Islamic University of Gaza

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    Cancer cell detector based on a slab waveguide of anisotropic, lossy, and dispersive left-handed material

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    "Cancer is a disease that takes place when human cells grow uncontrollably. When detected and cured early, it can be non-life-threatening. It becomes life-threatening in case of late discovery where it affects the ability of an organ to function. In this work, a symmetric slab waveguide sensor is analyzed for the detection of cancer cells. The covering layers are assumed anisotropic lossy dispersive left-handed materials. Different from other sensors in which the analyte is located in the cladding region where the evanescent field exists, the cancerous cell is placed in the guiding film region that supports the oscillating field. Hence, the proposed sensor avoids the acute weakness of conven- tional optical waveguide sensors. Due to the high localization of the electromagnetic wave in the analyte region, the proposed sensor shows unusual sensitivity enhancement. The results revealed that the sensitivities obtained are 110%, 325%, and 450% for the first, second, and third modes, respectively. The enhancement of the sensitivity of the third mode relative to the conventional waveguide sensors is nearly a factor of 18.""Cancer is a disease that takes place when human cells grow uncontrollably. When detected and cured early, it can be non-life-threatening. It becomes life-threatening in case of late discovery where it affects the ability of an organ to function. In this work, a symmetric slab waveguide sensor is analyzed for the detection of cancer cells. The covering layers are assumed anisotropic lossy dispersive left-handed materials. Different from other sensors in which the analyte is located in the cladding region where the evanescent field exists, the cancerous cell is placed in the guiding film region that supports the oscillating field. Hence, the proposed sensor avoids the acute weakness of conven- tional optical waveguide sensors. Due to the high localization of the electromagnetic wave in the analyte region, the proposed sensor shows unusual sensitivity enhancement. The results revealed that the sensitivities obtained are 110%, 325%, and 450% for the first, second, and third modes, respectively. The enhancement of the sensitivity of the third mode relative to the conventional waveguide sensors is nearly a factor of 18.

    التحقيق العددي لجهاز الاستشعار القائم على رنين البلازما السطحي الموضعي (LSPR) لمراقبة مستوى الجلوكوز

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    This study aims to apply Localized Surface Plasmon Resonance (LSPR), Maxwell Garnett’s formula, and Fabry-Perot theory together to design and develop a LSPR enhanced gold colloidal nanoparticles (AuNPs) sensor to be used in biomedical applications such as detection of glucose level in urine for early stage screening of diabetic patients. In this work, the LSPR based sensor has been designed and studied numerically to detect the glucose level from the change in the effective index resulting in a red shift of the absorption peak. The sensors were designed to have various sizes of the gold nanoparticles in a range between 20 nm and 100 nm by having different molar ratio with Trisodium Citrate (TSC) which acts as stabilizer in the synthesis. The maximum possible sensitivity of the sensor can be achieved with 70 nm diameter of gold nanoparticles at 0.2 volume fraction of AuNP to glucose solutionتهدف هذه الدراسة إلى تطبيق الرنين الموضعي لسطح البلازمون (LSPR) ، وصيغة ماكسويل غارنيت ، ونظرية فابري-بيرو معًا لتصميم وتطوير مستشعر الجسيمات النانوية الغروية الذهبية (AuNPs) المعزز بـ LSPR لاستخدامه في التطبيقات الطبية الحيوية مثل الكشف عن مستوى الجلوكوز في البول للفحص المبكر لمرضى السكري. في هذا العمل ، تم تصميم المستشعر المعتمد على LSPR ودراسته عدديًا للكشف عن مستوى الجلوكوز من التغير في المؤشر الفعال مما أدى إلى تحول أحمر في ذروة الامتصاص. تم تصميم المستشعرات بحيث تحتوي على أحجام مختلفة من جسيمات الذهب النانوية في نطاق يتراوح بين 20 نانومتر و 100 نانومتر من خلال وجود نسبة مولارية مختلفة مع سترات الصوديوم (TSC) التي تعمل كمثبت في التوليف. يمكن تحقيق أقصى حساسية ممكنة للمستشعر بقطر 70 نانومتر من جزيئات الذهب النانوية عند 0.2 جزء حجم من AuNP إلى محلول الجلوكو

