24663 research outputs found
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Innovative methods for the detection and quantification of Listeria monocytogenes clones in food matrices
Ultrasonographic and elastographic evaluation of the canine cervix across oestrous cycle stages
Former Food and Agro-Industrial By-Products in Dairy Cow Diets: Effects on Milk Quality and Cheese Production
The use of former foodstuff and by-products in cow diets could improve the environmental sustainability of livestock. However, knowledge about the effects of these feeds in ruminant diets on the quality of dairy products is lacking. This study investigated the effects of integrating wheat distillers’ grain with solubles (WDGS) and a former foodstuff product (FFP) into the diet of dairy cows on milk and cheese quality. The environmental impact of the two feeding systems has been evaluated by LCA. A double crossover design was set up with 84 Holstein cows, alternating a control diet and a circular one. In the circular diet, traditional feeds were partially replaced with 4 kg/d WDGS and 3 kg/d FFP. The results showed no effects on dry matter intake and milk yield, while fiber digestibility improved. A reduction in the milk fat content and a modification of the fatty acid profile of milk and cheese were observed. Conversely, cheese yield, composition, and sensory attributes were not affected. The environmental impact of the diet was significantly reduced in terms of land occupation, net fresh water, and global warming potential. These findings suggest that these feeds can be safely included in dairy cow diets. This approach could significantly contribute to reducing greenhouse gas emissions, enhancing the sustainability of the dairy system
Evaluation of physiological changes in Mytilus galloprovincialis exposed to an isothiazolinone-based compound: A multi-marker approach
The present study aims to assess, through a multi-marker analysis, the changes in physiological parameters in the Mediterranean mussel, Mytilus galloprovincialis, due to exposure to methylchloroisothiazolinone (CMIT). The CMIT is an isothiazolinone-based compound widely employed in the formulations of several commercial products as a biocidal agent. The increasing use of isothiazolinones, especially during the COVID-19 pandemic, has increased concerns about the health of the ecosystem. Therefore, in the present study, specimens of M. galloprovincialis were exposed to environmentally relevant sub-lethal concentrations of CMIT (0.01 and 0.1 mg L-1) for 14 days. Responses in target tissues such as haemolymph (H), digestive gland (DG), and gills (G) were assessed. Cytotoxicity and phagocytosis ability were analysed in haemocytes. Also, cytotoxicity was measured in DG cells along with cell ability to respond to osmotic shock via the Regulatory Volume Decrease (RVD) assay. In G, oxidative stress indexes (protein carbonylation, TBARS, and superoxide dismutase) were measured. Findings indicated alterations in cell physiological functionality and osmoregulatory response as well as high vulnerability of biochemical responses. These results demonstrate the potential toxicity of CMIT on key physiological and biochemical parameters. This basic research exploits potency and lays the groundwork for future studies that will fully elucidate the effects of isothiazolinones on model organisms and the wider ecosystem, and indirectly on human health
Prevalence of infectious and parasitic agents in domesticated cats in the metropolitan region of Niterói, RJ, Brazil
Una breve introduzione agli aiuti di Stato, tra giustificazione economica ed esigenze normative
Il tema degli aiuti di Stato rappresenta una delle tematiche più
complesse dell’ordinamento economico e giuridico europeo, all’interno
del quale si intrecciano le finalità di coesione economico-sociale
con le esigenze di tutela della concorrenza, e gli obiettivi di sviluppo
sostenibile che gli Stati membri perseguono nel rispetto delle regole
comuni dell’Unione
Il processo di modernizzazione degli aiuti di stato tra aspettative e realtà
Ormai da diversi anni, il Consiglio regionale dell’Abruzzo, ha dato
vita a un’intensa collaborazione con l’Università degli studi di Teramo
- Dipartimento di Scienze Politiche, che si è rivelata proficua e qualificante.
In particolare, l’Ente ospita, negli uffici della propria sede istituzionale
di L’Aquila, studenti laureati presso l’Università degli Studi di
Teramo, esperti in materia di politiche europee, coinvolgendoli in attività
di studio, ricerca e produzione di contributi su temi di interesse
del Consiglio regionale correlati alle funzioni allo stesso assegnate nei
processi UE.
Il presente volume raccoglie i contributi di tre giovani laureati sulla
tematica degli aiuti di Stato, al precipuo fine di fornire un quadro
completo e aggiornato dei processi che interessano questo rilevante
settore, nell’ottica di rendere accessibili a un’ampia platea di lettori le
complesse regole che governano la materia, favorendo una maggiore
consapevolezza e prevenendo possibili violazioni.
La scelta di concentrasi sulla tematica degli aiuti di Stato non è
stata casuale, considerata la rilevate importanza che la stessa assume
nell’ambito dell’iter legislativo regionale, ove molti dei progetti di legge
presentati afferiscono a contributi che impattano sulla normativa
degli aiuti di Stato.
L’elaborato presenta, inoltre, uno specifico focus sul PNRR, sugli
aiuti di Stato in materia di cultura e di turismo, in ragione delle recenti
novità e degli aggiornamenti che hanno interessato tali settori, nonché
della risonanza che l’ambito culturale e turistico rivestono, in via
generale, nel panorama regionale abruzzese e particolarmente in ragione
della recente nomina della città di L’Aquila a Capitale della cultura,
circostanza che vedrà il susseguirsi di numerose iniziative culturali
e che attrarrà numerosi turisti, che ben potrebbero intersecare la
tematica degli aiuti di Stato
Transcriptional enhancers in human neuronal differentiation provide clues to neuronal disorders
Genome-wide association studies (GWASs) have identified thousands of variants associated with complex phenotypes, including neuropsychiatric disorders. To better understand their pathogenesis, it is necessary to identify the functional roles of these variants, which are largely located in non-coding DNA regions. Here, we employ a human mesencephalic neuronal cell differentiation model, LUHMES, with sensitive and high-resolution methods to discover enhancers (NET-CAGE), perform DNA conformation analysis (Capture Hi-C) to link enhancers to their target genes, and finally validate selected interactions. We expand the number of known enhancers active in differentiating human LUHMES neurons to 47,350, and find overlap with GWAS variants for Parkinson’s disease and schizophrenia. Our findings reveal a fine-tuned regulation of human neuronal differentiation, even between adjacent developmental stages; provide a valuable resource for further studies on neuronal development, regulation, and disorders; and emphasize the importance of exploring the vast regulatory potential of non-coding DNA and enhancers
Use of artificial intelligence in public sector: threats and prospects
The aim of the article is to analyse the possibilities of using artificial intelligence in the public sector and to identify both the opportunities and threats posed by this digital tool. The authors showed that, thanks to advanced data analysis capabilities, automation of administrative processes, and crisis management, AI can significantly improve the efficiency and quality of public services. However, the implementation of this technology in the public sector is associated with several challenges, including system security, personal data protection, and transparency of decisionmaking processes. In the conclusions, the authors emphasise that the implementation of artificial intelligence in the public sector requires a balanced approach that takes into account both benefits and risks