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Treatment of Interface Fluid Syndrome after Laser-Assisted In Situ Keratomileusis with Descemet Membrane Endothelial Keratoplasty in Three Patients with Corneal Endothelial Dysfunction
Descemet Membrane Endothelial Keratoplasty (DMEK) has become a first-line treatment in corneal endothelial
diseases owing to its exceptional clinical outcomes and low complication rates. Thanks to its refractive predictability and the
ability to reshape the superficial cornea, DMEK is now also considered for managing cases with endothelial decompensation
following previous refractive procedures. This article reviews the clinical outcomes of DMEK in three patients with Interface
Fluid Syndrome (IFS), a complication of laser-assisted in situ keratomileusis (LASIK) in which endothelial failure can play
a major role.Medicin
Urinary Electrophoretograms Performed by Capillary Electrophoresis: Comparison between Dogs and Cats
L.G., P.F.N. and S.F.-B. designed the study; M.W. and L.G. collected the data
and checked them from the laboratory information system; M.W. and P.F.N. processed the samples;
L.G. and P.F.N. wrote the paper and analyzed and interpreted the data. All authors have read and
agreed to the published version of the manuscript.Electrophoresis of urine to evaluate different urinary proteins has been used in recent years
in veterinary medicine, as it can be a useful laboratory tool in the early detection of kidney damage.
However, urinary capillary electrophoresis (UCE) has not been reported in healthy cats. In healthy
dogs, reference intervals have been established and can be compared with pathological samples as
these provide an easily interpretable pattern. The electrophoretogram in this study is divided into five
fractions (F1–F5) by serum (albumin; alpha1-globulin; alpha2-globulin; beta-globulin; and gammaglobulin).
Urine samples from 14 healthy cats were obtained by eco-guided cystocentesis. UCE was
run in all samples and compared to 123 dog electrophoretograms from a previously published study.
Fraction 2 (alpha1-globulin) was statistically decreased in cats (G1) compared to dogs (G2). Fraction 4
(beta-globulin) was statistically augmented in cats compared to the canine population (G2). Fraction
5 (gamma-globulin) was statistically decreased in cats (G1) compared to dogs (G2). No statistical
correlation was found between each cat’s serum and urinary fractions. The results of the present
study suggest that UCE patterns in cats are similar to the ones described in dogs. UCE can be a
non-invasive new diagnostic tool in cats as pathological patterns can be compared to normal onesVeterinari
Case Report: Role of Anterior Segment Optical Coherence Tomography for Managing Failed Endothelial Keratoplasty Graft
Author Contributions: Conceptualization: MJR-R, CP-M;
Investigation: MJR-R; Methodology: MJR-R, CO-P; Supervision:
CP-M; Writing – Original Draft: MJR-R;
Writing – Review & Editing: EA-G, CP-M.SIGNIFICANCE: Some patients show poor visual outcomes after Descemet stripping automated endothelial keratoplasty.
In such cases, secondary Descemet membrane endothelial keratoplasty can be performed to achieve complete
visual recovery. Anterior segment optical coherence tomography (AS-OCT) is a valuable tool for the follow-up of
posterior lamellar keratoplasty outcomes and complications.
PURPOSE: This study aimed to report the clinical outcome of secondary Descemet membrane endothelial keratoplasty
formanaging poor visual results in a patient with graft failure after a previous Descemet stripping automated
endothelial keratoplasty, highlighting the importance of AS-OCT in the follow-up of endothelial keratoplasty.
CASE REPORT: A 38-year-old woman with highmyopia underwent Descemet stripping automated endothelial keratoplasty
for bullous keratopathy after explantation of an angle-supported phakic intraocular lens. Two years after
keratoplasty, the patient experienced poor visual acuity (counting fingers), and significant corneal edema was observed
on clinical examination hindering visualization of the anterior chamber structures. Anterior segment optical
coherence tomography showed a failed and thickened graft adhering well to the recipient cornea in an anterior
chamber without other comorbidities. Therefore, the graft was removed and replaced with a Descemet membrane
endothelial keratoplasty graft without any complications. One year later, the clinical outcome was evaluated by
comparing the pre-operative and post-operative best-corrected visual acuity, biomicroscopy findings, endothelial
cell density, and corneal central thickness.
CONCLUSIONS: Anterior segment optical coherence tomography is an important tool when deciding on the surgical
technique to be applied and for the post-surgical monitoring of endothelial corneal grafts. This case demonstrates
the successful management of Descemet stripping automated endothelial keratoplasty graft failure with
Descemetmembrane endothelial keratoplasty graft, highlighting the importance of AS-OCT in detecting complications
such as graft dislocation and primary graft failure. In addition, corneal thickness measured using AS-OCT
serves as a critical predictor of graft failure, as observed in this case.Medicin
Acompañamiento y evangelización de la religiosidad popular mariana
Hace algunas décadas se intentó relegar
la piedad del pueblo por ignorancia,
desprecio o rechazo. Acompañar en verdad,
con caridad pastoral, la fe sencilla y
evangelizarla con propuestas y orientaciones
muy concretas.
"Gaudium et Spes" y "Lumen Gentium"
abrieron cauces para la teología y la pastoral.
"Evangelii Nuntiandi" y "Evangelii Gaudium",
con realismo y caridad pastoral,
aportan propuestas y orientaciones para
evangelizar la religiosidad popular.A few decades ago, an attempt was
made to relegate the piety of the people out
of ignorance, contempt or rejection. To accompany
the simple faith in truth, with
pastoral charity, and to evangelize it with
very concrete proposals and orientations.
"Gaudium et Spes" and "Lumen Gentium"
opened channels for theology and pastoral
care.
