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Recuperación simbólica y arquitectura sagrada en el complejo industrial S.A. Cros en Valencia (España)
No full textThe reuse of abandoned industrial spaces is a crucial challenge in contemporary urban regeneration. The case of the S.A. Cross complex in Valencia offers a particularly significant example, with the conversion of one of its warehouses into a place of worship. Originally part of a fertiliser factory active between the 19th and
20th centuries, the warehouse has been transformed into a church, preserving its industrial spatial and material features while reinterpreting them through new symbolic and functional codes. This unusual yet emblematic intervention highlights the narrative potential of industrial heritage and its ability to accommodate contemporary
forms of sacredness. This article examines the architectural, cultural, and social value of such a transformation, exploring the design strategies adopted to balance historical memory, urban identity, and spiritual function. The warehouse-church of the S.A. Cross complex thus emerges as a paradigm of adaptive reuse capable of generating
new meanings and responding in a sustainable and creative way to the needs of local communities
Process Transformation at the University of Basilicata: Mapping, Digitalization, and Enhanced Transparency
No full textDigital transformation in higher education requires the redesign of administrative and teaching processes to improve efficiency, transparency, and accountability. This study analyzes and optimizes the process of Supplementary Teaching Assignments (ADI) at the University of Basilicata, integrating Business Process Modeling and Notation (BPMN 2.0) with discrete-event simulation using the Simul8® tool. The proposed Process Innovation in Higher Education (PIHE) Framework combines process mapping, simulation-based validation, and KPI-oriented monitoring to identify inefficiencies and guide evidence-based process reengineering. Simulation results highlight that the Didactics Office represents the primary process bottleneck, absorbing over 30% of the total workload, and that Department Council scheduling has a significant impact on overall lead time. Optimizing these factors reduces completion time by up to 8% while enhancing resource allocation and service quality. Although the analysis focuses on a single university, which limits external generalizability, the proposed PIHE Framework offers an adaptable methodological structure that can be transferred to other higher education institutions operating under different organizational and regulatory contexts. Future research will extend its application to multiple universities and additional administrative processes to strengthen its empirical validation and support data-driven decision-making in academic governance
FLOWS: a web-based physically-based model for one-dimensional water flow and solute transport simulations in heterogeneous agricultural and environmental systems
No full textAcque, dighe, elettricità. Inedite sperimentazioni nella Basilicata del primo Novecento
No full textn the wake of Nitti’s innovative concepts between the 19th and 20th centuries, the essay reconstructs the unpublished history of the planning of Lucanian reservoirs within the framework of the plans outlined by the special legislation for Basilicata in 1904. The need to ensure energy supply, no longer through the exploitation of coal, but through the construction of plants for hydroelectric power production, triggered an important planning phase that was supposed to lead to the creation of artificial reservoirs to collect and exploit the abundant waters of the Lucanian rivers. These realizations, not exclusively aimed at meeting the needs of Lucania, were supposed to generate hydroelectric energy to be distributed to a large part of the continental South: an ambitious and innovative program that, however, would have been realized in the second half of the 20th century. Thanks to the documentation of the Civil Commissariat for Basilicata, it has been possible to demonstrate how Francesco Saverio Nitti’s ideas were already influencing southern policy at the beginning of the century. His vision combined environmentalist logic with visionary plans for industrial development, in an attempt to rescue the South from the stagnant situation into which an excessively conservative policy risked relegating it
A Semi-automatic Pipeline for the Decay Mapping and the State of Conservation Assessment of Architectural Heritage Through Point Clouds
No full textThe integration of automation and artificial intelligence has revolu-tionized the documentation, conservation, and restoration of architectural cultural heritage. This research presents a pipeline leveraging Machine Learning (ML) algorithms for the automatic decay mapping of digitalized architectures, com-bined with informative system to support experts in the assessment of a synthetic index of the conservation state. Moreover, the setup of a web-based system as a platform for the expert acknowledgment and management of decays and proper-ties helps them in a fast and coherent final assessment. The proposed pipeline combines such technologies to the architectural recovery theories and ensures a standardized procedure compliant with international and national regulations and standards such as ICOMOS-ISCS Glossary and UNI 11182:2006, UNI 8290-1:1981 and UNI CEN/TS 17385:2019. Method and tools are applied to the Lab-riola Palace in Tursi, Italy, demonstrating its efficacy in assessing the conserva-tion state of architectural heritage, as well as the higher collaborative levels to reach also among technicians with different levels of computer science skill
A Transatlantic Perspective on Interoperability and Platform Design after Android Auto: the Luxembourg effect?
