuan dari penelitian ini adalah untuk mengkaji secara awal potensi Taman Nasional Kerinci Seblatsebagai sumber bahan alami untuk keperluan medis. Plot seluas 1 ha dibuat dan semua pohon dengan ukurandiameter > 5 cm diukur, dan dikumpulkan spesimen herbariumnya, kemudian diidentifikasi. Hasil dari kajianini menunjukkan bahwa berturut turut sebanyak 27 spesies pohon mengandung Benzyl-isoquinoline (BI),147 spesies mengandung ellagic acid dan proanthocyanins (EL & P), dan 11 spesies mengandung Iridoid (Ir).Zat ini dapat digunakan untuk melawan gangguan yang berhubungan dengan jantung, penderita diabetes,dan untuk mengembangkan obat alami berbasis antioksidan, anti virus, dan anti depresants. Zat alami dalamenam belas famili dan 54 spesies dapat dikembangkan lebih lanjut menjadi obat anti kanker, sedangkan 10famili dan 37 spesies mengandung zat yang berpotensi untuk digunakan melawan HIV.Kata kunci: antikanker, antiHIV, Kerinci Sebla
GAMBARAN JUMLAH DAN HITUNG JENIS LEUKOSIT SERTA WAKTU JENDAL DARAH PADA TIKUS BETINA YANG DIINDUKSI 7,12-Dimetilbenz(α)antrasen (DMBA) SETELAH PEMBERIAN EKSTRAK ETANOL BIJI JINTEN HITAM (Nigella sativa L) The number of total leucocyte and coagulation time
No full text ABSTRACTBreast cancer is the second most common female cancer in Indonesia, after the cervical cancer. Imunity can beaffected the growth of cancer and reached by increasing the coagulation and total leucocyte. One of the naturalimunomodulator is Nigella sativa seeds. The research aimed to identify the effect of Nigella sativa to coagulationtime, total and differential leucocyte of Sprague Dawley female rats induced 7,12-dimetilbenz(a)anthracena(DMBA). The rats divided into 6 groups, each consisted of 6 rats. Group I administered DMBA in corn oil 20 mg/kgbw 10 times (2 times a week during 5 weeks). Group II administered corn oil equal to Group I. Group VI administeredImboost® everyday during 7 weeks. Group III, IV and V administered ethanolic extract of N. sativa 5 ,25 and125 mg/kg bw during 7 weeks. Group III-V were induced by DMBA. At 16th week, the blood taken trough orbitalicsinus. The parameters of this research are the coagulation time, total and differential leukocyte. For assessing count of total leucocyte was used “manual direct” method, and for the differential leucocyte was used Differentialcounter cell method. The results showed ethanolic extract dose 5 mg/kg bw, 25 mg/kg bw, 125 mg/kg bw increasethe total lymphocyte, DMBA increase the total monocyte and all of the dose group do not effect to the eosinophyl.Neutrophil band and basophyl do not find. Ethanolic extract dose 5 mg/kg bw and 125 mg/kg bw can increasethe coagulation time, but not at dose 25 mg/kg bw.ABSTRAKKanker payudara merupakan jenis kanker di urutan kedua yang diderita wanita Indonesia setelah kankerserviks. Sistem imunitas dapat mempengaruhi perkembangan penyakit kanker. Kondisi imunitas tercapaidengan baik melalui peningkatan waktu koagulasi dan leukosit total. Salah satu tumbuhan dengan khasiatimunomodulator adalah biji Nigella sativa L. (jinten hitam). Penelitian ini bertujuan untuk mengetahui efekbiji jinten hitam terhadap waktu koagulasi serta leukosit total dan diferensiasinya pada tikus betina SpragueDawley yang diinduksi 7,12-Dimetilbenz(α)antrasen (DMBA). Tikus dibagi 6 kelompok, masing-masing terdiri6 ekor. Kelompok I sebagai kontrol negatif, diberikan DMBA 2 kali seminggu dosis 20 mg/kg BB dalam minyakjagung selama 5 minggu. Kelompok II sebagai kontrol pelarut, diberikan hanya minyak jagung dengan dosisdan cara yang sama dengan kelompok I. Kelompok III, IV dan V adalah kelompok perlakuan ekstrak etanol bijijinten hitam berturut-turut sebesar 5, 25, dan 125 mg/kg bb selama 7 minggu. Kelompok VI sebagai kontrolpositif, diberikan Imboost® selama 7 minggu. Kelompok II-VI diberikan DMBA dengan dosis, frekuensi, dancara