    Occurrence of gastrointestinal helminthes in commercial and free-range chickens in Gaza Strip, Palestine

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    The present study compared the prevalence of helminthes parasites in two chicken breeds in Gaza strip, the commercial and the free-range indigenous. Gastrointestinal tracts of 100 commercial growers and 90 free-range indigenous chickens collected from Gaza city were examined for helminthes during 2007–2008. The commercial chickens were free of helminthes while the indigenous chickens were encountered five helminthes, three nematodes and two cestodes .The nematodes identified were Ascaridia galli (75.6%), Heterakis gallinarum (68.9%) and Capillaria spp. (2.2%). The cestodes were, Raillietina echinobothrida (57.8%) and Choanotaenia infundibulum (26.7%). No trematode was found. The intensity of parasites was low except for H. gallinarum. It was concluded that the indigenous chickens were infected with some types of cestodes and nematodes in Gaza markets. Sanitations and public health should be of concerned for both health authorities, consumers and farmers owners

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    Prevalence of intestinal parasites and microbial contamination in common edible vegetables used in Gaza Governorate, Palestine

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    The present study was conducted to assess the extent of contamination with human intestinal parasites and to determine the bacterial quality in commonly vegetables in Gaza Governorate. A total of 320 vegetable samples which included dill, Jew’s mallow, lettuce, parsley, peppermint, rocket, and spring onion were collected from the local markets in Gaza and examined for their contamination with human intestinal parasites and bacteria. These vegetables were processed by parasitological and microbial standard methods. The present study showed that 118 samples out of 320 were contaminated with human parasites with a prevalence rate of 36.9%. The lowest contaminated vegetable was spring onion at 3.43% and the highest contaminated one was Jew’s mallow (6.87%). The most recovered parasite was the nematode Strongyloides stercoralis, which has a percent rate 17.2%. Coliform, fecal coliform, and Escherichia coli were detected in high percentage of the tested vegetables. Six vegetable samples were contaminated with Cryptosporidium sp. It is concluded that the fresh commonly used vegetables in Gaza governorate were contaminated with intestinal parasites and bacteria. Measures and inspection of the commonly used fresh vegetables by health authorities should be regular in Gaza community

    Diagnosis of gastrointestinal parasites among hospitalized patients attending Al-Nasser Paediatric Hospital, Gaza, Palestine.

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    Aims: The aim of this study was to determine the prevalence of the dignosed gastrointestinal parasites among hospitalized children attending the Al-Nasser Paediatric Hospital. Method: This was a cross sectional study among hospitalized children attending the Al-Nasser Paediatric Hospital. The study included 522 children during the period May 2002 to May 2003. Data collection included two methods: medical laboratory results for the examination of stool specimens and a questionnaire. wet mount using saline and Lugol's iodine and formal ether sedimentation techniques were employed in the present stydy. Results: Evidence for infection with gastrointestinal parasite was found in 176 ( 33.7% of the children. The intestinal parasite were most prevalent in femals ( 38.8% . The most higly prevalent parasite was found to be Entamoeba histolytica/dispar ( 26.4% and the monthly high prevalence of intestinal parasite was in Februrary ( 54.5% . The prevalence of intestinal parasites increased significantly with increasing age for both Giardia lamblia and E. histolytica/dispar. Conclusions: The study showed a high prevalence hospitalized children. Hygiene and health measures should be reviewed in the hospital where nosocomial infection cannot be excluded. The diagnostic techniques for stool specimens should be reviewed and improved. Physicians in hospitals and private clinics should be aware of intestinal parasite diseases when requesting stool specimens znd prescribing drugs

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