No full textAn RBF-based Nyström method for Second–Kind Fredholm Integral Equations
No full textThe aim of this paper is to numerically solve Fredholm Integral Equations (FIEs) of the second kind, when the right-hand side term and the kernel are known only at scattered sample points. The proposed method is of the Nyström type and leverages a cubature rule based on Radial Basis Function (RBF) interpolation, with the Leave-One-Out Cross-Validation (LOOCV) technique used to select the optimal RBF shape parameter. The convergence of the method is proven in the space of continuous functions. Finally, numerical tests demonstrate the performance of the method for various RBF choices and provide direct comparisons with other RBF-based techniques for FIEs available in the literature
Repurposing major metabolites of lamiaceae family as potential inhibitors of α-synuclein aggregation to alleviate neurodegenerative diseases: an in silico approach
No full textNeurodegenerative disorders (NDs) are typically characterized by progressive loss of neuronal function and the deposition of misfolded proteins in the brain and peripheral organs. They are molecularly classified based on the specific proteins involved, underscoring the critical role of protein-processing systems in their pathogenesis. Alpha-synuclein (α-syn) is a neural protein that is crucial in initiating and progressing various NDs by directly or indirectly regulating other ND-associated proteins. Therefore, reducing the α-syn aggregation can be an excellent option for combating ND initiation and progression. This study presents an in silico phytochemical-based approach for discovering novel neuroprotective agents from bioactive compounds of the Lamiaceae family, highlighting the potential of computational methods such as functional networking, pathway enrichment analysis, molecular docking, and simulation in therapeutic discovery. Functional network and enrichment pathway analysis established the direct or indirect involvement of α-syn in various NDs. Furthermore, molecular docking interaction and simulation studies were conducted to screen 85 major bioactive compounds of the Lamiaceae family against the α-syn aggregation. The results showed that five compounds (α-copaene, γ-eudesmol, carnosol, cedryl acetate, and spathulenol) had a high binding affinity towards α-syn with potential inhibitory activity towards its aggregation. MD simulations validated the stability of the molecular interactions determined by molecular docking. In addition, in silico pharmacokinetic analysis underscores their potential as promising drug candidates, demonstrating excellent blood-brain barrier (BBB) permeability, bioactivity, and reduced toxicity. In summary, this study identifies the most suitable compounds for targeting the α-syn aggregation and recommends these compounds as potential therapeutic agents against various NDs, pending further in vitro and in vivo validation
Conversano e il territorio a Sud-Est di Bari tra tardoantico e altomedioevo. Visibilità e invisibilità dei dati archeologici e delle fonti.
No full textAlthough landscape archaeology research indicates significant
improvements in the knowledge of rural settlement patterns from the Roman
and Late Antiquity periods in the central part of Puglia, the territory of Conversano,
despite the absence of systematic archaeological surveys, offers the
possibility of investigating and recognizing some long-term trend lines that
seem to characterize rural settlements between the 7th and 12th centuries.
The territory is characterized, at least since the Middle Ages, by a relatively
large extension of documentary sources from which a rich and articulated
network of rural settlements emerges, never investigated in a systematic
way before.
The contribution, therefore, is divided into two integrated and complementary
analytical levels: the identification of known archaeological contexts
and the topographic contextualization of documents in relation to toponymy
and historical cartography, supported by the implementation of data in a GIS
platform. The study has allowed us to identify a close connection between
Roman and medieval settlements, which were very well integrated into a
complex environmental framework, characterised by a fair amount of economic
vitality, which allowed the area to become part of the Mediterranean
trade routes first, and then regional ones, embedding itself into long-term
commercial traffic which seems to favour this area