yang sama dengan kelompok I. Pada minggu ke-16 darah diambil dari sinus orbitalis. Parameter penelitianini adalah waktu koagulasi, leukosit total yang ditentukan dengan metode “manual direct”, serta leukositdiferensial dengan metode “differential counter cell”. Analisa statistik menunjukkan pemberian DMBA dapatmeningkatkan monosit total tapi tidak berpengaruh pada eosinofil. Pita neutrofil dan basofil tidak ditemukandalam penelitian ini. Perlakuan ekstrak etanol semua dosis dapat meningkatkan level limfosit total. Ekstrakdosis 5 dan 125 mg/kg bb meningkatkan waktu koagulasi, sedangkan dosis 25 mg/kg bb tidak berpengaruhterhadap waktu koagulasi.Kata kunci: Nigella sativa L., leukosit, waktu koagulasi, DMB
KAJIAN ETNOBOTANI DI BEBERAPA KAWASAN HUTAN CAGAR ALAM, JAWA TIMUR Ethnobotanical study in some nature reserve area in East Java
No full text.ABSTRACTAn ethnobotanical study to collate information on the utilization of medicinal trees by local community living inand surround the forest was conducted in four nature reserves areas located in East Java region. Data collectionwas carried out using direct observation in the field, interview with local people and literature study. The existenceand potency of medicinal trees recorded in the research sites are relatively high. However, local people onlyutilize few of these species. Most knowledge of traditional medicine was passed from generation to generationverbally and there was no written documentation made. Evidence from the field showed that this tradition wasno longer existed as only few people, mostly the old one, still kept the knowledge but rarely practice them. Localpeople are currently more familiar with modern medicine available in traditional market compare to traditionalmedicine due to easy access to the market and cheap price. People would gradually ignore these potential treesas less attention are given to the promotion of traditional medicine as well as the declining of the species due toforest degradation. This paper would explore how local forest community in Java utilize the potential medicinaltree species from the nearby forest for health maintenance and whether there is an opportunity to commercializesome of the most common medicinal plant species used by community for alternative income ABSTRAKKajian etnobotani untuk mengumpulkan informasi tentang pemanfaatan tumbuhan obat dilakukan di empatlokasi desa di kawasan hutan alam yang ada di Jawa Timur. Pengumpulan data dan informasi ini diperolehmelalui pengamatan langsung di lapangan, wawancara langsung dengan penduduk lokal serta melalui studipustaka. Keberadaan dan potensi jenis tumbuhan obat di lokasi penelitian cukup banyak. Namun demikianmasyarakat yang berada di sekitar lokasi penelitian memanfaatkan hanya sebagian jenis tumbuhan tersebutsebagai obat. Sebagian besar masyarakat hutan memperoleh pengetahuan tentang ramuan obat tradisionalsecara turun temurun dari generasi ke generasi. Namun hal ini tampaknya semakin menurun mengingat semakinkecilnya jumlah orang yang mengetahui tentang pemanfaatan tumbuhan atau pohon sebagai bahanobat. Masyarakat setempat lebih menyukai obat modern (non-tradisional) yang mudah diperoleh denganharga murah di pasar lokal ketimbang obat tradisional. Lambat laun masyarakat akan meninggalkan pengobatantradisional akibat kurangnya promosi serta semakin berkurangnya jenis-jenis tumbuhan obat akibatterjadinya kerusakan hutan. Makalah ini akan menggali sampai sejauh mana masyarakat yang tinggal di dalamdan sekitar hutan di pulau Jawa masih memanfaatkan tumbuhan obat yang ada untuk menjaga kesehatan danmencari kemungkinan atau peluang untuk melakukan komersialisasi terhadap beberapa jenis tumbuhan obatyang masih digunakan oleh masyarakat sebagai salah satu alternatif sumber pendapatan.Kata kunci: etnobotani, tumbuhan obat, tradisional, kesehata