Archivio Istituzionale della Ricerca- Università del Piemonte Orientale
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Polyphenols promote stem cell surface adaptation onto low-adhesion chitosan-titanium through protein synthesis and cytoskeletal remodeling
Pragmatica storica dell’italiano: ieri, oggi, domani
The aim of this paper is twofold: it seeks to provide both an introduction to the volume and a reasoned overview of the historical pragmatics of Italian, which constitutes the thematic and methodological thread uniting the contributions of this special issue. The paper offers a critical synthesis of key findings from previous studies in historical pragmatics, with particular focus on the Italian language, and re-evaluates the current state of the field along with recent trends in diachronically oriented pragmatic research on Italian, through which the contributions in this issue may also be contextualized. Drawing on these observations, the paper con-cludes with a discussion of a set of desiderata intended to guide the future develop-ment of the disciplin
Laparoscopic versus open liver resection for large (≥ 5 cm) hepatocellular carcinoma in elderly patients: a multicenter propensity score-matched study
: The outcomes of laparoscopic liver resection (LLR) for large (≥ 5 cm) hepatocellular carcinoma (HCC) in elderly (≥ 70 years old) patients have not been deeply investigated so far. The aim of the study was to compare short- and long-term results of LLR vs. open liver resection (OLR) in this setting. Data regarding all patients undergoing liver resection for large HCC were retrospectively collected from referral European and Asian HPB centers. The cases were propensity score matched for age, BMI, center, underlying liver cirrhosis, comorbidities, extent of the resection, tumor size, and numbers. After matching 363 patients with large HCC aged ≥ 70 years old, two cohorts of 90 patients were compared. The laparoscopic group showed a shorter median length of hospital stay (7 vs 9 days, p = 0.01), with a lower rate of R1 resections (4.4% vs 13.3%, p = 0.03). No statistically significant differences were found in the median operative time (p = 0.34), intraoperative blood transfusions (p = 1.00), severe postoperative complications (p = 0.29), postoperative hemorrhage (p = 0.30), post-hepatectomy liver failure (p = 0.47), or in-hospital mortality (p = 0.31). After a median follow-up of 35 months (95% CI 27.6-42.3), there were no statistically significant differences in both overall survival (p = 0.28) and disease-free survival (p = 0.42). LLR was safe and effective in selected cases of large HCC in elderly patients and was proven to shorten median hospital stay and to reduce the R1 rates, without affecting both short- and long-term survival outcomes
Light neutral-meson production in pp collisions at sqrt(s) = 13 TeV
The momentum-differential invariant cross sections of π0 and η mesons are reported for pp collisions at = 13 TeV at midrapidity (|y| < 0.8). The measurement is performed in a broad transverse-momentum range of 0.2 < pT< 200 GeV/c and 0.4 < pT< 60 GeV/c for the π0 and η, respectively, extending the pT coverage of previous measurements. Transverse-mass-scaling violation of up to 60% at low transverse momentum has been observed, agreeing with measurements at lower collision energies. Transverse Bjorken x (xT) scaling of the π0 cross sections at LHC energies is fulfilled with a power-law exponent of n = 5.01 ± 0.05, consistent with values obtained for charged pions at similar collision energies. The data are compared to predictions from next-to-leading order perturbative QCD calculations, where the π0 spectrum is best described using the CT18 parton distribution function and the NNFF1.0 or BDSS fragmentation function. Expectations from PYTHIA8 and EPOS LHC overestimate the spectrum for the π0 and are not able to describe the shape and magnitude of the η spectrum. The charged-particle multiplicity dependent π0 and η pT spectra show the expected change of the spectral shape, characterized by a flatter slope with increasing multiplicity. This is demonstrated across a broad transverse-momentum range and up to events with a charged-particle multiplicity exceeding five times the mean value in minimum bias collisions. The η/π0 ratio depends on the charged-particle multiplicity for pT< 4 GeV/c. PYTHIA8 and EPOS LHC qualitatively explain this behavior with an increasing contribution from the feed-down of heavier particles to the π0 spectrum
Il trasporto merci attraverso i valichi alpini svizzeri: transizione modale e scenari futuri
Which trial do we need? Combination regimen for individuals exposed to multidrug-resistant Mycobacterium tuberculosis
Designing the biodiversity-friendly city of the future: An avian community perspective on land sharing and land sparing
J/ψ-hadron correlations at midrapidity in pp collisions at sqrt{s} = 13 TeV
We report on the measurement of inclusive, non-prompt, and prompt J/ψ-hadron correlations by the ALICE Collaboration at the CERN Large Hadron Collider in pp collisions at a center-of-mass energy of 13 TeV. The correlations are studied at midrapidity (|y| < 0.9) in the transverse momentum ranges pT< 40 GeV/c for the J/ψ and 0.15 < pT< 10 GeV/c and |η| < 0.9 for the associated hadrons. The measurement is based on minimum bias and high multiplicity data samples corresponding to integrated luminosities of Lint = 34 nb−1 and Lint = 6.9 pb−1, respectively. In addition, two more data samples are employed, requiring, on top of the minimum bias condition, a threshold on the tower energy of E = 4 and 9 GeV in the ALICE electromagnetic calorimeters, which correspond to integrated luminosities of Lint = 0.9 pb−1 and Lint = 8.4 pb−1, respectively. The azimuthally integrated near and away side yields of associated charged hadrons per J/ψ trigger are presented as a function of the J/ψ and associated hadron transverse momentum. The measurements are discussed in comparison to PYTHIA calculations