"Evangelii Nuntiandi" and "Evangelii
Gaudium", with realism and pastoral charity,
provide proposals and guidelines for
evangelizing popular religiosity.Religió
Las apariciones de Jesús resucitado: relato, historia, teología Aparición sobre una montaña de Galilea: misión universal (Mt 28,16-20)
El Resucitado, al aparecerse a las mujeres, confirma el mensaje que éstas deben transmitir a los discípulos. Nos narra después esa aparición a los discípulos en Galileay convierte esta aparición en el auténtico punto culminante de toda la historia pascual (Mt 28,16ss).The Resuscitated, by appearing to the women, confirms the message that they must transmit to the disciples. He then narrates this apparation to the disciples in Galilee and makes this apparation into the true culmination of the whole Paschal story (Mt 28:16ff).Religió
A glimpse into relapsed refractory multiple myeloma treatment in real-world practice in Spain: the GeminiS study
The aim of this study is to describe the incorporation of monoclonal antibodies (mAb) in real-world (RW)
practice for the treatment of patients with relapsed refractory multiple myeloma (RRMM) in a
setting with other treatment alternatives.This study was sponsored by Janssen-Cilag. Janssen-Cilag
participated in the study design, data analysis and drafting
of the manuscript. All investigators received financial com-
pensation for their participation in the study.Medicin
“Quid mihi et tibi est, mulier?” (Jn 2,4). El tratamiento de María en el evangelio de Juan en las traducciones de la Biblia al chino (s. XVIII-XX)
Uno de los problemas a los que se enfrentaron las misiones a China desde su llegada fue la aparente incompatibilidad entre determinados preceptos confucianos y el mensaje cristiano. En lo que respecta a la traducción del Nuevo Testamento, algunos de los pasajes más susceptibles de herir las susceptibilidades locales son Jn 2,4 y Jn 19,26, en los que Jesús se dirige a María como “mujer” en vez de “madre”. En el presente estudio analizamos las soluciones que se han dado a esta cuestión en un amplio corpus de traducciones de la Biblia al chino realizadas por católicos, protestantes y ortodoxos.One of the issues missionaries encountered upon their arrival in China was the apparent incompatibility between certain Confucian precepts and the Christian message. With regards to translations of the New Testament, Jn 2:4 and Jn 19:26stand out as two of the passages most likely to upset local sensibilities due to the fact that Jesus addresses Mary as “woman” as opposed to “mother”. In this paper I will discuss the solutions that have been proposed to overcome this issue by analyzing alarge corpus of Catholic, Protestant and Orthodox translations.Religió
Regenerar España renovando su catolicismo: la posición de Ortega y Gasset
Desde la segunda mitad del siglo XIX hasta el primer tercio del XX, varios movimientos doctrinales y no pocas personalidades del pensamiento, trabajaron y centraron sus esfuerzos en construir una España mejor, una España que no fuera a la zaga de los demás países europeos y que recuperara el esplendor cultural de siglos pasados. Para estos movimientos y personalidades era un hecho incuestionable que España se encontraba en plena decadencia, es decir, que estaba gravemente enferma y que sólo podría recuperar la salud mediante una enérgica revitalización espiritual, moral y política; para muchos de ellos era convicción firme, avalada por la historia, que España había adquirido su fisonomía propia como pueblo y su peculiar personalidad al calor del catolicismo; y, por ello, no pocos tenían por evidente que su anhelada regeneración pasaba necesariamente por un cambio profundo en la mentalidad católica y en la Iglesia.From the second half of the 19th century until the first third of the 20th century, several doctrinal movements and not a few intellectuals worked and focused their efforts on building a better Spain, a Spain that would not lag behind other European countries and that would recover the cultural splendour of past centuries. For these movements and personalities it was an unquestionable fact that Spain was in the throes of decadence, that is, that it was seriously ill and could only recover its health through an energetic spiritual, moral and political revitalisation; for many of them it was a firm conviction, backed by history, that Spain had acquired its own physiognomy as a people and its peculiar personality in the heat of Catholicism; and, for this reason, not a few considered it evi-dent that its longed-for regeneration would necessarily require a profound change in the Catholic mentality and in the Church.Religió
Biocompatible Chitosan Films Containing Acetic Acid Manifested Potent Antiviral Activity against Enveloped and Non-Enveloped Viruses
Author Contributions: Á.S.-A.: conceived the idea for this work, designed the experimental procedure, supervised, acquired funding, investigated, performed project administration, oversaw
resources, wrote the draft manuscript, prepared figures, performed major editing and reviewed and
proofread the manuscript. A.C.-V.: investigated, undertook data curation, performed experiments,
wrote the draft manuscript, prepared figures. A.T.-M.: investigated, performed experiments. M.M.:
investigated, performed experiments and performed editing. All authors have read and agreed to the
published version of the manuscriptChitosan films were prepared by solvent casting using an acetic acid-based solution.
The films that were developed contained 15.49% of acetic acid solution (10% v/v) and showed
biocompatibility in vitro in human keratinocyte HaCaT cells and potent antiviral activity against
both enveloped and non-enveloped viruses. The results showed up to 99.98% and 99.92% viral
inactivation against the phi 6 enveloped bacteriophage and MS2 non-enveloped bacteriophage,
respectively, suggesting that this chitosan/acetic acid film is a promising material for biomedical
applications that require biodegradable broad-spectrum antiviral materialsBiotecnologí
Fit to the rasch model of the FEEL-KJ Spanish adaptation
In recent decades, scientific production related to Emotional Regulation (ER) has increased significantly. Deficits in ER have been linked
to various mental health problems. The aim of this work is to evaluate the Spanish adaptation of the Feel-Kj scale to the RASCH model.Psicologí